DE602004030910D1 - Verfahren und nukleinsäuren zur analyse von störungen der proliferation von kolonzellen - Google Patents
Verfahren und nukleinsäuren zur analyse von störungen der proliferation von kolonzellenInfo
- Publication number
- DE602004030910D1 DE602004030910D1 DE602004030910T DE602004030910T DE602004030910D1 DE 602004030910 D1 DE602004030910 D1 DE 602004030910D1 DE 602004030910 T DE602004030910 T DE 602004030910T DE 602004030910 T DE602004030910 T DE 602004030910T DE 602004030910 D1 DE602004030910 D1 DE 602004030910D1
- Authority
- DE
- Germany
- Prior art keywords
- nucleic acids
- colonocells
- proliferation
- analyzing problems
- disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 230000035755 proliferation Effects 0.000 title 1
- 210000001072 colon Anatomy 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 230000011987 methylation Effects 0.000 abstract 1
- 238000007069 methylation reaction Methods 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60313803A | 2003-06-23 | 2003-06-23 | |
PCT/US2004/020279 WO2005001140A2 (en) | 2003-06-23 | 2004-06-23 | Methods and nucleic acids for the analysis of colon cell proliferative disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004030910D1 true DE602004030910D1 (de) | 2011-02-17 |
Family
ID=33552178
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004030910T Active DE602004030910D1 (de) | 2003-06-23 | 2004-06-23 | Verfahren und nukleinsäuren zur analyse von störungen der proliferation von kolonzellen |
Country Status (5)
Country | Link |
---|---|
US (1) | US8163488B2 (de) |
EP (1) | EP1636381B1 (de) |
AT (1) | ATE494390T1 (de) |
DE (1) | DE602004030910D1 (de) |
WO (1) | WO2005001140A2 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7943308B2 (en) | 2004-06-23 | 2011-05-17 | Epigenomics Ag | Methods and nucleic acids for the detection of metastasis of colon cell proliferative disorders |
US20130071836A9 (en) * | 2004-11-08 | 2013-03-21 | Sungwhan An | Colon cancer biomarker discovery |
US20070059753A1 (en) * | 2005-09-15 | 2007-03-15 | Tatiana Vener | Detecting gene methylation |
AU2007237444B2 (en) * | 2006-04-17 | 2013-05-23 | Epigenomics Ag | Methods and nucleic acids for the detection of colorectal cell proliferative disorders |
GB0700374D0 (en) * | 2007-01-09 | 2007-02-14 | Oncomethylome Sciences S A | NDRG family methylation markers |
ES2346503B1 (es) | 2008-11-03 | 2011-08-03 | Fina Biotech, S.L.U. | Metodo de diagnostico de cancer colorectal. |
US8053189B2 (en) | 2008-11-03 | 2011-11-08 | Fina Biotech, S.L.U. | Method for the diagnosis of colorectal cancer |
CA2852851A1 (en) * | 2011-10-17 | 2013-04-25 | King Abdullah University Of Science And Technology | Composite biomarker for non-invasive screening, diagnosis and prognosis of colorectal cancer |
US11473131B2 (en) | 2014-08-22 | 2022-10-18 | The Trustees Of The University Of Pennsylvania | Methods for detecting genomic DNA methylation |
WO2018031760A1 (en) | 2016-08-10 | 2018-02-15 | Grail, Inc. | Methods of preparing dual-indexed dna libraries for bisulfite conversion sequencing |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5585481A (en) * | 1987-09-21 | 1996-12-17 | Gen-Probe Incorporated | Linking reagents for nucleotide probes |
US5457183A (en) * | 1989-03-06 | 1995-10-10 | Board Of Regents, The University Of Texas System | Hydroxylated texaphyrins |
US5245022A (en) * | 1990-08-03 | 1993-09-14 | Sterling Drug, Inc. | Exonuclease resistant terminally substituted oligonucleotides |
US5565552A (en) * | 1992-01-21 | 1996-10-15 | Pharmacyclics, Inc. | Method of expanded porphyrin-oligonucleotide conjugate synthesis |
US5574142A (en) * | 1992-12-15 | 1996-11-12 | Microprobe Corporation | Peptide linkers for improved oligonucleotide delivery |
SE501439C2 (sv) | 1993-06-22 | 1995-02-13 | Pharmacia Lkb Biotech | Sätt och anordning för analys av polynukleotidsekvenser |
DE69417918T2 (de) | 1993-11-30 | 2000-01-05 | Univ Montreal Mcgill | Dna methyltransferase inhibierung |
US5597696A (en) * | 1994-07-18 | 1997-01-28 | Becton Dickinson And Company | Covalent cyanine dye oligonucleotide conjugates |
US6017704A (en) | 1996-06-03 | 2000-01-25 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
US5786146A (en) * | 1996-06-03 | 1998-07-28 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
AU7829398A (en) * | 1997-06-09 | 1998-12-30 | University Of Southern California | A cancer diagnostic method based upon dna methylation differences |
DE19754482A1 (de) | 1997-11-27 | 1999-07-01 | Epigenomics Gmbh | Verfahren zur Herstellung komplexer DNA-Methylierungs-Fingerabdrücke |
US7700324B1 (en) | 1998-11-03 | 2010-04-20 | The Johns Hopkins University School Of Medicine | Methylated CpG island amplification (MCA) |
US5958773A (en) * | 1998-12-17 | 1999-09-28 | Isis Pharmaceuticals Inc. | Antisense modulation of AKT-1 expression |
US6331393B1 (en) * | 1999-05-14 | 2001-12-18 | University Of Southern California | Process for high-throughput DNA methylation analysis |
JP2004505612A (ja) | 2000-03-31 | 2004-02-26 | ユニバーシティ・オブ・サザン・カリフォルニア | 食道腺ガンに関する後成的配列 |
-
2004
- 2004-06-23 AT AT04756023T patent/ATE494390T1/de not_active IP Right Cessation
- 2004-06-23 DE DE602004030910T patent/DE602004030910D1/de active Active
- 2004-06-23 WO PCT/US2004/020279 patent/WO2005001140A2/en active Application Filing
- 2004-06-23 US US10/562,089 patent/US8163488B2/en not_active Expired - Fee Related
- 2004-06-23 EP EP04756023A patent/EP1636381B1/de not_active Not-in-force
Also Published As
Publication number | Publication date |
---|---|
US20090047666A1 (en) | 2009-02-19 |
ATE494390T1 (de) | 2011-01-15 |
EP1636381B1 (de) | 2011-01-05 |
WO2005001140A3 (en) | 2005-03-24 |
WO2005001140A2 (en) | 2005-01-06 |
US8163488B2 (en) | 2012-04-24 |
EP1636381A2 (de) | 2006-03-22 |
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