MA46621A - Traitements combinés comprenant l'administration d'imidazopyrazinones - Google Patents

Traitements combinés comprenant l'administration d'imidazopyrazinones

Info

Publication number
MA46621A
MA46621A MA046621A MA46621A MA46621A MA 46621 A MA46621 A MA 46621A MA 046621 A MA046621 A MA 046621A MA 46621 A MA46621 A MA 46621A MA 46621 A MA46621 A MA 46621A
Authority
MA
Morocco
Prior art keywords
imidazopyrazinones
administration
combination treatments
treatments including
combination
Prior art date
Application number
MA046621A
Other languages
English (en)
Inventor
Mikkel Jessing
Karsten Juhl
Jan Kehler
Morten Langgård
Lars Kyhn Rasmussen
Paulo Jorge Vieira Vital
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of MA46621A publication Critical patent/MA46621A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
MA046621A 2016-10-28 2017-10-26 Traitements combinés comprenant l'administration d'imidazopyrazinones MA46621A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA201600660 2016-10-28

Publications (1)

Publication Number Publication Date
MA46621A true MA46621A (fr) 2021-06-02

Family

ID=60302087

Family Applications (1)

Application Number Title Priority Date Filing Date
MA046621A MA46621A (fr) 2016-10-28 2017-10-26 Traitements combinés comprenant l'administration d'imidazopyrazinones

Country Status (18)

Country Link
US (1) US10912773B2 (fr)
EP (1) EP3532053A1 (fr)
JP (1) JP2020500841A (fr)
KR (1) KR20190077349A (fr)
CN (1) CN109803653A (fr)
AR (1) AR109990A1 (fr)
AU (1) AU2017350477A1 (fr)
BR (1) BR112018013084A2 (fr)
CA (1) CA3041595A1 (fr)
CL (1) CL2019001092A1 (fr)
CO (1) CO2019002889A2 (fr)
IL (1) IL265633B (fr)
MA (1) MA46621A (fr)
MX (1) MX2019004859A (fr)
RU (1) RU2019108717A (fr)
SG (1) SG11201903061YA (fr)
WO (1) WO2018078042A1 (fr)
ZA (1) ZA201902090B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201629064A (zh) 2014-10-10 2016-08-16 H 朗德貝克公司 作爲pde1抑制劑之三唑並吡酮
JO3627B1 (ar) 2015-04-30 2020-08-27 H Lundbeck As إيميدازو بيرازينونات على هيئة مثبطات pde1
TWI729109B (zh) 2016-04-12 2021-06-01 丹麥商H 朗德貝克公司 作爲PDE1抑制劑的1,5-二氫-4H-吡唑并[3,4-d]嘧啶-4-酮和1,5-二氫-4H-吡唑并[4,3-c]吡啶-4-酮
EP3529250B1 (fr) 2016-10-18 2023-12-06 H. Lundbeck A/S Imidazopyrazinones, pyrazolopyrimidinones et pyrazolopyridinones en tant qu'inhibiteurs de pde1
SG11201903061YA (en) 2016-10-28 2019-05-30 H Lundbeck As Combination treatments comprising administration of imidazopyrazinones
MX2019004763A (es) 2016-10-28 2019-07-01 H Lundbeck As Tratamientos de combinacion que comprenden imidazopirazinonas para el tratamiento de trastornos psiquiatricos y/o cognitivos.
CA3090219A1 (fr) 2018-02-01 2019-08-08 Japan Tobacco Inc. Compose amide heterocyclique azote et son utilisation a des fins medicales
GB202018412D0 (en) * 2020-11-23 2021-01-06 Exscientia Ltd Malt-1 modulators ii
WO2024042480A1 (fr) 2022-08-26 2024-02-29 Suven Life Sciences Limited Composés hétéroaromatiques pour le traitement de troubles neurologiques

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB973361A (en) 1960-05-11 1964-10-28 Ciba Ltd Pyrazolo-pyrimidines and process for their manufacture
DE19709877A1 (de) 1997-03-11 1998-09-17 Bayer Ag 1,5-Dihydro-pyrazolo[3,4-d]-pyrimidinon-derivate
MY144532A (en) 2001-08-20 2011-09-30 Lundbeck & Co As H Novel method for down-regulation of amyloid
DE10238723A1 (de) 2002-08-23 2004-03-11 Bayer Ag Phenyl-substituierte Pyrazolyprimidine
DE10238722A1 (de) 2002-08-23 2004-03-11 Bayer Ag Selektive Phosphodiesterase 9A-Inhibitoren als Arzneimittel zur Verbesserung kognitiver Prozesse
DE10238724A1 (de) 2002-08-23 2004-03-04 Bayer Ag Alkyl-substituierte Pyrazolpyrimidine
WO2004099211A1 (fr) 2003-05-09 2004-11-18 Bayer Healthcare Ag Pyrazolopyrimidines substituees par 6-cyclylmethyle et 6-alkylmethyle
EP1828192B1 (fr) * 2004-12-21 2014-12-03 Takeda Pharmaceutical Company Limited Inhibiteurs de dipeptidyle peptidase
US20080194592A1 (en) 2005-08-23 2008-08-14 Intra-Cellular Therapies, Inc. Organic Compounds
US8012936B2 (en) 2006-03-29 2011-09-06 New York University Tau fragments for immunotherapy
US9006258B2 (en) 2006-12-05 2015-04-14 Intra-Cellular Therapies, Inc. Method of treating female sexual dysfunction with a PDE1 inhibitor
RS52166B (en) 2007-05-11 2012-08-31 Pfizer Inc. AMINO-HETEROCYCLIC COMPOUNDS
JP2011504892A (ja) 2007-11-30 2011-02-17 ビオティエ セラピーズ ゲゼルシャフト ミット ベシュレンクテル ハフツング ホスホジエステラーゼ10の阻害剤としてのアリール及びヘテロアリール縮合イミダゾ(1,5−a)ピラジン
UA105362C2 (en) 2008-04-02 2014-05-12 Бьорингер Ингельхайм Интернациональ Гмбх 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
PE20110383A1 (es) 2008-09-08 2011-07-15 Boehringer Ingelheim Int Pirazolopirimidinonas como inhibidores de la fosfodiesterasa 9a (pde9a)
MA32941B1 (fr) 2008-12-06 2012-01-02 Intra Cellular Therapies Inc Composes organiques
TWI404721B (zh) 2009-01-26 2013-08-11 Pfizer 胺基-雜環化合物
CN102596221B (zh) 2009-06-10 2019-06-04 纽约大学 病理tau蛋白的免疫靶向
WO2011153136A1 (fr) 2010-05-31 2011-12-08 Intra-Cellular Therapies, Inc. Composés organiques
JP5980207B2 (ja) 2010-08-12 2016-08-31 イーライ リリー アンド カンパニー 抗N3pGluアミロイドβペプチド抗体及びその使用
AU2011305568B2 (en) 2010-09-20 2015-12-10 Ironwood Pharmaceuticals, Inc. Imidazotriazinone compounds
EP2619204A4 (fr) 2010-09-21 2014-08-27 Merck Sharp & Dohme Triazolopyrazinones comme antagonistes des récepteurs p2x7
JO3089B1 (ar) 2010-11-19 2017-03-15 H Lundbeck As مشتقات ايميدازول كمثبطات لانزيمات pde10a
WO2012136552A1 (fr) 2011-04-08 2012-10-11 H. Lundbeck A/S Anticorps spécifiquement dirigés contre la protéine bêta-amyloïde pyroglutamatée
US10561656B2 (en) 2011-06-10 2020-02-18 Intra-Cellular Therapies, Inc. Organic compounds
JP2015531401A (ja) 2011-10-10 2015-11-02 ハー・ルンドベック・アクチエゼルスカベット イミダゾピラジノン骨格を有するpde9i
SG11201403909RA (en) 2012-01-26 2014-10-30 Lundbeck & Co As H Pde9 inhibitors with imidazo triazinone backbone
WO2013192229A1 (fr) 2012-06-18 2013-12-27 Dart Neuroscience (Cayman) Ltd Composés pyridine azolopyrimidin-5-(6h)-ones substitués
EP2970279B1 (fr) 2013-03-15 2020-09-16 Intra-Cellular Therapies, Inc. Composés organiques
JP5783297B2 (ja) 2013-08-06 2015-09-24 株式会社デンソー 力学量センサ
EA031132B1 (ru) 2014-02-19 2018-11-30 Х. Лундбекк А/С 2-амино-3,5,5-трифтор-3,4,5,6-тетрагидропиридины в качестве ингибиторов bace1 для лечения болезни альцгеймера
JP5797815B1 (ja) 2014-06-27 2015-10-21 細田建設株式会社 後施工アンカー及びその施工方法
TWI599358B (zh) 2014-09-16 2017-09-21 美國禮來大藥廠 組合療法
US20160083400A1 (en) 2014-09-18 2016-03-24 Sunovion Pharmaceuticals Inc. Tricyclic guanidine derivative
WO2016042775A1 (fr) 2014-09-18 2016-03-24 Sunovion Pharmaceuticals Inc. Dérivé tricyclique
US20160083391A1 (en) 2014-09-18 2016-03-24 Sunovion Pharmaceuticals Inc. Tricyclic piperazine derivative
TW201629064A (zh) 2014-10-10 2016-08-16 H 朗德貝克公司 作爲pde1抑制劑之三唑並吡酮
MA40941A (fr) 2014-11-10 2017-09-19 H Lundbeck As 2-amino-5,5-difluoro-6-(fluorométhyl)-6-phényl-3,4,5,6-tétrahydropyridines comme inhibiteurs de bace1
CR20170187A (es) 2014-11-10 2018-02-01 H Lundbeck As 2-Amino-3,5-difluoro-6-metil-6-fenil-3,4,5,6-tetrahidropiridinas en calidad de inhibidores de BACE1 para el tratamiento de la enfermedad de Alzheimer
JO3458B1 (ar) 2014-11-10 2020-07-05 H Lundbeck As 2- أمينو-6- (دايفلوروميثيل) – 5، 5- ديفلورو-6-فينيل-3،4، 5، 6-تيتراهيدروبيريدين كمثبطات bace1
WO2016147659A1 (fr) 2015-03-16 2016-09-22 Sumitomo Dainippon Pharma Co., Ltd. Dérivé imidazolo bicyclique
US20160311831A1 (en) 2015-04-22 2016-10-27 H. Lundbeck A/S Imidazotriazinones as PDE1 Inhibitors
JO3627B1 (ar) 2015-04-30 2020-08-27 H Lundbeck As إيميدازو بيرازينونات على هيئة مثبطات pde1
JO3711B1 (ar) 2015-07-13 2021-01-31 H Lundbeck As أجسام مضادة محددة لبروتين تاو وطرق استعمالها
US10011596B2 (en) 2015-08-12 2018-07-03 H. Lundbeck A/S 2-amino-3-fluoro-3-(fluoromethyl)-6-methyl-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors
AR107456A1 (es) 2016-02-12 2018-05-02 Lilly Co Eli Inhibidor de pde1
TWI729109B (zh) 2016-04-12 2021-06-01 丹麥商H 朗德貝克公司 作爲PDE1抑制劑的1,5-二氫-4H-吡唑并[3,4-d]嘧啶-4-酮和1,5-二氫-4H-吡唑并[4,3-c]吡啶-4-酮
EP3474937A1 (fr) * 2016-06-23 2019-05-01 Avent, Inc. Élément formant bobine échogène destiné à un ensemble cathéter
JP2018076285A (ja) 2016-09-14 2018-05-17 大日本住友製薬株式会社 二環性イミダゾロ誘導体を含む医薬
EP3529250B1 (fr) 2016-10-18 2023-12-06 H. Lundbeck A/S Imidazopyrazinones, pyrazolopyrimidinones et pyrazolopyridinones en tant qu'inhibiteurs de pde1
MX2019004763A (es) 2016-10-28 2019-07-01 H Lundbeck As Tratamientos de combinacion que comprenden imidazopirazinonas para el tratamiento de trastornos psiquiatricos y/o cognitivos.
SG11201903061YA (en) 2016-10-28 2019-05-30 H Lundbeck As Combination treatments comprising administration of imidazopyrazinones

