HRP960253B1 - Process for the hydrogenation of imines - Google Patents

Process for the hydrogenation of imines

Info

Publication number
HRP960253B1
HRP960253B1 HR960253A HRP960253A HRP960253B1 HR P960253 B1 HRP960253 B1 HR P960253B1 HR 960253 A HR960253 A HR 960253A HR P960253 A HRP960253 A HR P960253A HR P960253 B1 HRP960253 B1 HR P960253B1
Authority
HR
Croatia
Prior art keywords
imines
hydrogenation
Prior art date
Application number
HR960253A
Other languages
English (en)
Inventor
Hans-Peter Jalett
Felix Spindler
Reinhard Georg Hanreich
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HRP960253A2 publication Critical patent/HRP960253A2/hr
Publication of HRP960253B1 publication Critical patent/HRP960253B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/52Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/88Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/36Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
HR960253A 1995-06-08 1996-06-05 Process for the hydrogenation of imines HRP960253B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH168595 1995-06-08

Publications (2)

Publication Number Publication Date
HRP960253A2 HRP960253A2 (en) 1997-10-31
HRP960253B1 true HRP960253B1 (en) 2000-10-31

Family

ID=4216210

Family Applications (1)

Application Number Title Priority Date Filing Date
HR960253A HRP960253B1 (en) 1995-06-08 1996-06-05 Process for the hydrogenation of imines

Country Status (26)

Country Link
US (1) US5886225A (cs)
EP (1) EP0830337B1 (cs)
JP (1) JP4128623B2 (cs)
KR (1) KR100470884B1 (cs)
CN (1) CN1176900C (cs)
AR (1) AR002359A1 (cs)
AT (1) ATE187957T1 (cs)
AU (1) AU710870B2 (cs)
BR (1) BR9609159A (cs)
CA (1) CA2220999C (cs)
CZ (1) CZ287315B6 (cs)
DE (1) DE69605794T2 (cs)
DK (1) DK0830337T3 (cs)
EA (1) EA000498B1 (cs)
ES (1) ES2141512T3 (cs)
GR (1) GR3032521T3 (cs)
HR (1) HRP960253B1 (cs)
HU (1) HU229337B1 (cs)
IL (1) IL122184A (cs)
PL (1) PL183317B1 (cs)
PT (1) PT830337E (cs)
SK (1) SK281568B6 (cs)
TW (1) TW346482B (cs)
UA (1) UA51652C2 (cs)
WO (1) WO1996041793A1 (cs)
ZA (1) ZA964832B (cs)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9505836A (pt) * 1994-02-02 1996-02-27 Ciba Geigy Ag Processo para a hidrogenaçao de iminas
US6228971B1 (en) * 1999-06-21 2001-05-08 Ppg Industries Ohio, Inc. Polymeric imine functional compositions and their use in film-forming compositions
US20070213540A1 (en) * 2006-03-09 2007-09-13 Degussa Ag Process for the hydrogenation of imines
US8268872B2 (en) 2008-02-22 2012-09-18 Radius Health, Inc. Selective androgen receptor modulators
EP2260028B1 (en) 2008-02-22 2014-05-07 Radius Health, Inc. Selective androgen receptor modulators
US8987319B2 (en) 2010-02-04 2015-03-24 Radius Health, Inc. Selective androgen receptor modulators
RS54993B1 (sr) 2010-05-12 2016-11-30 Radius Health Inc Terapijski režimi
US8642632B2 (en) 2010-07-02 2014-02-04 Radius Health, Inc. Selective androgen receptor modulators
ES2550319T3 (es) 2010-09-28 2015-11-06 Radius Health, Inc Moduladores selectivos del receptor de andrógenos
CN102153589B (zh) 2011-02-28 2013-01-02 大连多相触媒有限公司 一种亚胺的不对称加氢催化剂及其合成方法和应用
EP2892877B1 (en) 2012-09-06 2017-06-21 Council of Scientific and Industrial Research Process for the preparation of (s)-2-ethyl-n-(1-methoxypropan -2-yl)-6-methyl aniline
US9421264B2 (en) 2014-03-28 2016-08-23 Duke University Method of treating cancer using selective estrogen receptor modulators
LT3122426T (lt) 2014-03-28 2023-03-10 Duke University Krūties vėžio gydymas, naudojant selektyvius estrogenų receptorių moduliatorius
CA3027563A1 (en) 2016-06-22 2017-12-28 Radius Health, Inc. Ar+ breast cancer treatment methods
US10385008B2 (en) 2017-01-05 2019-08-20 Radius Pharmaceuticals, Inc. Polymorphic forms of RAD1901-2HCL
CN112423844A (zh) 2018-07-04 2021-02-26 雷迪厄斯制药公司 Rad1901-2hcl的多晶型形式
CN110305025B (zh) * 2019-07-23 2022-05-06 衢州学院 一种由亚胺催化氢化合成苄胺类化合物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3772487D1 (de) * 1986-08-04 1991-10-02 Ciba Geigy Ag Verfahren zur herstellung von optisch aktiven sekundaeren arylaminen.
US5011995A (en) * 1987-07-28 1991-04-30 Ciba-Geigy Corporation Process for the preparation of optically active secondary amines
US5112999A (en) * 1989-09-18 1992-05-12 Ciba-Geigy Corporation Iridium complexes, process for their preparation and their use
EP0564406B1 (de) * 1992-04-02 1999-05-06 Novartis AG Ferrocenyldiphosphine als Liganden für homogene Katalysatoren
DK0741738T3 (da) * 1994-02-02 2000-04-17 Novartis Ag Hydrogeneringskatallysator, fremgangsmåde til fremstilling deraf og hydrogeneringsfremgangsmåde

Also Published As

Publication number Publication date
ZA964832B (en) 1996-12-09
JPH11507917A (ja) 1999-07-13
SK281568B6 (sk) 2001-05-10
DE69605794D1 (de) 2000-01-27
HUP9802307A3 (en) 1999-03-29
SK168197A3 (en) 1998-05-06
TW346482B (en) 1998-12-01
CA2220999C (en) 2008-01-29
CN1187183A (zh) 1998-07-08
PL183317B1 (pl) 2002-06-28
IL122184A0 (en) 1998-04-05
UA51652C2 (uk) 2002-12-16
CN1176900C (zh) 2004-11-24
WO1996041793A1 (en) 1996-12-27
CA2220999A1 (en) 1996-12-27
US5886225A (en) 1999-03-23
EA000498B1 (ru) 1999-08-26
AR002359A1 (es) 1998-03-11
ATE187957T1 (de) 2000-01-15
EP0830337A1 (en) 1998-03-25
JP4128623B2 (ja) 2008-07-30
BR9609159A (pt) 1999-05-04
IL122184A (en) 2000-02-29
DK0830337T3 (da) 2000-06-13
EP0830337B1 (en) 1999-12-22
KR19990021908A (ko) 1999-03-25
EA199700424A1 (ru) 1999-02-25
HU229337B1 (en) 2013-11-28
AU710870B2 (en) 1999-09-30
KR100470884B1 (ko) 2005-06-22
DE69605794T2 (de) 2000-07-20
GR3032521T3 (en) 2000-05-31
PL323946A1 (en) 1998-04-27
HRP960253A2 (en) 1997-10-31
ES2141512T3 (es) 2000-03-16
CZ391997A3 (cs) 1998-03-18
CZ287315B6 (en) 2000-10-11
PT830337E (pt) 2000-05-31
HUP9802307A2 (hu) 1999-02-01
AU6221896A (en) 1997-01-09

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B1PR Patent granted
PPPP Transfer of rights

Owner name: SYNGENTA PARTICIPATIONS AG, CH

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Payment date: 20150603

Year of fee payment: 20

PB20 Patent expired after termination of 20 years

Effective date: 20160605