HUE053232T2 - Sejtek és eljárások ramnolipidek elõállítására - Google Patents

Sejtek és eljárások ramnolipidek elõállítására

Info

Publication number
HUE053232T2
HUE053232T2 HUE18184367A HUE18184367A HUE053232T2 HU E053232 T2 HUE053232 T2 HU E053232T2 HU E18184367 A HUE18184367 A HU E18184367A HU E18184367 A HUE18184367 A HU E18184367A HU E053232 T2 HUE053232 T2 HU E053232T2
Authority
HU
Hungary
Prior art keywords
rhamnolipids
cells
preparation
Prior art date
Application number
HUE18184367A
Other languages
English (en)
Inventor
Steffen Schaffer
Mirja Wessel
Anja Hecker
Nadine Stein
Original Assignee
Evonik Operations Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Operations Gmbh filed Critical Evonik Operations Gmbh
Publication of HUE053232T2 publication Critical patent/HUE053232T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/16Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/78Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y306/00Hydrolases acting on acid anhydrides (3.6)
    • C12Y306/04Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; involved in cellular and subcellular movement (3.6.4)
    • C12Y306/04013RNA helicase (3.6.4.13)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
HUE18184367A 2010-07-28 2011-07-20 Sejtek és eljárások ramnolipidek elõállítására HUE053232T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102010032484A DE102010032484A1 (de) 2010-07-28 2010-07-28 Zellen und Verfahren zur Herstellung von Rhamnolipiden

Publications (1)

Publication Number Publication Date
HUE053232T2 true HUE053232T2 (hu) 2021-06-28

Family

ID=44478868

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE11734101A HUE042573T2 (hu) 2010-07-28 2011-07-20 Sejtek és eljárás ramnolipidek elõállítására
HUE18184367A HUE053232T2 (hu) 2010-07-28 2011-07-20 Sejtek és eljárások ramnolipidek elõállítására

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE11734101A HUE042573T2 (hu) 2010-07-28 2011-07-20 Sejtek és eljárás ramnolipidek elõállítására

Country Status (11)

