ATE515575T1 - Verfahren und sonden für den nachweis von krebs - Google Patents

Verfahren und sonden für den nachweis von krebs

Info

Publication number
ATE515575T1
ATE515575T1 AT02721122T AT02721122T ATE515575T1 AT E515575 T1 ATE515575 T1 AT E515575T1 AT 02721122 T AT02721122 T AT 02721122T AT 02721122 T AT02721122 T AT 02721122T AT E515575 T1 ATE515575 T1 AT E515575T1
Authority
AT
Austria
Prior art keywords
methods
cancer
probe
detecting cancer
probes
Prior art date
Application number
AT02721122T
Other languages
English (en)
Inventor
Larry Morrison
Irina Sokolova
Steven Seelig
Kevin Halling
Original Assignee
Vysis Inc
Mayo Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vysis Inc, Mayo Foundation filed Critical Vysis Inc
Application granted granted Critical
Publication of ATE515575T1 publication Critical patent/ATE515575T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
AT02721122T 2001-02-20 2002-02-20 Verfahren und sonden für den nachweis von krebs ATE515575T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27027101P 2001-02-20 2001-02-20
PCT/US2002/005379 WO2002066685A1 (en) 2001-02-20 2002-02-20 Methods and probes for the detection of cancer

Publications (1)

Publication Number Publication Date
ATE515575T1 true ATE515575T1 (de) 2011-07-15

Family

ID=23030623

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02721122T ATE515575T1 (de) 2001-02-20 2002-02-20 Verfahren und sonden für den nachweis von krebs

Country Status (7)

