HRP970255B1 - Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them - Google Patents

Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them

Info

Publication number
HRP970255B1
HRP970255B1 HR970255A HRP970255A HRP970255B1 HR P970255 B1 HRP970255 B1 HR P970255B1 HR 970255 A HR970255 A HR 970255A HR P970255 A HRP970255 A HR P970255A HR P970255 B1 HRP970255 B1 HR P970255B1
Authority
HR
Croatia
Prior art keywords
medicaments
preparation
well
diagnostic agents
chromane derivatives
Prior art date
Application number
HR970255A
Other languages
English (en)
Inventor
Hans-Jochen Lang
Uwe Gerlach
Joachim Brendel
Heinrich Christian Englert
Heinz Goegelein
Max Hropot
Helmut Bohn
Andreas Herling
Andreas Busch
Rainer Greger
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19619614A external-priority patent/DE19619614A1/de
Priority claimed from DE1996139462 external-priority patent/DE19639462A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HRP970255A2 publication Critical patent/HRP970255A2/xx
Publication of HRP970255B1 publication Critical patent/HRP970255B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HR970255A 1996-05-15 1997-05-13 Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them HRP970255B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19619614A DE19619614A1 (de) 1996-05-15 1996-05-15 Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE1996139462 DE19639462A1 (de) 1996-09-26 1996-09-26 Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (2)

Publication Number Publication Date
HRP970255A2 HRP970255A2 (en) 1998-04-30
HRP970255B1 true HRP970255B1 (en) 2003-10-31

Family

ID=26025736

Family Applications (1)

Application Number Title Priority Date Filing Date
HR970255A HRP970255B1 (en) 1996-05-15 1997-05-13 Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them

Country Status (23)

Country Link
EP (1) EP0807629B1 (enExample)
JP (1) JP4234798B2 (enExample)
KR (1) KR100547921B1 (enExample)
CN (1) CN1204134C (enExample)
AR (2) AR007115A1 (enExample)
AT (1) ATE260909T1 (enExample)
AU (1) AU711986B2 (enExample)
BR (1) BR9703161A (enExample)
CA (1) CA2205477A1 (enExample)
CZ (1) CZ149497A3 (enExample)
DE (1) DE59711352D1 (enExample)
DK (1) DK0807629T3 (enExample)
ES (1) ES2218617T3 (enExample)
HR (1) HRP970255B1 (enExample)
HU (1) HUP9700903A3 (enExample)
IL (1) IL120827A (enExample)
NO (1) NO315556B1 (enExample)
NZ (1) NZ314800A (enExample)
PL (1) PL191330B1 (enExample)
PT (1) PT807629E (enExample)
SK (1) SK283837B6 (enExample)
TR (1) TR199700369A2 (enExample)
TW (1) TW496866B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ329200A (en) * 1996-12-16 1999-05-28 Hoechst Ag Sulphonamide substituted quinazoline, isoquinoline, quinoline or benzo[1,3-]oxazine derivatives and medicaments
DE19705133A1 (de) * 1997-02-11 1998-08-13 Hoechst Ag Sulfonamid-substituierte Verbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19706675A1 (de) * 1997-02-20 1998-08-27 Hoechst Ag Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0895994A3 (de) * 1997-08-05 1999-12-15 Hoechst Marion Roussel Deutschland GmbH Sulfonamid-substituierte Pyranopyridine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19742509A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19742508A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19748469A1 (de) * 1997-11-03 1999-05-06 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Benzopyranderivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
JP2002523451A (ja) 1998-09-01 2002-07-30 ブリストル−マイヤーズ スクイブ カンパニー カリウムチャネル抑制剤および方法
DE19858253A1 (de) 1998-12-17 2000-06-21 Aventis Pharma Gmbh Verwendung von Inhibitoren des KQt1-Kanals zur Herstellung eines Medikaments zur Behandlung von Krankheiten, die durch Helminthen und Ektoparasiten hervorgerufen werden
US7368582B2 (en) 2003-10-17 2008-05-06 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them
JP4840594B2 (ja) * 2004-03-23 2011-12-21 日産化学工業株式会社 抗不整脈薬としての３環性ベンゾピラン化合物
US7884109B2 (en) 2005-04-05 2011-02-08 Wyeth Llc Purine and imidazopyridine derivatives for immunosuppression
US7989459B2 (en) 2006-02-17 2011-08-02 Pharmacopeia, Llc Purinones and 1H-imidazopyridinones as PKC-theta inhibitors
US7902187B2 (en) 2006-10-04 2011-03-08 Wyeth Llc 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
TW200831104A (en) 2006-10-04 2008-08-01 Pharmacopeia Inc 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
TW200837064A (en) 2006-10-04 2008-09-16 Pharmacopeia Inc 8-substituted 2-(benzimidazolyl)purine derivatives for immunosuppression
AR076524A1 (es) * 2009-04-30 2011-06-15 Nissan Chemical Ind Ltd Forma cristalina de un compuesto de benzopirano triciclico y metodo de produccion de la misma
TWI583677B (zh) * 2012-09-21 2017-05-21 日本臟器製藥股份有限公司 香豆素衍生物
CN103012380B (zh) * 2013-01-10 2015-03-04 山东大学 一种色满类化合物及其制备方法与应用
JP6089055B2 (ja) * 2014-03-20 2017-03-01 日本臓器製薬株式会社 クマリン誘導体を含有する医薬
AR117169A1 (es) 2018-11-28 2021-07-14 Bayer Ag (tio)amidas de piridazina como compuestos fungicidas
JP7822960B2 (ja) 2020-05-06 2026-03-03 バイエル、アクチエンゲゼルシャフト 殺真菌性化合物としてのピリジン（チオ）アミド
CN115605462B (zh) 2020-05-12 2026-04-14 拜耳公司 作为杀真菌化合物的三嗪和嘧啶(硫代)酰胺
WO2021233861A1 (en) 2020-05-19 2021-11-25 Bayer Aktiengesellschaft Azabicyclic(thio)amides as fungicidal compounds
CN115697059A (zh) 2020-05-27 2023-02-03 拜耳公司 活性化合物组合
US20250064060A1 (en) 2021-11-03 2025-02-27 Bayer Aktiengesellschaft Bis(hetero)aryl thioether (thio)amides as fungicidal compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3737195A1 (de) * 1987-11-03 1989-05-18 Bayer Ag Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
FR2639349B1 (fr) * 1988-11-23 1991-02-22 Sanofi Sa Nouveaux derives du chromane actifs sur le systeme nerveux central, leur procede de preparation et les compositions pharmaceutiques en contenant
US5104890A (en) * 1989-03-28 1992-04-14 Fujisawa Pharmaceutical Company, Ltd. Benzopyran derivatives and processes for preparation thereof

