HU182449B - Process for preparing new 3,4,5-trihydroxy-piperidine derivatives - Google Patents
Process for preparing new 3,4,5-trihydroxy-piperidine derivatives Download PDFInfo
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- HU182449B HU182449B HU78BA3696A HUBA003696A HU182449B HU 182449 B HU182449 B HU 182449B HU 78BA3696 A HU78BA3696 A HU 78BA3696A HU BA003696 A HUBA003696 A HU BA003696A HU 182449 B HU182449 B HU 182449B
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- 238000004519 manufacturing process Methods 0.000 title description 2
- RMCNETIHECSPMZ-UHFFFAOYSA-N piperidine-3,4,5-triol Chemical class OC1CNCC(O)C1O RMCNETIHECSPMZ-UHFFFAOYSA-N 0.000 title description 2
- 150000001875 compounds Chemical class 0.000 claims description 218
- -1 hydroxy, amino, carboxyl Chemical group 0.000 claims description 175
- 239000000203 mixture Substances 0.000 claims description 69
- 229910052739 hydrogen Inorganic materials 0.000 claims description 49
- 239000001257 hydrogen Substances 0.000 claims description 48
- 238000000034 method Methods 0.000 claims description 35
- 238000006243 chemical reaction Methods 0.000 claims description 33
- 125000000217 alkyl group Chemical group 0.000 claims description 25
- 241001465754 Metazoa Species 0.000 claims description 24
- 230000008569 process Effects 0.000 claims description 22
- 238000002360 preparation method Methods 0.000 claims description 21
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 20
- 125000004093 cyano group Chemical group *C#N 0.000 claims description 19
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 18
- 150000003839 salts Chemical class 0.000 claims description 18
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 17
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 17
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 17
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 claims description 16
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- 208000031226 Hyperlipidaemia Diseases 0.000 claims description 4
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- 125000000043 benzamido group Chemical group [H]N([*])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 5
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/132—Heterocyclic compounds containing only one nitrogen as hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772738717 DE2738717A1 (de) | 1977-08-27 | 1977-08-27 | N-alkylierte derivate der 5-amino- 5-deoxy-d-glucose, verfahren zu ihrer herstellung und ihre verwendung |
| DE19772758025 DE2758025A1 (de) | 1977-12-24 | 1977-12-24 | Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU182449B true HU182449B (en) | 1984-01-30 |
Family
ID=25772626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU78BA3696A HU182449B (en) | 1977-08-27 | 1978-08-25 | Process for preparing new 3,4,5-trihydroxy-piperidine derivatives |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US4639436A (OSRAM) |
| EP (1) | EP0000947B2 (OSRAM) |
| JP (1) | JPS5446786A (OSRAM) |
| AT (1) | AT373239B (OSRAM) |
| AU (2) | AU3921478A (OSRAM) |
| CA (1) | CA1123437A (OSRAM) |
| DE (1) | DE2860330D1 (OSRAM) |
| DK (1) | DK152753C (OSRAM) |
| ES (1) | ES472838A1 (OSRAM) |
| FI (1) | FI72715C (OSRAM) |
| GR (1) | GR73065B (OSRAM) |
| HU (1) | HU182449B (OSRAM) |
| IE (1) | IE47070B1 (OSRAM) |
| IL (1) | IL55423A (OSRAM) |
| IT (1) | IT1111197B (OSRAM) |
| LU (1) | LU90211I2 (OSRAM) |
| NL (1) | NL960027I2 (OSRAM) |
| NO (1) | NO154918C (OSRAM) |
| PT (1) | PT68474A (OSRAM) |
