CY1106062T1 - Στepεες συνθεσεις που ειναι καταλληλες για εκ του στοματος χορηγηση που πepιεχουν μη-υγροσκοπικα αλατα της l-καρνιτινης και των αλκανοϋλ l-καρνιτινων με χλωριουχο ταυρινη - Google Patents

Στepεες συνθεσεις που ειναι καταλληλες για εκ του στοματος χορηγηση που πepιεχουν μη-υγροσκοπικα αλατα της l-καρνιτινης και των αλκανοϋλ l-καρνιτινων με χλωριουχο ταυρινη

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Publication number
CY1106062T1
CY1106062T1 CY20061100074T CY061100074T CY1106062T1 CY 1106062 T1 CY1106062 T1 CY 1106062T1 CY 20061100074 T CY20061100074 T CY 20061100074T CY 061100074 T CY061100074 T CY 061100074T CY 1106062 T1 CY1106062 T1 CY 1106062T1
Authority
CY
Cyprus
Prior art keywords
carnitine
alkanoyl
solid compositions
oral administration
carnitines
Prior art date
Application number
CY20061100074T
Other languages
English (en)
Inventor
Maria Ornella Tinti
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of CY1106062T1 publication Critical patent/CY1106062T1/el

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/24Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • A23L33/22Comminuted fibrous parts of plants, e.g. bagasse or pulp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
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    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Chemical & Material Sciences (AREA)
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  • Public Health (AREA)
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  • Obesity (AREA)
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  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Περιγράφονται εις το παρόν συνημμένο αμφότερα τα μη-υγροσκοπικά άλατα της L-καρνιτίνης και της αλκανοϋλ L-καρνιτίνης με χλωριούχο ταυρίνη (χλωριούχο σουλφονικό 2-αμινοαιθάνιο) και τα μη-υγροσκοπικά άλατα της L-καρνιτίνης και της αλκανοϋλ L-καρνιτίνης με χλωριούχο γλυκίνη τα οποία προσέφεραν αυτά τα ίδια κατά ευνοϊκό τρόπο στην παρασκευή στερεών συνθέσεων που είναι κατάλληλες για εκ του στόματος χορήγηση. Επίσης περιγράφονται οι στερεές συνθέσεις που περιέχουν τα εν λόγω άλατα.
CY20061100074T 2000-10-31 2006-01-19 Στepεες συνθεσεις που ειναι καταλληλες για εκ του στοματος χορηγηση που πepιεχουν μη-υγροσκοπικα αλατα της l-καρνιτινης και των αλκανοϋλ l-καρνιτινων με χλωριουχο ταυρινη CY1106062T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000RM000567A IT1317924B1 (it) 2000-10-31 2000-10-31 Composizioni solide atte alla somministrazione orale comprendenti salinon igroscopici della l-carnitina e delle alcanoil l-carnitine con
PCT/IT2001/000503 WO2002036543A1 (en) 2000-10-31 2001-09-28 Solid compositions suitable for oral administration containing non-hygroscopic salts of l-carnitine and the alkanoyl l-carnitines with taurine chloride and glycine chloride

Publications (1)

Publication Number Publication Date
CY1106062T1 true CY1106062T1 (el) 2011-06-08

Family

ID=11454973

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061100074T CY1106062T1 (el) 2000-10-31 2006-01-19 Στepεες συνθεσεις που ειναι καταλληλες για εκ του στοματος χορηγηση που πepιεχουν μη-υγροσκοπικα αλατα της l-καρνιτινης και των αλκανοϋλ l-καρνιτινων με χλωριουχο ταυρινη

Country Status (25)

