HU176820B - Process for preparing phenyl-piperazine derivatives - Google Patents
Process for preparing phenyl-piperazine derivatives Download PDFInfo
- Publication number
- HU176820B HU176820B HU77LI311A HULI000311A HU176820B HU 176820 B HU176820 B HU 176820B HU 77LI311 A HU77LI311 A HU 77LI311A HU LI000311 A HULI000311 A HU LI000311A HU 176820 B HU176820 B HU 176820B
- Authority
- HU
- Hungary
- Prior art keywords
- phenyl
- formula
- piperazine
- ylmethyl
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Furan Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB16526/76A GB1575904A (en) | 1976-04-23 | 1976-04-23 | Phenyl piperazines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU176820B true HU176820B (en) | 1981-05-28 |
Family
ID=10078930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU77LI311A HU176820B (en) | 1976-04-23 | 1977-04-22 | Process for preparing phenyl-piperazine derivatives |
Country Status (34)
| Country | Link |
|---|---|
| JP (1) | JPS52151183A (xx) |
| AR (2) | AR222003A1 (xx) |
| AT (1) | AT355579B (xx) |
| AU (1) | AU514822B2 (xx) |
| BE (1) | BE853899A (xx) |
| BG (2) | BG27746A3 (xx) |
| CA (1) | CA1087617A (xx) |
| CH (2) | CH633009A5 (xx) |
| CS (1) | CS196360B2 (xx) |
| DD (1) | DD129790A5 (xx) |
| DE (1) | DE2717415A1 (xx) |
| DK (1) | DK176177A (xx) |
| ES (2) | ES457988A1 (xx) |
| FI (1) | FI63937C (xx) |
| FR (1) | FR2348925A1 (xx) |
| GB (1) | GB1575904A (xx) |
| GR (1) | GR64084B (xx) |
| HU (1) | HU176820B (xx) |
| IE (1) | IE44730B1 (xx) |
| IL (1) | IL51787A (xx) |
| LU (1) | LU77170A1 (xx) |
| MX (1) | MX4596E (xx) |
| NL (1) | NL7704456A (xx) |
| NO (1) | NO146710C (xx) |
| NZ (1) | NZ183715A (xx) |
| OA (1) | OA05643A (xx) |
| PH (1) | PH14124A (xx) |
| PL (1) | PL117466B1 (xx) |
| PT (1) | PT66452B (xx) |
| RO (1) | RO72831A (xx) |
| SE (1) | SE7704536L (xx) |
| SU (2) | SU664564A3 (xx) |
| YU (1) | YU104477A (xx) |
| ZA (1) | ZA771849B (xx) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1601310A (en) * | 1978-05-23 | 1981-10-28 | Lilly Industries Ltd | Aryl hydantoins |
| DE3142608A1 (de) * | 1981-10-28 | 1983-05-05 | Basf Ag, 6700 Ludwigshafen | Polyazofarbstoffe |
| JPH07157477A (ja) * | 1993-12-02 | 1995-06-20 | Asahi Kagaku Kogyo Kk | チアゾール誘導体の製造方法 |
| KR970701705A (ko) * | 1994-03-11 | 1997-04-12 | 오노다 마사요시 | 5-HT₃ 수용체 효능제, 신규한 티아졸 유도체 및 이의 중간체(5-HT₃receptor agonist, novel thiazole derivative, and intermediate therefor) |
| GB9517381D0 (en) * | 1995-08-24 | 1995-10-25 | Pharmacia Spa | Aryl and heteroaryl piperazine derivatives |
| US8927546B2 (en) | 2006-02-28 | 2015-01-06 | Dart Neuroscience (Cayman) Ltd. | Therapeutic piperazines |
| ES2462240T3 (es) * | 2006-02-28 | 2014-05-22 | Dart Neuroscience (Cayman) Ltd | Piperazinas terapéuticas como inhibidores de PDE4 |
-
1976
- 1976-04-23 GB GB16526/76A patent/GB1575904A/en not_active Expired
-
1977
- 1977-03-28 ZA ZA00771849A patent/ZA771849B/xx unknown
- 1977-03-28 NZ NZ183715A patent/NZ183715A/xx unknown
- 1977-03-30 IE IE671/77A patent/IE44730B1/en unknown
- 1977-03-30 CA CA275,160A patent/CA1087617A/en not_active Expired
- 1977-03-30 IL IL51787A patent/IL51787A/xx unknown
- 1977-04-13 CH CH525781A patent/CH633009A5/fr not_active IP Right Cessation
- 1977-04-13 CH CH455777A patent/CH625802A5/fr not_active IP Right Cessation
- 1977-04-13 MX MX775629U patent/MX4596E/es unknown
- 1977-04-14 PH PH19656A patent/PH14124A/en unknown
- 1977-04-18 PT PT66452A patent/PT66452B/pt unknown
- 1977-04-18 AU AU24386/77A patent/AU514822B2/en not_active Expired
- 1977-04-19 GR GR53236A patent/GR64084B/el unknown
- 1977-04-19 FR FR7711669A patent/FR2348925A1/fr active Granted
- 1977-04-20 OA OA56149A patent/OA05643A/xx unknown
