HU180002B - Process for producing new 4-figure bracket-p-square bracket-bis-bracket-2-chloro-ethyl-bracket closed-amino-square bracket closed-phenyl-figure bracket closed-buty ic acid derivatives for estradiol - Google Patents
Process for producing new 4-figure bracket-p-square bracket-bis-bracket-2-chloro-ethyl-bracket closed-amino-square bracket closed-phenyl-figure bracket closed-buty ic acid derivatives for estradiol Download PDFInfo
- Publication number
- HU180002B HU180002B HU79KU545A HUKU000545A HU180002B HU 180002 B HU180002 B HU 180002B HU 79KU545 A HU79KU545 A HU 79KU545A HU KU000545 A HUKU000545 A HU KU000545A HU 180002 B HU180002 B HU 180002B
- Authority
- HU
- Hungary
- Prior art keywords
- estradiol
- bis
- phenyl
- amino
- bracket
- Prior art date
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- 229930182833 estradiol Natural products 0.000 title claims abstract description 32
- 238000000034 method Methods 0.000 title claims abstract description 17
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- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 238000002211 ultraviolet spectrum Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0074—Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP53098795A JPS5810393B2 (ja) | 1978-08-14 | 1978-08-14 | 新規なエストラジオ−ル結合体とその製造方法及び抗腫瘍剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU180002B true HU180002B (en) | 1983-01-28 |
Family
ID=14229286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU79KU545A HU180002B (en) | 1978-08-14 | 1979-07-19 | Process for producing new 4-figure bracket-p-square bracket-bis-bracket-2-chloro-ethyl-bracket closed-amino-square bracket closed-phenyl-figure bracket closed-buty ic acid derivatives for estradiol |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS5810393B2 (cs) |
| BE (1) | BE878186A (cs) |
| CS (1) | CS242856B2 (cs) |
| GE (1) | GEP19960478B (cs) |
| HU (1) | HU180002B (cs) |
| SU (1) | SU1001860A3 (cs) |
| UA (1) | UA6043A1 (cs) |
| YU (1) | YU41345B (cs) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2169900B (en) * | 1984-06-27 | 1988-02-17 | Onkologi N Ct Ak Med V | Derivatives of steroids of androstane series |
-
1978
- 1978-08-14 JP JP53098795A patent/JPS5810393B2/ja not_active Expired
-
1979
- 1979-07-19 HU HU79KU545A patent/HU180002B/hu not_active IP Right Cessation
- 1979-08-10 BE BE0/196683A patent/BE878186A/fr not_active IP Right Cessation
- 1979-08-13 SU SU792804752A patent/SU1001860A3/ru active
- 1979-08-13 UA UA2804752A patent/UA6043A1/uk unknown
- 1979-08-14 CS CS795566A patent/CS242856B2/cs unknown
- 1979-08-14 YU YU1981/79A patent/YU41345B/xx unknown
-
1994
- 1994-09-07 GE GEAP19942153A patent/GEP19960478B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CS556679A2 (en) | 1985-08-15 |
| UA6043A1 (uk) | 1994-12-29 |
| YU198179A (en) | 1983-01-21 |
| JPS5810393B2 (ja) | 1983-02-25 |
| BE878186A (fr) | 1980-02-11 |
| JPS5527121A (en) | 1980-02-27 |
| CS242856B2 (en) | 1986-05-15 |
| YU41345B (en) | 1987-02-28 |
| SU1001860A3 (ru) | 1983-02-28 |
| GEP19960478B (en) | 1996-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee |