DE60329224D1 - Verfahren zur Bestimmung von zirkulierender DNS in Plasma und zum Nachweis von Krebs - Google Patents
Verfahren zur Bestimmung von zirkulierender DNS in Plasma und zum Nachweis von KrebsInfo
- Publication number
- DE60329224D1 DE60329224D1 DE60329224T DE60329224T DE60329224D1 DE 60329224 D1 DE60329224 D1 DE 60329224D1 DE 60329224 T DE60329224 T DE 60329224T DE 60329224 T DE60329224 T DE 60329224T DE 60329224 D1 DE60329224 D1 DE 60329224D1
- Authority
- DE
- Germany
- Prior art keywords
- cancer
- plasma
- determination
- detection
- circulating dna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 5
- 201000011510 cancer Diseases 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000013399 early diagnosis Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT002743A ITMI20022743A1 (it) | 2002-12-23 | 2002-12-23 | Metodo per la determinazione del rischio di comparsa, della presenza o del decorso di malattie tumorali. |
| PCT/EP2003/014719 WO2004057024A1 (en) | 2002-12-23 | 2003-12-22 | Method for the detection of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60329224D1 true DE60329224D1 (de) | 2009-10-22 |
Family
ID=32676859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60329224T Expired - Lifetime DE60329224D1 (de) | 2002-12-23 | 2003-12-22 | Verfahren zur Bestimmung von zirkulierender DNS in Plasma und zum Nachweis von Krebs |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7888008B2 (de) |
| EP (1) | EP1576187B1 (de) |
| AT (1) | ATE442456T1 (de) |
| AU (1) | AU2003294932A1 (de) |
| DE (1) | DE60329224D1 (de) |
| DK (1) | DK1576187T3 (de) |
| ES (1) | ES2332716T3 (de) |
| IT (1) | ITMI20022743A1 (de) |
| WO (1) | WO2004057024A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602005009324D1 (de) * | 2005-04-06 | 2008-10-09 | Maurice Stroun | Methode zur Krebsdiagnose mittels Nachweis von DNA und RNA im Kreislauf |
| CN104593505A (zh) * | 2015-01-23 | 2015-05-06 | 上海迪安医学检验所有限公司 | 一种检测全血或血清样品中端粒酶的活性程度的试剂盒 |
| JP7239973B2 (ja) * | 2017-12-19 | 2023-03-15 | 国立大学法人山口大学 | 前癌病変又は癌の有無の予測を補助する方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2248981C (en) * | 1996-03-15 | 2009-11-24 | The Penn State Research Foundation | Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays |
| US6475789B1 (en) * | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
| CA2321259A1 (en) | 1998-02-16 | 1999-08-19 | University Of Maryland, Baltimore | Telomerase assay of body fluids for cancer screening and assessment of disease stage and prognosis |
| US7160996B1 (en) * | 1999-06-09 | 2007-01-09 | Bioresearch Technologies, Inc. | Fluorescence energy transfer probes with stabilized conformations |
| US6664046B1 (en) * | 1999-12-16 | 2003-12-16 | Roche Molecular Systems, Inc. | Quantitation of hTERT mRNA expression |
| EP1158055A1 (de) * | 2000-05-26 | 2001-11-28 | Xu Qi University of Teaxs Laboratoire de Leucémie Chen | Verfahren zur Diagnose von Krebs |
-
2002
- 2002-12-23 IT IT002743A patent/ITMI20022743A1/it unknown
-
2003
- 2003-12-22 AT AT03785912T patent/ATE442456T1/de not_active IP Right Cessation
- 2003-12-22 DK DK03785912T patent/DK1576187T3/da active
- 2003-12-22 WO PCT/EP2003/014719 patent/WO2004057024A1/en not_active Application Discontinuation
- 2003-12-22 DE DE60329224T patent/DE60329224D1/de not_active Expired - Lifetime
