ES2575697T3 - Métodos y sondas para detectar cáncer de esófago - Google Patents
Métodos y sondas para detectar cáncer de esófago Download PDFInfo
- Publication number
- ES2575697T3 ES2575697T3 ES12178901.0T ES12178901T ES2575697T3 ES 2575697 T3 ES2575697 T3 ES 2575697T3 ES 12178901 T ES12178901 T ES 12178901T ES 2575697 T3 ES2575697 T3 ES 2575697T3
- Authority
- ES
- Spain
- Prior art keywords
- probes
- locus
- precursor lesion
- esophageal carcinoma
- specific probe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
Un método para la detección de un carcinoma de esófago o una lesión precursora en un sujeto, en donde el carcinoma o la lesión precursora detectado selectivamente se selecciona del grupo que consiste en displasia de alto grado (DAG) y adenocarcinoma de esófago (AE), comprendiendo el método: a) poner en contacto una muestra biológica que comprende células del esófago procedentes del sujeto del que se sospecha que tiene un carcinoma de esófago con un conjunto de sondas cromosómicas para detectar selectivamente un carcinoma de esófago o una lesión precursora en la muestra, si la hubiera, en condiciones para hibridar específicamente las sondas a sus ácidos nucleicos diana presentes en la muestra; en donde dicho conjunto consiste en una sonda específica del locus 20q13, una sonda de recuento cromosómico del cromosoma 9, una sonda específica del locus 7p12, una sonda específica del locus 5q21-22; y b) detectar un patrón de hibridación para el conjunto de sondas cromosómicas con la muestra biológica, en donde el patrón de hibridación es indicativo de la presencia o ausencia de un carcinoma de esófago o de una lesión precursora.
Description
16
20
21
30
32
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65474205P | 2005-02-18 | 2005-02-18 | |
US654742P | 2005-02-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2575697T3 true ES2575697T3 (es) | 2016-06-30 |
Family
ID=36917111
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES06735413.4T Active ES2528382T3 (es) | 2005-02-18 | 2006-02-17 | Métodos y sondas para detectar cáncer de esófago |
ES14176615.4T Active ES2644641T3 (es) | 2005-02-18 | 2006-02-17 | Métodos y sondas para detectar cáncer de esófago |
ES12178901.0T Active ES2575697T3 (es) | 2005-02-18 | 2006-02-17 | Métodos y sondas para detectar cáncer de esófago |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES06735413.4T Active ES2528382T3 (es) | 2005-02-18 | 2006-02-17 | Métodos y sondas para detectar cáncer de esófago |
ES14176615.4T Active ES2644641T3 (es) | 2005-02-18 | 2006-02-17 | Métodos y sondas para detectar cáncer de esófago |
Country Status (6)
Country | Link |
---|---|
US (2) | US8034577B2 (es) |
EP (4) | EP3246417B1 (es) |
JP (4) | JP2008537097A (es) |
CA (1) | CA2598006C (es) |
ES (3) | ES2528382T3 (es) |
WO (1) | WO2006089163A2 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007028031A2 (en) * | 2005-09-02 | 2007-03-08 | The Regents Of The University Of California | Methods and probe combinations for detecting melanoma |
JP5457673B2 (ja) * | 2005-09-20 | 2014-04-02 | ベリデックス・リミテッド・ライアビリティ・カンパニー | ユニーク配列のdnaプローブを作製するための方法および組成物、dnaプローブの標識、ならびにこれらプローブの使用 |
US20080133141A1 (en) * | 2005-12-22 | 2008-06-05 | Frost Stephen J | Weighted Scoring Methods and Use Thereof in Screening |
WO2007076439A2 (en) | 2005-12-22 | 2007-07-05 | Abbott Laboratories | Methods and marker combinations for screening for predisposition to lung cancer |
US9347945B2 (en) * | 2005-12-22 | 2016-05-24 | Abbott Molecular Inc. | Methods and marker combinations for screening for predisposition to lung cancer |
US7960110B2 (en) | 2006-11-15 | 2011-06-14 | The Regents Of The University Of California | Detection of chromosomal region copy number changes to diagnose melanoma |
US8679759B2 (en) * | 2007-08-01 | 2014-03-25 | The Johns Hopkins University | Esophageal cancer markers |
EP3308719B1 (en) | 2011-05-26 | 2022-03-30 | ADN International, LLC | Expandable device for tissue collection from an aerodigestive body lumen |
EP2758544B1 (en) * | 2011-09-23 | 2017-10-18 | Academisch Medisch Centrum | Materials and methods for prognosis of progression of barrett's esophagus |
US10255410B2 (en) * | 2011-12-01 | 2019-04-09 | Interpace Diagnostics Corporation | Methods for treating Barrett's metaplasia and esophageal adenocarcinoma |
US10131942B2 (en) | 2011-12-01 | 2018-11-20 | Interpace Diagnostics Corporation | Methods for treating barrett's metaplasia and esophageal adenocarcinoma |
US20150159220A1 (en) * | 2012-05-11 | 2015-06-11 | Fred Hutchinson Cancer Research Center | Methods for predicting and detecting cancer risk |
EP3066214B1 (en) * | 2013-11-07 | 2019-10-02 | Cellay, Inc. | Methods and kits for detecting a prostate carcinoma and predicting disease outcomes for prostate cancers |
DK3109324T5 (en) * | 2015-06-23 | 2019-02-11 | Zytovision Gmbh | PROCEDURE FOR THE DETECTION OF CHROMOSOMA DIFFERENCES |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US617468A (en) | 1899-01-10 | miller | ||
US5756696A (en) | 1986-01-16 | 1998-05-26 | Regents Of The University Of California | Compositions for chromosome-specific staining |
US5491224A (en) | 1990-09-20 | 1996-02-13 | Bittner; Michael L. | Direct label transaminated DNA probe compositions for chromosome identification and methods for their manufacture |
US6174681B1 (en) | 1999-03-05 | 2001-01-16 | Mayo Foundation For Medical Education And Research | Method and probe set for detecting cancer |
ES2372007T3 (es) * | 2001-02-20 | 2012-01-12 | Vysis, Inc. | Métodos y sondas para la detección del cáncer. |
-
2006
- 2006-02-17 EP EP17175085.4A patent/EP3246417B1/en active Active
- 2006-02-17 EP EP14176615.4A patent/EP2789697B1/en active Active
- 2006-02-17 ES ES06735413.4T patent/ES2528382T3/es active Active
- 2006-02-17 WO PCT/US2006/005739 patent/WO2006089163A2/en active Application Filing
- 2006-02-17 EP EP12178901.0A patent/EP2540842B8/en not_active Not-in-force
- 2006-02-17 CA CA2598006A patent/CA2598006C/en not_active Expired - Fee Related
- 2006-02-17 US US11/356,786 patent/US8034577B2/en not_active Expired - Fee Related
- 2006-02-17 JP JP2007556340A patent/JP2008537097A/ja active Pending
- 2006-02-17 EP EP06735413.4A patent/EP1853729B1/en not_active Not-in-force
- 2006-02-17 ES ES14176615.4T patent/ES2644641T3/es active Active
- 2006-02-17 ES ES12178901.0T patent/ES2575697T3/es active Active
-
2011
- 2011-10-07 US US13/268,168 patent/US20120141991A1/en not_active Abandoned
-
2015
- 2015-04-28 JP JP2015091283A patent/JP6371252B2/ja not_active Expired - Fee Related
-
2017
- 2017-06-29 JP JP2017127250A patent/JP6662813B2/ja not_active Expired - Fee Related
-
2019
- 2019-08-01 JP JP2019142115A patent/JP2019213542A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1853729B1 (en) | 2014-12-03 |
JP6662813B2 (ja) | 2020-03-11 |
JP2017205119A (ja) | 2017-11-24 |
EP2789697A3 (en) | 2015-01-21 |
EP2540842B8 (en) | 2016-06-01 |
EP3246417A1 (en) | 2017-11-22 |
EP2540842A2 (en) | 2013-01-02 |
EP2540842B1 (en) | 2016-04-06 |
EP1853729A4 (en) | 2010-05-05 |
US20060211019A1 (en) | 2006-09-21 |
JP2019213542A (ja) | 2019-12-19 |
EP2540842A3 (en) | 2013-04-03 |
ES2528382T3 (es) | 2015-02-09 |
JP2008537097A (ja) | 2008-09-11 |
EP1853729A2 (en) | 2007-11-14 |
CA2598006A1 (en) | 2006-08-24 |
US8034577B2 (en) | 2011-10-11 |
ES2644641T3 (es) | 2017-11-29 |
JP2015165807A (ja) | 2015-09-24 |
US20120141991A1 (en) | 2012-06-07 |
WO2006089163A3 (en) | 2009-06-04 |
JP6371252B2 (ja) | 2018-08-08 |
EP2789697A2 (en) | 2014-10-15 |
CA2598006C (en) | 2018-12-11 |
EP2789697B1 (en) | 2017-07-19 |
EP3246417B1 (en) | 2019-09-11 |
WO2006089163A2 (en) | 2006-08-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2575697T3 (es) | Métodos y sondas para detectar cáncer de esófago | |
Hong et al. | MicroRNA expression profiling of diagnostic needle aspirates from surgical pancreatic cancer specimens | |
Silakit et al. | Circulating mi R‐192 in liver fluke‐associated cholangiocarcinoma patients: a prospective prognostic indicator | |
CN107012213A (zh) | 结直肠癌的生物标记物 | |
ES2638640T3 (es) | Ensayo de HPV RNAscope® para determinar el estado del HPV en los cánceres de cabeza y cuello y en lesiones cervicales | |
Wang et al. | Downregulation of microRNA-124 is an independent prognostic factor in patients with colorectal cancer | |
CY1118000T1 (el) | Διαδικασια υψηλης παροχης για αναλυση μεθυλιωσης dna | |
ES2659798T3 (es) | Detección de la restricción de cadena ligera de inmunoglobulina por hibridación in situ de ARN | |
WO2006115570A3 (en) | Small nucleic acid detection probes and uses thereof | |
CN106574303A (zh) | 用于结肠直肠癌的甲基化的标志物 | |
DE602008006254D1 (de) | Doppel-oligonukleotid-nukleinsäurenachweisverfahren | |
WO2016168174A1 (en) | Predicting the occurrence of metastatic cancer using epigenomic biomarkers and non-invasive methodologies | |
Vinarskaja et al. | ID4 is frequently downregulated and partially hypermethylated in prostate cancer | |
ES2721539T3 (es) | Materiales y métodos para pronóstico de evolución de esófago de Barrett | |
DK1631686T3 (da) | Påvisning af dysplasi i høj grad i cervicale celler | |
DE602005023002D1 (de) | Hybridisierungsverfahren | |
H Corvalan et al. | Recent patents of DNA methylation biomarkers in gastrointestinal oncology | |
CY1114785T1 (el) | Ανιχνευση και καταμετρηση μικροοργανισμων | |
JPWO2008149855A1 (ja) | メチル化核酸又は非メチル化核酸を増幅する方法 | |
WO2006131677A3 (fr) | Procede pour le diagnostic/pronostic du cancer du sein | |
DE602004030910D1 (de) | Verfahren und nukleinsäuren zur analyse von störungen der proliferation von kolonzellen | |
JPWO2019178496A5 (es) | ||
ES2720864T3 (es) | Materiales y métodos para el diagnóstico y pronóstico de cáncer pancreatobiliar | |
AR068324A1 (es) | Marcadores de cancer oral y su deteccion | |
HRP20120761T1 (hr) | Postupak detekcije i dijagnosticiranja raka koji ukljuäśuje poäśetnice i sonde za specifiäśnu detekciju markera mage-a3 |