Country Link
US (4) US20030087248A1 (de)
EP (1) EP1362124B1 (de)
JP (1) JP4251437B2 (de)
AT (1) ATE515575T1 (de)
CA (2) CA2750033A1 (de)
ES (1) ES2372007T3 (de)
WO (1) WO2002066685A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0878552A1 (de) * 1997-05-13 1998-11-18 Erasmus Universiteit Rotterdam Molekularer Nachweis von chromosomalen Veränderungen
AU3516899A (en) * 1998-05-04 1999-11-23 Dako A/S Method and probes for the detection of chromosome aberrations
US6797471B2 (en) * 2000-08-04 2004-09-28 Board Of Regents, The University Of Texas System Detection and diagnosis of smoking related cancers
ES2372007T3 (es) * 2001-02-20 2012-01-12 Vysis, Inc. Métodos y sondas para la detección del cáncer.
ATE361471T1 (de) 2001-12-05 2007-05-15 Sense Proteomic Ltd Protein arrays für allelvarianten und deren verwendung
WO2004042032A2 (en) * 2002-11-01 2004-05-21 The Ohio State University Research Foundation Cytogenetic abnormalities that are predictive of response to therapy for chronic lymphocytic leukemia
EP1631686B1 (de) 2003-06-09 2012-05-09 Vysis, Inc. Nachweis hochgradiger dysplasie in zervixzellen
US20040248107A1 (en) * 2003-06-09 2004-12-09 Sokolova Irina A. Detection of high grade dysplasia in cervical cells
CA2567293C (en) * 2004-05-27 2017-05-16 The Regents Of The University Of Colorado Methods for prediction of clinical outcome to epidermal growth factor receptor inhibitors by cancer patients
EP2540842B8 (de) 2005-02-18 2016-06-01 Abbott Molecular Inc. Verfahren und Sonden zur Erkennung von Speiseröhrenkrebs
CA2599445C (en) * 2005-03-09 2022-05-03 Abbott Laboratories Diagnostics method for identifying candidate patients for the treatment with trastuzumab
ES2618858T3 (es) 2005-09-02 2017-06-22 The Regents Of The University Of California Métodos y combinaciones de pruebas para detectar melanoma
US20070178503A1 (en) * 2005-12-19 2007-08-02 Feng Jiang In-situ genomic DNA chip for detection of cancer
EP1989329A2 (de) * 2006-01-25 2008-11-12 Board of Regents, The University of Texas System Erkennung und diagnose von durch rauchen bedingten krebserkrankungen
US20080026366A1 (en) * 2006-06-07 2008-01-31 Newcomer Supply, Inc. Biological fixative and method of using the biological fixative
US20090208965A1 (en) * 2006-10-25 2009-08-20 Ikonisys, Inc. Automated method for detecting cancers and high grade hyperplasias
KR20090071667A (ko) * 2006-10-25 2009-07-01 아이코니시스 인코포레이티드 암 및 고등급 과형성증의 자동화된 검출
US20080113350A1 (en) * 2006-11-09 2008-05-15 Terstappen Leon W M M Blood test to monitor the genetic changes of progressive cancer using immunomagnetic enrichment and fluorescence in situ hybridization (FISH)
US7960110B2 (en) 2006-11-15 2011-06-14 The Regents Of The University Of California Detection of chromosomal region copy number changes to diagnose melanoma
US20100291569A1 (en) * 2006-11-30 2010-11-18 Abbott Laboratories Assay for prediction of response to met antagonists
EP2185573A4 (de) * 2007-07-26 2011-12-07 Cellay Inc Hochsichtbare chromosomenspezifische sonden und entsprechende verfahren
WO2009047756A2 (en) * 2007-10-11 2009-04-16 Bioview Ltd. Methods and kits for diagnosing lung cancer
US20090258365A1 (en) 2008-03-25 2009-10-15 Terstappen Leon W M M METHOD FOR DETECTING IGF1R/Chr 15 in CIRCULATING TUMOR CELLS USING FISH
CA2731781A1 (en) * 2008-07-21 2010-01-28 Neodiagnostix, Inc. Methods for the cytological analysis of cervical cells
US8785131B2 (en) * 2008-11-11 2014-07-22 Abbott Laboratories Prognostic test for early stage non small cell lung cancer (NSCLC)
WO2010083852A1 (en) * 2009-01-26 2010-07-29 Tethis S.R.L. Functionalized microfluidic device for immunofluorescence
JP2013507988A (ja) 2009-10-26 2013-03-07 アボット・ラボラトリーズ 非小細胞肺癌の予後を決定するための診断方法
EP2494076B1 (de) 2009-10-26 2017-11-22 Abbott Molecular Inc. Erkennung von chromosomenanomalien in verbindung mit der prognose von nicht kleinzelligem lungenkrebs
CN106399506A (zh) 2009-10-26 2017-02-15 雅培分子公司 用于测定非小细胞肺癌预后的诊断方法
US9469877B2 (en) * 2011-12-30 2016-10-18 Abbott Molecular Inc. Materials and methods for diagnosis, prognosis, monitoring of recurrence, and assessment of therapeutic/prophylactic treatment of pancreatobiliary cancer
EP2798082B1 (de) * 2011-12-30 2017-04-12 Abbott Molecular Inc. Materialien und verfahren zur diagnose, prognose und beurteilung einer therapeutischen/prophylaktischen behandlung von prostatakrebs
WO2015125027A2 (en) * 2014-02-12 2015-08-27 Leica Biosystems Newcastle Ltd. Kit and method for detecting bladder cancer
US20160083791A1 (en) * 2014-09-18 2016-03-24 Pathadvantage Associated System and method for detecting abnormalities in cervical cells
JP2019195304A (ja) 2018-05-10 2019-11-14 学校法人順天堂 画像解析方法、装置、コンピュータプログラム、及び深層学習アルゴリズムの生成方法
JP7381003B2 (ja) * 2019-04-26 2023-11-15 学校法人順天堂 疾患解析を支援する方法、装置、及びコンピュータプログラム、並びにコンピュータアルゴリズムを訓練する方法、装置、及びプログラム
WO2023097244A1 (en) * 2021-11-24 2023-06-01 Yale University Methods of determining chromatin alterations

