HU218146B - Továbbfejlesztett meningokokkusz-poliszacharid-konjugátum vakcina - Google Patents

Továbbfejlesztett meningokokkusz-poliszacharid-konjugátum vakcina Download PDF

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Publication number
HU218146B
HU218146B HU9201966A HU196692A HU218146B HU 218146 B HU218146 B HU 218146B HU 9201966 A HU9201966 A HU 9201966A HU 196692 A HU196692 A HU 196692A HU 218146 B HU218146 B HU 218146B
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HU
Hungary
Prior art keywords
polysaccharide
gbmp
group
conjugate
modified
Prior art date
Application number
HU9201966A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT64480A (en
Inventor
Harold J. Jennings
Francis Michon
Original Assignee
National Research Council Of Canada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Research Council Of Canada filed Critical National Research Council Of Canada
Publication of HUT64480A publication Critical patent/HUT64480A/hu
Publication of HU218146B publication Critical patent/HU218146B/hu

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K16/1232—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
HU9201966A 1989-12-14 1990-12-13 Továbbfejlesztett meningokokkusz-poliszacharid-konjugátum vakcina HU218146B (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44819589A 1989-12-14 1989-12-14
PCT/CA1990/000437 WO1991008772A1 (en) 1989-12-14 1990-12-13 Improved meningococcal polysaccharide conjugate vaccine

Publications (2)

Publication Number Publication Date
HUT64480A HUT64480A (en) 1994-01-28
HU218146B true HU218146B (hu) 2000-06-28

Family

ID=23779371

Family Applications (2)

Application Number Title Priority Date Filing Date
HU9201966A HU218146B (hu) 1989-12-14 1990-12-13 Továbbfejlesztett meningokokkusz-poliszacharid-konjugátum vakcina
HU9201966A HU9201966D0 (en) 1989-12-14 1990-12-13 An improved vaccine of meningococcus-polysaccharide conjunction

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU9201966A HU9201966D0 (en) 1989-12-14 1990-12-13 An improved vaccine of meningococcus-polysaccharide conjunction

Country Status (30)

Country Link
US (3) US5576002A (Direct)
EP (1) EP0504202B1 (Direct)
JP (1) JP2637845B2 (Direct)
KR (1) KR0158436B1 (Direct)
CN (4) CN1049223C (Direct)
AR (1) AR243934A1 (Direct)
AT (1) ATE121947T1 (Direct)
AU (1) AU641715B2 (Direct)
BR (1) BR9007917A (Direct)
CA (1) CA2071811C (Direct)
CZ (1) CZ283530B6 (Direct)
DE (1) DE69019164T2 (Direct)
DK (1) DK0504202T3 (Direct)
ES (1) ES2071288T3 (Direct)
FI (2) FI104539B (Direct)
HR (1) HRP920872A2 (Direct)
HU (2) HU218146B (Direct)
IE (1) IE68414B1 (Direct)
IL (1) IL96676A (Direct)
IN (1) IN171747B (Direct)
NO (2) NO305275B1 (Direct)
NZ (1) NZ236471A (Direct)
PH (1) PH30305A (Direct)
PL (2) PL166035B1 (Direct)
RO (1) RO111416B1 (Direct)
RU (1) RU2105568C1 (Direct)
SI (1) SI20008B (Direct)
WO (1) WO1991008772A1 (Direct)
YU (1) YU24391A (Direct)
ZA (1) ZA9010065B (Direct)

