ES2575697T3 - Métodos y sondas para detectar cáncer de esófago - Google Patents

Métodos y sondas para detectar cáncer de esófago Download PDF

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Publication number
ES2575697T3
ES2575697T3 ES12178901.0T ES12178901T ES2575697T3 ES 2575697 T3 ES2575697 T3 ES 2575697T3 ES 12178901 T ES12178901 T ES 12178901T ES 2575697 T3 ES2575697 T3 ES 2575697T3
Authority
ES
Spain
Prior art keywords
probes
locus
precursor lesion
esophageal carcinoma
specific probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES12178901.0T
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English (en)
Inventor
Kevin Halling
Larry E Morrison
Shannon Brankley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mayo Foundation for Medical Education and Research
Abbott Molecular Inc
Mayo Clinic in Florida
Original Assignee
Mayo Foundation for Medical Education and Research
Abbott Molecular Inc
Mayo Clinic in Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayo Foundation for Medical Education and Research, Abbott Molecular Inc, Mayo Clinic in Florida filed Critical Mayo Foundation for Medical Education and Research
Application granted granted Critical
Publication of ES2575697T3 publication Critical patent/ES2575697T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Un método para la detección de un carcinoma de esófago o una lesión precursora en un sujeto, en donde el carcinoma o la lesión precursora detectado selectivamente se selecciona del grupo que consiste en displasia de alto grado (DAG) y adenocarcinoma de esófago (AE), comprendiendo el método: a) poner en contacto una muestra biológica que comprende células del esófago procedentes del sujeto del que se sospecha que tiene un carcinoma de esófago con un conjunto de sondas cromosómicas para detectar selectivamente un carcinoma de esófago o una lesión precursora en la muestra, si la hubiera, en condiciones para hibridar específicamente las sondas a sus ácidos nucleicos diana presentes en la muestra; en donde dicho conjunto consiste en una sonda específica del locus 20q13, una sonda de recuento cromosómico del cromosoma 9, una sonda específica del locus 7p12, una sonda específica del locus 5q21-22; y b) detectar un patrón de hibridación para el conjunto de sondas cromosómicas con la muestra biológica, en donde el patrón de hibridación es indicativo de la presencia o ausencia de un carcinoma de esófago o de una lesión precursora.

Description

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20
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ES12178901.0T 2005-02-18 2006-02-17 Métodos y sondas para detectar cáncer de esófago Expired - Lifetime ES2575697T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65474205P 2005-02-18 2005-02-18
US654742P 2005-02-18

Publications (1)

Publication Number Publication Date
ES2575697T3 true ES2575697T3 (es) 2016-06-30

Family

ID=36917111

Family Applications (3)

Application Number Title Priority Date Filing Date
ES12178901.0T Expired - Lifetime ES2575697T3 (es) 2005-02-18 2006-02-17 Métodos y sondas para detectar cáncer de esófago
ES06735413.4T Expired - Lifetime ES2528382T3 (es) 2005-02-18 2006-02-17 Métodos y sondas para detectar cáncer de esófago
ES14176615.4T Expired - Lifetime ES2644641T3 (es) 2005-02-18 2006-02-17 Métodos y sondas para detectar cáncer de esófago

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES06735413.4T Expired - Lifetime ES2528382T3 (es) 2005-02-18 2006-02-17 Métodos y sondas para detectar cáncer de esófago
ES14176615.4T Expired - Lifetime ES2644641T3 (es) 2005-02-18 2006-02-17 Métodos y sondas para detectar cáncer de esófago

Country Status (6)