- 1977-04-20 ES ES457988A patent/ES457988A1/es not_active Expired
- 1977-04-20 RO RO7790106A patent/RO72831A/ro unknown
- 1977-04-20 BG BG7736062A patent/BG27746A3/xx unknown
- 1977-04-20 DE DE19772717415 patent/DE2717415A1/de not_active Withdrawn
- 1977-04-20 BG BG7737191A patent/BG28055A3/xx unknown
- 1977-04-20 SE SE7704536A patent/SE7704536L/xx not_active Application Discontinuation
- 1977-04-21 YU YU01044/77A patent/YU104477A/xx unknown
- 1977-04-21 LU LU77170A patent/LU77170A1/xx unknown
- 1977-04-21 DK DK176177A patent/DK176177A/da not_active Application Discontinuation
- 1977-04-21 CS CS772668A patent/CS196360B2/cs unknown
- 1977-04-22 NO NO771398A patent/NO146710C/no unknown
- 1977-04-22 AR AR267310A patent/AR222003A1/es active
- 1977-04-22 AT AT285177A patent/AT355579B/de not_active IP Right Cessation
- 1977-04-22 SU SU772474105A patent/SU664564A3/ru active
- 1977-04-22 HU HU77LI311A patent/HU176820B/hu unknown
- 1977-04-22 NL NL7704456A patent/NL7704456A/xx not_active Application Discontinuation
- 1977-04-22 BE BE6045977A patent/BE853899A/xx not_active IP Right Cessation
- 1977-04-22 PL PL1977197550A patent/PL117466B1/pl unknown
- 1977-04-22 FI FI771287A patent/FI63937C/fi not_active IP Right Cessation
- 1977-04-22 DD DD7700198558A patent/DD129790A5/xx unknown
- 1977-04-23 JP JP4727677A patent/JPS52151183A/ja active Pending
- 1977-12-28 SU SU772558499A patent/SU727146A3/ru active
-
1978
- 1978-03-16 ES ES467948A patent/ES467948A1/es not_active Expired
- 1978-03-22 AR AR271519A patent/AR222635A1/es active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7396842B2 (en) | Five-membered cyclic compounds | |
| EP0149884B1 (en) | 5-pyridyl-1,3-thiazole derivatives, their production and use | |
| AU2009209885B2 (en) | Thiazole derivative and use thereof as VAP-1 inhibitor | |
| BRPI0710266B1 (pt) | Composto, medicamento, e, uso de um composto | |
| JP2758077B2 (ja) | 複素環式誘導体、その製造方法、ならびに治療的用途 | |
| EP0190015A1 (en) | Novel 4H-1-benzopyran-4-ones and their sulphur containing analogs | |
| US4123529A (en) | Phenylpiperazine derivatives | |
| HU176820B (en) | Process for preparing phenyl-piperazine derivatives | |
| HU207731B (en) | Process for producing aryl-piperazinyl-alkylene-phenyl-p-heterocyclic compounds, pharmaceutically acceptable acid additional salts and pharmaceutical compositions containing them as active components | |
| US3476766A (en) | Certain 2,4 - diarylthiazole-5-alkanoic acids and derivatives thereof | |
| US4147698A (en) | 3-(Heterocyclicalkylamino)benzisothiazole-1,1-dioxides | |
| US4935424A (en) | 4 or 5-(substituted piperazinylalkyl)-2-aminothiazoles as antipsychotic agents | |
| CA1333906C (en) | Cycloalkylthiazole derivatives | |
| HU214337B (hu) | Eljárás 1,3,4-tiadiazin-2-on-származékok és az azokat tartalmazó gyógyszer készítmények előállítására | |
| US4711889A (en) | Schistosomicidal acridanone hydrazones | |
| JPS6360978A (ja) | アミノチアゾ−ル化合物 | |
| US4344946A (en) | 2,6-Diamino-benzo[1,2-d:5,4-d']bisthiazoles and salts thereof | |
| PL164152B1 (pl) | Sposób wytwarzania nowych pochodnych 2-iminobenzotiazoliny PL | |
| US5096902A (en) | Heterocyclic compounds containing nitrogen and sulfur, pharmaceutical compositions containing them and process for preparing same | |
| KR20020058020A (ko) | 술포닐 옥사졸 아민 및 ５-ｈｔ６ 수용체 리간드로서의이의 용도 | |
| HU190669B (en) | Process for preparing 3,4-disubstituted 1,2,5-thiadiazole-1-oxides and -1,1-dioxides | |
| KR810000758B1 (ko) | 페닐 피페라진 유도체의 제조방법 | |
| JPS61115074A (ja) | ３，４‐ジアゾール誘導体、その製法、およびその化合物を含有する医薬品 | |
| GB2265369A (en) | 2-(substituted imino)-thiazolidines and process for the preparation thereof | |
| JPS59167588A (ja) | チアジアゾ−ル誘導体 |