HUP0302294A2 - L-karnitin és alkanoil-L-karnitin taurin-kloriddal és glicin-kloriddal alkotott nem higroszkópos sói és ezeket tartalmazó, orális beadásra alkalmas szilárd készítmények - Google Patents

L-karnitin és alkanoil-L-karnitin taurin-kloriddal és glicin-kloriddal alkotott nem higroszkópos sói és ezeket tartalmazó, orális beadásra alkalmas szilárd készítmények

Info

Publication number
HUP0302294A2
HUP0302294A2 HU0302294A HUP0302294A HUP0302294A2 HU P0302294 A2 HUP0302294 A2 HU P0302294A2 HU 0302294 A HU0302294 A HU 0302294A HU P0302294 A HUP0302294 A HU P0302294A HU P0302294 A2 HUP0302294 A2 HU P0302294A2
Authority
HU
Hungary
Prior art keywords
chloride
carnitine
alkanoyl
oral administration
carnitines
Prior art date
Application number
HU0302294A
Other languages
English (en)
Inventor
Maria Ornella Tinti
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of HUP0302294A2 publication Critical patent/HUP0302294A2/hu
Publication of HUP0302294A3 publication Critical patent/HUP0302294A3/hu
Publication of HU229989B1 publication Critical patent/HU229989B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/24—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A23L33/22—Comminuted fibrous parts of plants, e.g. bagasse or pulp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Neurology (AREA)
  • Mycology (AREA)
  • Obesity (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

A találmány L-karnitin és alkanoil-L-karnitin taurin-kloriddal ésglicin-kloriddal alkotott fiziológiailag elfogadható sóira vonatkozik,melyekre az jellemző, hogy nem higroszkóposak és stabilak. Az említettsók kedvezőek orális beadásra alkalmas szilárd készítményekelőállításánál. A találmány továbbá ilyen sókat tartalmazó gyógyászatiés táplálkozási vagy nutricionális készítményekre vonatkozik. Ó
HU0302294A 2000-10-31 2001-09-28 L-karnitin és alkanoil-L-karnitin taurin-kloriddal és glicin-kloriddal alkotott nem higroszkópos sói és ezeket tartalmazó, orális beadásra alkalmas szilárd készítmények HU229989B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000RM000567A IT1317924B1 (it) 2000-10-31 2000-10-31 Composizioni solide atte alla somministrazione orale comprendenti salinon igroscopici della l-carnitina e delle alcanoil l-carnitine con
PCT/IT2001/000503 WO2002036543A1 (en) 2000-10-31 2001-09-28 Solid compositions suitable for oral administration containing non-hygroscopic salts of l-carnitine and the alkanoyl l-carnitines with taurine chloride and glycine chloride

Publications (3)

Publication Number Publication Date
HUP0302294A2 true HUP0302294A2 (hu) 2003-10-28
HUP0302294A3 HUP0302294A3 (en) 2005-05-30
HU229989B1 HU229989B1 (hu) 2015-04-28

Family

ID=11454973

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0302294A HU229989B1 (hu) 2000-10-31 2001-09-28 L-karnitin és alkanoil-L-karnitin taurin-kloriddal és glicin-kloriddal alkotott nem higroszkópos sói és ezeket tartalmazó, orális beadásra alkalmas szilárd készítmények

Country Status (25)

Country Link
US (1) US7858820B2 (hu)
EP (1) EP1330428B1 (hu)
JP (1) JP4181406B2 (hu)
KR (1) KR100764155B1 (hu)
CN (1) CN1219748C (hu)
AT (1) ATE312810T1 (hu)
AU (2) AU9589301A (hu)
BR (1) BRPI0115019B1 (hu)
CA (1) CA2427482C (hu)
CY (1) CY1106062T1 (hu)
CZ (1) CZ302802B6 (hu)
DE (1) DE60115944T2 (hu)
DK (1) DK1330428T3 (hu)
ES (1) ES2253430T3 (hu)
HK (1) HK1061230A1 (hu)
HU (1) HU229989B1 (hu)
IT (1) IT1317924B1 (hu)
MX (1) MXPA03003799A (hu)
NZ (1) NZ525333A (hu)
PL (1) PL205801B1 (hu)
RU (1) RU2270191C2 (hu)
SI (1) SI1330428T1 (hu)
SK (1) SK287133B6 (hu)
WO (1) WO2002036543A1 (hu)
ZA (1) ZA200303328B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005031705A1 (de) * 2005-07-05 2007-01-18 Henkel Kgaa Mittel, enthaltend L-Carnitin oder L-Carnitinderivate und mindestens eine weitere Substanz ausgewählt aus Taurin und dessen Derivaten und mindestens einem Wirkstoff, erhältlich aus Pflanzen der Gattung Echinacea
KR101007927B1 (ko) 2008-12-24 2011-01-14 주식회사 셀트리온제약 시부트라민-ｌ-카르니틴 다이술폰산염, 이의 제조방법 및 이를 포함하는 약제학적 조성물
JP5451558B2 (ja) * 2010-08-27 2014-03-26 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ 美容活性成分の送達に有用なゲル
CN104276986B (zh) * 2013-07-12 2016-07-06 辽宁科硕营养科技有限公司 左旋肉碱牛磺酸盐的制备方法
JP6473352B2 (ja) * 2015-03-10 2019-02-20 利幸 糸井 虚血性疾患治療薬
CN107325013B (zh) * 2016-04-28 2019-04-12 辽宁科硕营养科技股份有限公司 一种合成甘氨酸丙酰左旋肉碱盐酸盐的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0150688B1 (en) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
CA2030310A1 (en) * 1989-12-22 1991-06-23 Ronald E. Macleay Derivatives of n-hals-substituted amic acid hydrazides
IT1291126B1 (it) * 1997-04-01 1998-12-29 Sigma Tau Ind Farmaceuti Composizioni solide atte alla somministrazione orale comprendenti sali non igroscopici della l-carnitina e delle alcanoil l-carnitine
IT1306147B1 (it) * 1999-05-28 2001-05-30 Biosalts Srl Derivati di principi attivi ad attivita' terapeutica e/o nutrizionalee composizioni atte alla somministrazione orale contenenti tali

