BR0016652A - Métodos para inibir angiopatia amilóide cerebral, para tratar um estado de doença caracterizado por angiopatia amilóide cerebral em um indivìduo, e para diagnosticar angiopatia amilóide cerebral em um indivìduo - Google Patents
Métodos para inibir angiopatia amilóide cerebral, para tratar um estado de doença caracterizado por angiopatia amilóide cerebral em um indivìduo, e para diagnosticar angiopatia amilóide cerebral em um indivìduoInfo
- Publication number
- BR0016652A BR0016652A BR0016652-9A BR0016652A BR0016652A BR 0016652 A BR0016652 A BR 0016652A BR 0016652 A BR0016652 A BR 0016652A BR 0016652 A BR0016652 A BR 0016652A
- Authority
- BR
- Brazil
- Prior art keywords
- amyloid angiopathy
- cerebral amyloid
- individual
- methods
- treat
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17187799P | 1999-12-23 | 1999-12-23 | |
PCT/IB2000/002078 WO2001085093A2 (en) | 1999-12-23 | 2000-12-22 | Compounds and methods for modulating cerebral amyloid angiopathy |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0016652A true BR0016652A (pt) | 2002-11-19 |
Family
ID=22625484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0016652-9A BR0016652A (pt) | 1999-12-23 | 2000-12-22 | Métodos para inibir angiopatia amilóide cerebral, para tratar um estado de doença caracterizado por angiopatia amilóide cerebral em um indivìduo, e para diagnosticar angiopatia amilóide cerebral em um indivìduo |
Country Status (11)
Country | Link |
---|---|
US (2) | US6670399B2 (pt) |
EP (1) | EP1251837A2 (pt) |
JP (1) | JP2003532656A (pt) |
KR (3) | KR20080003945A (pt) |
CN (1) | CN1434706A (pt) |
AU (1) | AU8431301A (pt) |
BR (1) | BR0016652A (pt) |
CA (1) | CA2395314A1 (pt) |
IL (1) | IL150374A0 (pt) |
MX (1) | MXPA02006196A (pt) |
WO (1) | WO2001085093A2 (pt) |
Families Citing this family (67)
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US20040208875A1 (en) * | 1995-03-15 | 2004-10-21 | Queen's University At Kingston | Method for treating amyloidosis |
WO1997021728A1 (en) | 1995-12-12 | 1997-06-19 | Karolinska Innovations Ab | PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b) |
US20020022657A1 (en) * | 1998-02-11 | 2002-02-21 | Francine Gervais | Methods for modulating neuronal cell death |
US6310073B1 (en) * | 1998-07-28 | 2001-10-30 | Queen's University At Kingston | Methods and compositions to treat glycosaminoglycan-associated molecular interactions |
US7060670B1 (en) * | 1999-05-05 | 2006-06-13 | Neurochem (International) Limited | Stereoselective antifibrillogenic peptides and peptidomimetics thereof |
AU5994900A (en) * | 1999-07-09 | 2001-01-30 | Isis Innovation Limited | Compounds for inhibiting diseases and preparing cells for transplantation |
US20070135337A2 (en) * | 1999-11-29 | 2007-06-14 | Neurochem (International) Limited | Vaccine for the Prevention and Treatment of Alzheimer's and Amyloid Related Diseases |
US20020094335A1 (en) * | 1999-11-29 | 2002-07-18 | Robert Chalifour | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases |
BR0016652A (pt) * | 1999-12-23 | 2002-11-19 | Neurochem Inc | Métodos para inibir angiopatia amilóide cerebral, para tratar um estado de doença caracterizado por angiopatia amilóide cerebral em um indivìduo, e para diagnosticar angiopatia amilóide cerebral em um indivìduo |
US7311893B2 (en) * | 2000-07-25 | 2007-12-25 | Neurochem (International) Limited | Amyloid targeting imaging agents and uses thereof |
JP2005531508A (ja) * | 2002-03-01 | 2005-10-20 | メルク エンド カムパニー インコーポレーテッド | Edg受容体作動薬としてのアミノアルキルホスホネートおよび関連化合物 |
JP2006525226A (ja) * | 2002-12-24 | 2006-11-09 | ニューロケム (インターナショナル) リミテッド | β−アミロイド関連疾患の治療のための治療用製剤 |
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
EP1477493A1 (en) * | 2003-05-15 | 2004-11-17 | Bayer HealthCare AG | Isotope coded affinity tags |
