ATE454468T1 - Nachweis der instabilität von mikrosatelliten und verwendung davon bei der tumordiagnose - Google Patents

Nachweis der instabilität von mikrosatelliten und verwendung davon bei der tumordiagnose

Info

Publication number
ATE454468T1
ATE454468T1 AT02731467T AT02731467T ATE454468T1 AT E454468 T1 ATE454468 T1 AT E454468T1 AT 02731467 T AT02731467 T AT 02731467T AT 02731467 T AT02731467 T AT 02731467T AT E454468 T1 ATE454468 T1 AT E454468T1
Authority
AT
Austria
Prior art keywords
instability
microsatellites
detection
kits
methods
Prior art date
Application number
AT02731467T
Other languages
English (en)
Inventor
Jeffery Bacher
Laura Flanagan
Nadine Nassif
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promega Corp filed Critical Promega Corp
Application granted granted Critical
Publication of ATE454468T1 publication Critical patent/ATE454468T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Saccharide Compounds (AREA)
AT02731467T 2001-04-24 2002-04-24 Nachweis der instabilität von mikrosatelliten und verwendung davon bei der tumordiagnose ATE454468T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/841,366 US20020058265A1 (en) 2000-09-15 2001-04-24 Detection of microsatellite instability and its use in diagnosis of tumors
PCT/US2002/012779 WO2002086448A2 (en) 2001-04-24 2002-04-24 Detection of microsatellite instability and its use in diagnosis of tumors

Publications (1)

Publication Number Publication Date
ATE454468T1 true ATE454468T1 (de) 2010-01-15

Family

ID=25284685

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02731467T ATE454468T1 (de) 2001-04-24 2002-04-24 Nachweis der instabilität von mikrosatelliten und verwendung davon bei der tumordiagnose

Country Status (8)

Country Link
US (3) US20020058265A1 (de)
EP (1) EP1390538B1 (de)
JP (1) JP2004533241A (de)
AT (1) ATE454468T1 (de)
AU (1) AU2002303444A1 (de)
DE (1) DE60235005D1 (de)
ES (1) ES2338765T3 (de)
WO (1) WO2002086448A2 (de)

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US20020058265A1 (en) 2000-09-15 2002-05-16 Promega Corporation Detection of microsatellite instability and its use in diagnosis of tumors
US20060115844A1 (en) 2004-10-22 2006-06-01 Finkelstein Sydney D Enhanced amplifiability of minute fixative-treated tissue samples, minute stained cytology samples, and other minute sources of DNA
WO2006047536A2 (en) * 2004-10-22 2006-05-04 Promega Corporation Methods and kits for detecting mutations
JP4713138B2 (ja) * 2004-12-06 2011-06-29 株式会社日立ソリューションズ 遺伝子情報の表示方法及び表示装置及びプログラム
EP2218794A1 (de) * 2009-02-13 2010-08-18 Alphagenics International SA Instabilitätserkennung in Regionen mit genomischem DNA mit einfacher Tandemwiederholung
US20100317534A1 (en) * 2009-06-12 2010-12-16 Board Of Regents, The University Of Texas System Global germ line and tumor microsatellite patterns are cancer biomarkers
FR2960553B1 (fr) * 2010-06-01 2014-09-05 Ct Europ D Expertise Et De Rech Sur Les Agents Microbiens Ceeram Procede de genotypage de staphylococcus aureus
FR2960552B1 (fr) * 2010-06-01 2015-08-07 Ct Europ D Expertise Et De Rech Sur Les Agents Microbiens Ceeram Procede de genotypage de legionella pneumophila
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JP5895290B2 (ja) * 2011-08-15 2016-03-30 有限会社カホテクノ 非ヒト被験体から取得した乳腺腫瘍サンプルが悪性腫瘍である可能性を診断する方法、システムおよびキット
US9341628B2 (en) 2012-11-30 2016-05-17 Interpace Diagnostics Corporation Methods for measuring carcinoembryonic antigen
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CN106701978A (zh) * 2017-01-24 2017-05-24 厦门艾德生物医药科技股份有限公司 一种人类微卫星不稳定性msi检测扩增引物组合物及试剂盒
AU2018240195A1 (en) * 2017-03-20 2019-10-17 Caris Mpi, Inc. Genomic stability profiling
CN111373050A (zh) 2017-06-20 2020-07-03 生物辐射实验室股份有限公司 用于遗传不稳定性的数字扩增试验
US11773449B2 (en) 2017-09-01 2023-10-03 The Hospital For Sick Children Profiling and treatment of hypermutant cancer
CA3076925A1 (en) * 2017-10-19 2019-04-25 Nantomics, Llc Msi from liquid biopsies
CN108866188B (zh) * 2018-07-12 2022-03-01 吉林大学 一种消化道恶性肿瘤易感性预测试剂盒及系统
CN108841960B (zh) * 2018-07-12 2022-02-01 吉林大学 一种结肠腺癌易感性预测试剂盒及系统
CN108676891B (zh) * 2018-07-12 2022-02-01 吉林大学 一种直肠腺癌易感性预测试剂盒及系统
EP3739064A1 (de) 2019-05-15 2020-11-18 Biotype GmbH Vergleichende analyse von mikrosatelliten mittels kapillarelektrophorese (ce) -dna-profile
US20210139950A1 (en) * 2019-11-08 2021-05-13 Life Technologies Corporation Microsatellite instability measurement
US20210147946A1 (en) * 2019-11-08 2021-05-20 Life Technologies Corporation Systems and assays for assessing microsatellite instability
CN110951851A (zh) * 2019-12-24 2020-04-03 北京优迅医学检验实验室有限公司 用于微卫星不稳定检测的引物组和方法
CN111763739B (zh) * 2020-08-11 2022-08-23 郑州科蒂亚生物技术有限公司 一种肿瘤微卫星不稳定检测引物及其应用和试剂盒

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Also Published As

Publication number Publication date
US7202031B2 (en) 2007-04-10
US20070117136A1 (en) 2007-05-24
EP1390538A2 (de) 2004-02-25
EP1390538A4 (de) 2005-08-03
AU2002303444A1 (en) 2002-11-05
JP2004533241A (ja) 2004-11-04
US7749706B2 (en) 2010-07-06
WO2002086448A2 (en) 2002-10-31
ES2338765T3 (es) 2010-05-12
WO2002086448B1 (en) 2003-12-11
DE60235005D1 (de) 2010-02-25
US20020058265A1 (en) 2002-05-16
WO2002086448A3 (en) 2003-11-13
EP1390538B1 (de) 2010-01-06
US20030180758A1 (en) 2003-09-25

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