- 2003-12-22 AU AU2003294932A patent/AU2003294932A1/en not_active Abandoned
- 2003-12-22 ES ES03785912T patent/ES2332716T3/es not_active Expired - Lifetime
- 2003-12-22 US US10/538,495 patent/US7888008B2/en not_active Expired - Fee Related
- 2003-12-22 EP EP03785912A patent/EP1576187B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20070148644A1 (en) | 2007-06-28 |
| ITMI20022743A1 (it) | 2004-06-24 |
| ES2332716T3 (es) | 2010-02-11 |
| ATE442456T1 (de) | 2009-09-15 |
| US7888008B2 (en) | 2011-02-15 |
| EP1576187A1 (de) | 2005-09-21 |
| DK1576187T3 (da) | 2010-01-11 |
| AU2003294932A1 (en) | 2004-07-14 |
| WO2004057024A1 (en) | 2004-07-08 |
| EP1576187B1 (de) | 2009-09-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60207979D1 (de) | Verfahren und Vorrichtung zur Bestimmung der Gewebespezifität von freier DNA in Körperflüssigkeiten | |
| BRPI0607508B8 (pt) | método para detecção e/ou classificação de distúrbios proliferativos celulares colorretais ou hepatocelulares, e uso do mesmo | |
| ATE419390T1 (de) | Verfahren zur diagnose von bauchspeicheldrüsenkrebs | |
| ATE508202T1 (de) | Verfahren zur diagnose von brustkrebs | |
| DE60239470D1 (de) | Verfahren zur bewertung pathologischer krankheitszustände unter verwendung extrazellulärer rna | |
| WO2004020968A3 (en) | Mutations in nod2 are associated with fibrostenosing disease in patients with crohn’s disease | |
| JP2009538607A5 (de) | ||
| WO2005040396A3 (en) | qRT-PCR ASSAY SYSTEM FOR GENE EXPRESSION PROFILING | |
| ATE406575T1 (de) | Verfahren zur erkennung von medikamentenempfindlichkeit in patienten mit entzündungskrankheiten | |
| WO2005085860A3 (en) | New proliferation markers in clinical practice and their use for cancer prognosis or diagnosis | |
| ATE454468T1 (de) | Nachweis der instabilität von mikrosatelliten und verwendung davon bei der tumordiagnose | |
| ATE426043T1 (de) | Verfahren zur identifizierung des brustkrebsrisikos | |
| ATE370414T1 (de) | Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs | |
| WO2006002240A3 (en) | Computer systems and methods for constructing biological classifiers and uses thereof | |
| DE60325382D1 (de) | Verfahren zur diagnose von gebärmutterhalskrebs | |
| WO2005001141A8 (en) | Methods and nucleic acids for analyses of colorectal cell proliferative disorders | |
| ATE494390T1 (de) | Verfahren und nukleinsäuren zur analyse von störungen der proliferation von kolonzellen | |
| DE602005023329D1 (de) | VERFAHREN ZUR DIAGNOSE NICHT-KLEINZELLIGER LUNGENKARZINOME ÜBER DIE tRNA-DIHYDROURIDIN-SYNTHASEAKTIVITÄT VON URLC8 | |
| WO2004109286A3 (en) | Methods for detecting and treating cancer using podocalyxin and/or endoglycan | |
| DE60329224D1 (de) | Verfahren zur Bestimmung von zirkulierender DNS in Plasma und zum Nachweis von Krebs | |
| WO2006022619A3 (en) | Methods for identifying risk of type ii diabetes and treatments thereof | |
| RU2012133434A (ru) | Способы и наборы для детекции факторов риска развития остеонекроза челюсти и способы его лечения | |
| WO2008018789A3 (en) | Methods and means for diagnosing and treatment of osteoarthritis | |
| DE60309879D1 (de) | Verfahren zur Diagnose von Krebs | |
| ATE515576T1 (de) | Protein c polymorphismen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |