JP2008505644A5 - - Google Patents
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- JP2008505644A5 JP2008505644A5 JP2007520520A JP2007520520A JP2008505644A5 JP 2008505644 A5 JP2008505644 A5 JP 2008505644A5 JP 2007520520 A JP2007520520 A JP 2007520520A JP 2007520520 A JP2007520520 A JP 2007520520A JP 2008505644 A5 JP2008505644 A5 JP 2008505644A5
- Authority
- JP
- Japan
- Prior art keywords
- mrna species
- specific
- assay
- lymph nodes
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108020004999 messenger RNA Proteins 0.000 claims 43
- 238000000034 method Methods 0.000 claims 41
- 238000003556 assay Methods 0.000 claims 39
- 150000007523 nucleic acids Chemical class 0.000 claims 26
- 210000001165 lymph node Anatomy 0.000 claims 25
- 230000003321 amplification Effects 0.000 claims 24
- 238000003199 nucleic acid amplification method Methods 0.000 claims 24
- 108020004707 nucleic acids Proteins 0.000 claims 23
- 102000039446 nucleic acids Human genes 0.000 claims 23
- 101000998011 Homo sapiens Keratin, type I cytoskeletal 19 Proteins 0.000 claims 18
- 102100033420 Keratin, type I cytoskeletal 19 Human genes 0.000 claims 18
- 101150084967 EPCAM gene Proteins 0.000 claims 17
- 102100031940 Epithelial cell adhesion molecule Human genes 0.000 claims 17
- 101150057140 TACSTD1 gene Proteins 0.000 claims 17
- 101000922002 Conus purpurascens Conotoxin p5a Proteins 0.000 claims 15
- 102100034577 Desmoglein-3 Human genes 0.000 claims 15
- 101000914324 Homo sapiens Carcinoembryonic antigen-related cell adhesion molecule 5 Proteins 0.000 claims 15
- 101000914321 Homo sapiens Carcinoembryonic antigen-related cell adhesion molecule 7 Proteins 0.000 claims 15
- 101000924311 Homo sapiens Desmoglein-3 Proteins 0.000 claims 15
- 101000617725 Homo sapiens Pregnancy-specific beta-1-glycoprotein 2 Proteins 0.000 claims 15
- 101001133631 Lysinibacillus sphaericus Penicillin acylase Proteins 0.000 claims 15
- 210000004027 cell Anatomy 0.000 claims 14
- 102100022019 Pregnancy-specific beta-1-glycoprotein 2 Human genes 0.000 claims 13
- 239000013614 RNA sample Substances 0.000 claims 12
- 101000641959 Homo sapiens Villin-1 Proteins 0.000 claims 10
- 102100033419 Villin-1 Human genes 0.000 claims 10
- 108700020797 Parathyroid Hormone-Related Proteins 0.000 claims 9
- 102000043299 Parathyroid hormone-related Human genes 0.000 claims 9
- 101000994460 Homo sapiens Keratin, type I cytoskeletal 20 Proteins 0.000 claims 8
- 102100032700 Keratin, type I cytoskeletal 20 Human genes 0.000 claims 8
- 101000975502 Homo sapiens Keratin, type II cytoskeletal 7 Proteins 0.000 claims 6
- 102100023974 Keratin, type II cytoskeletal 7 Human genes 0.000 claims 6
- 238000002944 PCR assay Methods 0.000 claims 6
- 238000003757 reverse transcription PCR Methods 0.000 claims 6
- 238000005096 rolling process Methods 0.000 claims 6
- 206010041823 squamous cell carcinoma Diseases 0.000 claims 6
- 239000000523 sample Substances 0.000 claims 5
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 4
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 4
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 4
- 201000004101 esophageal cancer Diseases 0.000 claims 4
- 239000003550 marker Substances 0.000 claims 4
- 201000001441 melanoma Diseases 0.000 claims 4
- 230000001394 metastastic effect Effects 0.000 claims 4
- 206010061289 metastatic neoplasm Diseases 0.000 claims 4
- 102100031672 Homeobox protein CDX-1 Human genes 0.000 claims 3
- 101000777808 Homo sapiens Homeobox protein CDX-1 Proteins 0.000 claims 3
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 3
- 208000000102 Squamous Cell Carcinoma of Head and Neck Diseases 0.000 claims 3
- 201000000459 head and neck squamous cell carcinoma Diseases 0.000 claims 3
- 238000011901 isothermal amplification Methods 0.000 claims 3
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 206010055114 Colon cancer metastatic Diseases 0.000 claims 2
- 101000578784 Homo sapiens Melanoma antigen recognized by T-cells 1 Proteins 0.000 claims 2
- 101001094545 Homo sapiens Retrotransposon-like protein 1 Proteins 0.000 claims 2
- 102100028389 Melanoma antigen recognized by T-cells 1 Human genes 0.000 claims 2
- 208000029742 colonic neoplasm Diseases 0.000 claims 2
- -1 SCCA1.2 Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58659904P | 2004-07-09 | 2004-07-09 | |
| US58701904P | 2004-07-09 | 2004-07-09 | |
| PCT/US2005/024194 WO2006017151A2 (en) | 2004-07-09 | 2005-07-08 | Identification of makers in esophageal cancer, colon cancer, head and neck cancer and melanoma |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011190962A Division JP2012005500A (ja) | 2004-07-09 | 2011-09-01 | 食道癌、結腸癌、頭頸部癌、およびメラノーマにおけるマーカーの同定 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008505644A JP2008505644A (ja) | 2008-02-28 |
| JP2008505644A5 true JP2008505644A5 (enExample) | 2008-08-21 |
Family
ID=35839738
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007520520A Pending JP2008505644A (ja) | 2004-07-09 | 2005-07-08 | 食道癌、結腸癌、頭頸部癌、およびメラノーマにおけるマーカーの同定 |
| JP2007520519A Pending JP2008510454A (ja) | 2004-07-09 | 2005-07-08 | 肺癌および乳癌におけるマーカーの同定 |
| JP2011190962A Withdrawn JP2012005500A (ja) | 2004-07-09 | 2011-09-01 | 食道癌、結腸癌、頭頸部癌、およびメラノーマにおけるマーカーの同定 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007520519A Pending JP2008510454A (ja) | 2004-07-09 | 2005-07-08 | 肺癌および乳癌におけるマーカーの同定 |
| JP2011190962A Withdrawn JP2012005500A (ja) | 2004-07-09 | 2011-09-01 | 食道癌、結腸癌、頭頸部癌、およびメラノーマにおけるマーカーの同定 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US7662561B2 (enExample) |
| EP (6) | EP1774025A4 (enExample) |
| JP (3) | JP2008505644A (enExample) |
| AU (2) | AU2005271960B2 (enExample) |
| CA (2) | CA2571642A1 (enExample) |
| WO (2) | WO2006017150A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050112622A1 (en) | 2003-08-11 | 2005-05-26 | Ring Brian Z. | Reagents and methods for use in cancer diagnosis, classification and therapy |
| US20060003391A1 (en) * | 2003-08-11 | 2006-01-05 | Ring Brian Z | Reagents and methods for use in cancer diagnosis, classification and therapy |
| EP1774025A4 (en) * | 2004-07-09 | 2009-09-16 | Univ Pittsburgh | IDENTIFYING MARKERS IN LUNG AND BREAST CANCER |
| US20080131916A1 (en) * | 2004-08-10 | 2008-06-05 | Ring Brian Z | Reagents and Methods For Use In Cancer Diagnosis, Classification and Therapy |
| JP2008515393A (ja) * | 2004-09-20 | 2008-05-15 | ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | 複数モードの多重化反応消去方法 |
| JP4968577B2 (ja) * | 2006-04-11 | 2012-07-04 | エフ．ホフマン−ラ ロシュ アーゲー | サイトケラチン１９（ＣＫ１９）ｍＲＮＡの迅速測定法、並びにそのためのプライマー及びプローブ |
| US8119352B2 (en) * | 2006-06-20 | 2012-02-21 | Cepheld | Multi-stage amplification reactions by control of sequence replication times |
| JP4943074B2 (ja) * | 2006-07-03 | 2012-05-30 | シスメックス株式会社 | がん転移の判定方法及び装置 |
| US7622456B2 (en) * | 2006-11-06 | 2009-11-24 | Non-Profit Organization Chang Gung Memorial Hospital | Method on clinical applications in head neck cancer by using DSG3 molecule for predicting malignant degree of cancer, serving as a molecular target and using RNA jamming sequence on inhibition-specific of DSG3 expression |
| CA2669600A1 (en) * | 2006-11-13 | 2008-05-29 | Source Precision Medicine, Inc. D/B/A Source Mdx | Gene expression profiling for identification, monitoring, and treatment of lung cancer |
| US9151762B2 (en) | 2009-06-12 | 2015-10-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Identification of DSG-3 as a biomarker for the detection of metastasis in lymph nodes |
| EP2516429B1 (en) | 2009-12-22 | 2020-06-24 | Avon Products, Inc. | Paxillin stimulating compositions and cosmetic uses thereof |
| JP5807877B2 (ja) * | 2009-12-24 | 2015-11-10 | 国立大学法人愛媛大学 | 頸部リンパ節転移分析方法及び頭頸部癌の腫瘍マーカー |
| EP2659004B1 (en) | 2010-12-30 | 2017-08-30 | Avon Products, Inc. | Modulation of dynein in skin |
| US9771617B2 (en) | 2011-06-27 | 2017-09-26 | Eisai R&D Management Co., Ltd. | Microrna biomarkers indicative of alzheimer's disease |
| US10195136B2 (en) | 2011-08-24 | 2019-02-05 | Avon Products, Inc. | Collagen and elastin stimulating compositions and uses thereof |
| US8709507B2 (en) | 2011-12-13 | 2014-04-29 | Avon Products, Inc. | Maesa japonica extracts and methods of use |
| US8632827B2 (en) | 2011-12-13 | 2014-01-21 | Avon Products, Inc | Modulation of thymosin beta-4 in skin |
| JP2013208420A (ja) * | 2012-03-02 | 2013-10-10 | Nippon Koden Corp | 心電図解析レポート、心電図解析装置及び心電図解析プログラム |
| JP6419694B2 (ja) * | 2012-06-29 | 2018-11-07 | デピュイ・シンセス・プロダクツ・インコーポレイテッド | 横方向挿入脊椎インプラント |
| CN108949992B (zh) * | 2018-08-14 | 2021-11-05 | 高鑫 | 一种与食管鳞癌及其分级相关的生物标志物 |
| CN109913552B (zh) * | 2019-03-27 | 2020-08-04 | 河北医科大学第四医院 | 一种食管鳞癌诊疗靶点及应用 |
| EP4116435A1 (en) * | 2021-07-08 | 2023-01-11 | Universidad de Granada | In vitro method for the diagnosis and/or prognosis of malignant melanoma |
| WO2023081988A1 (pt) * | 2021-11-09 | 2023-05-19 | Coelho Guilherme Portela | Método para predição de eficácia de tratamento para câncer de mama |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5274087A (en) | 1986-08-13 | 1993-12-28 | Molecular Diagnostics, Inc. | cDNA coding for carcinoembryonic antigen (CEA) |
| US6379895B1 (en) * | 1989-06-07 | 2002-04-30 | Affymetrix, Inc. | Photolithographic and other means for manufacturing arrays |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US6406844B1 (en) * | 1989-06-07 | 2002-06-18 | Affymetrix, Inc. | Very large scale immobilized polymer synthesis |
| US6040138A (en) | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
| US6346413B1 (en) | 1989-06-07 | 2002-02-12 | Affymetrix, Inc. | Polymer arrays |
| ES2091976T3 (es) * | 1991-06-20 | 1996-11-16 | Hoffmann La Roche | Metodos perfeccionados para la amplificacion del acido nucleico. |
| US6309823B1 (en) | 1993-10-26 | 2001-10-30 | Affymetrix, Inc. | Arrays of nucleic acid probes for analyzing biotransformation genes and methods of using the same |
| EP0732929B1 (en) | 1993-10-29 | 2008-05-14 | The Brigham And Women's Hospital, Inc. | Therapeutic use of cis-element decoys in vivo |
| US7625697B2 (en) * | 1994-06-17 | 2009-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for constructing subarrays and subarrays made thereby |
| AU5310296A (en) | 1995-03-17 | 1996-10-08 | John Wayne Cancer Institute | Detection of melanoma or breast metastases with a multiple marker assay |
| JP4484967B2 (ja) | 1995-06-06 | 2010-06-16 | ベス イスラエル ディーコネス メディカル センター | Ｄｎａ診断試験の方法及び装置 |
| US5882856A (en) | 1995-06-07 | 1999-03-16 | Genzyme Corporation | Universal primer sequence for multiplex DNA amplification |
| US6031129A (en) * | 1995-10-03 | 2000-02-29 | Quantum Chemical Corporation | Use of pentavalent group VA oxides in acetic acid processing |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| US5837442A (en) * | 1995-11-29 | 1998-11-17 | Roche Molecular Systems, Inc. | Oligonucleotide primers for amplifying HCV nucleic acid |
| AUPO188396A0 (en) | 1996-08-26 | 1996-09-19 | Insearch Limited | Detection of protozoan parasites |
| US5958349A (en) | 1997-02-28 | 1999-09-28 | Cepheid | Reaction vessel for heat-exchanging chemical processes |
| US5843721A (en) | 1997-07-03 | 1998-12-01 | Tularik Inc. | Nucleic acids encoding human NIK protein |
| GB9719044D0 (en) | 1997-09-08 | 1997-11-12 | Inst Of Ophthalmology | Assay |
| EP1179585B1 (en) | 1997-12-24 | 2008-07-09 | Cepheid | Device and method for lysis |
| US6660228B1 (en) | 1998-03-02 | 2003-12-09 | Cepheid | Apparatus for performing heat-exchanging, chemical reactions |
| US6037129A (en) * | 1998-05-28 | 2000-03-14 | Medical University Of South Carolina | Multi-marker RT-PCR panel for detecting metastatic breast cancer |
| US6306643B1 (en) | 1998-08-24 | 2001-10-23 | Affymetrix, Inc. | Methods of using an array of pooled probes in genetic analysis |
| US6245517B1 (en) | 1998-09-29 | 2001-06-12 | The United States Of America As Represented By The Department Of Health And Human Services | Ratio-based decisions and the quantitative analysis of cDNA micro-array images |
| US6431476B1 (en) | 1999-12-21 | 2002-08-13 | Cepheid | Apparatus and method for rapid ultrasonic disruption of cells or viruses |
| EP1146869A2 (en) | 1999-01-27 | 2001-10-24 | University Of South Florida | Inhibition of stat3 signal transduction for human cancer therapy |
| US6251601B1 (en) | 1999-02-02 | 2001-06-26 | Vysis, Inc. | Simultaneous measurement of gene expression and genomic abnormalities using nucleic acid microarrays |
| US6300069B1 (en) | 1999-05-03 | 2001-10-09 | Qiagen Gmbh | Generation and amplification of nucleic acids from ribonucleic acids |
| EP1208189B1 (en) | 1999-05-28 | 2004-10-06 | Cepheid | Device and method for analysing liquid samples |
| ATE333938T1 (de) | 1999-05-28 | 2006-08-15 | Cepheid | Patrone zum durchführen einer chemischen reaktion |
| SE9902410D0 (sv) | 1999-06-24 | 1999-06-24 | Cavidi Tech Ab | Reverse transcriptase assay kit, use thereof and method for analysis of RT activity in biological samples |
| AU5830400A (en) * | 1999-06-30 | 2001-01-22 | Arto Orpana | Diagnostic method for squamous cell carcinoma |
| US6403037B1 (en) | 2000-02-04 | 2002-06-11 | Cepheid | Reaction vessel and temperature control system |
| US6844153B2 (en) * | 2000-03-27 | 2005-01-18 | Thomas Jefferson University | Compositions and methods for identifying and targeting cancer cells of alimentary canal origin |
| US6783934B1 (en) | 2000-05-01 | 2004-08-31 | Cepheid, Inc. | Methods for quantitative analysis of nucleic acid amplification reaction |
| US20020168647A1 (en) * | 2000-08-03 | 2002-11-14 | Tongtong Wang | Compositions and methods for the therapy and diagnosis of head and neck cancer |
| US6374684B1 (en) | 2000-08-25 | 2002-04-23 | Cepheid | Fluid control and processing system |
| US8048386B2 (en) | 2002-02-25 | 2011-11-01 | Cepheid | Fluid processing and control |
