HU226422B1 - Use of rapamycin derivatives for the preparation of pharmaceutical compositions treating vasculopathies - Google Patents

Use of rapamycin derivatives for the preparation of pharmaceutical compositions treating vasculopathies Download PDF

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Publication number
HU226422B1
HU226422B1 HU0001267A HUP0001267A HU226422B1 HU 226422 B1 HU226422 B1 HU 226422B1 HU 0001267 A HU0001267 A HU 0001267A HU P0001267 A HUP0001267 A HU P0001267A HU 226422 B1 HU226422 B1 HU 226422B1
Authority
HU
Hungary
Prior art keywords
rapamycin
transplanted
compound
formula
hydroxy
Prior art date
Application number
HU0001267A
Other languages
English (en)
Hungarian (hu)
Inventor
Walter Schuler
Hendrik Schuurman
Gisbert Weckbecker
Hans-Guenter Zerwes
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10791127&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HU226422(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HUP0001267A2 publication Critical patent/HUP0001267A2/hu
Publication of HUP0001267A3 publication Critical patent/HUP0001267A3/hu
Publication of HU226422B1 publication Critical patent/HU226422B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
HU0001267A 1996-03-27 1997-03-26 Use of rapamycin derivatives for the preparation of pharmaceutical compositions treating vasculopathies HU226422B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9606452.2A GB9606452D0 (en) 1996-03-27 1996-03-27 Organic compounds
PCT/EP1997/001548 WO1997035575A1 (en) 1996-03-27 1997-03-26 Use of rapamycin derivatives in vasculopathies and xenotransplantation

Publications (3)

Publication Number Publication Date
HUP0001267A2 HUP0001267A2 (hu) 2000-11-28
HUP0001267A3 HUP0001267A3 (en) 2002-01-28
HU226422B1 true HU226422B1 (en) 2008-12-29

Family

ID=10791127

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0001267A HU226422B1 (en) 1996-03-27 1997-03-26 Use of rapamycin derivatives for the preparation of pharmaceutical compositions treating vasculopathies

Country Status (29)

Country Link
US (5) US6384046B1 (enExample)
EP (3) EP0893996B1 (enExample)
JP (2) JP2000507226A (enExample)
KR (2) KR20070083654A (enExample)
CN (1) CN1124135C (enExample)
AT (1) ATE224194T1 (enExample)
AU (1) AU716514B2 (enExample)
BR (1) BR9708358A (enExample)
CA (1) CA2247275C (enExample)
CY (1) CY2404B1 (enExample)
CZ (1) CZ292483B6 (enExample)
DE (1) DE69715611T2 (enExample)
DK (2) DK2008657T3 (enExample)
ES (2) ES2184078T3 (enExample)
GB (1) GB9606452D0 (enExample)
HU (1) HU226422B1 (enExample)
ID (1) ID17195A (enExample)
IL (1) IL125812A (enExample)
MY (1) MY117798A (enExample)
NO (1) NO316667B1 (enExample)
NZ (1) NZ331463A (enExample)
PL (1) PL187732B1 (enExample)
PT (2) PT893996E (enExample)
RU (1) RU2214247C2 (enExample)
SI (1) SI2008657T1 (enExample)
SK (1) SK284343B6 (enExample)
TR (1) TR199801919T2 (enExample)
WO (1) WO1997035575A1 (enExample)
ZA (1) ZA972719B (enExample)

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Also Published As

Publication number Publication date
CZ307098A3 (cs) 1999-01-13
PT893996E (pt) 2002-12-31
AU716514B2 (en) 2000-02-24
CN1214631A (zh) 1999-04-21
HUP0001267A2 (hu) 2000-11-28
CZ292483B6 (cs) 2003-09-17
EP1149581A2 (en) 2001-10-31
ATE224194T1 (de) 2002-10-15
US20120177690A1 (en) 2012-07-12
CA2247275A1 (en) 1997-10-02
DE69715611D1 (de) 2002-10-24
SK284343B6 (sk) 2005-02-04
EP2008657A3 (en) 2009-02-04
HK1018688A1 (en) 1999-12-30
ID17195A (id) 1997-12-11
KR20050038656A (ko) 2005-04-27
BR9708358A (pt) 1999-08-03
MY117798A (en) 2004-08-30
GB9606452D0 (en) 1996-06-05
DK2008657T3 (da) 2013-07-22
PT2008657E (pt) 2013-07-12
KR100836971B1 (ko) 2008-06-10
IL125812A0 (en) 1999-04-11
US6384046B1 (en) 2002-05-07
NZ331463A (en) 2001-10-26
ZA972719B (en) 1998-09-28
DE69715611T2 (de) 2003-05-22
TR199801919T2 (xx) 1999-02-22
WO1997035575A1 (en) 1997-10-02
JP5124431B2 (ja) 2013-01-23
KR20070083654A (ko) 2007-08-24
PL328659A1 (en) 1999-02-15
CY2404B1 (en) 2004-09-10
US20100152105A1 (en) 2010-06-17
EP2008657B1 (en) 2013-04-24
EP2008657A2 (en) 2008-12-31
CA2247275C (en) 2011-10-11
RU2214247C2 (ru) 2003-10-20
HUP0001267A3 (en) 2002-01-28
PL187732B1 (pl) 2004-09-30
NO984340D0 (no) 1998-09-18
EP1149581A3 (en) 2003-12-03
EP0893996B1 (en) 2002-09-18
ES2184078T3 (es) 2003-04-01
EP0893996A1 (en) 1999-02-03
US20140187574A1 (en) 2014-07-03
SK132798A3 (en) 1999-03-12
IL125812A (en) 2001-12-23
ES2421455T3 (es) 2013-09-02
JP2009102349A (ja) 2009-05-14
DK0893996T3 (da) 2002-12-09
SI2008657T1 (sl) 2013-07-31
JP2000507226A (ja) 2000-06-13
AU2291897A (en) 1997-10-17
NO316667B1 (no) 2004-03-29
NO984340L (no) 1998-09-18
CN1124135C (zh) 2003-10-15
US20020127248A1 (en) 2002-09-12

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