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981725A (en) * 1989-09-08 1999-11-09 The Johns Hopkins Univiersity Structural alterations of the EGF receptor gene in human tumors
US5491224A (en) * 1990-09-20 1996-02-13 Bittner; Michael L. Direct label transaminated DNA probe compositions for chromosome identification and methods for their manufacture
US5658792A (en) * 1990-11-14 1997-08-19 The United States Of America As Represented By The Department Of Health And Human Services Antiproliferative protein
US5965362A (en) * 1992-03-04 1999-10-12 The Regents Of The University Of California Comparative genomic hybridization (CGH)
US5670314A (en) * 1994-02-22 1997-09-23 Regents Of The University Of California Genetic alterations that correlate with lung carcinomas
US5658730A (en) * 1994-12-23 1997-08-19 Ctrc Research Foundation Methods of human prostate cancer diagnosis
US5919624A (en) * 1997-01-10 1999-07-06 The United States Of America As Represented By The Department Of Health & Human Services Methods for detecting cervical cancer
US6174681B1 (en) * 1999-03-05 2001-01-16 Mayo Foundation For Medical Education And Research Method and probe set for detecting cancer
US6613510B2 (en) * 1999-04-28 2003-09-02 Mayo Foundation For Medical Education And Research Methods and probe sets for determining prostate cancer prognosis
US6180349B1 (en) * 1999-05-18 2001-01-30 The Regents Of The University Of California Quantitative PCR method to enumerate DNA copy number
ES2372007T3 (es) * 2001-02-20 2012-01-12 Vysis, Inc. Métodos y sondas para la detección del cáncer.

Also Published As

Publication number Publication date
EP1362124A1 (de) 2003-11-19
CA2750033A1 (en) 2002-08-29
EP1362124B1 (de) 2011-07-06
EP1362124A4 (de) 2005-04-20
US7998678B2 (en) 2011-08-16
US20120141987A1 (en) 2012-06-07
US20030087248A1 (en) 2003-05-08
JP2005505241A (ja) 2005-02-24
CA2438267A1 (en) 2002-08-29
US20060063194A1 (en) 2006-03-23
ES2372007T3 (es) 2012-01-12
JP4251437B2 (ja) 2009-04-08
WO2002066685A1 (en) 2002-08-29
US20090298087A1 (en) 2009-12-03
CA2438267C (en) 2012-05-15

Similar Documents

Publication Publication Date Title
ATE515575T1 (de) Verfahren und sonden für den nachweis von krebs
DE60029369D1 (de) Verfahren und Sondenset zur Erkennung von Krebs
ATE337011T1 (de) Modifizierte psma-liganden und deren verwendung
DE60030281D1 (de) Methoden zur verbesserung der sensitivität und spezifität von screeningverfahren für krebs und krebs-vorstufen
ATE350488T1 (de) Verfahren und testsysteme zur identifizierung von elite event gat-zm1 in biologischen proben
CY1105322T1 (el) Μεθοδοι και συνθεσεις για την ανιχνευση παθολογικων συμβαντων
ATE353977T1 (de) Methoden um dns von verschiedenen individuen nachzuweisen
DE602006003012D1 (de) Verfahren und Nukleinsäuren für die Analyse von zellulären Proliferationsstörungen
WO2002093130A3 (en) Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (fish)
HUP0303888A2 (hu) FKBP-nukleinsavak és -polipeptidek prosztatarák diagnosztizálására és gyógykezelésére alkalmas expressziós analízise
ATE426041T1 (de) Zirkulare sonden amplifizierung (cpa) von zirkularisierten nucleinsaure-molekulen
ATE430936T1 (de) Verwendung von cyfra 21-1 und osteopontin als marker für kolorektalkarzinome
ATE307902T1 (de) Methoden und testsätze zur probennahme und aufbewahrung von biologischen proben
DK1631686T3 (da) Påvisning af dysplasi i høj grad i cervicale celler
DE60315715D1 (de) Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs
ATE264922T1 (de) Verfahren zur erkennung von klonalen populationen von transformierten zellen in einer genomisch heterogenen zellulären probe
DE60142898D1 (de) Diagnostisches kit zur identifikation und feststellung von wirkstoffresistenz bei mykobakterium sowie herstellungsmethoden davon
DE60325382D1 (de) Verfahren zur diagnose von gebärmutterhalskrebs
ATE426168T1 (de) Verwendung von asc als marker fur kolorektalkarzinome
TR200402517T2 (tr) HBV ilaç direnci tespit metotları
ATE494390T1 (de) Verfahren und nukleinsäuren zur analyse von störungen der proliferation von kolonzellen
DK0983510T3 (da) Genkendelse af tumorspecifikke genprodukter i cancer
ATE435921T1 (de) Verfahren und system zur echtzeitanalyse von biosensordaten
HUP0303890A2 (hu) Differenciációs nukleinsavak és polipeptidek inhibitorának prosztatarák diagnosztizálására és gyógykezelésére alkalmas expressziós analízise
DE69912453D1 (de) Verfahren und materialien zur diagnose instabiler angina

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties