HU229989B1 - L-karnitin és alkanoil-L-karnitin taurin-kloriddal és glicin-kloriddal alkotott nem higroszkópos sói és ezeket tartalmazó, orális beadásra alkalmas szilárd készítmények - Google Patents
L-karnitin és alkanoil-L-karnitin taurin-kloriddal és glicin-kloriddal alkotott nem higroszkópos sói és ezeket tartalmazó, orális beadásra alkalmas szilárd készítményekInfo
- Publication number
- HU229989B1 HU229989B1 HU0302294A HUP0302294A HU229989B1 HU 229989 B1 HU229989 B1 HU 229989B1 HU 0302294 A HU0302294 A HU 0302294A HU P0302294 A HUP0302294 A HU P0302294A HU 229989 B1 HU229989 B1 HU 229989B1
- Authority
- HU
- Hungary
- Prior art keywords
- chloride
- carnitine
- alkanoyl
- solid compositions
- oral administration
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 4
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 title abstract 4
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical class C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 3
- -1 alkanoyl l-carnitines Chemical class 0.000 title abstract 3
- 239000008247 solid mixture Substances 0.000 title abstract 3
- WCBVOPMSONYWEB-UHFFFAOYSA-N 2-aminoacetyl chloride Chemical compound NCC(Cl)=O WCBVOPMSONYWEB-UHFFFAOYSA-N 0.000 title abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 title abstract 2
- 229960003080 taurine Drugs 0.000 title abstract 2
- 229960001518 levocarnitine Drugs 0.000 title 1
- MVVVMGRRDIXCLD-UHFFFAOYSA-N 2-aminoethanesulfonyl chloride Chemical compound NCCS(Cl)(=O)=O MVVVMGRRDIXCLD-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/24—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
- A23L33/22—Comminuted fibrous parts of plants, e.g. bagasse or pulp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Botany (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000RM000567A IT1317924B1 (it) | 2000-10-31 | 2000-10-31 | Composizioni solide atte alla somministrazione orale comprendenti salinon igroscopici della l-carnitina e delle alcanoil l-carnitine con |
| PCT/IT2001/000503 WO2002036543A1 (en) | 2000-10-31 | 2001-09-28 | Solid compositions suitable for oral administration containing non-hygroscopic salts of l-carnitine and the alkanoyl l-carnitines with taurine chloride and glycine chloride |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HUP0302294A2 HUP0302294A2 (hu) | 2003-10-28 |
| HUP0302294A3 HUP0302294A3 (en) | 2005-05-30 |
| HU229989B1 true HU229989B1 (hu) | 2015-04-28 |
Family
ID=11454973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0302294A HU229989B1 (hu) | 2000-10-31 | 2001-09-28 | L-karnitin és alkanoil-L-karnitin taurin-kloriddal és glicin-kloriddal alkotott nem higroszkópos sói és ezeket tartalmazó, orális beadásra alkalmas szilárd készítmények |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7858820B2 (hu) |
| EP (1) | EP1330428B1 (hu) |
| JP (1) | JP4181406B2 (hu) |
| KR (1) | KR100764155B1 (hu) |
| CN (1) | CN1219748C (hu) |
| AT (1) | ATE312810T1 (hu) |
| AU (2) | AU9589301A (hu) |
| BR (1) | BRPI0115019B1 (hu) |
| CA (1) | CA2427482C (hu) |
| CY (1) | CY1106062T1 (hu) |
| CZ (1) | CZ302802B6 (hu) |
| DE (1) | DE60115944T2 (hu) |
| DK (1) | DK1330428T3 (hu) |
| ES (1) | ES2253430T3 (hu) |
| HK (1) | HK1061230A1 (hu) |
| HU (1) | HU229989B1 (hu) |
| IT (1) | IT1317924B1 (hu) |
| MX (1) | MXPA03003799A (hu) |
| NZ (1) | NZ525333A (hu) |
| PL (1) | PL205801B1 (hu) |
| RU (1) | RU2270191C2 (hu) |
| SI (1) | SI1330428T1 (hu) |
| SK (1) | SK287133B6 (hu) |
| WO (1) | WO2002036543A1 (hu) |
| ZA (1) | ZA200303328B (hu) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005031705A1 (de) * | 2005-07-05 | 2007-01-18 | Henkel Kgaa | Mittel, enthaltend L-Carnitin oder L-Carnitinderivate und mindestens eine weitere Substanz ausgewählt aus Taurin und dessen Derivaten und mindestens einem Wirkstoff, erhältlich aus Pflanzen der Gattung Echinacea |
| KR101007927B1 (ko) | 2008-12-24 | 2011-01-14 | 주식회사 셀트리온제약 | 시부트라민-ｌ-카르니틴 다이술폰산염, 이의 제조방법 및 이를 포함하는 약제학적 조성물 |
| JP5451558B2 (ja) * | 2010-08-27 | 2014-03-26 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ | 美容活性成分の送達に有用なゲル |
| CN104276986B (zh) * | 2013-07-12 | 2016-07-06 | 辽宁科硕营养科技有限公司 | 左旋肉碱牛磺酸盐的制备方法 |
| JP6473352B2 (ja) * | 2015-03-10 | 2019-02-20 | 利幸 糸井 | 虚血性疾患治療薬 |
| CN107325013B (zh) * | 2016-04-28 | 2019-04-12 | 辽宁科硕营养科技股份有限公司 | 一种合成甘氨酸丙酰左旋肉碱盐酸盐的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3463261D1 (en) | 1983-12-28 | 1987-05-27 | Sigma Tau Ind Farmaceuti | Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same |
| CA2030310A1 (en) * | 1989-12-22 | 1991-06-23 | Ronald E. Macleay | Derivatives of n-hals-substituted amic acid hydrazides |
| IT1291126B1 (it) * | 1997-04-01 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizioni solide atte alla somministrazione orale comprendenti sali non igroscopici della l-carnitina e delle alcanoil l-carnitine |
| IT1306147B1 (it) * | 1999-05-28 | 2001-05-30 | Biosalts Srl | Derivati di principi attivi ad attivita' terapeutica e/o nutrizionalee composizioni atte alla somministrazione orale contenenti tali |
-
2000
- 2000-10-31 IT IT2000RM000567A patent/IT1317924B1/it active
-
2001
- 2001-09-28 CA CA2427482A patent/CA2427482C/en not_active Expired - Fee Related
- 2001-09-28 JP JP2002539304A patent/JP4181406B2/ja not_active Expired - Fee Related
- 2001-09-28 MX MXPA03003799A patent/MXPA03003799A/es active IP Right Grant
- 2001-09-28 EP EP01976633A patent/EP1330428B1/en not_active Expired - Lifetime
- 2001-09-28 WO PCT/IT2001/000503 patent/WO2002036543A1/en active IP Right Grant
- 2001-09-28 DK DK01976633T patent/DK1330428T3/da active
- 2001-09-28 BR BRPI0115019A patent/BRPI0115019B1/pt not_active IP Right Cessation
- 2001-09-28 HU HU0302294A patent/HU229989B1/hu not_active IP Right Cessation
- 2001-09-28 SK SK501-2003A patent/SK287133B6/sk not_active IP Right Cessation
- 2001-09-28 ES ES01976633T patent/ES2253430T3/es not_active Expired - Lifetime
- 2001-09-28 KR KR1020037005596A patent/KR100764155B1/ko active IP Right Grant
- 2001-09-28 RU RU2003116133/04A patent/RU2270191C2/ru active
- 2001-09-28 US US10/415,472 patent/US7858820B2/en not_active Expired - Lifetime
- 2001-09-28 AU AU9589301A patent/AU9589301A/xx active Pending
- 2001-09-28 DE DE60115944T patent/DE60115944T2/de not_active Expired - Lifetime
- 2001-09-28 AU AU2001295893A patent/AU2001295893B2/en not_active Ceased
- 2001-09-28 CZ CZ20031041A patent/CZ302802B6/cs not_active IP Right Cessation
- 2001-09-28 CN CNB018182941A patent/CN1219748C/zh not_active Expired - Lifetime
- 2001-09-28 SI SI200130462T patent/SI1330428T1/sl unknown
