HRP20000323B1 - Spheroids, preparation method and pharmaceutical compositions - Google Patents

Spheroids, preparation method and pharmaceutical compositions

Info

Publication number
HRP20000323B1
HRP20000323B1 HR20000323A HRP20000323A HRP20000323B1 HR P20000323 B1 HRP20000323 B1 HR P20000323B1 HR 20000323 A HR20000323 A HR 20000323A HR P20000323 A HRP20000323 A HR P20000323A HR P20000323 B1 HRP20000323 B1 HR P20000323B1
Authority
HR
Croatia
Prior art keywords
spheroids
core
preparation
pharmaceutical compositions
less
Prior art date
Application number
HR20000323A
Other languages
English (en)
Croatian (hr)
Inventor
Debregeas Patrice
Leduc Gerard
Oury Pascal
Suplie Pascal
Original Assignee
Laboratoires Des Produits Ethiques Ethypharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Des Produits Ethiques Ethypharm filed Critical Laboratoires Des Produits Ethiques Ethypharm
Publication of HRP20000323A2 publication Critical patent/HRP20000323A2/hr
Publication of HRP20000323B1 publication Critical patent/HRP20000323B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HR20000323A 1997-11-21 2000-05-19 Spheroids, preparation method and pharmaceutical compositions HRP20000323B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9714631A FR2771291B1 (fr) 1997-11-21 1997-11-21 Spheroides, procede de preparation et compositions pharmaceutiques
PCT/IB1998/001911 WO1999026608A1 (fr) 1997-11-21 1998-11-19 Spheroides, procede de preparation et compositions pharmaceutiques

Publications (2)

Publication Number Publication Date
HRP20000323A2 HRP20000323A2 (en) 2001-06-30
HRP20000323B1 true HRP20000323B1 (en) 2006-07-31

Family

ID=9513635

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000323A HRP20000323B1 (en) 1997-11-21 2000-05-19 Spheroids, preparation method and pharmaceutical compositions

Country Status (29)

Country Link
US (1) US6077544A (da)
EP (1) EP1032374B1 (da)
JP (1) JP2001523706A (da)
KR (1) KR100502938B1 (da)
CN (1) CN1223341C (da)
AT (1) ATE246496T1 (da)
AU (1) AU744580B2 (da)
BG (1) BG65117B1 (da)
BR (1) BR9814672A (da)
CA (1) CA2310147C (da)
CZ (1) CZ299110B6 (da)
DE (1) DE69817010T2 (da)
DK (1) DK1032374T3 (da)
EA (1) EA003324B1 (da)
ES (1) ES2203989T3 (da)
FR (1) FR2771291B1 (da)
HR (1) HRP20000323B1 (da)
HU (1) HU230053B1 (da)
IL (2) IL136215A0 (da)
MX (1) MXPA00004959A (da)
NO (1) NO329728B1 (da)
NZ (1) NZ504662A (da)
PL (1) PL193878B1 (da)
PT (1) PT1032374E (da)
SK (1) SK284493B6 (da)
TR (1) TR200002130T2 (da)
WO (1) WO1999026608A1 (da)
YU (1) YU31000A (da)
ZA (1) ZA9810631B (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
US6794411B1 (en) 1999-04-06 2004-09-21 Laboratoire Des Produits Ethiques Ethypharm Drinkable ibuprofen pharmaceutical suspension
FR2794646B1 (fr) * 1999-06-09 2001-09-21 Ethypharm Lab Prod Ethiques Microgranules de sulfate de morphine, procede de preparation et composition les contenant
US7018821B2 (en) 2001-06-22 2006-03-28 Genencor International, Inc. Highly impact-resistant granules
AR034813A1 (es) † 2001-07-20 2004-03-17 Novartis Ag Composiciones farmaceuticas y uso de las mismas
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
FR2830447B1 (fr) * 2001-10-09 2004-04-16 Flamel Tech Sa Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
FR2837100B1 (fr) * 2002-03-18 2004-07-23 Flamel Tech Sa Comprimes a bases de microcapsules a liberation modifiee
CN100553625C (zh) 2002-04-09 2009-10-28 弗拉梅技术公司 活性成分微囊的口服混悬液
WO2003084517A2 (fr) * 2002-04-09 2003-10-16 Flamel Technologies Suspension orale de microcapsules d’amoxicilline
FR2838647B1 (fr) * 2002-04-23 2006-02-17 Particules enrobees a liberation prolongee, leur procede de preparation et comprimes les contenant
US20040013737A1 (en) * 2002-07-19 2004-01-22 Philippe Becourt Taste masked oral composition of telithromycin
FR2845289B1 (fr) * 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
US9107804B2 (en) * 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
NZ523946A (en) * 2003-01-31 2004-06-25 Carl Ernest Alexander Portable hygiene compositions comprising a semi-solid gel and active ingredients in bead form for use in personal oral, dental or skin care
ES2221804B1 (es) * 2003-06-18 2006-04-01 Lipofoods, S.L. Microcapsulas para la administracion de ingredientes activos.
US7569236B2 (en) * 2003-10-10 2009-08-04 Ethypharm Sustained-release microgranules containing gingko biloba extract and the process for manufacturing these
FR2861990B1 (fr) 2003-11-10 2006-02-10 Nouveaux Produits Pharma Comprimes faiblement doses a reseau de polymeres
US8236349B2 (en) * 2004-04-12 2012-08-07 Bend Research Inc. Taste-masked drugs in rupturing multiparticulates
US20070224269A1 (en) * 2004-06-10 2007-09-27 Rubino Orapin P Controlled Release Pharmaceutical Formulation
FR2883179B1 (fr) * 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US20100233257A1 (en) * 2006-06-09 2010-09-16 Ethypharm Low dose sublingual tablets of opioid analgesics and preparation process
US20070286900A1 (en) * 2006-06-09 2007-12-13 Catherine Herry Low dose tablets of opioid analgesics and preparation process
US10357462B2 (en) * 2006-11-30 2019-07-23 Ben Research, Inc. Multiparticulates of spray-coated drug and polymer on a meltable core
US11116728B2 (en) 2006-11-30 2021-09-14 Bend Research, Inc. Multiparticulates of spray-coated drug and polymer on a meltable core
EP2468263A1 (en) 2010-12-23 2012-06-27 Laboratorios Del. Dr. Esteve, S.A. Compressed solid dosage forms
CN114772256B (zh) 2018-05-11 2024-05-17 斯多里机械有限责任公司 快速更换式真空星轮组件和缩颈机
JP7312196B2 (ja) 2018-05-11 2023-07-20 ストール マシーナリ カンパニー，エルエルシー 回転マニホールド
BR112020022970A2 (pt) 2018-05-11 2021-02-02 Stolle Machinery Company, Llc recursos de mudança rápida de conjunto de alimentação
CN115673132A (zh) 2018-05-11 2023-02-03 斯多里机械有限责任公司 成型站和缩颈机
US11117180B2 (en) 2018-05-11 2021-09-14 Stolle Machinery Company, Llc Quick change tooling assembly
BR112020022859A2 (pt) 2018-05-11 2021-02-23 Stolle Machinery Company, Llc conjunto de inspeção completa de conjunto de alimentação
CN112118920B (zh) 2018-05-11 2023-04-14 斯多里机械有限责任公司 驱动组件
US11420242B2 (en) 2019-08-16 2022-08-23 Stolle Machinery Company, Llc Reformer assembly

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
CA1338596C (en) * 1988-09-27 1996-09-17 Hiroyoshi Koyama Granules having core and their production
EP0418596A3 (en) * 1989-09-21 1991-10-23 American Cyanamid Company Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
JP2572673B2 (ja) * 1990-07-25 1997-01-16 エスエス製薬株式会社 徐放性錠剤
FR2679451B1 (fr) * 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
GB9117361D0 (en) * 1991-08-12 1991-09-25 Euro Celtique Sa Oral dosage form
FR2692146B1 (fr) * 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
US5681582A (en) * 1993-06-14 1997-10-28 Janssen Pharmaceutica N.V. Extended release, film-coated tablet of astemizole and pseudoephedrine
SE9402422D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New beads for controlled release and a pharmaceutical preparation containing the same
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
FR2771292B1 (fr) * 1997-11-21 2000-02-18 Ethypharm Lab Prod Ethiques Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques

Also Published As

Publication number Publication date
ES2203989T3 (es) 2004-04-16
DE69817010D1 (de) 2003-09-11
US6077544A (en) 2000-06-20
AU1170499A (en) 1999-06-15
CA2310147C (fr) 2010-05-25
FR2771291B1 (fr) 2000-02-25
DE69817010T2 (de) 2004-05-27
KR100502938B1 (ko) 2005-07-25
CA2310147A1 (fr) 1999-06-03
HU230053B1 (hu) 2015-06-29
DK1032374T3 (da) 2003-11-24
PT1032374E (pt) 2003-12-31
MXPA00004959A (es) 2002-10-17
IL136215A (en) 2006-12-31
NO20002605D0 (no) 2000-05-19
PL193878B1 (pl) 2007-03-30
BG65117B1 (bg) 2007-03-30
ZA9810631B (en) 1999-05-24
TR200002130T2 (tr) 2000-12-21
HUP0100562A3 (en) 2002-08-28
FR2771291A1 (fr) 1999-05-28
NO20002605L (no) 2000-07-05
BG104511A (en) 2001-04-30
ATE246496T1 (de) 2003-08-15
EA003324B1 (ru) 2003-04-24
NO329728B1 (no) 2010-12-06
WO1999026608A1 (fr) 1999-06-03
JP2001523706A (ja) 2001-11-27
YU31000A (sh) 2002-11-15
AU744580B2 (en) 2002-02-28
IL136215A0 (en) 2001-05-20
BR9814672A (pt) 2000-10-03
PL340659A1 (en) 2001-02-12
CZ20001849A3 (cs) 2000-10-11
HRP20000323A2 (en) 2001-06-30
EA200000548A1 (ru) 2000-12-25
EP1032374B1 (fr) 2003-08-06
KR20010032329A (ko) 2001-04-16
CZ299110B6 (cs) 2008-04-23
CN1282239A (zh) 2001-01-31
CN1223341C (zh) 2005-10-19
NZ504662A (en) 2002-09-27
EP1032374A1 (fr) 2000-09-06
SK284493B6 (sk) 2005-05-05
HUP0100562A2 (hu) 2002-05-29
SK7562000A3 (en) 2001-06-11

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20061106

Year of fee payment: 9

PNAN Change of the applicant name, address/residence

Owner name: ETHYPHARM, FR

PBON Lapse due to non-payment of renewal fee

Effective date: 20071120