HU229805B1 - Photochemical internalization for delivery of molecules into the cytosol - Google Patents

Photochemical internalization for delivery of molecules into the cytosol Download PDF

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Publication number
HU229805B1
HU229805B1 HU0402260A HUP0402260A HU229805B1 HU 229805 B1 HU229805 B1 HU 229805B1 HU 0402260 A HU0402260 A HU 0402260A HU P0402260 A HUP0402260 A HU P0402260A HU 229805 B1 HU229805 B1 HU 229805B1
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HU
Hungary
Prior art keywords
cells
molecule
cell
agent
irradiation
Prior art date
Application number
HU0402260A
Other languages
English (en)
Hungarian (hu)
Inventor
Kristian Berg
Lina Prasmickaite
Anders Hogset
Pal Kristian Selbo
Original Assignee
Pci Biotech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0029134A external-priority patent/GB0029134D0/en
Priority claimed from GB0029404A external-priority patent/GB0029404D0/en
Priority claimed from GB0114695A external-priority patent/GB0114695D0/en
Application filed by Pci Biotech As filed Critical Pci Biotech As
Publication of HUP0402260A2 publication Critical patent/HUP0402260A2/hu
Publication of HUP0402260A3 publication Critical patent/HUP0402260A3/hu
Publication of HU229805B1 publication Critical patent/HU229805B1/hu

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5156—Animal cells expressing foreign proteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU0402260A 2000-11-29 2001-11-29 Photochemical internalization for delivery of molecules into the cytosol HU229805B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0029134A GB0029134D0 (en) 2000-11-29 2000-11-29 Method
GB0029404A GB0029404D0 (en) 2000-12-01 2000-12-01 Method
GB0114695A GB0114695D0 (en) 2001-06-15 2001-06-15 Method
PCT/GB2001/005299 WO2002044396A1 (en) 2000-11-29 2001-11-29 Photochemical internalization for delivery of molecules into the cytosol

Publications (3)

Publication Number Publication Date
HUP0402260A2 HUP0402260A2 (hu) 2005-02-28
HUP0402260A3 HUP0402260A3 (en) 2005-06-28
HU229805B1 true HU229805B1 (en) 2014-07-28

Family

ID=27255991

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0402260A HU229805B1 (en) 2000-11-29 2001-11-29 Photochemical internalization for delivery of molecules into the cytosol

Country Status (14)

Country Link
US (2) US7223600B2 (https=)
EP (1) EP1346059B1 (https=)
JP (1) JP4578770B2 (https=)
KR (2) KR100980153B1 (https=)
CN (1) CN100558903C (https=)
AU (2) AU2085302A (https=)
BR (1) BR0115795A (https=)
CA (1) CA2430087C (https=)
CZ (1) CZ301427B6 (https=)
ES (1) ES2383516T3 (https=)
HU (1) HU229805B1 (https=)
PL (1) PL213560B1 (https=)
PT (1) PT1346059E (https=)
WO (1) WO2002044396A1 (https=)

