HN2009003214A - Compuestos de pirazina sustituidos - Google Patents
Compuestos de pirazina sustituidosInfo
- Publication number
- HN2009003214A HN2009003214A HN2009003214A HN2009003214A HN2009003214A HN 2009003214 A HN2009003214 A HN 2009003214A HN 2009003214 A HN2009003214 A HN 2009003214A HN 2009003214 A HN2009003214 A HN 2009003214A HN 2009003214 A HN2009003214 A HN 2009003214A
- Authority
- HN
- Honduras
- Prior art keywords
- pirazine
- substituted
- compounds
- conditions
- tautomers
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
UN COMPUESTO DE FORMULA I O LOS TAUTOMEROS, O ESTEREOISOMEROS, O SOLVATOS, O SALES FARMACÉUTICAMENTE ACEPTABLES DEL MISMO, EN DONDE M1, M2, L1, L2, W1, W2, X1, X2, Y1, Y2, A R5 Y R5A SON COMO SE DEFINEN EN LA PRESENTE, PARA EL TRATAMIENTO DE CONDICIONES TRATABLES MEDIANTE EL BLOQUEO DE UN CANAL DE SODIO EPITELIAL, EN PARTICULAR CONDICIONES QUE SE BENEFICIEN DE LA HIDRATACIÓN DE LA MUCOSA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07107654 | 2007-05-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
HN2009003214A true HN2009003214A (es) | 2012-03-05 |
Family
ID=38581916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HN2009003214A HN2009003214A (es) | 2007-05-07 | 2009-11-06 | Compuestos de pirazina sustituidos |
Country Status (32)
Country | Link |
---|---|
US (1) | US8318935B2 (es) |
EP (2) | EP2155721B1 (es) |
JP (1) | JP5244904B2 (es) |
KR (1) | KR20100005730A (es) |
CN (1) | CN101687851B (es) |
AR (1) | AR066458A1 (es) |
AT (1) | ATE499363T1 (es) |
AU (1) | AU2008248598B2 (es) |
BR (1) | BRPI0811562A2 (es) |
CA (1) | CA2685546A1 (es) |
CL (1) | CL2008001301A1 (es) |
CO (1) | CO6290667A2 (es) |
CR (1) | CR11091A (es) |
DE (1) | DE602008005140D1 (es) |
EA (1) | EA200901489A1 (es) |
EC (1) | ECSP099718A (es) |
ES (1) | ES2361595T3 (es) |
GT (1) | GT200900289A (es) |
HK (1) | HK1141285A1 (es) |
HN (1) | HN2009003214A (es) |
IL (1) | IL201828A0 (es) |
MA (1) | MA31400B1 (es) |
MX (1) | MX2009012077A (es) |
NZ (1) | NZ580737A (es) |
PE (1) | PE20090733A1 (es) |
PL (1) | PL2155721T3 (es) |
PT (1) | PT2155721E (es) |
SV (1) | SV2009003406A (es) |
TN (1) | TN2009000469A1 (es) |
TW (1) | TWI351402B (es) |
WO (1) | WO2008135557A1 (es) |
ZA (1) | ZA200907491B (es) |
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US8372845B2 (en) * | 2010-09-17 | 2013-02-12 | Novartis Ag | Pyrazine derivatives as enac blockers |
US9050339B2 (en) | 2010-09-17 | 2015-06-09 | Novartis Ag | Pyrazine derivatives as ENaC blockers |
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NO2773633T3 (es) * | 2011-11-02 | 2017-12-30 | ||
JP2015501324A (ja) * | 2011-11-02 | 2015-01-15 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | アシルグアニジン及びアシルチオ尿素の新規調製方法 |
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UY36034A (es) | 2014-03-18 | 2015-09-30 | Astrazeneca Ab | Derivados de 3,5-diamino-6-cloro-pirazina-2-carboxamida y sales farmaceuticamente aceptables de estos |
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JP6671378B2 (ja) * | 2015-01-12 | 2020-03-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 呼吸器系疾患の治療に有用な置換ベンズイミダゾリウム化合物 |
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