Country Link
US (1) US7858820B2 (el)
EP (1) EP1330428B1 (el)
JP (1) JP4181406B2 (el)
KR (1) KR100764155B1 (el)
CN (1) CN1219748C (el)
AT (1) ATE312810T1 (el)
AU (2) AU9589301A (el)
BR (1) BRPI0115019B1 (el)
CA (1) CA2427482C (el)
CY (1) CY1106062T1 (el)
CZ (1) CZ302802B6 (el)
DE (1) DE60115944T2 (el)
DK (1) DK1330428T3 (el)
ES (1) ES2253430T3 (el)
HK (1) HK1061230A1 (el)
HU (1) HU229989B1 (el)
IT (1) IT1317924B1 (el)
MX (1) MXPA03003799A (el)
NZ (1) NZ525333A (el)
PL (1) PL205801B1 (el)
RU (1) RU2270191C2 (el)
SI (1) SI1330428T1 (el)
SK (1) SK287133B6 (el)
WO (1) WO2002036543A1 (el)
ZA (1) ZA200303328B (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005031705A1 (de) * 2005-07-05 2007-01-18 Henkel Kgaa Mittel, enthaltend L-Carnitin oder L-Carnitinderivate und mindestens eine weitere Substanz ausgewählt aus Taurin und dessen Derivaten und mindestens einem Wirkstoff, erhältlich aus Pflanzen der Gattung Echinacea
KR101007927B1 (ko) 2008-12-24 2011-01-14 주식회사 셀트리온제약 시부트라민-l-카르니틴 다이술폰산염, 이의 제조방법 및 이를 포함하는 약제학적 조성물
JP5451558B2 (ja) * 2010-08-27 2014-03-26 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ 美容活性成分の送達に有用なゲル
CN104276986B (zh) * 2013-07-12 2016-07-06 辽宁科硕营养科技有限公司 左旋肉碱牛磺酸盐的制备方法
JP6473352B2 (ja) * 2015-03-10 2019-02-20 利幸 糸井 虚血性疾患治療薬
CN107325013B (zh) * 2016-04-28 2019-04-12 辽宁科硕营养科技股份有限公司 一种合成甘氨酸丙酰左旋肉碱盐酸盐的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0150688B1 (en) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
CA2030310A1 (en) * 1989-12-22 1991-06-23 Ronald E. Macleay Derivatives of n-hals-substituted amic acid hydrazides
IT1291126B1 (it) * 1997-04-01 1998-12-29 Sigma Tau Ind Farmaceuti Composizioni solide atte alla somministrazione orale comprendenti sali non igroscopici della l-carnitina e delle alcanoil l-carnitine
IT1306147B1 (it) * 1999-05-28 2001-05-30 Biosalts Srl Derivati di principi attivi ad attivita' terapeutica e/o nutrizionalee composizioni atte alla somministrazione orale contenenti tali

Also Published As

Publication number Publication date
BR0115019A (pt) 2003-12-23
ITRM20000567A0 (it) 2000-10-31
DK1330428T3 (da) 2006-04-18
AU9589301A (en) 2002-05-15
US20040024061A1 (en) 2004-02-05
CZ20031041A3 (cs) 2003-08-13
MXPA03003799A (es) 2004-04-20
EP1330428B1 (en) 2005-12-14
BRPI0115019B1 (pt) 2015-10-06
CZ302802B6 (cs) 2011-11-16
PL205801B1 (pl) 2010-05-31
US7858820B2 (en) 2010-12-28
NZ525333A (en) 2004-06-25
JP2004513107A (ja) 2004-04-30
KR100764155B1 (ko) 2007-10-08
ZA200303328B (en) 2004-03-09
CN1473144A (zh) 2004-02-04
RU2270191C2 (ru) 2006-02-20
KR20030059211A (ko) 2003-07-07
ITRM20000567A1 (it) 2002-05-01
SK5012003A3 (en) 2003-11-04
DE60115944D1 (de) 2006-01-19
PL364823A1 (en) 2004-12-27
HUP0302294A2 (hu) 2003-10-28
HUP0302294A3 (en) 2005-05-30
ES2253430T3 (es) 2006-06-01
CA2427482A1 (en) 2002-05-10
WO2002036543A1 (en) 2002-05-10
EP1330428A1 (en) 2003-07-30
JP4181406B2 (ja) 2008-11-12
SI1330428T1 (sl) 2006-04-30
DE60115944T2 (de) 2006-06-29
HU229989B1 (hu) 2015-04-28
IT1317924B1 (it) 2003-07-15
HK1061230A1 (en) 2004-09-10
CA2427482C (en) 2010-04-27
CN1219748C (zh) 2005-09-21
ATE312810T1 (de) 2005-12-15
AU2001295893B2 (en) 2006-11-30
SK287133B6 (sk) 2010-01-07

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