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GB0415263D0 (en) * 2004-07-07 2004-08-11 Norwegian Radium Hospital Res Method
GB0613753D0 (en) 2006-07-11 2006-08-23 Norwegian Radium Hospital Res Method
EP2099496A2 (en) * 2006-12-08 2009-09-16 Massachusetts Institute of Technology Delivery of nanoparticles and/or agents to cells
RU2339414C1 (ru) * 2007-03-27 2008-11-27 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Способ подавления роста опухолей
US8411669B2 (en) * 2008-04-18 2013-04-02 Cisco Technology, Inc. Distributed transcoding on IP phones with idle DSP channels
GB0811955D0 (en) 2008-06-30 2008-07-30 Pci Biotech As Method
US8808733B2 (en) 2009-03-31 2014-08-19 The Board Of Trustees Of The University Of Arkansas Method of controlled drug release from a liposome carrier
GB0914287D0 (en) 2009-08-14 2009-09-30 Pci Biotech As Compositions
GB0914286D0 (en) 2009-08-14 2009-09-30 Pci Biotech As Method
JP5979385B2 (ja) * 2011-10-07 2016-08-24 国立大学法人鳥取大学 リポソーム複合体
WO2013070872A1 (en) 2011-11-08 2013-05-16 The Board Of Trustees Of The University Of Arkansas Methods and compositions for x-ray induced release from ph sensitive liposomes
CN105101951B (zh) * 2012-10-29 2021-08-03 新加坡科技研究局 一种用于基因-药物治疗的新型试剂
CA2906279A1 (en) * 2013-03-15 2014-09-18 Pci Biotech As A method of generating antigen presenting cells using photochemical internalisation
WO2015024931A1 (en) 2013-08-19 2015-02-26 Moghimi Seyed Moien Peptidic nanodelivery composition targeting two receptors
JP6684215B2 (ja) * 2013-08-28 2020-04-22 ピーシーアイ バイオテック エイエス 予防接種用化合物および免疫化用化合物、ならびに予防接種方法および免疫化方法
WO2015028575A1 (en) * 2013-08-28 2015-03-05 Pci Biotech As Immunisation method by photochemical internalisation
AU2014390262B2 (en) 2014-04-11 2020-11-26 Pci Biotech As Method of treating melanoma
GB201415250D0 (en) * 2014-08-28 2014-10-15 Pci Biotech As Compound and method
EP3185901B1 (en) 2014-08-28 2023-10-04 PCI Biotech AS Compound and method
GB201503776D0 (en) 2015-03-05 2015-04-22 Pci Biotech As Compound and method
WO2018017954A1 (en) * 2016-07-21 2018-01-25 Rutgers, The State University Of New Jersey Antimicrobial cationic systems and methods of use
AU2017342086A1 (en) 2016-10-14 2019-05-09 Pci Biotech As Treatment of cholangiocarcinoma with TPCS-2a induced photochemical internalisation of gemcitabine
KR101911725B1 (ko) * 2017-01-16 2018-12-28 주식회사 코어파마 적색형광단백질을 발현하는 유전자 및 틴 에틸 에티오푸르푸린을 이용한 광역학 치료용 조성물 및 이를 이용한 광역학 치료방법
CN107029236B (zh) * 2017-04-18 2020-04-10 中国医学科学院生物医学工程研究所 一种吲哚菁绿自组装纳米疫苗及制备方法
GB201718631D0 (en) * 2017-11-10 2017-12-27 Pci Biotech As Method
GB201801169D0 (en) 2018-01-24 2018-03-07 Pci Biotech As Method
EP3823668A1 (en) 2018-07-16 2021-05-26 DCPrime B.V. A combination product for use in tumor vaccination
CA3109804A1 (en) 2018-08-16 2020-02-20 The Regents Of The University Of California Chemically and photochemically initiated cell membrane blebbing to induce cell vesicle production, modifications thereof, and uses thereof
AU2020264083A1 (en) 2019-04-25 2021-12-02 Mendus B.V. Methods of tumor vaccination
US20210322471A1 (en) 2020-03-27 2021-10-21 Dcprime B.V. In vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
US12091681B2 (en) 2020-03-27 2024-09-17 Mendus B.V. Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
CN116133679A (zh) 2020-06-30 2023-05-16 门德斯有限公司 白血病衍生细胞在卵巢癌疫苗中的用途
WO2022097068A1 (en) 2020-11-05 2022-05-12 Dcprime B.V. Use of tumor-independent antigens in immunotherapies
AU2022211682A1 (en) 2021-01-22 2023-08-03 Mendus B.V. Methods of tumor vaccination
KR20230157388A (ko) 2021-03-12 2023-11-16 멘두스 비.브이. 백신접종의 방법 및 cd47 차단의 용도
GB202115451D0 (en) 2021-10-27 2021-12-08 Pci Biotech As Method

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Also Published As

Publication number Publication date
CN1553958A (zh) 2004-12-08
CZ301427B6 (cs) 2010-02-24
WO2002044396A1 (en) 2002-06-06
ES2383516T3 (es) 2012-06-21
HUP0402260A2 (hu) 2005-02-28
US7223600B2 (en) 2007-05-29
HK1056573A1 (en) 2004-02-20
AU2002220853B2 (en) 2007-06-28
PL213560B1 (pl) 2013-03-29
CA2430087C (en) 2016-06-28
CA2430087A1 (en) 2002-06-06
JP4578770B2 (ja) 2010-11-10
CZ20031791A3 (cs) 2003-10-15
AU2085302A (en) 2002-06-11
KR20030074632A (ko) 2003-09-19
JP2004520021A (ja) 2004-07-08
HUP0402260A3 (en) 2005-06-28
US20070274953A1 (en) 2007-11-29
KR20080080685A (ko) 2008-09-04
CN100558903C (zh) 2009-11-11
US20050075268A1 (en) 2005-04-07
PL365006A1 (en) 2004-12-27
KR100980153B1 (ko) 2010-09-03
PT1346059E (pt) 2012-06-01
BR0115795A (pt) 2003-08-12
EP1346059A1 (en) 2003-09-24
US8008077B2 (en) 2011-08-30
EP1346059B1 (en) 2012-05-23

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