MX2008016493A - Metodo para la deteccion de diagnostico de cancer que implica cebadores y sondas para la deteccion especifica del marcador mage-3. - Google Patents

Metodo para la deteccion de diagnostico de cancer que implica cebadores y sondas para la deteccion especifica del marcador mage-3.

Info

Publication number
MX2008016493A
MX2008016493A MX2008016493A MX2008016493A MX2008016493A MX 2008016493 A MX2008016493 A MX 2008016493A MX 2008016493 A MX2008016493 A MX 2008016493A MX 2008016493 A MX2008016493 A MX 2008016493A MX 2008016493 A MX2008016493 A MX 2008016493A
Authority
MX
Mexico
Prior art keywords
detection
mage
probes
marker
diagnosis
Prior art date
Application number
MX2008016493A
Other languages
English (en)
Inventor
Thierry Coche
Olivier Gruselle
Gabriele Annemarie Beer
Dennis Salonga
Craig Lawrence Stephens
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of MX2008016493A publication Critical patent/MX2008016493A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0091Purification or manufacturing processes for gene therapy compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Manufacturing & Machinery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se refiere a cebadores y sondas específicos de MAGE-A3 para utilizar equipos y métodos de diagnóstico nuevos. La presente invención se refiere además al tratamiento inmunoterapéutico de poblaciones específicas de pacientes con cáncer, que padecen de tumores que expresan MAGE-A3.
MX2008016493A 2006-06-21 2007-06-21 Metodo para la deteccion de diagnostico de cancer que implica cebadores y sondas para la deteccion especifica del marcador mage-3. MX2008016493A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0612342.6A GB0612342D0 (en) 2006-06-21 2006-06-21 Method
PCT/EP2007/056219 WO2007147876A2 (en) 2006-06-21 2007-06-21 Method for the detection and diagnosis of cancer involving primers and probes for the specific detection of the mage- a3 -marker

Publications (1)

Publication Number Publication Date
MX2008016493A true MX2008016493A (es) 2009-05-21

Family

ID=36803668

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008016493A MX2008016493A (es) 2006-06-21 2007-06-21 Metodo para la deteccion de diagnostico de cancer que implica cebadores y sondas para la deteccion especifica del marcador mage-3.

Country Status (28)

Country Link
US (1) US8936919B2 (es)
EP (1) EP2041308B1 (es)
JP (2) JP2009540812A (es)
KR (1) KR101455589B1 (es)
CN (1) CN101506383B (es)
AU (1) AU2007263019B2 (es)
BR (1) BRPI0713599A2 (es)
CA (1) CA2656909A1 (es)
CO (1) CO6140072A2 (es)
CY (1) CY1113290T1 (es)
DK (1) DK2041308T3 (es)
EA (1) EA016347B1 (es)
ES (1) ES2389513T3 (es)
GB (1) GB0612342D0 (es)
HK (1) HK1127627A1 (es)
HR (1) HRP20120761T1 (es)
IL (1) IL195975A (es)
MA (1) MA30565B1 (es)
MX (1) MX2008016493A (es)
MY (1) MY147511A (es)
NO (1) NO20085290L (es)
NZ (1) NZ573809A (es)
PL (1) PL2041308T3 (es)
PT (1) PT2041308E (es)
SI (1) SI2041308T1 (es)
UA (1) UA95956C2 (es)
WO (1) WO2007147876A2 (es)
ZA (1) ZA200810695B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ583796A (en) 2007-09-17 2011-12-22 Oncomethylome Sciences Sa Improved detection of mage-a expression
BR112013001637A2 (pt) * 2010-07-22 2016-05-24 Glaxosmithkline Biolog Sa proteína ligadora de antígeno, molécula de ácido nucleico, vetor de expressão, célula hospedeira recombinante, métodos para produção de proteína ligadora de antígeno, e para detectar mage-a3 e/ou mage-a6 em tecido de humano fixado com formalina e infiltrado em parafina.
CN102251033B (zh) * 2011-07-05 2013-03-20 北京大学人民医院 基于mage-a3基因辅助诊断多发性骨髓瘤患者的定量检测试剂盒

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612201A (en) * 1991-05-23 1997-03-18 Ludwig Institute For Cancer Research Isolated nucleic acid molecules useful in determining expression of a tumor rejection antigen precursor
IL106610A0 (en) * 1992-08-07 1993-12-08 Cytel Corp Hla binding peptides and their uses
CA2184482A1 (en) * 1994-03-01 1995-09-08 Etienne De Plaen Determination of cancerous conditions by mage gene expression
US5985571A (en) 1998-02-04 1999-11-16 Ludwig Institute For Cancer Research Method for determining multiple myeloma by assaying for expression of mage genes
BR9907691B1 (pt) * 1998-02-05 2011-05-31 derivado de antìgeno e antìgeno da famìlia mage associado a tumor, seqüência de ácido nucléico, codificando os mesmos, seus usos na preparação de vacina, processo para produção de vacina e vacina.
WO2000020445A2 (en) * 1998-10-02 2000-04-13 Ludwig Institute For Cancer Research Tumor antigens and ctl clones isolated by a novel procedure
JP3603138B2 (ja) * 2000-02-18 2004-12-22 独立行政法人理化学研究所 細胞死抑制タンパク質
US6358679B1 (en) * 2000-08-24 2002-03-19 Pe Corporation (Ny) Methods for external controls for nucleic acid amplification
US6635425B2 (en) * 2001-01-05 2003-10-21 Molecular Staging, Inc. 5′-thio phosphate directed ligation of oligonucleotides and use in detection of single nucleotide polymorphisms
WO2003045427A2 (en) * 2001-11-29 2003-06-05 Dandrit Biotech A/S Pharmaceutical composition for inducing an immune response in a human or animal
DK2284266T3 (da) 2002-11-14 2014-01-13 Thermo Fisher Scient Biosciences Inc sIRNA-MOLEKYLE MOD TP53
AU2003290925A1 (en) * 2002-11-14 2004-06-15 John Wayne Cancer Institute Detection of micro metastasis of melanoma and breast cancer in paraffin-embedded tumor draining lymph nodes by multimaker quantitative rt-pcr
GB0409940D0 (en) * 2004-05-04 2004-06-09 Glaxosmithkline Biolog Sa Vaccine
US20070231822A1 (en) * 2006-02-28 2007-10-04 Michael Mitas Methods for the detection and treatment of cancer

Also Published As

Publication number Publication date
US20120040341A1 (en) 2012-02-16
UA95956C2 (uk) 2011-09-26
PL2041308T3 (pl) 2012-11-30
GB0612342D0 (en) 2006-08-02
AU2007263019A1 (en) 2007-12-27
EA200802356A1 (ru) 2009-06-30
WO2007147876A2 (en) 2007-12-27
WO2007147876A3 (en) 2008-05-15
NZ573809A (en) 2011-12-22
HRP20120761T1 (hr) 2012-10-31
KR20090034900A (ko) 2009-04-08
JP5705191B2 (ja) 2015-04-22
EP2041308A2 (en) 2009-04-01
JP2009540812A (ja) 2009-11-26
SI2041308T1 (sl) 2012-10-30
HK1127627A1 (en) 2009-10-02
CO6140072A2 (es) 2010-03-19
IL195975A (en) 2012-08-30
ES2389513T3 (es) 2012-10-26
JP2013046630A (ja) 2013-03-07
MA30565B1 (fr) 2009-07-01
CN101506383A (zh) 2009-08-12
ZA200810695B (en) 2014-03-26
CN101506383B (zh) 2013-08-28
IL195975A0 (en) 2009-09-01
PT2041308E (pt) 2012-10-09
CA2656909A1 (en) 2007-12-27
EA016347B1 (ru) 2012-04-30
NO20085290L (no) 2009-01-19
DK2041308T3 (da) 2012-10-08
US8936919B2 (en) 2015-01-20
AU2007263019B2 (en) 2012-11-08
EP2041308B1 (en) 2012-07-11
KR101455589B1 (ko) 2014-10-28
MY147511A (en) 2012-12-31
CY1113290T1 (el) 2016-04-13
BRPI0713599A2 (pt) 2012-11-06

Similar Documents

Publication Publication Date Title
AU2008298744A8 (en) MiRNA expression in human peripheral blood microvesicles and uses thereof
MX2013002084A (es) Biomarcadores y metodos de tratamiento.
WO2007140958A3 (en) Method for identifying whether a patient will be responder or not to immunotherapy
MX2009012722A (es) Variantes geneticas sobre chr 5p12 y 10q26 como marcadores para el uso en la evaluacion del riesgo, diagnostico, pronostico y tratamiento del cancer de mama.
EP3683320A3 (en) Mirna fingerprint in the diagnosis of lung cancer
WO2012006589A3 (en) Methods and compositions for identification, assessment and treatment of cancers associated with hedgehog signaling
WO2007016548A3 (en) Micro-rna-based methods and compositions for the diagnosis, prognosis and treatment of breast cancer
MX2009012625A (es) Metodos para el tratamiento, diagnostico y deteccion de trastornos asociados con el fgf21.
EP2179037A4 (en) DIAGNOSIS, FORECASTING AND TREATMENT PROCEDURES
WO2007081680A3 (en) Microrna expression abnormalities in pancreatic endocrine and acinar tumors
MX2010000405A (es) Seleccion de farmacos para terapia de cancer de pulmon usando arreglos a base de anticuerpos.
AU2011260390A8 (en) Means and methods for diagnosing pancreatic cancer in a subject
WO2012068383A3 (en) ncRNA AND USES THEREOF
MX2009010439A (es) Variantes geneticas de chr2 y chr16 como marcadores para el uso en valoracion, diagnosis, prognosis y tratamiento de riesgo de cancer de mama.
MX340724B (es) Terapia anti-angiogenesis para el tratamiento del cancer de mama.
WO2010091049A3 (en) Diagnosis and treatment of cancer
MX2013011431A (es) Metodos para predecir y mejorar la supervivencia de pacientes con cancer gastrico.
MX2009013649A (es) Variantes geneticas en el cromosoma 15q24 como marcadores para usarse en diagnostico, prognosis y tratamiento de sindrome de exfoliacion y glaucoma.
MX2015000008A (es) Uso de marcadores en el diagnostico y tratamiento de cancer de prostata.
WO2007123722A3 (en) Methods for prediction and prognosis of cancer, and monitoring cancer therapy
WO2010101793A3 (en) Methods and compositions for the diagnosis, prognosis and treatment of cancer
WO2011093675A3 (ko) 혈액으로부터 직접 폐암 진단 및 폐암의 서브타입 진단이 가능한 마커를 선별하는 시스템 생물학적 방법 및 이로부터 선별된 혈액으로부터 직접 폐암 진단 및 폐암 서브타입 진단이 가능한 마커
IN2012DN01979A (es)
WO2010028373A3 (en) Methods for diagnosing cancer and determining the overall survival and disease-free survival of cancer patients
SG179129A1 (en) Method for identifying whether a patient will be responder or not to immunotherapy

Legal Events

Date Code Title Description
HH Correction or change in general
FG Grant or registration