HRP20170603T1 - Fermentirana smjesa na bazi soje koja sadrži izoflavone-aglikone, ekvol i lunazin, postupci za pripremu i njihove uporabe u području prehrane, medicine i kozmetike - Google Patents

Fermentirana smjesa na bazi soje koja sadrži izoflavone-aglikone, ekvol i lunazin, postupci za pripremu i njihove uporabe u području prehrane, medicine i kozmetike Download PDF

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HRP20170603T1
HRP20170603T1 HRP20170603TT HRP20170603T HRP20170603T1 HR P20170603 T1 HRP20170603 T1 HR P20170603T1 HR P20170603T T HRP20170603T T HR P20170603TT HR P20170603 T HRP20170603 T HR P20170603T HR P20170603 T1 HRP20170603 T1 HR P20170603T1
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Croatia
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dsm
lactic acid
lactobacillus
acid fermentation
mixture
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HRP20170603TT
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Giammaria Giuliani
Anna Benedusi
Marco Gobbetti
Raffaella Di Cagno
Sergio Baroni
Carlo Giuseppe Rizzello
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Giuliani S.P.A.
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Publication of HRP20170603T1 publication Critical patent/HRP20170603T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C11/00—Milk substitutes, e.g. coffee whitener compositions
    • A23C11/02—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins
    • A23C11/10—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins containing or not lactose but no other milk components as source of fats, carbohydrates or proteins
    • A23C11/103—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins containing or not lactose but no other milk components as source of fats, carbohydrates or proteins containing only proteins from pulses, oilseeds or nuts, e.g. nut milk
    • A23C11/106—Addition of, or treatment with, microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L11/00—Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
    • A23L11/50—Fermented pulses or legumes; Fermentation of pulses or legumes based on the addition of microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23L11/00—Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
    • A23L11/60—Drinks from legumes, e.g. lupine drinks
    • A23L11/65—Soy drinks
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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    • A23V2400/00—Lactic or propionic acid bacteria
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Claims (19)

