SI2041308T1 - Postopek za detekcijo in diagnozo raka, ki vključuje primerje in sonde za specifično detekcijo markerja MAGE-A3 - Google Patents

Postopek za detekcijo in diagnozo raka, ki vključuje primerje in sonde za specifično detekcijo markerja MAGE-A3

Info

Publication number
SI2041308T1
SI2041308T1 SI200731011T SI200731011T SI2041308T1 SI 2041308 T1 SI2041308 T1 SI 2041308T1 SI 200731011 T SI200731011 T SI 200731011T SI 200731011 T SI200731011 T SI 200731011T SI 2041308 T1 SI2041308 T1 SI 2041308T1
Authority
SI
Slovenia
Prior art keywords
detection
mage
probes
marker
diagnosis
Prior art date
Application number
SI200731011T
Other languages
English (en)
Slovenian (sl)
Inventor
Thierry Coche
Olivier Gruselle
Gabriele Anne-Marie Beer
Dennis Salonga
Craig Lawrence Stephens
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of SI2041308T1 publication Critical patent/SI2041308T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0091—Purification or manufacturing processes for gene therapy compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Manufacturing & Machinery (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SI200731011T 2006-06-21 2007-06-21 Postopek za detekcijo in diagnozo raka, ki vključuje primerje in sonde za specifično detekcijo markerja MAGE-A3 SI2041308T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0612342.6A GB0612342D0 (en) 2006-06-21 2006-06-21 Method
PCT/EP2007/056219 WO2007147876A2 (en) 2006-06-21 2007-06-21 Method for the detection and diagnosis of cancer involving primers and probes for the specific detection of the mage- a3 -marker
EP07786793A EP2041308B1 (en) 2006-06-21 2007-06-21 Method for the detection and diagnosis of cancer involving primers and probes for the specific detection of the mage-a3 marker

Publications (1)

Publication Number Publication Date
SI2041308T1 true SI2041308T1 (sl) 2012-10-30

Family

ID=36803668

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200731011T SI2041308T1 (sl) 2006-06-21 2007-06-21 Postopek za detekcijo in diagnozo raka, ki vključuje primerje in sonde za specifično detekcijo markerja MAGE-A3

Country Status (27)

Country Link
US (1) US8936919B2 (enExample)
EP (1) EP2041308B1 (enExample)
JP (2) JP2009540812A (enExample)
KR (1) KR101455589B1 (enExample)
CN (1) CN101506383B (enExample)
AU (1) AU2007263019B2 (enExample)
BR (1) BRPI0713599A2 (enExample)
CA (1) CA2656909A1 (enExample)
CO (1) CO6140072A2 (enExample)
CY (1) CY1113290T1 (enExample)
DK (1) DK2041308T3 (enExample)
EA (1) EA016347B1 (enExample)
ES (1) ES2389513T3 (enExample)
GB (1) GB0612342D0 (enExample)
HR (1) HRP20120761T1 (enExample)
IL (1) IL195975A (enExample)
MA (1) MA30565B1 (enExample)
MX (1) MX2008016493A (enExample)
MY (1) MY147511A (enExample)
NO (1) NO20085290L (enExample)
NZ (1) NZ573809A (enExample)
PL (1) PL2041308T3 (enExample)
PT (1) PT2041308E (enExample)
SI (1) SI2041308T1 (enExample)
UA (1) UA95956C2 (enExample)
WO (1) WO2007147876A2 (enExample)
ZA (1) ZA200810695B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101932723B (zh) 2007-09-17 2014-09-10 肿瘤甲基化科学公司 改进的对mage-a表达的检测
CA2805035A1 (en) * 2010-07-22 2012-01-26 Glaxosmithkline Biologicals S.A. Novel antigen binding proteins
CN102251033B (zh) * 2011-07-05 2013-03-20 北京大学人民医院 基于mage-a3基因辅助诊断多发性骨髓瘤患者的定量检测试剂盒

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612201A (en) * 1991-05-23 1997-03-18 Ludwig Institute For Cancer Research Isolated nucleic acid molecules useful in determining expression of a tumor rejection antigen precursor
ATE342730T1 (de) * 1992-08-07 2006-11-15 Pharmexa Inc Hla bindepeptide und ihre verwendungen
DE69524264T2 (de) * 1994-03-01 2002-07-18 Ludwig Institute For Cancer Research, New York Bestimmung krebsartiger beschaffenheiten durch die genexpression eines mitgliedes der melanomartigengruppe, mage
US5985571A (en) * 1998-02-04 1999-11-16 Ludwig Institute For Cancer Research Method for determining multiple myeloma by assaying for expression of mage genes
DE69942214D1 (de) * 1998-02-05 2010-05-12 Glaxosmithkline Biolog Sa Verfahren zur Reinigung oder Herstellung der MAGE Protein
AU5992999A (en) * 1998-10-02 2000-04-26 Ludwig Institute For Cancer Research Tumor antigens and ctl clones isolated by a novel procedure
JP3603138B2 (ja) * 2000-02-18 2004-12-22 独立行政法人理化学研究所 細胞死抑制タンパク質
US6358679B1 (en) * 2000-08-24 2002-03-19 Pe Corporation (Ny) Methods for external controls for nucleic acid amplification
US6635425B2 (en) * 2001-01-05 2003-10-21 Molecular Staging, Inc. 5′-thio phosphate directed ligation of oligonucleotides and use in detection of single nucleotide polymorphisms
JP2005515192A (ja) * 2001-11-29 2005-05-26 ダンドリット バイオテック アクティーゼルスカブ ヒト又は動物において免疫応答を誘導するための医薬組成物
DK2284266T3 (da) 2002-11-14 2014-01-13 Thermo Fisher Scient Biosciences Inc sIRNA-MOLEKYLE MOD TP53
US7910295B2 (en) * 2002-11-14 2011-03-22 John Wayne Cancer Institute Detection of micro metastasis of melanoma and breast cancer in paraffin-embedded tumor draining lymph nodes by multimarker quantitative RT-PCR
GB0409940D0 (en) 2004-05-04 2004-06-09 Glaxosmithkline Biolog Sa Vaccine
US20070231822A1 (en) * 2006-02-28 2007-10-04 Michael Mitas Methods for the detection and treatment of cancer

Also Published As

Publication number Publication date
PT2041308E (pt) 2012-10-09
KR20090034900A (ko) 2009-04-08
BRPI0713599A2 (pt) 2012-11-06
GB0612342D0 (en) 2006-08-02
JP2009540812A (ja) 2009-11-26
PL2041308T3 (pl) 2012-11-30
KR101455589B1 (ko) 2014-10-28
EP2041308B1 (en) 2012-07-11
JP2013046630A (ja) 2013-03-07
WO2007147876A2 (en) 2007-12-27
EA200802356A1 (ru) 2009-06-30
MX2008016493A (es) 2009-05-21
AU2007263019A1 (en) 2007-12-27
NZ573809A (en) 2011-12-22
ES2389513T3 (es) 2012-10-26
US8936919B2 (en) 2015-01-20
CY1113290T1 (el) 2016-04-13
UA95956C2 (uk) 2011-09-26
CO6140072A2 (es) 2010-03-19
EA016347B1 (ru) 2012-04-30
CA2656909A1 (en) 2007-12-27
IL195975A0 (en) 2009-09-01
DK2041308T3 (da) 2012-10-08
CN101506383B (zh) 2013-08-28
CN101506383A (zh) 2009-08-12
US20120040341A1 (en) 2012-02-16
HRP20120761T1 (hr) 2012-10-31
WO2007147876A3 (en) 2008-05-15
EP2041308A2 (en) 2009-04-01
HK1127627A1 (en) 2009-10-02
MA30565B1 (fr) 2009-07-01
NO20085290L (no) 2009-01-19
JP5705191B2 (ja) 2015-04-22
ZA200810695B (en) 2014-03-26
AU2007263019B2 (en) 2012-11-08
MY147511A (en) 2012-12-31
IL195975A (en) 2012-08-30

Similar Documents

Publication Publication Date Title
WO2011008262A9 (en) Methods and apparatus for diagnosis and/or prognosis of cancer
EP2016394A4 (en) METHOD AND COMPOSITIONS FOR HIGHLY SENSITIVE ANALYSIS OF MARKERS AND DETECTION OF MOLECULES
IL218021A0 (en) Methods, primers, probes and kits useful for the detection of braf mutations
IL192790A0 (en) Method and markers for the diagnosis of renal diseases
PT3106874T (pt) Método para a deteção de cancro
HU0700807D0 (en) Arrangement and method for detection and/or measurement of respiration
PL2140269T3 (pl) Podpis białkowy/znaczniki do wykrywania gruczolakoraka
EP2406613A4 (en) METHOD AND SYSTEM FOR MEASURING / DETECTING CHEMICAL LEAVES
EP2115458A4 (en) METHOD FOR DIAGNOSIS OF HEALTH CONDITIONS FOR OVARIAL CARCINOMA AND THE RISK OF HEALTH CONDITIONS IN OVARIAL CARCINOMA
ZA200808669B (en) Methods of treating, diagnosing or detecting cancer
EP2011871A4 (en) PRIMER AND PROBE FOR THE DETECTION OF MYCOBACTERIUM INTRACELLULARE AND METHOD FOR THE DETECTION OF MYCOBACTERIUM INTRACELLULARE USING THE PRIMER AND THE PROBE
GB0915869D0 (en) Composition and assay method for the detection of patogenic bacteria
EP2192182A4 (en) PRIMERSET AND PROBE TO DETECT HUMAN PAPILLOMA VIRUS
EP1937816A4 (en) CANCER DIAGNOSTIC MARKERS AND USE
ZA200904558B (en) Detection of analytes
IL195975A0 (en) Method for the detection and diagnosis of cancer involving primers and probes for the specific detection of the mage-a3 marker
WO2011044513A9 (en) Diagnostic and prognostic markers for cancer
EP2284262A4 (en) PRIMER AND PROBE FOR DETECTION OF MYCOBACTERIUM INTRACELLULARE, AND METHOD FOR DETECTION OF MYCOBACTERIUM INTRACELLULARE USING THE PRIMER OR PROBE
EP2212874A4 (en) DEVICE FOR MONITORING AND LOCATING SEMI-TRAILERS
GB2434447B (en) Fluorescent probe for the detection of corrosion
EP2176637A4 (en) MOUTH CANCER MARKERS AND THEIR DETECTION
EP1914318A4 (en) METHOD FOR DETECTING THICK-ARMED CANCER MARKERS
CR10532A (es) Method for the detection and diagnosis of cancer involving primers and probes for the specific detection of the mage- a3- marker
EP1974213A4 (en) HIGHLY SENSITIVE SECRETAGOGIN ASSAYS AND ITS USE IN DIAGNOSIS AND / OR FORECASTING
IL192875A0 (en) Marker and method for cancer diagnosis