| WO2002037113A2 (en) * | 2000-11-03 | 2002-05-10 | Michael Giesing | Clinical and functional validation of targets from disseminated cancer cells |
| US6312929B1 (en) | 2000-12-22 | 2001-11-06 | Cepheid | Compositions and methods enabling a totally internally controlled amplification reaction |
| CA2439402A1 (en) | 2001-03-02 | 2002-09-12 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Pcr method |
| EP1464695A1 (en) | 2001-12-26 | 2004-10-06 | Olympus Corporation | Reaction vessel and reaction vessel holding mechanism |
| US6819027B2 (en) | 2002-03-04 | 2004-11-16 | Cepheid | Method and apparatus for controlling ultrasonic transducer |
| EP2261368A1 (en) * | 2002-03-13 | 2010-12-15 | Genomic Health, Inc. | Gene expression profiling in biopsied tumor tissues |
| CN1659287A (zh) * | 2002-04-05 | 2005-08-24 | 美国政府健康及人类服务部 | 诊断肝癌转移或发病可能性及鉴定治疗靶点的方法 |
| EP1540002A2 (en) * | 2002-09-12 | 2005-06-15 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Method for detection of micro-metastasis |
| US7910295B2 (en) * | 2002-11-14 | 2011-03-22 | John Wayne Cancer Institute | Detection of micro metastasis of melanoma and breast cancer in paraffin-embedded tumor draining lymph nodes by multimarker quantitative RT-PCR |
| US20040101859A1 (en) | 2002-11-25 | 2004-05-27 | Cepheid | Compositions, methods and kits for polynucleotide amplification reactions and microfluidic devices |
| WO2005055804A2 (en) * | 2003-12-02 | 2005-06-23 | Musc Foundation For Research Development | Methods and compositions for diagnosing epithelial cell cancer |
| EP1774025A4 (en) * | 2004-07-09 | 2009-09-16 | Univ Pittsburgh | IDENTIFYING MARKERS IN LUNG AND BREAST CANCER |
| JP2008515393A (ja) * | 2004-09-20 | 2008-05-15 | ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | 複数モードの多重化反応消去方法 |
| US9032602B2 (en) | 2011-07-15 | 2015-05-19 | The Boeing Company | Methods and systems for in-process quality control during drill-fill assembly |
-
2005
- 2005-07-08 EP EP05764654A patent/EP1774025A4/en not_active Ceased
- 2005-07-08 CA CA002571642A patent/CA2571642A1/en not_active Abandoned
- 2005-07-08 EP EP10183722A patent/EP2287329A3/en not_active Withdrawn
- 2005-07-08 WO PCT/US2005/024193 patent/WO2006017150A2/en not_active Ceased
- 2005-07-08 AU AU2005271960A patent/AU2005271960B2/en not_active Ceased
- 2005-07-08 JP JP2007520520A patent/JP2008505644A/ja active Pending
- 2005-07-08 EP EP05770149A patent/EP1774030A4/en not_active Withdrawn
- 2005-07-08 EP EP10183644A patent/EP2272987A3/en not_active Withdrawn
- 2005-07-08 JP JP2007520519A patent/JP2008510454A/ja active Pending
- 2005-07-08 US US11/178,134 patent/US7662561B2/en not_active Expired - Fee Related
- 2005-07-08 EP EP12151990A patent/EP2468889A3/en not_active Withdrawn
- 2005-07-08 US US11/178,109 patent/US20060068418A1/en not_active Abandoned
- 2005-07-08 WO PCT/US2005/024194 patent/WO2006017151A2/en not_active Ceased
- 2005-07-08 EP EP10183750A patent/EP2275578A3/en not_active Withdrawn
- 2005-07-08 CA CA002571650A patent/CA2571650A1/en not_active Abandoned
- 2005-07-08 AU AU2005271961A patent/AU2005271961B8/en not_active Ceased
-
2009
- 2009-12-15 US US12/637,862 patent/US20100240037A1/en not_active Abandoned
-
2011
- 2011-02-17 US US13/030,003 patent/US20110312515A1/en not_active Abandoned
- 2011-09-01 JP JP2011190962A patent/JP2012005500A/ja not_active Withdrawn
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