Country Link
US (2) US8034577B2 (es)
EP (4) EP2540842B8 (es)
JP (4) JP2008537097A (es)
CA (1) CA2598006C (es)
ES (3) ES2575697T3 (es)
WO (1) WO2006089163A2 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070059747A1 (en) * 2005-09-02 2007-03-15 Regents Of The University Of California Methods and probe combinations for detecting melanoma
JP5457673B2 (ja) 2005-09-20 2014-04-02 ベリデックス・リミテッド・ライアビリティ・カンパニー ユニーク配列のｄｎａプローブを作製するための方法および組成物、ｄｎａプローブの標識、ならびにこれらプローブの使用
EP3153860A3 (en) 2005-12-22 2017-06-14 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
US20080133141A1 (en) * 2005-12-22 2008-06-05 Frost Stephen J Weighted Scoring Methods and Use Thereof in Screening
US9347945B2 (en) 2005-12-22 2016-05-24 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
US7960110B2 (en) * 2006-11-15 2011-06-14 The Regents Of The University Of California Detection of chromosomal region copy number changes to diagnose melanoma
US8679759B2 (en) * 2007-08-01 2014-03-25 The Johns Hopkins University Esophageal cancer markers
WO2012162610A1 (en) 2011-05-26 2012-11-29 Adn International, Llc Expandable device for tissue collection from an aerodigestive body lumen
EP3272882B1 (en) * 2011-09-23 2019-02-20 Academisch Medisch Centrum Materials and methods for prognosis of progression of barrett's esophagus
US10255410B2 (en) * 2011-12-01 2019-04-09 Interpace Diagnostics Corporation Methods for treating Barrett's metaplasia and esophageal adenocarcinoma
US10131942B2 (en) 2011-12-01 2018-11-20 Interpace Diagnostics Corporation Methods for treating barrett's metaplasia and esophageal adenocarcinoma
EP2847593A4 (en) * 2012-05-11 2016-01-13 Hutchinson Fred Cancer Res METHODS FOR PREDICTING AND DETECTING THE RISK OF CANCER
AU2014346735A1 (en) * 2013-11-07 2016-06-09 Cellay, Inc. Methods and kits for detecting a prostate carcinoma and predicting disease outcomes for prostate cancers
ES2702603T3 (es) 2015-06-23 2019-03-04 Zytovision Gmbh Procedimiento para la detección de aberraciones cromosómicas
AU2020283954B2 (en) * 2019-05-28 2026-04-30 Case Western Reserve University Compositions and methods for preserving DNA methylation
WO2021242872A1 (en) 2020-05-27 2021-12-02 Case Western Reserve University Compositions and methods for preserving dna methylation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US617468A (en) 1899-01-10 miller
US5756696A (en) 1986-01-16 1998-05-26 Regents Of The University Of California Compositions for chromosome-specific staining
US5491224A (en) 1990-09-20 1996-02-13 Bittner; Michael L. Direct label transaminated DNA probe compositions for chromosome identification and methods for their manufacture
US6174681B1 (en) 1999-03-05 2001-01-16 Mayo Foundation For Medical Education And Research Method and probe set for detecting cancer
US20030087248A1 (en) * 2001-02-20 2003-05-08 Morrison Larry E. Methods and probes for the detection of cancer

Also Published As

Publication number Publication date
EP2789697B1 (en) 2017-07-19
JP6371252B2 (ja) 2018-08-08
WO2006089163A3 (en) 2009-06-04
EP2789697A2 (en) 2014-10-15
EP1853729B1 (en) 2014-12-03
WO2006089163A2 (en) 2006-08-24
ES2644641T3 (es) 2017-11-29
EP1853729A2 (en) 2007-11-14
CA2598006A1 (en) 2006-08-24
EP2540842B1 (en) 2016-04-06
JP2015165807A (ja) 2015-09-24
EP2540842A3 (en) 2013-04-03
US8034577B2 (en) 2011-10-11
EP3246417B1 (en) 2019-09-11
JP2019213542A (ja) 2019-12-19
EP2540842B8 (en) 2016-06-01
US20060211019A1 (en) 2006-09-21
CA2598006C (en) 2018-12-11
EP1853729A4 (en) 2010-05-05
JP6662813B2 (ja) 2020-03-11
EP2789697A3 (en) 2015-01-21
EP3246417A1 (en) 2017-11-22
JP2017205119A (ja) 2017-11-24
ES2528382T3 (es) 2015-02-09
JP2008537097A (ja) 2008-09-11
US20120141991A1 (en) 2012-06-07
EP2540842A2 (en) 2013-01-02

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