Also Published As

Publication number Publication date
SG11201903061YA (en) 2019-05-30
RU2019108717A3 (fr) 2021-01-29
AU2017350477A1 (en) 2019-04-18
JP2020500841A (ja) 2020-01-16
US10912773B2 (en) 2021-02-09
IL265633B (en) 2021-05-31
AR109990A1 (es) 2019-02-13
EP3532053A1 (fr) 2019-09-04
ZA201902090B (en) 2020-10-28
MX2019004859A (es) 2019-06-20
CO2019002889A2 (es) 2019-06-19
CL2019001092A1 (es) 2019-07-05
CN109803653A (zh) 2019-05-24
WO2018078042A1 (fr) 2018-05-03
BR112018013084A2 (pt) 2018-12-11
KR20190077349A (ko) 2019-07-03
IL265633A (en) 2019-05-30
RU2019108717A (ru) 2020-11-30
CA3041595A1 (fr) 2018-05-03
US20190282572A1 (en) 2019-09-19

Similar Documents

Publication Publication Date Title
MA46621A (fr) Traitements combinés comprenant l'administration d'imidazopyrazinones
MA45192A (fr) Traitement d'association
JP2016028092A5 (fr)
JP2016065085A5 (fr)
DK3474804T3 (da) Medicinsk forbinding
MA42844A (fr) Combinaisons thérapeutiques comprenant des immunoconjugués anti-folr1
DK3408265T3 (da) Terapeutiske forbindelser
DK3474803T3 (da) Medicinsk forbinding
MA48442A (fr) Structure d'extérieur
DK3452465T3 (da) Substituerede 2,4-diaminoquinolinderivater til anvendelse til behandling af proliferative sygdomme
MA42611A (fr) Traitement combiné comprenant l'administration de 2-amino-3,5,5-trifluoro-3,4,5,6-tétrahydropyridines
IT201600081379A1 (it) Composizione farmaceutica per uso nel trattamento delle patologie prostatiche.
DK3454717T3 (da) Medicinsk endoskoptilbehør, medicinske endoskoper omfattende tilbehøret samt anvendelse deraf
IT201700123080A1 (it) Macchina per l'assemblaggio di dispositivi medicali.
IT201700035964A1 (it) “divisorio per boiserie”
ITUA20163609A1 (it) "micro-cogeneratore".
UA35778S (uk) Стілець дитячий
UA33980S (uk) Стілець дитячий
UA35163S (uk) Стілець дитячий
MA51199A (fr) Agents d'imagerie
IT201700090331A1 (it) "lopemide"
UA38939S (uk) Велобіг-мотоцикл дитячий
IT201700071679A1 (it) Remembebe'
IT201700033290A1 (it) “letto migliorato”
DK3412339T3 (da) Indretning til fototerapi eller Grovers sygdom