EP1646659B1 (en) * | 2003-06-23 | 2014-05-14 | Kiacta Sàrl | Method for the preparation of 1,3-propane disulfonic acid compounds |
AU2011250847B2 (en) * | 2003-06-23 | 2013-06-20 | Bhi Limited Partnership | Methods and compositions for treating amyloid-related diseases |
AU2004249527A1 (en) * | 2003-06-23 | 2004-12-29 | Bellus Health (International) Limited | Methods and compositions for treating amyloid-related diseases |
US20060079578A1 (en) * | 2003-06-23 | 2006-04-13 | Julie Laurin | Pharmaceutical formulations of amyloid inhibiting compounds |
US20050142191A1 (en) * | 2003-06-23 | 2005-06-30 | Neurochem (International) Limited | Pharmaceutical formulations of amyloid inhibiting compounds |
US7244764B2 (en) * | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
US20070010573A1 (en) | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
US7414076B2 (en) * | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
US7262223B2 (en) | 2004-01-23 | 2007-08-28 | Neurochem (International) Limited | Amidine derivatives for treating amyloidosis |
EP1841460A2 (en) * | 2004-06-18 | 2007-10-10 | Neurochem (International) Limited | Therapeutic formulations for the treatment of beta-amyloid related diseases |
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CA2574460A1 (en) | 2004-07-23 | 2006-02-02 | Sigma-Aldrich Co. | High stability diionic liquid salts |
US8168830B2 (en) | 2004-07-23 | 2012-05-01 | Sigma-Aldrich Co. Llc | High stability diionic liquid salts |
WO2006017752A2 (en) * | 2004-08-05 | 2006-02-16 | Ivax Corporation | Sulfated oligosaccharides |
EP1817305A2 (en) * | 2004-11-16 | 2007-08-15 | Neurochem (International) Limited | Compounds for the treatment of cns and amyloid associated diseases |
EP1837034A4 (en) * | 2004-11-30 | 2009-08-05 | Anges Mg Inc | MEDICATION FOR ALZHEIMER'S DISEASE |
EP1836161B1 (en) * | 2004-12-22 | 2016-07-20 | BHI Limited Partnership | Methods and compositions for treating amyloid-related diseases |
CN101193628A (zh) * | 2005-04-12 | 2008-06-04 | 神经化学(国际)有限公司 | 淀粉样蛋白抑制性化合物的药物制剂 |
TW200716088A (en) * | 2005-04-15 | 2007-05-01 | Neurochem Int Ltd | Formulations and methods for treating amyloidosis |
US20070049638A1 (en) * | 2005-07-21 | 2007-03-01 | Neurochem (International) Limited | Polymorphic forms of 3-amino-1-propanesulfonic acid |
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KR101439828B1 (ko) | 2005-11-30 | 2014-09-17 | 애브비 인코포레이티드 | 아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도 |
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US8188046B2 (en) * | 2006-10-16 | 2012-05-29 | University Of South Florida | Amyloid beta peptides and methods of use |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
JP2010513219A (ja) * | 2006-12-22 | 2010-04-30 | ベラス ヘルス (インターナショナル) リミテッド | 腎臓の疾患、糖尿病性腎症及び脂質代謝異常の治療 |
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WO2008104386A2 (en) | 2007-02-27 | 2008-09-04 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
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GB0708507D0 (en) * | 2007-05-02 | 2007-06-13 | Queen Mary & Westfield College | Substituted phosphonates and their use |
US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
US20100137258A1 (en) * | 2007-08-01 | 2010-06-03 | Francine Acher | Thiophosphi(o)nic acid derivatives and their therapeutical applications |
US20090076167A1 (en) * | 2007-09-17 | 2009-03-19 | Protia, Llc | Deuterium-enriched tramiprosate |
EP2238166B1 (en) | 2007-10-05 | 2013-11-27 | Genentech, Inc. | Use of anti-amyloid beta antibody in ocular diseases |
US8231895B2 (en) | 2008-05-22 | 2012-07-31 | Universidade De Coimbra | Targeted delivery to human diseases and disorders |