Country Link
US (2) US9005928B2 (hu)
EP (2) EP2598646B1 (hu)
JP (2) JP6066908B2 (hu)
CN (2) CN108587995B (hu)
BR (2) BR112013002124B1 (hu)
CA (1) CA2806430C (hu)
DE (1) DE102010032484A1 (hu)
ES (2) ES2837485T3 (hu)
HU (2) HUE042573T2 (hu)
RU (1) RU2619877C2 (hu)
WO (1) WO2012013554A1 (hu)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006025821A1 (de) 2006-06-02 2007-12-06 Degussa Gmbh Ein Enzym zur Herstellung von Mehylmalonatsemialdehyd oder Malonatsemialdehyd
DE102007052463A1 (de) * 2007-11-02 2009-05-07 Evonik Degussa Gmbh Fermentative Gewinnung von Aceton aus erneuerbaren Rohstoffen mittels neuen Stoffwechselweges
DE102007060705A1 (de) * 2007-12-17 2009-06-18 Evonik Degussa Gmbh ω-Aminocarbonsäuren oder ihre Lactame, herstellende, rekombinante Zellen
DE102008002715A1 (de) * 2008-06-27 2009-12-31 Evonik Röhm Gmbh 2-Hydroxyisobuttersäure produzierende rekombinante Zelle
DE102009009580A1 (de) 2009-02-19 2010-08-26 Evonik Degussa Gmbh Verfahren zur Herstellung freier Säuren aus ihren Salzen
DE102009046626A1 (de) 2009-11-11 2011-05-12 Evonik Degussa Gmbh Candida tropicalis Zellen und deren Verwendung
DE102009046623A1 (de) 2009-11-11 2011-05-12 Evonik Röhm Gmbh Verwendung eines zu einem MeaB-Protein homologen Proteins zur Erhöhung der enzymatischen Aktivität einer 3-Hydroxycarbonsäure-CoA-Mutase
DE102010014680A1 (de) 2009-11-18 2011-08-18 Evonik Degussa GmbH, 45128 Zellen, Nukleinsäuren, Enzyme und deren Verwendung sowie Verfahren zur Herstellung von Sophorolipiden
DE102010015807A1 (de) 2010-04-20 2011-10-20 Evonik Degussa Gmbh Biokatalytisches Oxidationsverfahren mit alkL-Genprodukt
DE102011004465A1 (de) 2010-09-10 2012-03-15 Evonik Degussa Gmbh Verfahren zur direkten Aminierung sekundärer Alkohole mit Ammoniak zu primären Aminen
DE102010043470A1 (de) 2010-11-05 2012-05-10 Evonik Degussa Gmbh Zusammensetzung aus Polyamiden mit niedriger Konzentration an Carbonsäureamidgruppen und elektrisch leitfähigem Kohlenstoff
DE102011075162A1 (de) 2010-12-08 2012-06-14 Evonik Degussa Gmbh Verfahren zur homogen-katalysierte, hochselektiven direkten Aminierung von primären Alkoholen mit Ammoniak zu primären Aminen bei hohem Volumenverhältnis von Flüssig- zu Gasphase und/oder hohen Drücken
BR112013021208A2 (pt) 2011-02-21 2019-09-24 Evonik Degussa Gmbh processo para aminação direta de álcoois com amônia para formar aminas primárias por meio de sistema catalisador xantphos
ES2604335T3 (es) 2011-07-20 2017-03-06 Evonik Degussa Gmbh Oxidación y aminación de alcoholes primarios
EP2573172A1 (en) 2011-09-21 2013-03-27 Heinrich-Heine-Universität Düsseldorf Means and methods for rhamnolipid production
DE102011084518A1 (de) 2011-10-14 2013-04-18 Evonik Industries Ag Verwendung einer Mehrschichtfolie mit Polyamid- und Polyesterschichten fürdie Herstellung photovoltaischer Module
EP2602328A1 (de) 2011-12-05 2013-06-12 Evonik Industries AG Verfahren zur Oxidation von Alkanen unter Verwendung einer AlkB Alkan 1-Monooxygenase
EP2607479A1 (en) 2011-12-22 2013-06-26 Evonik Industries AG Biotechnological production of alcohols and derivatives thereof
EP2631298A1 (en) 2012-02-22 2013-08-28 Evonik Industries AG Biotechnological method for producing butanol and butyric acid
EP2639308A1 (de) 2012-03-12 2013-09-18 Evonik Industries AG Enzymatische omega-Oxidation und -Aminierung von Fettsäuren
EP2647696A1 (de) 2012-04-02 2013-10-09 Evonik Degussa GmbH Verfahren zur aeroben Herstellung von Alanin oder einer unter Verbrauch von Alanin entstehenden Verbindung
WO2014039940A1 (en) * 2012-09-10 2014-03-13 Logos Technologies Llc Cells and methods for the production of rhamnolipids
DE102012221519A1 (de) 2012-11-26 2014-05-28 Evonik Industries Ag Verfahren zur Isolierung von Rhamnolipiden
EP2746400A1 (de) 2012-12-21 2014-06-25 Evonik Industries AG Herstellung von Aminen und Diaminen aus einer Carbonsäure oder Dicarbonsäure oder eines Monoesters davon
DE102013205756A1 (de) * 2013-04-02 2014-10-02 Evonik Industries Ag Mischungszusammensetzung enthaltend Rhamnolipide
DE102013205755A1 (de) 2013-04-02 2014-10-02 Evonik Industries Ag Waschmittelformulierung für Textilien enthaltend Rhamnolipide mit einem überwiegenden Gehalt an di-Rhamnolipiden
US10190144B2 (en) 2013-06-06 2019-01-29 The United States Of America, As Represented By The Secretary Of Agriculture Production of dirhamnose-lipid in recombinant nonpathogenic bacterium Pseudomonas chlororaphis
EP2949214A1 (en) * 2014-05-26 2015-12-02 Evonik Degussa GmbH Methods of producing rhamnolipids
PL3023431T3 (pl) * 2014-11-19 2017-07-31 Evonik Degussa Gmbh Stężone kompozycje ramnolipidowe o niskiej lepkości
US9884883B2 (en) * 2015-01-12 2018-02-06 Logos Technologies, Llc Production of rhamnolipid compositions
US20180066297A1 (en) * 2015-02-19 2018-03-08 Evonik Degussa Gmbh Rhamnolipid synthesis
CA2937594A1 (en) 2015-02-26 2016-08-26 Evonik Degussa Gmbh Alkene production
EP3061442A1 (de) 2015-02-27 2016-08-31 Evonik Degussa GmbH Zusammensetzung enthaltend Rhamnolipid und Siloxan
ES2792029T3 (es) * 2015-05-05 2020-11-06 Stepan Co Un procedimiento semicontinuo para la preparación de ramnolípidos con alto rendimiento y título
WO2017006252A1 (en) 2015-07-08 2017-01-12 Rheinisch-Westfaelische Technische Hochschule Aachen (Rwth) Extracellular production of designer hydroxyalkanoyloxy alkanoic acids with recombinant bacteria
WO2017144317A1 (de) 2016-02-22 2017-08-31 Evonik Degussa Gmbh Rhamnolipidester als nichtionische tenside zur kosmetischen anwendung
CN108699096B (zh) 2016-02-22 2021-11-26 赢创运营有限公司 用于头发香味保留的鼠李糖脂酰胺
JP2019508564A (ja) 2016-03-18 2019-03-28 エボニック デグサ ゲーエムベーハーEvonik Degussa GmbH 少なくとも1種のバイオサーファクタントがその上に含まれる無機固体担体を含む顆粒
BR112019008320A2 (pt) * 2016-10-24 2020-01-28 Evonik Degussa Gmbh células e método para produzir ramnolipídios com o uso de transportadores de glicose alternativos
BR112019008321A2 (pt) * 2016-10-24 2020-01-28 Evonik Degussa Gmbh célula e método de produção de ramnolipídeo que tem atividade de glicose desidrogenase reduzida e seu uso
EP3577126B1 (en) 2017-02-06 2023-09-06 Stepan Company Decolorization of concentrated rhamnolipid composition
EP3662075A4 (en) * 2017-07-31 2021-05-19 Stepan Company IMPROVED PRODUCTION OF RHAMNOLIPIDS USING AT LEAST TWO SOURCES OF CARBON
WO2019038125A1 (de) 2017-08-24 2019-02-28 Evonik Degussa Gmbh Rhamnolipidderivate als emulgatoren und dispergierhilfsmittel
CN108060111B (zh) * 2017-10-27 2021-06-04 中国科学院微生物研究所 一种提高鼠李糖脂产量的铜绿假单胞菌及其构建方法
BR112020015687A2 (pt) * 2018-02-09 2020-12-08 Evonik Operations Gmbh Célula microbiana para produzir pelo menos um lipídeo, método e uso da mesma
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
CN112481335A (zh) * 2019-09-11 2021-03-12 万华化学集团股份有限公司 一种鼠李糖脂发酵方法
BR112022018009A2 (pt) 2020-03-11 2022-11-08 Evonik Operations Gmbh Composição, método para preparar uma formulação e uso de trietil citrato
EP4125793A1 (de) 2020-03-24 2023-02-08 Evonik Operations GmbH Zusammensetzungen enthaltend rhamnolipid, alkyl-polyglykosid und acyl-lactylat
CN116249706A (zh) 2020-07-22 2023-06-09 赢创运营有限公司 新型鼠李糖脂低聚酯
CN114438000B (zh) * 2020-11-05 2024-02-27 万华化学(四川)有限公司 一株铜绿假单胞菌及其构建方法与应用
WO2023198511A1 (en) * 2022-04-13 2023-10-19 Evonik Operations Gmbh Process for the fermentative production of a biosurfactant
CN115290765B (zh) * 2022-04-28 2024-02-13 华东理工大学 一种羧酸标记hplc-uv定量检测鼠李糖脂的方法
EP4155371A1 (en) 2022-08-29 2023-03-29 Evonik Operations GmbH Composition rich in mono-rhamnolipids

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US601494A (en) 1898-03-29 Spar for vessels
NL301993A (hu) 1962-12-18
US4601893A (en) 1984-02-08 1986-07-22 Pfizer Inc. Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
EP0473869A1 (de) 1990-08-28 1992-03-11 Landis & Gyr Business Support AG Verfahren zur automatischen Sendewiederholung eines Telegramms bei dessen fehlerhaftem Empfang
DE4027453A1 (de) 1990-08-30 1992-03-05 Degussa Neue plasmide aus corynebacterium glutamicum und davon abgeleitete plasmidvektoren
DE4440118C1 (de) 1994-11-11 1995-11-09 Forschungszentrum Juelich Gmbh Die Genexpression in coryneformen Bakterien regulierende DNA
JP4327909B2 (ja) 1996-11-13 2009-09-09 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 組み換え生物による1,3―プロパンジオールの生産方法
JPH10229891A (ja) 1997-02-20 1998-09-02 Mitsubishi Rayon Co Ltd マロン酸誘導体の製造法
US6551795B1 (en) * 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
US20040033549A1 (en) * 1999-09-03 2004-02-19 Greenberg E. Peter Quorum sensing signaling in bacteria
EP1083225A1 (de) 1999-09-09 2001-03-14 Degussa-Hüls Aktiengesellschaft Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien
DE10031999A1 (de) 1999-09-09 2001-04-19 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien
US6713289B2 (en) 1999-10-05 2004-03-30 Degussa Ag Nucleotide sequences which code for the eno gene
DE19953206A1 (de) * 1999-11-05 2001-05-10 Degussa Plasmide aus Corynebacterium glutamicum und deren Verwendung
GB0228444D0 (en) * 2002-12-05 2003-01-08 Plant Bioscience Ltd Bioremediation with transgenic plants
CN100584841C (zh) * 2007-08-08 2010-01-27 暨南大学 穿心莲内酯衍生物及其在制药中的应用
WO2014039940A1 (en) * 2012-09-10 2014-03-13 Logos Technologies Llc Cells and methods for the production of rhamnolipids
EP2949214A1 (en) * 2014-05-26 2015-12-02 Evonik Degussa GmbH Methods of producing rhamnolipids
CN104830889B (zh) * 2015-03-06 2019-01-25 西安海格生物技术研究所有限公司 一种铜绿假单胞菌高产鼠李糖脂的基因重组方法
CN106755031B (zh) * 2016-11-14 2020-04-17 自然资源部天津海水淡化与综合利用研究所 鼠李糖脂生产质粒及其构建方法与大肠杆菌工程菌和应用

