IL51787A - 1 heterocyclylalkyl 4 phenyl piperazine derivatives their preparation and pharmaceutical compositions containing them - Google Patents

1 heterocyclylalkyl 4 phenyl piperazine derivatives their preparation and pharmaceutical compositions containing them

Info

Publication number
IL51787A
IL51787A IL51787A IL5178777A IL51787A IL 51787 A IL51787 A IL 51787A IL 51787 A IL51787 A IL 51787A IL 5178777 A IL5178777 A IL 5178777A IL 51787 A IL51787 A IL 51787A
Authority
IL
Israel
Prior art keywords
heterocyclylalkyl
preparation
pharmaceutical compositions
compositions containing
piperazine derivatives
Prior art date
Application number
IL51787A
Other languages
English (en)
Other versions
IL51787A0 (en
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of IL51787A0 publication Critical patent/IL51787A0/xx
Publication of IL51787A publication Critical patent/IL51787A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/42Singly bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL51787A 1976-04-23 1977-03-30 1 heterocyclylalkyl 4 phenyl piperazine derivatives their preparation and pharmaceutical compositions containing them IL51787A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB16526/76A GB1575904A (en) 1976-04-23 1976-04-23 Phenyl piperazines

Publications (2)

Publication Number Publication Date
IL51787A0 IL51787A0 (en) 1977-05-31
IL51787A true IL51787A (en) 1980-02-29

Family

ID=10078930

Family Applications (1)

Application Number Title Priority Date Filing Date
IL51787A IL51787A (en) 1976-04-23 1977-03-30 1 heterocyclylalkyl 4 phenyl piperazine derivatives their preparation and pharmaceutical compositions containing them

Country Status (34)

Country Link
JP (1) JPS52151183A (xx)
AR (2) AR222003A1 (xx)
AT (1) AT355579B (xx)
AU (1) AU514822B2 (xx)
BE (1) BE853899A (xx)
BG (2) BG27746A3 (xx)
CA (1) CA1087617A (xx)
CH (2) CH633009A5 (xx)
CS (1) CS196360B2 (xx)
DD (1) DD129790A5 (xx)
DE (1) DE2717415A1 (xx)
DK (1) DK176177A (xx)
ES (2) ES457988A1 (xx)
FI (1) FI63937C (xx)
FR (1) FR2348925A1 (xx)
GB (1) GB1575904A (xx)
GR (1) GR64084B (xx)
HU (1) HU176820B (xx)
IE (1) IE44730B1 (xx)
IL (1) IL51787A (xx)
LU (1) LU77170A1 (xx)
MX (1) MX4596E (xx)
NL (1) NL7704456A (xx)
NO (1) NO146710C (xx)
NZ (1) NZ183715A (xx)
OA (1) OA05643A (xx)
PH (1) PH14124A (xx)
PL (1) PL117466B1 (xx)
PT (1) PT66452B (xx)
RO (1) RO72831A (xx)
SE (1) SE7704536L (xx)
SU (2) SU664564A3 (xx)
YU (1) YU104477A (xx)
ZA (1) ZA771849B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1601310A (en) * 1978-05-23 1981-10-28 Lilly Industries Ltd Aryl hydantoins
DE3142608A1 (de) * 1981-10-28 1983-05-05 Basf Ag, 6700 Ludwigshafen Polyazofarbstoffe
JPH07157477A (ja) * 1993-12-02 1995-06-20 Asahi Kagaku Kogyo Kk チアゾール誘導体の製造方法
NZ281718A (en) * 1994-03-11 1997-08-22 Yamanouchi Pharma Co Ltd Heterocyclically-substituted (condensed) thiazoles
GB9517381D0 (en) * 1995-08-24 1995-10-25 Pharmacia Spa Aryl and heteroaryl piperazine derivatives
TW200804309A (en) 2006-02-28 2008-01-16 Helicon Therapeutics Inc Therapeutic piperazines
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines

Also Published As

Publication number Publication date
SE7704536L (sv) 1977-10-24
LU77170A1 (xx) 1979-01-18
ZA771849B (en) 1978-11-29
SU664564A3 (ru) 1979-05-25
GB1575904A (en) 1980-10-01
IE44730L (en) 1977-10-23
PH14124A (en) 1981-02-26
ES467948A1 (es) 1978-11-01
PT66452A (en) 1977-05-01
CS196360B2 (en) 1980-03-31
HU176820B (en) 1981-05-28
GR64084B (en) 1980-01-21
FI771287A (xx) 1977-10-24
ES457988A1 (es) 1978-07-16
DK176177A (da) 1977-10-24
NO771398L (no) 1977-10-25
AU514822B2 (en) 1981-02-26
AR222635A1 (es) 1981-06-15
BG28055A3 (en) 1980-02-25
FI63937C (fi) 1983-09-12
SU727146A3 (ru) 1980-04-05
NO146710C (no) 1982-11-24
FR2348925B1 (xx) 1980-04-11
RO72831A (ro) 1983-08-03
NZ183715A (en) 1980-04-28
BG27746A3 (en) 1979-12-12
AU2438677A (en) 1978-10-26
FI63937B (fi) 1983-05-31
YU104477A (en) 1983-01-21
CH633009A5 (en) 1982-11-15
PL117466B1 (en) 1981-08-31
DD129790A5 (de) 1978-02-08
OA05643A (fr) 1981-04-30
ATA285177A (de) 1979-08-15
IE44730B1 (en) 1982-03-10
NL7704456A (nl) 1977-10-25
AR222003A1 (es) 1981-04-15
AT355579B (de) 1980-03-10
JPS52151183A (en) 1977-12-15
RO72831B (ro) 1983-07-30
BE853899A (fr) 1977-10-24
DE2717415A1 (de) 1977-11-10
MX4596E (es) 1982-06-25
CH625802A5 (en) 1981-10-15
CA1087617A (en) 1980-10-14
NO146710B (no) 1982-08-16
PT66452B (en) 1979-03-09
IL51787A0 (en) 1977-05-31
FR2348925A1 (fr) 1977-11-18
PL197550A1 (pl) 1979-05-21

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