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ATE203167T1 (de) * 1992-09-24 2001-08-15 Brigham & Womens Hospital Gruppe b streptococcus typ ii und typ v polysaccharid-protein konjugate als impfstoffe
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US5700787A (en) * 1994-09-02 1997-12-23 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US5679654A (en) * 1994-09-02 1997-10-21 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US5747287A (en) * 1995-04-28 1998-05-05 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US5811102A (en) 1995-06-07 1998-09-22 National Research Council Of Canada Modified meningococcal polysaccharide conjugate vaccines
US6284884B1 (en) 1995-06-07 2001-09-04 North American Vaccine, Inc. Antigenic group B streptococcus type II and type III polysaccharide fragments having a 2,5-anhydro-D-mannose terminal structure and conjugate vaccine thereof
JP4233113B2 (ja) * 1995-06-07 2009-03-04 グラクソスミスクライン・バイオロジカルス・ソシエテ・アノニム 多糖類抗原−キャリア蛋白接合体および遊離キャリア蛋白を有してなるワクチン
ZA97248B (en) * 1996-01-18 1997-07-18 Rohm & Haas Method for identifying and quantifying polymers utilizing immunoassay techniques
ATE252602T1 (de) 1996-08-27 2003-11-15 Chiron Corp Meningokokkus b-epitop ausbildende monoklonale antikoerper und deren verwendung zur herstellung von impfstoffzusammenstellungen
PT939647E (pt) 1996-08-27 2002-04-29 Chiron Corp Glicpconjugados do serogrupo b de neisseria meningitidis e metodos de utilizacao dos mesmos
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WO1998058670A1 (en) 1997-06-24 1998-12-30 Chiron Corporation Methods of immunizing adults using anti-meningococcal vaccine compositions
PT1630168E (pt) * 1997-08-27 2011-07-20 Novartis Vaccines & Diagnostic Compostos miméticos moleculares de péptidos de meningococos do serogrupo b
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HUP0103100A3 (en) * 1998-08-19 2005-11-28 Baxter Healthcare Sa Immunogenic betha-propionamido-linked polysaccharide protein conjugate useful as a vaccine produced using an n-acryloylated polysaccharide
US6436653B1 (en) 1998-12-15 2002-08-20 Exiqon A/S Method for introduction of reporter groups into bacterial lipopolysaccharide-derived carbohydrates and the subsequent coupling of such derivatives onto solid surfaces
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
US6518037B2 (en) * 1999-11-12 2003-02-11 University Of Iowa Research Foundation Two-component system that controls bacterial membrane synthesis
GB9928196D0 (en) * 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
GB0011108D0 (en) * 2000-05-08 2000-06-28 Microscience Ltd Virulence gene and protein and their use
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US7534444B2 (en) 2001-04-17 2009-05-19 Novattis Vaccines And Diagnostics, Inc. Molecular mimetics of meningococcal B epitopes which elicit functionally active antibodies
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
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Also Published As

Publication number Publication date
HU9201966D0 (en) 1992-10-28
US5576002A (en) 1996-11-19
FI104539B (fi) 2000-02-29
US5683699A (en) 1997-11-04
ATE121947T1 (de) 1995-05-15
CA2071811A1 (en) 1991-06-15
NO973311L (no) 1992-08-14
NO922316L (no) 1992-08-14
CN1036522C (zh) 1997-11-26
NZ236471A (en) 1992-10-28
FI19991917L (fi) 1999-09-09
FI922737A0 (fi) 1992-06-12
CN1072506C (zh) 2001-10-10
CN1055541A (zh) 1991-10-23
US5902586A (en) 1999-05-11
CN1049223C (zh) 2000-02-09
RO111416B1 (ro) 1996-10-31
SI20008A (sl) 2000-02-29
PL166659B1 (pl) 1995-06-30
AR243934A1 (es) 1993-09-30
EP0504202B1 (en) 1995-05-03
CN1036504C (zh) 1997-11-26
HUT64480A (en) 1994-01-28
CN1100428A (zh) 1995-03-22
IL96676A (en) 1996-09-12
ES2071288T3 (es) 1995-06-16
PH30305A (en) 1997-02-20
PL166035B1 (pl) 1995-03-31
BR9007917A (pt) 1992-10-20
RU2105568C1 (ru) 1998-02-27
CZ283530B6 (cs) 1998-04-15
NO973311D0 (no) 1997-07-17
SI20008B (en) 2001-02-28
DE69019164T2 (de) 1995-09-07
EP0504202A1 (en) 1992-09-23
JPH05505392A (ja) 1993-08-12
IN171747B (Direct) 1992-12-26
ZA9010065B (en) 1992-02-26
NO307835B1 (no) 2000-06-05
CN1096516A (zh) 1994-12-21
IE904513A1 (en) 1991-06-19
CN1100656A (zh) 1995-03-29
AU641715B2 (en) 1993-09-30
NO305275B1 (no) 1999-05-03
YU24391A (sh) 1995-12-04
IL96676A0 (en) 1991-09-16
PL288271A1 (en) 1991-12-16
FI19991917A7 (fi) 1999-09-09
DK0504202T3 (da) 1995-10-02
HRP920872A2 (en) 1997-06-30
CZ628490A3 (en) 1997-12-17
CA2071811C (en) 2003-11-04
IE68414B1 (en) 1996-06-12
WO1991008772A1 (en) 1991-06-27
KR0158436B1 (ko) 1998-12-01
AU6898791A (en) 1991-07-18
JP2637845B2 (ja) 1997-08-06
DE69019164D1 (de) 1995-06-08
NO922316D0 (no) 1992-06-12

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