Also Published As

Publication number Publication date
BR0115019A (pt) 2003-12-23
ITRM20000567A0 (it) 2000-10-31
DK1330428T3 (da) 2006-04-18
AU9589301A (en) 2002-05-15
US20040024061A1 (en) 2004-02-05
CZ20031041A3 (cs) 2003-08-13
MXPA03003799A (es) 2004-04-20
EP1330428B1 (en) 2005-12-14
BRPI0115019B1 (pt) 2015-10-06
CZ302802B6 (cs) 2011-11-16
CY1106062T1 (el) 2011-06-08
PL205801B1 (pl) 2010-05-31
US7858820B2 (en) 2010-12-28
NZ525333A (en) 2004-06-25
JP2004513107A (ja) 2004-04-30
KR100764155B1 (ko) 2007-10-08
ZA200303328B (en) 2004-03-09
CN1473144A (zh) 2004-02-04
RU2270191C2 (ru) 2006-02-20
KR20030059211A (ko) 2003-07-07
ITRM20000567A1 (it) 2002-05-01
SK5012003A3 (en) 2003-11-04
DE60115944D1 (de) 2006-01-19
PL364823A1 (en) 2004-12-27
HUP0302294A3 (en) 2005-05-30
ES2253430T3 (es) 2006-06-01
CA2427482A1 (en) 2002-05-10
WO2002036543A1 (en) 2002-05-10
EP1330428A1 (en) 2003-07-30
JP4181406B2 (ja) 2008-11-12
SI1330428T1 (sl) 2006-04-30
DE60115944T2 (de) 2006-06-29
HU229989B1 (hu) 2015-04-28
IT1317924B1 (it) 2003-07-15
HK1061230A1 (en) 2004-09-10
CA2427482C (en) 2010-04-27
CN1219748C (zh) 2005-09-21
ATE312810T1 (de) 2005-12-15
AU2001295893B2 (en) 2006-11-30
SK287133B6 (sk) 2010-01-07

Similar Documents

Publication Publication Date Title
CY1111470T1 (el) Νεες φαρμακευτικες συνθεσεις που περιεχουν φλιβανσερινη πολυμορφη α
NO20034863L (no) Deutererte 3-piperidinopropiofenon så vel som legemidler som inneholder disse forbindelser
CY1107349T1 (el) Αλφα-κετογλουταρικα ενεργα συστατικα και σκευασματα που τα περιεχουν
HUP0002198A2 (hu) L-Karnitin- vagy alkanoil-L-karnitin-magnézium-fumarátot tartalmazó orálisan beadható szilárd készítmények
HUP0302294A2 (hu) L-karnitin és alkanoil-L-karnitin taurin-kloriddal és glicin-kloriddal alkotott nem higroszkópos sói és ezeket tartalmazó, orális beadásra alkalmas szilárd készítmények
ES2190069T3 (es) Composiciones solidas apropiadas para la administracion por via oral que contienen un citrato de magnesio de alcanoilo-l-carnitina.
WO2003049687A3 (en) Medicinal compositions & therapeutic methods
DK1202956T3 (da) Terapeutisk og/eller ernærngsmæssigt forstærkede derivater af aktive bestanddele og oralt indgivelsesbare præparater indeholdende de samme
PT971879E (pt) Composicoes solidas adequadas para administracao oral compreendendo l-carnitino e alcanoil.l.carnitino tartarato de magnesio
DK1289931T3 (da) Dobbeltsalte af fumarsyre med et carnitin og en aminosyre samt kosttilskud, diættilskud og lægemidler indeholdende samme
BR9808908A (pt) Composições sólidas adequadas para administração oral que compreendem l-carnitina ou tartarato de alcanoil-l-carnitina colina
BR9808461A (pt) Método para composições sólidas adequadas para administração oral compreendendo sais não higroscópicos de l-carnitina e alcanoil-l-carnitina com ácido 2-aminoetassulfÈnico.
HK1049326B (zh) 具有治療和/或營養活性的活性成分的不吸濕的鹽以及含有它們的可口服的組合物
DE69911021D1 (de) Nicht-hygroskopische salze des l-karnitines und der alkanoyl-karnitine enthaltende feste zusammensetzungen zur oralen verabreichung

Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: ALFASIGMA S.P.A., IT

Free format text: FORMER OWNER(S): SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A., IT

MM4A Lapse of definitive patent protection due to non-payment of fees