EP2180003A1 (en) * | 2008-10-21 | 2010-04-28 | Zentiva, k.s. | Preparation of ibandronate trisodium |
US9023767B2 (en) * | 2009-05-07 | 2015-05-05 | Memorial Sloan-Kettering Cancer Center | γ-Secretase substrates and methods of use |
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EP2289900A1 (en) * | 2009-08-26 | 2011-03-02 | Humboldt Universität zu Berlin | Bisphosphonates as inhibitors of acid sphingomyelinase |
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US9632088B2 (en) | 2010-09-07 | 2017-04-25 | Memorial Sloan-Kettering Cancer Center | Methods and compositions for gamma-secretase assay |
US9599626B2 (en) * | 2011-12-01 | 2017-03-21 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Therapeutic and diagnostic method for ataxia-telangiectasia |
US10962553B2 (en) | 2011-12-01 | 2021-03-30 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions and methods for detecting proteinopathies |
US20150065466A1 (en) * | 2012-04-20 | 2015-03-05 | Baylor College Of Medicine | Novel dxr inhibitors for antimicrobial therapy |
CN102793694B (zh) * | 2012-08-14 | 2014-06-04 | 武汉华纳联合药业有限公司 | 3-氨基-1-丙烷磺酸及其衍生物在制备治疗脑卒中的药物中的应用 |
JP5804463B2 (ja) * | 2012-12-27 | 2015-11-04 | 国立研究開発法人科学技術振興機構 | 環状ペプチド及びこれを含有する医薬 |
CN114805211A (zh) | 2017-03-21 | 2022-07-29 | 润佳(苏州)医药科技有限公司 | 同位素富集3-氨基-1-丙磺酸衍生物、药物组合物及其用途 |
WO2018193999A1 (ja) * | 2017-04-17 | 2018-10-25 | 国立大学法人京都大学 | 光学活性な2-アミノ-ホスホノアルカン酸、光学活性な2-アミノ-ホスホノアルカン酸塩、及びこれらの水和物 |
RU2696684C1 (ru) * | 2018-09-18 | 2019-08-05 | Федеральное государственное бюджетное научное учреждение "Научный центр неврологии" (ФГБНУ НЦН) | Способ определения типов когнитивных расстройств у больных церебральной микроангиопатией |
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BR0016652A (pt) * | 1999-12-23 | 2002-11-19 | Neurochem Inc | Métodos para inibir angiopatia amilóide cerebral, para tratar um estado de doença caracterizado por angiopatia amilóide cerebral em um indivìduo, e para diagnosticar angiopatia amilóide cerebral em um indivìduo |
-
2000
- 2000-12-22 BR BR0016652-9A patent/BR0016652A/pt not_active Application Discontinuation
- 2000-12-22 JP JP2001581748A patent/JP2003532656A/ja active Pending
- 2000-12-22 KR KR1020077030145A patent/KR20080003945A/ko not_active Application Discontinuation
- 2000-12-22 MX MXPA02006196A patent/MXPA02006196A/es not_active Application Discontinuation
- 2000-12-22 EP EP00993855A patent/EP1251837A2/en not_active Withdrawn
- 2000-12-22 AU AU84313/01A patent/AU8431301A/en not_active Abandoned
- 2000-12-22 KR KR1020027008226A patent/KR20020063266A/ko not_active Application Discontinuation
- 2000-12-22 KR KR1020097001295A patent/KR20090016517A/ko active Search and Examination
- 2000-12-22 CA CA002395314A patent/CA2395314A1/en not_active Abandoned
- 2000-12-22 CN CN00819104A patent/CN1434706A/zh active Pending
- 2000-12-22 US US09/747,408 patent/US6670399B2/en not_active Expired - Fee Related
- 2000-12-22 IL IL15037400A patent/IL150374A0/xx unknown
- 2000-12-22 WO PCT/IB2000/002078 patent/WO2001085093A2/en not_active Application Discontinuation
-
2003
- 2003-11-10 US US10/705,028 patent/US20080317834A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1251837A2 (en) | 2002-10-30 |
JP2003532656A (ja) | 2003-11-05 |
IL150374A0 (en) | 2002-12-01 |
MXPA02006196A (es) | 2002-12-09 |
KR20080003945A (ko) | 2008-01-08 |
US6670399B2 (en) | 2003-12-30 |
CN1434706A (zh) | 2003-08-06 |
CA2395314A1 (en) | 2001-11-15 |
KR20020063266A (ko) | 2002-08-01 |
US20030003141A1 (en) | 2003-01-02 |
US20080317834A1 (en) | 2008-12-25 |
WO2001085093A2 (en) | 2001-11-15 |
WO2001085093A9 (en) | 2002-09-26 |
KR20090016517A (ko) | 2009-02-13 |
WO2001085093A3 (en) | 2002-08-29 |
AU8431301A (en) | 2001-11-20 |
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