HRP20120761T1 - Postupak detekcije i dijagnosticiranja raka koji ukljuäśuje poäśetnice i sonde za specifiäśnu detekciju markera mage-a3 - Google Patents

Postupak detekcije i dijagnosticiranja raka koji ukljuäśuje poäśetnice i sonde za specifiäśnu detekciju markera mage-a3 Download PDF

Info

Publication number
HRP20120761T1
HRP20120761T1 HRP20120761TT HRP20120761T HRP20120761T1 HR P20120761 T1 HRP20120761 T1 HR P20120761T1 HR P20120761T T HRP20120761T T HR P20120761TT HR P20120761 T HRP20120761 T HR P20120761T HR P20120761 T1 HRP20120761 T1 HR P20120761T1
Authority
HR
Croatia
Prior art keywords
seq
probe
nucleotide sequence
primer
mage
Prior art date
Application number
HRP20120761TT
Other languages
English (en)
Croatian (hr)
Inventor
Thierry Coche
Olivier Gruselle
Gabriele Anne-Marie Beer
Dennis Salonga
Craig Lawrence Stephens
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of HRP20120761T1 publication Critical patent/HRP20120761T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0091—Purification or manufacturing processes for gene therapy compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Manufacturing & Machinery (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HRP20120761TT 2006-06-21 2007-06-21 Postupak detekcije i dijagnosticiranja raka koji ukljuäśuje poäśetnice i sonde za specifiäśnu detekciju markera mage-a3 HRP20120761T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0612342.6A GB0612342D0 (en) 2006-06-21 2006-06-21 Method
PCT/EP2007/056219 WO2007147876A2 (en) 2006-06-21 2007-06-21 Method for the detection and diagnosis of cancer involving primers and probes for the specific detection of the mage- a3 -marker

Publications (1)

Publication Number Publication Date
HRP20120761T1 true HRP20120761T1 (hr) 2012-10-31

Family

ID=36803668

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20120761TT HRP20120761T1 (hr) 2006-06-21 2007-06-21 Postupak detekcije i dijagnosticiranja raka koji ukljuäśuje poäśetnice i sonde za specifiäśnu detekciju markera mage-a3

Country Status (27)

Country Link
US (1) US8936919B2 (enExample)
EP (1) EP2041308B1 (enExample)
JP (2) JP2009540812A (enExample)
KR (1) KR101455589B1 (enExample)
CN (1) CN101506383B (enExample)
AU (1) AU2007263019B2 (enExample)
BR (1) BRPI0713599A2 (enExample)
CA (1) CA2656909A1 (enExample)
CO (1) CO6140072A2 (enExample)
CY (1) CY1113290T1 (enExample)
DK (1) DK2041308T3 (enExample)
EA (1) EA016347B1 (enExample)
ES (1) ES2389513T3 (enExample)
GB (1) GB0612342D0 (enExample)
HR (1) HRP20120761T1 (enExample)
IL (1) IL195975A (enExample)
MA (1) MA30565B1 (enExample)
MX (1) MX2008016493A (enExample)
MY (1) MY147511A (enExample)
NO (1) NO20085290L (enExample)
NZ (1) NZ573809A (enExample)
PL (1) PL2041308T3 (enExample)
PT (1) PT2041308E (enExample)
SI (1) SI2041308T1 (enExample)
UA (1) UA95956C2 (enExample)
WO (1) WO2007147876A2 (enExample)
ZA (1) ZA200810695B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101932723B (zh) 2007-09-17 2014-09-10 肿瘤甲基化科学公司 改进的对mage-a表达的检测
CA2805035A1 (en) * 2010-07-22 2012-01-26 Glaxosmithkline Biologicals S.A. Novel antigen binding proteins
CN102251033B (zh) * 2011-07-05 2013-03-20 北京大学人民医院 基于mage-a3基因辅助诊断多发性骨髓瘤患者的定量检测试剂盒

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612201A (en) * 1991-05-23 1997-03-18 Ludwig Institute For Cancer Research Isolated nucleic acid molecules useful in determining expression of a tumor rejection antigen precursor
ATE342730T1 (de) * 1992-08-07 2006-11-15 Pharmexa Inc Hla bindepeptide und ihre verwendungen
DE69524264T2 (de) * 1994-03-01 2002-07-18 Ludwig Institute For Cancer Research, New York Bestimmung krebsartiger beschaffenheiten durch die genexpression eines mitgliedes der melanomartigengruppe, mage
US5985571A (en) * 1998-02-04 1999-11-16 Ludwig Institute For Cancer Research Method for determining multiple myeloma by assaying for expression of mage genes
DE69942214D1 (de) * 1998-02-05 2010-05-12 Glaxosmithkline Biolog Sa Verfahren zur Reinigung oder Herstellung der MAGE Protein
AU5992999A (en) * 1998-10-02 2000-04-26 Ludwig Institute For Cancer Research Tumor antigens and ctl clones isolated by a novel procedure
JP3603138B2 (ja) * 2000-02-18 2004-12-22 独立行政法人理化学研究所 細胞死抑制タンパク質
US6358679B1 (en) * 2000-08-24 2002-03-19 Pe Corporation (Ny) Methods for external controls for nucleic acid amplification
US6635425B2 (en) * 2001-01-05 2003-10-21 Molecular Staging, Inc. 5′-thio phosphate directed ligation of oligonucleotides and use in detection of single nucleotide polymorphisms
JP2005515192A (ja) * 2001-11-29 2005-05-26 ダンドリット バイオテック アクティーゼルスカブ ヒト又は動物において免疫応答を誘導するための医薬組成物
DK2284266T3 (da) 2002-11-14 2014-01-13 Thermo Fisher Scient Biosciences Inc sIRNA-MOLEKYLE MOD TP53
US7910295B2 (en) * 2002-11-14 2011-03-22 John Wayne Cancer Institute Detection of micro metastasis of melanoma and breast cancer in paraffin-embedded tumor draining lymph nodes by multimarker quantitative RT-PCR
GB0409940D0 (en) 2004-05-04 2004-06-09 Glaxosmithkline Biolog Sa Vaccine
US20070231822A1 (en) * 2006-02-28 2007-10-04 Michael Mitas Methods for the detection and treatment of cancer