Also Published As

Publication number Publication date
RU2013108700A (ru) 2014-09-10
CA2806430C (en) 2019-06-25
US20130130319A1 (en) 2013-05-23
CN108587995A (zh) 2018-09-28
CA2806430A1 (en) 2012-02-02
CN103038357A (zh) 2013-04-10
EP3418388A1 (de) 2018-12-26
DE102010032484A1 (de) 2012-02-02
JP2017060523A (ja) 2017-03-30
US20150247151A1 (en) 2015-09-03
JP6461078B2 (ja) 2019-01-30
JP6066908B2 (ja) 2017-01-25
EP2598646B1 (de) 2018-11-07
CN103038357B (zh) 2018-05-25
BR112013002124A2 (pt) 2016-09-20
ES2837485T3 (es) 2021-06-30
US9580720B2 (en) 2017-02-28
EP3418388B1 (de) 2020-10-28
RU2619877C2 (ru) 2017-05-18
ES2713479T3 (es) 2019-05-22
JP2013537411A (ja) 2013-10-03
WO2012013554A1 (de) 2012-02-02
US9005928B2 (en) 2015-04-14
BR112013002124B1 (pt) 2021-08-31
CN108587995B (zh) 2022-04-01
EP2598646A1 (de) 2013-06-05
BR122020023808B1 (pt) 2022-01-11
HUE042573T2 (hu) 2019-07-29

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