HUE026044T2 - Formulációk és eljárások amyloidozis kezelésére - Google Patents

Formulációk és eljárások amyloidozis kezelésére Download PDF

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Publication number
HUE026044T2
HUE026044T2 HUE06795492A HUE06795492A HUE026044T2 HU E026044 T2 HUE026044 T2 HU E026044T2 HU E06795492 A HUE06795492 A HU E06795492A HU E06795492 A HUE06795492 A HU E06795492A HU E026044 T2 HUE026044 T2 HU E026044T2
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HU
Hungary
Prior art keywords
subject
mean
compound
formula
amyloidosis
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HUE06795492A
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English (en)
Inventor
Denis Garceau
Wendy Hauck
Richard Briand
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Kiacta Sarl
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Publication of HUE026044T2 publication Critical patent/HUE026044T2/hu

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Claims (5)

  1. b za öaóa ins tgeoyosaaoi: L G ptgyszsireszuu koinpoziokk a-neiy tartalmaz i ..kpnspásKÓsznikexaYa; vägy rútnak kybgVSzedsaGkeg tdibgadhstb sóját íeLhoxzoálássu eltárásbatg aorely amyloid társított betegség kezelésén.-vagy ktegelozésése szolgál alaoybix;. ahol a:z 3 :>-»ropatsds-:Vtdlbose·. vagy amzak gydgysKerészetileg >dk;gadhs.tó séta adagokba körülbetnl ; 20b tkg naponta kétszer kreatnat· ckarence rara 4b -ni. as in e-oSvo. adagolása: körálbdni áOb mg. kapom a ásószer kreatlnba olearekce ráta 30 és 40 mLéaria korok esőtek. vagy adagolása körülbelül 400 sag naponta kétszer kreatkók cledesee ráta 20 ág 20 ad., min körött esesék
  2. 2, Az ;, igénypont szerinti gyógyszerészeti kompozíció léi használásra. okol a gyógyszerészetlkg díógadhatö só 1 A-ptopantkszdiöksae dieA-rsten só. .'·. A.:··: I, vagy 2, lg en y posa, szentül gyógyszerészeti kotnpozk:k> iéikasználásm, ahol a kontgozielo továbbá tanaimaz: gyögyszerészeiileg elmgtidhatd Ixxdozösnsyagot.
  3. 4. Aa ! -à. igékypoosok bármelyike szerinti gyógyszerészeti kotnpozieio kdkasznàlàxra, ahol na arnylokl társítod betegség AA azoyknoozis.
  4. 5, Aa 14. igenypoibok bánöclyike szezinb gyógyszerészeit kompozido lelhaszkslasra. ahoi s gyógyszerészet; íormntádO etd oéiiaíl tsdagelandó. δ. Ar 5.. igékyneot szerinti gyógyszerészek kompoddá teihaszadzsra. ahoi ar «?i nelkd; adagolás a biorekdeikczésze állás- kb 25%-os vagy anas ; nagyobb növekedései eredményezi összebastmlitva. az étellel tőkéké adagolássei,
  5. 7, Az S. tgéttygoní szerétül gyógyszerészeti kompozíció áöbasznalá>.ru. ahol a tunnsiaoté legalább i vagy 2 okival bármely étkezes dob vagy után van adagolva. 5 Λ $. igénypont szerint; gyógyszerészed ktünpozíciö íelitasználásra, áltól a bxnxdáeul legalább 1 étával étkezés előd vagy legalább 2 órávái étkezés sván ox; adagok n.
HUE06795492A 2005-04-15 2006-04-17 Formulációk és eljárások amyloidozis kezelésére HUE026044T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67186605P 2005-04-15 2005-04-15

Publications (1)

Publication Number Publication Date
HUE026044T2 true HUE026044T2 (hu) 2016-05-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
HUE06795492A HUE026044T2 (hu) 2005-04-15 2006-04-17 Formulációk és eljárások amyloidozis kezelésére

Country Status (25)

Country Link
US (3) US8178580B2 (hu)
EP (2) EP2944308A1 (hu)
JP (2) JP2008535906A (hu)
KR (2) KR20130133915A (hu)
CN (2) CN101528216A (hu)
AU (1) AU2006264498B2 (hu)
BR (1) BRPI0610592A2 (hu)
CA (1) CA2582556C (hu)
DK (1) DK1885350T3 (hu)
EA (1) EA018898B1 (hu)
ES (1) ES2534553T3 (hu)
HK (2) HK1116686A1 (hu)
HR (1) HRP20150320T1 (hu)
HU (1) HUE026044T2 (hu)
IL (2) IL186544A (hu)
ME (1) ME02149B (hu)
MX (1) MX2007012525A (hu)
NO (1) NO20075815L (hu)
PL (1) PL1885350T3 (hu)
PT (1) PT1885350E (hu)
RS (1) RS54050B1 (hu)
SI (1) SI1885350T1 (hu)
TW (1) TW200716088A (hu)
WO (1) WO2007004072A2 (hu)
ZA (1) ZA200709825B (hu)

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JP2013501733A (ja) 2009-08-10 2013-01-17 ビーエイチアイ リミテッド パートナーシップ １，３−プロパンジスルホン酸を送達するための方法、化合物、および組成物
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WO2016023911A1 (en) * 2014-08-11 2016-02-18 Kiacta Sàrl Use of 1,3-propanedisulfonic acid or salts thereof to prevent the onset of amyloidosis in select populations
CN116143672B (zh) * 2023-02-28 2024-03-29 卫星化学股份有限公司 水溶性抗氧剂及其制备方法和应用

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US20060252829A1 (en) 2006-11-09
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