Also Published As

Publication number Publication date
PT2041308E (pt) 2012-10-09
SI2041308T1 (sl) 2012-10-30
KR20090034900A (ko) 2009-04-08
BRPI0713599A2 (pt) 2012-11-06
GB0612342D0 (en) 2006-08-02
JP2009540812A (ja) 2009-11-26
PL2041308T3 (pl) 2012-11-30
KR101455589B1 (ko) 2014-10-28
EP2041308B1 (en) 2012-07-11
JP2013046630A (ja) 2013-03-07
WO2007147876A2 (en) 2007-12-27
EA200802356A1 (ru) 2009-06-30
MX2008016493A (es) 2009-05-21
AU2007263019A1 (en) 2007-12-27
NZ573809A (en) 2011-12-22
ES2389513T3 (es) 2012-10-26
US8936919B2 (en) 2015-01-20
CY1113290T1 (el) 2016-04-13
UA95956C2 (uk) 2011-09-26
CO6140072A2 (es) 2010-03-19
EA016347B1 (ru) 2012-04-30
CA2656909A1 (en) 2007-12-27
IL195975A0 (en) 2009-09-01
DK2041308T3 (da) 2012-10-08
CN101506383B (zh) 2013-08-28
CN101506383A (zh) 2009-08-12
US20120040341A1 (en) 2012-02-16
WO2007147876A3 (en) 2008-05-15
EP2041308A2 (en) 2009-04-01
HK1127627A1 (en) 2009-10-02
MA30565B1 (fr) 2009-07-01
NO20085290L (no) 2009-01-19
JP5705191B2 (ja) 2015-04-22
ZA200810695B (en) 2014-03-26
AU2007263019B2 (en) 2012-11-08
MY147511A (en) 2012-12-31
IL195975A (en) 2012-08-30

Similar Documents

Publication Publication Date Title
ES2638640T3 (es) Ensayo de HPV RNAscope® para determinar el estado del HPV en los cánceres de cabeza y cuello y en lesiones cervicales
Just et al. Histologic subtypes, immunohistochemistry, FISH or molecular screening for the accurate diagnosis of ALK-rearrangement in lung cancer: a comprehensive study of Caucasian non-smokers
ES2584228T3 (es) Nuevo método de detección para los HPV cervicales
RU2011117297A (ru) Праймеры и зонды для обнаружения вируса папилломы человека и последовательностей бета-глобина человека в исследуемых образцах
JP2012504414A5 (enExample)
RU2017100884A (ru) Набор или устройство для обнаружения рака ободочной и прямой кишки и способ обнаружения
ATE288964T1 (de) Methoden für externe kontrollen zur nukleinsäure amplifizierung
HRP20210198T1 (hr) Postupci detektiranja metiliranja cpg u dna dobivene iz tumora u uzorcima krvi
HRP20100414T1 (hr) Postupak detekcije mutacija egfr u uzorcima krvi
JP2005509445A5 (enExample)
JP2008505644A5 (enExample)
WO2009057294A1 (ja) 肝臓癌関連遺伝子、及び肝臓癌リスクの判定方法
DK1649051T3 (da) Bestemmelse af sekvensen for et polynukleotid
AR077841A1 (es) Metodos kits y composiciones de deteccion de acido nucleico a multiples temperaturas, con sonda unica
ES2575697T3 (es) Métodos y sondas para detectar cáncer de esófago
DE60332775D1 (de) Dopplezweck -Primer und -Proben für verbesserte Hybridisierungsassays durch Zerstörung von Sekundärstrukturen
HRP20120761T1 (hr) Postupak detekcije i dijagnosticiranja raka koji ukljuäśuje poäśetnice i sonde za specifiäśnu detekciju markera mage-a3
GB2422667A (en) Apparatus and methods for fluorescent detection of nucleic acids
ES2601460T3 (es) Materiales y métodos para el diagnóstico del cáncer de vejiga y el control de la recurrencia del mismo
CN105296650B (zh) 一种检测rs9263726等位基因的探针和引物组合物
EP0930369A1 (en) Method for detecting telomerase activity
RU2012113773A (ru) Пробы пептидных нуклеиновых кислот, набор и способ выявления helicobacter pylori и/или его профиля устойчивости, и применения
CN104293932A (zh) 一种基于实时荧光pcr检测hla-b*5801等位基因的方法
CN101457259B (zh) 兰花细菌性褐斑病菌检测用引物和探针及其检测方法
EP1829964A4 (en) METHOD OF STUDYING A SEQUENCE OF A GENE