HUP0001805A3 - 6-benzyl-1,5-dihydro-pyrazolo[3,4-d]-pyrimidin-4-one derivatives, process for their preparation and pharmaceutical compositions containing them - Google Patents

6-benzyl-1,5-dihydro-pyrazolo[3,4-d]-pyrimidin-4-one derivatives, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
HUP0001805A3
HUP0001805A3 HU0001805A HUP0001805A HUP0001805A3 HU P0001805 A3 HUP0001805 A3 HU P0001805A3 HU 0001805 A HU0001805 A HU 0001805A HU P0001805 A HUP0001805 A HU P0001805A HU P0001805 A3 HUP0001805 A3 HU P0001805A3
Authority
HU
Hungary
Prior art keywords
pyrazolo
pyrimidin
dihydro
benzyl
derivatives
Prior art date
Application number
HU0001805A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of HUP0001805A2 publication Critical patent/HUP0001805A2/hu
Publication of HUP0001805A3 publication Critical patent/HUP0001805A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
HU0001805A 1997-03-11 1998-02-26 6-benzyl-1,5-dihydro-pyrazolo[3,4-d]-pyrimidin-4-one derivatives, process for their preparation and pharmaceutical compositions containing them HUP0001805A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19709877A DE19709877A1 (de) 1997-03-11 1997-03-11 1,5-Dihydro-pyrazolo[3,4-d]-pyrimidinon-derivate
PCT/EP1998/001086 WO1998040384A1 (de) 1997-03-11 1998-02-26 1,5-dihydro-pyrazolo[3,4-d]-pyrimidinon-derivate

Publications (2)

Publication Number Publication Date
HUP0001805A2 HUP0001805A2 (hu) 2000-11-28
HUP0001805A3 true HUP0001805A3 (en) 2002-09-30

Family

ID=7822900

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0001805A HUP0001805A3 (en) 1997-03-11 1998-02-26 6-benzyl-1,5-dihydro-pyrazolo[3,4-d]-pyrimidin-4-one derivatives, process for their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (1) US6174884B1 (hu)
EP (1) EP0973774B1 (hu)
JP (1) JP2001514638A (hu)
KR (1) KR20000076124A (hu)
CN (1) CN1151155C (hu)
AT (1) ATE231509T1 (hu)
AU (1) AU727615B2 (hu)
BR (1) BR9807995A (hu)
CA (1) CA2283211A1 (hu)
DE (2) DE19709877A1 (hu)
DK (1) DK0973774T3 (hu)
ES (1) ES2191294T3 (hu)
HK (1) HK1028035A1 (hu)
HU (1) HUP0001805A3 (hu)
IL (1) IL131450A0 (hu)
NZ (1) NZ337724A (hu)
RU (1) RU2219180C2 (hu)
WO (1) WO1998040384A1 (hu)

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DE102004004142A1 (de) 2003-05-09 2004-11-25 Bayer Healthcare Ag 6-Cyclylmethyl- und 6-Alkylmethyl-substituierte Pyrazolopyrimidine
US8044060B2 (en) 2003-05-09 2011-10-25 Boehringer Ingelheim International Gmbh 6-cyclylmethyl- and 6-alkylmethyl pyrazolo[3,4-D]pyrimidines, methods for their preparation and methods for their use to treat impairments of perception, concentration learning and/or memory
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DE10328479A1 (de) 2003-06-25 2005-01-13 Bayer Ag 6-Arylamino-5-cyano-4-pyrimidinone
US20060229242A1 (en) * 2003-08-28 2006-10-12 Altana Phazma Ag Composition comprising a pulmonary surfactant and a pde2 inhibitor
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JP5542196B2 (ja) 2009-03-31 2014-07-09 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １−複素環−１，５−ジヒドロ−ピラゾロ［３，４−ｄ］ピリミジン−４−オン誘導体及びｐｄｅ９ａモジュレーターとしてのそれらの使用
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JP6628805B2 (ja) 2015-02-03 2020-01-15 ファイザー・インク 新規シクロプロパベンゾフラニルピリドピラジンジオン
JO3627B1 (ar) 2015-04-30 2020-08-27 H Lundbeck As إيميدازو بيرازينونات على هيئة مثبطات pde1
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EP3310784B1 (en) 2015-06-17 2020-10-07 Pfizer Inc Tricyclic compounds and their use as phosphodiesterase inhibitors.
KR102148587B1 (ko) 2016-02-23 2020-08-26 화이자 인코포레이티드 6,7-디히드로-5H-피라졸로[5,1-b][1,3]옥사진-2-카르복스아미드 화합물
TWI729109B (zh) 2016-04-12 2021-06-01 丹麥商Ｈ 朗德貝克公司 作爲PDE1抑制劑的1,5-二氫-4H-吡唑并[3,4-d]嘧啶-4-酮和1,5-二氫-4H-吡唑并[4,3-c]吡啶-4-酮
AU2017286868B2 (en) 2016-07-01 2021-11-11 Pfizer Inc. 5,7-dihydro-pyrrolo-pyridine derivatives for treating neurological and neurodegenerative diseases
US10633382B2 (en) * 2016-10-18 2020-04-28 H. Lundbeck A/S Imidazopyrazinones, pyrazolopyrimidinones and pyrazolopyridinones as PDE1 inhibitors
MA46621A (fr) 2016-10-28 2021-06-02 H Lundbeck As Traitements combinés comprenant l'administration d'imidazopyrazinones
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Also Published As

Publication number Publication date
AU727615B2 (en) 2000-12-14
HK1028035A1 (en) 2001-02-02
CN1255133A (zh) 2000-05-31
DE19709877A1 (de) 1998-09-17
AU6824098A (en) 1998-09-29
DE59807011D1 (de) 2003-02-27
JP2001514638A (ja) 2001-09-11
BR9807995A (pt) 2000-03-08
DK0973774T3 (da) 2003-05-05
ATE231509T1 (de) 2003-02-15
CN1151155C (zh) 2004-05-26
HUP0001805A2 (hu) 2000-11-28
NZ337724A (en) 2000-08-25
US6174884B1 (en) 2001-01-16
CA2283211A1 (en) 1998-09-17
EP0973774A1 (de) 2000-01-26
KR20000076124A (ko) 2000-12-26
EP0973774B1 (de) 2003-01-22
RU2219180C2 (ru) 2003-12-20
IL131450A0 (en) 2001-01-28
ES2191294T3 (es) 2003-09-01
WO1998040384A1 (de) 1998-09-17

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