1. Postupak za pripravu fermentirane smjese na bazi soje, koja sadrži izoflavone-aglikone, ekvol i lunazin, fermentacijom soje koristeći smjesu sljedećih četiriju bakterija mliječnog kiselog vrenja: Lactobacillus plantarum DSM 23755, Lactobacillus plantarum DSM 23756, Lactobacillus fermentum DSM 23757 i Lactobacillus rhamnosus DSM 23758.
2. Postupak u skladu s patentnim zahtjevom 1, obuhvaća ili se sastoji od sljedećih koraka: a) propagiranje kulture navedenih četiriju bakterija mliječnog kiselog vrenja Lactobacillus plantarum DSM 23755, Lactobacillus plantarum DSM 23756, Lactobacillus fermentum DSM 23757 i Lactobacillus rhamnosus DSM 23758; b) inokuliranje supstrata na bazi soje vodenom suspenzijom navedenih bakterija mliječnog kiselog vrenja;
3. inkubiranje na 30-37°C, poželjno 30°C, tijekom 48-96 sati, poželjno 96 sati. 3. Postupak u skladu s patentnim zahtjevom 2, pri čemu se supstrati inokuliraju vodenom suspenzijom bakterija mliječnog kiselog vrenja u količini od 1 do 4% od ukupnog volumena supstrata, navedena vodena suspenzija ima gustoću stanica od otprilike 9,0 cfu/mL za svaki soj.
4. Postupak u skladu s patentnim zahtjevom 2, pri čemu su supstrati na bazi soje odabrani iz grupe koja se sastoji od sojinog brašna, poželjno organski proizvedenog sojinog brašna, sojinog mlijeka.
5. Postupak u skladu s bilo kojim od prethodnih patentnih zahtjeva nadalje obuhvaća korak d) centrifugiranja tekuće kulture kako bi uklonili stanice bakterija mliječnog vrenja.
6. Postupak u skladu s patentnim zahtjevom 5, pri čemu se centrifugiranje tekuće kulture provodi na 10.000 x g tijekom 15 min na temperaturi od 4°C.
7. Postupak u skladu s bilo kojim od prethodnih patentnih zahtjeva nadalje obuhvaća korak e) dehidracije supernatanta dobivenog u koraku d) ili kulture dobivene u koraku c) postupkom sušenja ili liofiliziranja.
8. Fermentirana smjesa na bazi soje, sadrži izoflavone-aglikone, ekvol i lunazin, koji se mogu dobiti postupcima definiranim u bilo kojem od patentnih zahtjeva 1 do 4, navedeni postupci opcionalno nadalje obuhvaćaju korak e) dehidracije kulture dobivene u koraku c) sušenjem ili liofiliziranjem, pri čemu navedena smjesa sadrži sljedeće četiri bakterije mliječnog kiselog vrenja: Lactobacillus plantarum DSM 23755, Lactobacillus plantarum DSM 23756, Lactobacillus fermentum DSM 23757 i Lactobacillus rhamnosus DSM 23758.
9. Farmaceutski ili kozmetički sastav obuhvaća ili se sastoji od smjese koja je definirana u patentnom zahtjevu 8 zajedno s jednim ili više farmaceutski prihvatljivih ekscipijenasa i/ili adjuvanasa.
10. Smjesa u skladu s patentnim zahtjevom 8, kao takva ili u kombinaciji s jednim ili više ekscipijenasa i/ili adjuvansa, za uporabu kao integrator hrane.
11. Smjesa u skladu s patentnim zahtjevom 8 ili sastav u skladu s patentnim zahtjevom 9 za uporabu u liječenju poremećaja ili bolesti kože ili stijenke crijeva.
12. Smjesa u skladu s patentnim zahtjevom 8 ili sastav u skladu s patentnim zahtjevom 9 za kozmetičku uporabu.
13. Smjesa u skladu s patentnim zahtjevom 12 za tretiranje gubitka kose.
14. Smjesa u skladu s patentnim zahtjevom 8 ili sastav u skladu s patentnim zahtjevom 9 za uporabu u liječenju alopecije ili telogen defluviuma.
15. Smjesa sljedećih četiriju bakterija mliječnog kiselog vrenja: Lactobacillus plantarum DSM 23755, Lactobacillus plantarum DSM 23756, Lactobacillus fermentum DSM 23757 i Lactobacillus rhamnosus DSM 23758.
16. Lactobacillus plantarum DSM 23755 bakterija mliječnog kiselog vrenja.
17. Lactobacillus plantarum DSM 23756 bakterija mliječnog kiselog vrenja.
18. Lactobacillus fermentum DSM 23757 bakterija mliječnog kiselog vrenja.
19. Lactobacillus rhamnosus DSM 23758 bakterija mliječnog kiselog vrenja.
HRP20170603TT 2010-07-12 2017-04-18 Fermentirana smjesa na bazi soje koja sadrži izoflavone-aglikone, ekvol i lunazin, postupci za pripremu i njihove uporabe u području prehrane, medicine i kozmetike HRP20170603T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM2010A000378A IT1405780B1 (it) 2010-07-12 2010-07-12 Miscela arricchita di isoflavoni-agliconi, equolo e lunasina a base di soia fermentata, procedimento per la sua preparazione e relativi usi in campo alimentare, medico e cosmetico.
EP11754750.5A EP2593570B1 (en) 2010-07-12 2011-07-11 Fermented soy-based mixture comprising isoflavones-aglycones, equol and lunasil, process for the preparation and uses thereof in food, medical and cosmetic fields
PCT/IT2011/000240 WO2012007978A2 (en) 2010-07-12 2011-07-11 Fermented soya based mixture comprising isoflavones- aglicones, equol and lunasil, process for the preparation and uses thereof in food, medical and cosmetic fields.

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HRP20170603T1 true HRP20170603T1 (hr) 2017-06-30

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Country Link
US (1) US20130231291A1 (hr)
EP (1) EP2593570B1 (hr)
JP (1) JP5951604B2 (hr)
CN (1) CN103140588B (hr)
BR (1) BR112013000778A2 (hr)
CA (1) CA2803322C (hr)
HR (1) HRP20170603T1 (hr)
HU (1) HUE032690T2 (hr)
IT (1) IT1405780B1 (hr)
LT (1) LT2593570T (hr)
MX (1) MX2013000353A (hr)
RS (1) RS55900B1 (hr)
RU (1) RU2564576C2 (hr)
SI (1) SI2593570T1 (hr)
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LT2593570T (lt) 2017-06-26
CN103140588A (zh) 2013-06-05
RS55900B1 (sr) 2017-09-29
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BR112013000778A2 (pt) 2016-06-07
MX2013000353A (es) 2013-03-22
RU2564576C2 (ru) 2015-10-10
CA2803322C (en) 2020-02-25
WO2012007978A2 (en) 2012-01-19
JP5951604B2 (ja) 2016-07-13
US20130231291A1 (en) 2013-09-05
CA2803322A1 (en) 2012-01-19
EP2593570B1 (en) 2017-03-01
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RU2013105731A (ru) 2014-08-20
CN103140588B (zh) 2015-09-30
EP2593570A2 (en) 2013-05-22
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