Also Published As

Publication number Publication date
AR010314A1 (es) 2000-06-07
CN1169429A (zh) 1998-01-07
KR19980024020A (ko) 1998-07-06
HU9700903D0 (en) 1997-07-28
KR100547921B1 (ko) 2006-10-19
NO972211L (no) 1997-11-17
BR9703161A (pt) 1998-09-29
PT807629E (pt) 2004-07-30
IL120827A (en) 2004-12-15
AR007115A1 (es) 1999-10-13
SK60397A3 (en) 1998-02-04
CN1204134C (zh) 2005-06-01
JP4234798B2 (ja) 2009-03-04
TW496866B (en) 2002-08-01
HUP9700903A2 (hu) 1998-12-28
SK283837B6 (sk) 2004-03-02
PL191330B1 (pl) 2006-04-28
AU711986B2 (en) 1999-10-28
ES2218617T3 (es) 2004-11-16
TR199700369A2 (xx) 1997-12-21
DK0807629T3 (da) 2004-05-17
DE59711352D1 (de) 2004-04-08
JPH1067772A (ja) 1998-03-10
IL120827A0 (en) 1997-09-30
NO315556B1 (no) 2003-09-22
EP0807629B1 (de) 2004-03-03
CA2205477A1 (en) 1997-11-15
MX9703534A (es) 1997-11-29
PL319995A1 (en) 1997-11-24
HUP9700903A3 (en) 1999-03-01
HRP970255A2 (en) 1998-04-30
CZ149497A3 (en) 1997-12-17
NO972211D0 (no) 1997-05-14
AU2080697A (en) 1997-11-20
NZ314800A (en) 1999-02-25
ATE260909T1 (de) 2004-03-15
HK1006640A1 (en) 1999-03-12
EP0807629A1 (de) 1997-11-19

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Payment date: 20050503

Year of fee payment: 9

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Effective date: 20060514