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|---|---|---|---|---|
| GB1555654A (en) * | 1977-06-25 | 1979-11-14 | Exxon Research Engineering Co | Agricultural burner apparatus |
| DE2660486C2 (de) * | 1975-12-29 | 1984-03-08 | Nippon Shinyaku Co., Ltd., Kyoto | Verwendung von 2-Hydroxymethyl-3,4,5-trihydroxypiperidin als Arzneimittel |
| US4065562A (en) * | 1975-12-29 | 1977-12-27 | Nippon Shinyaku Co., Ltd. | Method and composition for reducing blood glucose levels |
| GB2020278B (en) * | 1978-05-03 | 1983-02-23 | Nippon Shinyaku Co Ltd | Moranoline dervitives |
| JPS5943948B2 (ja) * | 1978-07-06 | 1984-10-25 | 日本新薬株式会社 | 置換モラノリン誘導体 |
| DE2830469A1 (de) * | 1978-07-11 | 1980-01-24 | Bayer Ag | Herstellung von l-desoxy-nojirimycin und n-substituierten derivaten |
| JPS5943948A (ja) * | 1982-09-03 | 1984-03-12 | Toyota Motor Corp | 可変ベンチユリ型気化器 |
-
1978
- 1978-08-09 NO NO782713A patent/NO154918C/no unknown
- 1978-08-23 US US05/936,280 patent/US4639436A/en not_active Expired - Lifetime
- 1978-08-24 IL IL55423A patent/IL55423A/xx active IP Right Grant
- 1978-08-24 GR GR57073A patent/GR73065B/el unknown
- 1978-08-24 AU AU39214/78A patent/AU3921478A/en active Pending
- 1978-08-24 PT PT68474A patent/PT68474A/pt unknown
- 1978-08-25 CA CA310,084A patent/CA1123437A/en not_active Expired
- 1978-08-25 IE IE1716/78A patent/IE47070B1/en not_active IP Right Cessation
- 1978-08-25 FI FI782607A patent/FI72715C/fi not_active IP Right Cessation
- 1978-08-25 HU HU78BA3696A patent/HU182449B/hu unknown
- 1978-08-25 AT AT0621778A patent/AT373239B/de not_active IP Right Cessation
- 1978-08-25 ES ES472838A patent/ES472838A1/es not_active Expired
- 1978-08-25 JP JP10297478A patent/JPS5446786A/ja active Granted
- 1978-08-25 DE DE7878100750T patent/DE2860330D1/de not_active Expired
- 1978-08-25 EP EP78100750A patent/EP0000947B2/de not_active Expired
- 1978-08-25 IT IT27067/78A patent/IT1111197B/it active
- 1978-08-25 DK DK377678A patent/DK152753C/da not_active IP Right Cessation
- 1978-08-28 AU AU39304/78A patent/AU520686B2/en not_active Expired
-
1979
- 1979-09-20 US US06/077,507 patent/US4260622A/en not_active Expired - Lifetime
-
1996
- 1996-10-21 NL NL960027C patent/NL960027I2/nl unknown
-
1998
- 1998-02-04 LU LU90211C patent/LU90211I2/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5446786A (en) | 1979-04-12 |
| US4639436A (en) | 1987-01-27 |
| LU90211I2 (fr) | 1998-04-08 |
| FI72715C (fi) | 1987-07-10 |
| AU3930478A (en) | 1980-03-06 |
| IT1111197B (it) | 1986-01-13 |
| NO154918C (no) | 1987-01-14 |
| IE47070B1 (en) | 1983-12-14 |
| EP0000947B1 (de) | 1981-01-14 |
| IL55423A0 (en) | 1978-10-31 |
| PT68474A (de) | 1978-09-01 |
| IT7827067A0 (it) | 1978-08-25 |
| ES472838A1 (es) | 1979-03-16 |
| GR73065B (OSRAM) | 1984-01-30 |
| EP0000947B2 (de) | 1984-10-10 |
| JPS6231703B2 (OSRAM) | 1987-07-09 |
| NO782713L (no) | 1979-02-28 |
| DK377678A (da) | 1979-02-28 |
| NO154918B (no) | 1986-10-06 |
| DK152753B (da) | 1988-05-09 |
| US4260622A (en) | 1981-04-07 |
| IL55423A (en) | 1982-09-30 |
| EP0000947A1 (de) | 1979-03-07 |
| AU520686B2 (en) | 1982-02-18 |
| AU3921478A (en) | 1980-02-28 |
| DE2860330D1 (en) | 1981-03-12 |
| FI782607A7 (fi) | 1979-02-28 |
| CA1123437A (en) | 1982-05-11 |
| AT373239B (de) | 1983-12-27 |
| FI72715B (fi) | 1987-03-31 |
| ATA621778A (de) | 1983-05-15 |
| NL960027I1 (nl) | 1997-01-06 |
| DK152753C (da) | 1988-10-31 |
| NL960027I2 (nl) | 1997-07-01 |
| IE781716L (en) | 1979-02-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 |