HU230576B1 - Kiméra fertőző DNS-klónok, kiméra sertés cirkovírusok, és alkalmazásuk - Google Patents

Kiméra fertőző DNS-klónok, kiméra sertés cirkovírusok, és alkalmazásuk Download PDF

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Publication number
HU230576B1
HU230576B1 HU1300097A HUP1300097A HU230576B1 HU 230576 B1 HU230576 B1 HU 230576B1 HU 1300097 A HU1300097 A HU 1300097A HU P1300097 A HUP1300097 A HU P1300097A HU 230576 B1 HU230576 B1 HU 230576B1
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Hungary
Prior art keywords
pcv2
pigs
dna
chimeric
vaccine
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HU1300097A
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English (en)
Hungarian (hu)
Inventor
Xiang-Jin Meng
Martijn Fenaux
Patrick G. Halbur
Original Assignee
Iowa State University Research Foundation, Inc.
Virginia Tech Intellectual Properties, Inc.
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Publication date
Application filed by Iowa State University Research Foundation, Inc., Virginia Tech Intellectual Properties, Inc. filed Critical Iowa State University Research Foundation, Inc.
Publication of HUP1300097A2 publication Critical patent/HUP1300097A2/hu
Publication of HU230576B1 publication Critical patent/HU230576B1/hu

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10061—Methods of inactivation or attenuation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HU1300097A 2001-12-12 2002-12-11 Kiméra fertőző DNS-klónok, kiméra sertés cirkovírusok, és alkalmazásuk HU230576B1 (hu)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US34077501P 2001-12-12 2001-12-12
US60/340,775 2001-12-12
US42484002P 2002-11-08 2002-11-08
US60/424,840 2002-11-08
US10/314,512 US7276353B2 (en) 2001-12-12 2002-12-09 Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US10/314,512 2002-12-09
PCT/US2002/039646 WO2003049703A2 (en) 2001-12-12 2002-12-11 Chimeric infectious dna clones, chimeric porcine circoviruses and uses thereof

Publications (2)

Publication Number Publication Date
HUP1300097A2 HUP1300097A2 (en) 2007-12-28
HU230576B1 true HU230576B1 (hu) 2017-01-30

Family

ID=27405726

Family Applications (5)

Application Number Title Priority Date Filing Date
HU0501000A HU228584B1 (en) 2001-12-12 2002-12-11 Chimeric infectious dna clones, chimeric porcine circoviruses and uses thereof
HU1300097A HU230576B1 (hu) 2001-12-12 2002-12-11 Kiméra fertőző DNS-klónok, kiméra sertés cirkovírusok, és alkalmazásuk
HU1600373A HU231018B1 (hu) 2001-12-12 2002-12-11 Kiméra fertőző DNS-klónok, kiméra sertés cirkovírusok, és alkalmazásuk
HU1800263A HU231162B1 (hu) 2001-12-12 2002-12-11 Kiméra fertőző DNS-klónok, kiméra sertés cirkovírusok, és alkalmazásuk
HUS2100036C HUS2100036I1 (hu) 2001-12-12 2021-09-14 Kiméra fertõzõ DNS-klónok, kiméra sertés cirkovírusok, és alkalmazásuk

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU0501000A HU228584B1 (en) 2001-12-12 2002-12-11 Chimeric infectious dna clones, chimeric porcine circoviruses and uses thereof

Family Applications After (3)

Application Number Title Priority Date Filing Date
HU1600373A HU231018B1 (hu) 2001-12-12 2002-12-11 Kiméra fertőző DNS-klónok, kiméra sertés cirkovírusok, és alkalmazásuk
HU1800263A HU231162B1 (hu) 2001-12-12 2002-12-11 Kiméra fertőző DNS-klónok, kiméra sertés cirkovírusok, és alkalmazásuk
HUS2100036C HUS2100036I1 (hu) 2001-12-12 2021-09-14 Kiméra fertõzõ DNS-klónok, kiméra sertés cirkovírusok, és alkalmazásuk

Country Status (30)

Country Link
US (1) US7276353B2 (enExample)
EP (5) EP2263689B1 (enExample)
JP (1) JP4623964B2 (enExample)
KR (1) KR101014544B1 (enExample)
CN (2) CN103536911B (enExample)
AT (1) ATE487490T1 (enExample)
AU (3) AU2002362147C1 (enExample)
BE (1) BE2011C008I2 (enExample)
BR (1) BRPI0214919B1 (enExample)
CA (2) CA2469599C (enExample)
CO (1) CO5590938A2 (enExample)
CY (3) CY1111167T1 (enExample)
DE (2) DE60238278D1 (enExample)
DK (3) DK1487483T3 (enExample)
ES (3) ES2694505T3 (enExample)
FR (1) FR11C0014I2 (enExample)
HR (3) HRP20140003B1 (enExample)
HU (5) HU228584B1 (enExample)
LT (1) LT2264050T (enExample)
LU (1) LU91814I2 (enExample)
ME (1) ME00126B (enExample)
MX (1) MXPA04005364A (enExample)
NL (1) NL300480I2 (enExample)
NZ (2) NZ567688A (enExample)
PL (3) PL215058B1 (enExample)
PT (3) PT2263689E (enExample)
RS (1) RS51288B (enExample)
SI (3) SI2263689T1 (enExample)
TW (1) TWI314580B (enExample)
WO (1) WO2003049703A2 (enExample)

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