AT355579B - Verfahren zur herstellung von neuen phenyl- piperazinderivaten und deren salzen - Google Patents

Verfahren zur herstellung von neuen phenyl- piperazinderivaten und deren salzen

Info

Publication number
AT355579B
AT355579B AT285177A AT285177A AT355579B AT 355579 B AT355579 B AT 355579B AT 285177 A AT285177 A AT 285177A AT 285177 A AT285177 A AT 285177A AT 355579 B AT355579 B AT 355579B
Authority
AT
Austria
Prior art keywords
salts
piperazine derivatives
producing new
phenyl piperazine
new phenyl
Prior art date
Application number
AT285177A
Other languages
English (en)
Other versions
ATA285177A (de
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of ATA285177A publication Critical patent/ATA285177A/de
Application granted granted Critical
Publication of AT355579B publication Critical patent/AT355579B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/42—Singly bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
AT285177A 1976-04-23 1977-04-22 Verfahren zur herstellung von neuen phenyl- piperazinderivaten und deren salzen AT355579B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB16526/76A GB1575904A (en) 1976-04-23 1976-04-23 Phenyl piperazines

Publications (2)

Publication Number Publication Date
ATA285177A ATA285177A (de) 1979-08-15
AT355579B true AT355579B (de) 1980-03-10

Family

ID=10078930

Family Applications (1)

Application Number Title Priority Date Filing Date
AT285177A AT355579B (de) 1976-04-23 1977-04-22 Verfahren zur herstellung von neuen phenyl- piperazinderivaten und deren salzen

Country Status (34)

Country Link
JP (1) JPS52151183A (de)
AR (2) AR222003A1 (de)
AT (1) AT355579B (de)
AU (1) AU514822B2 (de)
BE (1) BE853899A (de)
BG (2) BG27746A3 (de)
CA (1) CA1087617A (de)
CH (2) CH633009A5 (de)
CS (1) CS196360B2 (de)
DD (1) DD129790A5 (de)
DE (1) DE2717415A1 (de)
DK (1) DK176177A (de)
ES (2) ES457988A1 (de)
FI (1) FI63937C (de)
FR (1) FR2348925A1 (de)
GB (1) GB1575904A (de)
GR (1) GR64084B (de)
HU (1) HU176820B (de)
IE (1) IE44730B1 (de)
IL (1) IL51787A (de)
LU (1) LU77170A1 (de)
MX (1) MX4596E (de)
NL (1) NL7704456A (de)
NO (1) NO146710C (de)
NZ (1) NZ183715A (de)
OA (1) OA05643A (de)
PH (1) PH14124A (de)
PL (1) PL117466B1 (de)
PT (1) PT66452B (de)
RO (1) RO72831A (de)
SE (1) SE7704536L (de)
SU (2) SU664564A3 (de)
YU (1) YU104477A (de)
ZA (1) ZA771849B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1601310A (en) * 1978-05-23 1981-10-28 Lilly Industries Ltd Aryl hydantoins
DE3142608A1 (de) * 1981-10-28 1983-05-05 Basf Ag, 6700 Ludwigshafen Polyazofarbstoffe
JPH07157477A (ja) * 1993-12-02 1995-06-20 Asahi Kagaku Kogyo Kk チアゾール誘導体の製造方法
NZ281718A (en) * 1994-03-11 1997-08-22 Yamanouchi Pharma Co Ltd Heterocyclically-substituted (condensed) thiazoles
GB9517381D0 (en) * 1995-08-24 1995-10-25 Pharmacia Spa Aryl and heteroaryl piperazine derivatives
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
ES2462240T3 (es) 2006-02-28 2014-05-22 Dart Neuroscience (Cayman) Ltd Piperazinas terapéuticas como inhibidores de PDE4

Also Published As

Publication number Publication date
AR222003A1 (es) 1981-04-15
CS196360B2 (en) 1980-03-31
DD129790A5 (de) 1978-02-08
YU104477A (en) 1983-01-21
FI771287A (de) 1977-10-24
HU176820B (en) 1981-05-28
FR2348925B1 (de) 1980-04-11
NZ183715A (en) 1980-04-28
NL7704456A (nl) 1977-10-25
NO146710C (no) 1982-11-24
IE44730B1 (en) 1982-03-10
JPS52151183A (en) 1977-12-15
DE2717415A1 (de) 1977-11-10
OA05643A (fr) 1981-04-30
PL197550A1 (pl) 1979-05-21
ES467948A1 (es) 1978-11-01
FR2348925A1 (fr) 1977-11-18
IL51787A0 (en) 1977-05-31
ATA285177A (de) 1979-08-15
CH633009A5 (en) 1982-11-15
SU664564A3 (ru) 1979-05-25
SE7704536L (sv) 1977-10-24
BE853899A (fr) 1977-10-24
AU514822B2 (en) 1981-02-26
SU727146A3 (ru) 1980-04-05
RO72831B (ro) 1983-07-30
IL51787A (en) 1980-02-29
BG27746A3 (en) 1979-12-12
PT66452B (en) 1979-03-09
FI63937B (fi) 1983-05-31
PT66452A (en) 1977-05-01
AR222635A1 (es) 1981-06-15
AU2438677A (en) 1978-10-26
DK176177A (da) 1977-10-24
MX4596E (es) 1982-06-25
GR64084B (en) 1980-01-21
GB1575904A (en) 1980-10-01
IE44730L (en) 1977-10-23
RO72831A (ro) 1983-08-03
FI63937C (fi) 1983-09-12
NO771398L (no) 1977-10-25
ES457988A1 (es) 1978-07-16
ZA771849B (en) 1978-11-29
CA1087617A (en) 1980-10-14
BG28055A3 (en) 1980-02-25
LU77170A1 (de) 1979-01-18
NO146710B (no) 1982-08-16
PH14124A (en) 1981-02-26
PL117466B1 (en) 1981-08-31
CH625802A5 (en) 1981-10-15

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Legal Events

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ELJ Ceased due to non-payment of the annual fee