- 2001-09-28 PL PL364823A patent/PL205801B1/pl unknown
- 2001-09-28 AT AT01976633T patent/ATE312810T1/de active
- 2001-09-28 NZ NZ525333A patent/NZ525333A/en not_active IP Right Cessation
-
2003
- 2003-04-30 ZA ZA200303328A patent/ZA200303328B/en unknown
-
2004
- 2004-06-16 HK HK04104342A patent/HK1061230A1/xx not_active IP Right Cessation
-
2006
- 2006-01-19 CY CY20061100074T patent/CY1106062T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1112139T1 (el) | Μια φαρμακευτικη συνθεση περιλαμβανουσα κρυσταλλικη ριτοναβιρη μορφη ιι και ενα παρασκευασμα εξ αυτης | |
| WO1996017587A3 (en) | Oral compositions containing stabilized stannous compounds | |
| MX9504034A (es) | Formas de administracion medicamentosas que contienen acido tioctico, o sales solidas del acido tioctico de liberacion y biodisponibilidad mejoradas. | |
| BR9705484A (pt) | Composições de zinco com sabor para uso oral incorporando cobre | |
| AU2001291173A1 (en) | Gamma-hydroxybutyrate compositions containing carbohydrate, lipid or amino acid carriers | |
| HK1046374A1 (en) | Camptothecin analogs and methods of preparation thereof | |
| ES2183595T3 (es) | Empleo de ectoina o derivados de ectoina en formulaciones. | |
| NO20034863L (no) | Deutererte 3-piperidinopropiofenon så vel som legemidler som inneholder disse forbindelser | |
| PT1051159E (pt) | Composicoes farmaceuticas solidas contendo miltefosina para administracao oral no tratamento de leishmaniose | |
| AU9589301A (en) | Solid compositions suitable for oral administration containing non-hygroscopic salts of l-carnitine and the alkanoyl l-carnitines with taurine chloride and glycine chloride | |
| YU95302A (sh) | Stabilni gabapentin koji ima ph u kontrolisanom rasponu | |
| BR9915692A (pt) | Monohidrato de bromidrato de eletriptano | |
| RS63804A (en) | Stable salts of o-acetylsalicylic acid containing basic amino acids ii | |
| CA2344686A1 (en) | High purity composition comprising (7.alpha.,17.alpha.)-17-hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn-3-one | |
| PL367812A1 (en) | Alpha-ketoglutarates of active ingredients and compositions containing same | |
| IL140487A0 (en) | Solid compositions suitable for oral administration containing non-hygroscopic salts of l-carnitine and alkanoyl l-carnitines | |
| HK1047084A1 (en) | Therapeutically and/or nutritionally enhanced derivatives of active ingredients and orally administrable compositions containing same. | |
| HK1049326B (zh) | 具有治療和/或營養活性的活性成分的不吸濕的鹽以及含有它們的可口服的組合物 | |
| ES2167878T3 (es) | Composiciones solidas apropiadas para administracion oral que comprenden sales no higroscopicas de l-carnitina y alcanoil-l-carnitina con acido 2-aminoetansulfonico. | |
| AR008764A1 (es) | Sales hidratadas de n,n'-diacetilcistina, proceso para su preparacion, y composiciones terapeuticas que comprenden a dichas sales como ingredienteactivo. | |
| IL71068A (en) | N-(3-trifluoromethylphenyl)-n'-propargyl-piperazine,its preparation and pharmaceutical compositions containing it |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB9A | Succession in title |
Owner name: ALFASIGMA S.P.A., IT Free format text: FORMER OWNER(S): SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A., IT |
|
| MM4A | Lapse of definitive patent protection due to non-payment of fees |