HK80784A - Powdery pharmaceutical composition and powdery preparation for application to the nasal mucosa,and method for administration thereof - Google Patents

Powdery pharmaceutical composition and powdery preparation for application to the nasal mucosa,and method for administration thereof

Info

Publication number
HK80784A
HK80784A HK807/84A HK80784A HK80784A HK 80784 A HK80784 A HK 80784A HK 807/84 A HK807/84 A HK 807/84A HK 80784 A HK80784 A HK 80784A HK 80784 A HK80784 A HK 80784A
Authority
HK
Hong Kong
Prior art keywords
powdery
administration
application
pharmaceutical composition
nasal mucosa
Prior art date
Application number
HK807/84A
Other languages
English (en)
Inventor
Yoshiki Suzuki
Ikura Hiroshi
Gentaro Yamashita
Tsuneji Nagai
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14171129&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK80784(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of HK80784A publication Critical patent/HK80784A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose

Landscapes

  • Health & Medical Sciences (AREA)
  • Otolaryngology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK807/84A 1979-07-31 1984-11-25 Powdery pharmaceutical composition and powdery preparation for application to the nasal mucosa,and method for administration thereof HK80784A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54096666A JPS6034925B2 (ja) 1979-07-31 1979-07-31 持続性鼻腔用製剤およびその製造法

Publications (1)

Publication Number Publication Date
HK80784A true HK80784A (en) 1984-11-25

Family

ID=14171129

Family Applications (1)

Application Number Title Priority Date Filing Date
HK807/84A HK80784A (en) 1979-07-31 1984-11-25 Powdery pharmaceutical composition and powdery preparation for application to the nasal mucosa,and method for administration thereof

Country Status (7)

Country Link
US (1) US4294829A (de)
EP (1) EP0023359B1 (de)
JP (1) JPS6034925B2 (de)
DE (1) DE3067536D1 (de)
HK (1) HK80784A (de)
MY (1) MY8600471A (de)
SG (1) SG52784G (de)

Families Citing this family (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU179164B (en) * 1979-12-14 1982-08-28 Egyt Gyogyszervegyeszeti Gyar Process for producing cycloalkyl-ethers of alkanolamines
EP0084190A3 (en) * 1981-12-08 1984-11-28 Fisons Plc Medicinal composition, package and method of making the composition
JPS58135805A (ja) * 1982-02-08 1983-08-12 Teijin Ltd アレルギー性鼻炎治療又は予防剤
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
GB8514090D0 (en) * 1985-06-04 1985-07-10 Sandoz Ltd Organic compounds
US4576646A (en) * 1983-07-06 1986-03-18 Seppic Film-forming compositions for enveloping solid forms, particularly pharmaceutical or food products or seeds, and products obtained, coated with said compositions
EP0187433B1 (de) * 1983-08-01 1990-12-27 Teijin Limited Pulverige pharmazeutische Zusammensetzung zur Anwendung auf die Schleimhaut der Mund- oder Nasenhöhle
JPS6032714A (ja) * 1983-08-01 1985-02-19 Teijin Ltd 鼻腔粘膜に適用するための安定化された粉末状薬学的組成物
JPS61194034A (ja) * 1985-02-25 1986-08-28 Teijin Ltd 経鼻投与用粉末状組成物
IT1187743B (it) * 1985-09-26 1987-12-23 Prodotti Formenti Srl Composizioni farmaceutiche a base di destrorfano per applicazione instranasale
EP0248051A1 (de) * 1985-11-29 1987-12-09 FISONS plc Natriumcromoglycat enthaltende pharmazeutische zusammensetzung
GB8618259D0 (en) * 1986-07-25 1986-09-03 Leo Pharm Prod Ltd Pharmaceutical compositions
DE3726517A1 (de) * 1986-08-18 1988-03-03 Sandoz Ag Nasale zusammensetzungen, welche octreotid enthalten
US4767612A (en) * 1987-01-23 1988-08-30 Rorer Pharmaceutical Corporation Triamcinolone acetonide for the treatment of allergic rhinitis
US5112804A (en) * 1987-04-01 1992-05-12 Temple University Of The Commonwealth System Of Higher Education Pharmaceutical composition and method of intranasal administration
US5059587A (en) * 1987-08-03 1991-10-22 Toyo Jozo Company, Ltd. Physiologically active peptide composition for nasal administration
GB8723846D0 (en) * 1987-10-10 1987-11-11 Danbiosyst Ltd Bioadhesive microsphere drug delivery system
ES2061688T3 (es) * 1987-11-13 1994-12-16 Smithkline Beecham Farma Composiciones farmaceuticas que comprenden una calcitonina y un glicirricinato como mejorador de la absorcion.
US5554388A (en) * 1989-02-25 1996-09-10 Danbiosyst Uk Limited Systemic drug delivery compositions comprising a polycationi substance
IT8920486A0 (it) * 1989-05-12 1989-05-12 Isf Spa Composizioni farmaceutiche.
US5776493A (en) * 1989-07-14 1998-07-07 Alza Corporation Oral osmotic device for delivery of nystatin with hydrogel driving member
GB2237510B (en) * 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
US5707644A (en) * 1989-11-04 1998-01-13 Danbiosyst Uk Limited Small particle compositions for intranasal drug delivery
JP2549935B2 (ja) * 1990-05-29 1996-10-30 三菱電機株式会社 信号処理装置
NL9002008A (nl) 1990-09-12 1992-04-01 Stichting Centr Diergeneeskund Recombinant dna en rna en daarvan afgeleide produkten.
US5248310A (en) * 1992-03-27 1993-09-28 Alza Corporation Oral osmotic device with hydrogel driving member
US5512299A (en) * 1992-03-30 1996-04-30 Alza Corporation Method of treating oral inflammatory disease
ATE158172T1 (de) * 1992-05-26 1997-10-15 Procter & Gamble Pulverförmige pharmazeutische zusammensetzung
ES2177544T3 (es) * 1992-06-12 2002-12-16 Teijin Ltd Polvo ultrafinno para inhalar y metodo para su preparacion.
WO1993025193A1 (en) * 1992-06-12 1993-12-23 Teijin Limited Pharmaceutical preparation for intra-airway administration
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US5573776A (en) * 1992-12-02 1996-11-12 Alza Corporation Oral osmotic device with hydrogel driving member
US6024090A (en) 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US7448375B2 (en) 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6794357B1 (en) 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
TW402506B (en) 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
US5747445A (en) * 1993-06-24 1998-05-05 Astra Aktiebolag Therapeutic preparation for inhalation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
IS1796B (is) * 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
DK0748213T3 (da) 1994-03-07 2004-08-02 Nektar Therapeutics Fremgangsmåder og sammensætninger til pulmonal indgivelse af insulin
US6165976A (en) 1994-06-23 2000-12-26 Astra Aktiebolag Therapeutic preparation for inhalation
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
EE9700138A (et) 1994-12-22 1997-12-15 Astra Aktiebolag Aerosoolravimvormid
ES2197212T3 (es) 1994-12-22 2004-01-01 Astrazeneca Ab Preparacion terapeutica para inhalacion que contiene la hormona paratiroidea, pth.
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
SE9404468D0 (sv) * 1994-12-22 1994-12-22 Astra Ab Powder formulations
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
US6428771B1 (en) * 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
US5879712A (en) * 1995-06-07 1999-03-09 Sri International Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced
KR100568436B1 (ko) * 1996-02-27 2007-04-25 데이진 가부시키가이샤 분말상경비투여조성물
US5976573A (en) * 1996-07-03 1999-11-02 Rorer Pharmaceutical Products Inc. Aqueous-based pharmaceutical composition
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
AU6014098A (en) 1996-12-31 1998-07-31 Inhale Therapeutic Systems Aerosolized hydrophobic drug
GB9700624D0 (en) 1997-01-14 1997-03-05 Danbiosyst Uk Drug delivery composition
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
US6264975B1 (en) 1998-10-20 2001-07-24 The University Of North Carolina At Chapel Hill Methods of hydrating mucosal surfaces
AU5936400A (en) 1999-06-04 2000-12-28 Delrx Pharmaceutical Corporation Formulations comprising dehydrated particles of pharmaceutical agents and process for preparing the same
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
WO2001000654A2 (en) * 1999-06-29 2001-01-04 Pharmaceutical Discovery Corporation Purification and stabilization of peptide and proteins in pharmaceutical agents
US6787164B2 (en) * 2000-02-23 2004-09-07 Bioselect Innovations, Inc. Composition and method for treating the effects of diseases and maladies
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
FR2832311B1 (fr) * 2001-11-21 2004-04-16 Besins Int Belgique Poudre filmogene, compositions la comprenant, leurs procedes de preparation et leurs utilisations
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
EP1894591B1 (de) 2002-03-20 2013-06-26 MannKind Corporation Kartusche für eine Inhalationsvorrichtung
US7582284B2 (en) 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
JP3691459B2 (ja) * 2002-06-14 2005-09-07 久光メディカル株式会社 粉末状吸入剤組成物
PT1663235E (pt) 2003-08-18 2013-10-29 Parion Sciences Inc Novos bloqueadores dos canais do sódio de pirazinoílguanidina protegida
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
US7338171B2 (en) * 2003-10-27 2008-03-04 Jen-Chuen Hsieh Method and apparatus for visual drive control
ES2584867T3 (es) * 2004-01-12 2016-09-29 Mannkind Corporation Un método que reduce los niveles séricos de proinsulina en diabéticos de tipo 2
JP2007520496A (ja) * 2004-02-04 2007-07-26 レットメッド ピーティーワイ リミテッド 徐放性ステロイド組成物
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
US20080248999A1 (en) * 2007-04-04 2008-10-09 Biodel Inc. Amylin formulations
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
CN104436170B (zh) 2004-08-23 2018-02-23 曼金德公司 用于药物输送的二酮哌嗪盐
BRPI0520505B1 (pt) * 2005-09-01 2015-03-31 José Luis Nuño Ayalá Fórmula estabilizadora de vacinas com antígenos vivos para uso em sistemas de vacinação em massa
HUE028623T2 (en) 2005-09-14 2016-12-28 Mannkind Corp Active substance formulation method based on increasing the affinity of the active ingredient for binding to the surface of crystalline microparticles
US20070086952A1 (en) * 2005-09-29 2007-04-19 Biodel, Inc. Rapid Acting and Prolonged Acting Inhalable Insulin Preparations
US8084420B2 (en) 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
IN2015DN00888A (de) 2006-02-22 2015-07-10 Mannkind Corp
EP2012817A2 (de) 2006-04-12 2009-01-14 Biodel, Inc. Insulinkombinationsformulierungen mit schneller wirkung und langzeitwirkung
ES2691033T3 (es) 2007-02-11 2018-11-23 Map Pharmaceuticals Inc. Método de administración terapéutica de DHE para activar el alivio rápido de la migraña a la vez que se reduce al mínimo el perfil de los efectos secundarios
NZ586940A (en) 2008-02-26 2012-08-31 Parion Sciences Inc Poly aromatic sodium channel blocker compounds comprising both pyrazine and guanidine moieties
US20090220386A1 (en) * 2008-02-29 2009-09-03 Ferri Joseph E Porous Sealing Material
ES2570400T3 (es) 2008-06-13 2016-05-18 Mannkind Corp Un inhalador de polvo seco y un sistema para el suministro de fármacos
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
EP2405963B1 (de) 2009-03-11 2013-11-06 MannKind Corporation Gerät, system und verfahren zur messung von widerstand in einem inhaliergerät
KR101875969B1 (ko) 2009-06-12 2018-07-06 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
MX359281B (es) 2010-06-21 2018-09-21 Mannkind Corp Sistema y metodos para suministrar un farmaco en polvo seco.
US9808030B2 (en) 2011-02-11 2017-11-07 Grain Processing Corporation Salt composition
MX353285B (es) 2011-04-01 2018-01-05 Mannkind Corp Paquete de blister para cartuchos farmaceuticos.
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
US9072738B2 (en) 2011-06-27 2015-07-07 Parion Sciences, Inc. Chemically and metabolically stable dipeptide possessing potent sodium channel blocker activity
CN103945859A (zh) 2011-10-24 2014-07-23 曼金德公司 用于治疗疼痛的方法和组合物
MX2014009598A (es) * 2012-02-10 2014-11-10 Dow Global Technologies Llc Composicion para cuerpos ceramicos moldeados por extrusion que comprende un derivado de celulosa de determinado largo medio de particula.
WO2014012069A2 (en) 2012-07-12 2014-01-16 Mannkind Corporation Dry powder drug delivery systems and methods
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
KR20150095870A (ko) 2012-12-17 2015-08-21 패리온 사이언스 인코퍼레이티드 3,5-디아미노-6-클로로-n-(n-(4-페닐부틸)카르밤이미도일)피라진-2-카르복스아미드 화합물
AU2013363218B2 (en) 2012-12-17 2018-03-15 Parion Sciences, Inc. Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration
AU2014228415B2 (en) 2013-03-15 2018-08-09 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
JP6356795B2 (ja) 2013-07-17 2018-07-11 ダウ グローバル テクノロジーズ エルエルシー メチルセルロースを含む粘膜適用組成物
KR102321339B1 (ko) 2013-07-18 2021-11-02 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods
EP3049060B1 (de) 2013-09-25 2017-10-25 Dow Global Technologies LLC Zusammensetzung zur anwendung auf einer schleimhaut mit einem celluloseether
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
GB201410250D0 (en) * 2014-06-10 2014-07-23 Nasaleze Patents Ltd Improvements to nasal compositions and method of use thereof
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
KR20210052281A (ko) * 2019-10-29 2021-05-10 신에쓰 가가꾸 고교 가부시끼가이샤 캡슐 충전용 조성물 및 이것을 사용한 캡슐 제제의 제조 방법 그리고 캡슐 제제

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1279214A (en) * 1970-01-22 1972-06-28 Forest Laboratories Long-acting oral carrier
GB1381872A (en) * 1971-06-22 1975-01-29 Fisons Ltd Pharmaceutical compositions for inhalation
US4013792A (en) * 1974-04-11 1977-03-22 Warner-Lambert Company Process for the production of base for topical steroids
GB1520247A (en) * 1974-08-10 1978-08-02 Fisons Ltd Pelletised medicament formulations
YU43437B (en) * 1976-05-05 1989-08-31 Lowey Hans Process for obtaining tablets containing an active component with long lasting effect
US4225597A (en) * 1976-10-01 1980-09-30 Schering Corporation Beclomethasone dipropionate-hexane solvate and aerosols prepared therefrom
GB1571629A (en) * 1977-11-30 1980-07-16 Fisons Ltd Pharmaceutical compositions containing beclomethasone dipropionate
GB2008945B (en) * 1977-12-01 1982-07-21 Welsh Nat School Med Apparatus and procedures and prepared pharmaceutical products for use in the administration of antihistamines

Also Published As

Publication number Publication date
JPS6034925B2 (ja) 1985-08-12
JPS5620509A (en) 1981-02-26
US4294829A (en) 1981-10-13
EP0023359A2 (de) 1981-02-04
EP0023359B1 (de) 1984-04-18
DE3067536D1 (en) 1984-05-24
SG52784G (en) 1985-03-08
EP0023359A3 (en) 1981-11-04
MY8600471A (en) 1986-12-31

Similar Documents

Publication Publication Date Title
DE3067536D1 (en) Powdery pharmaceutical composition and powdery preparation for application to the nasal mucosa, and method for administration thereof
DE3476633D1 (en) Powdery pharmaceutical composition for nasal administration
DE3268533D1 (en) Inhalation drugs, methods for their production and pharmaceutical formulations containing them
DE2962051D1 (en) Benzimidazoles, their preparation and pharmaceutical compositions containing them
IL69347A (en) Methylene-diphosphonic acid derivatives,their preparation and pharmaceutical compositions containing them
IL69601A0 (en) Naphthyridine-,quinoline-and benzoxazine-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
DE3366393D1 (en) Phospholipid derivatives, process for preparation thereof and pharmaceutical composition of the same
ZA794472B (en) Pyridazinone-substituted benzimidazoles,processes for their preparation,and pharmaceutical compositions thereof
DE2966142D1 (en) Quinolein-3-carboxylic acid derivatives, process for their preparation, their use in medicines and pharmaceutical compositions containing them
DE3273629D1 (en) New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof
IL57785A (en) Imidazoquinoxalines and their salts,process for their preparation,their use as medicaments and the pharmaceutical compositions containing them
IL56421A0 (en) 4-pyridone-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
DE2966364D1 (en) Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them
DE3277838D1 (en) Thiazolylurea derivatives, process for their preparation, and medicinal composition containing same
ZA793682B (en) New piperidylbenzimidazolinone derivatives,processes for their preparation and pharmaceutical compositions containing them
IL57219A (en) 10-methoxy-daunorubicin,10-methoxy-doxorubicin,their derivatives,preparation thereof,and pharmaceutical compositions comprising them
DE3176402D1 (en) Benzazol derivatives, processes for their preparation, their pharmaceutical composition and their application
DE2860796D1 (en) Tantomeric arylaminoimidazoline derivatives, their preparation and pharmaceutical formulations for analgetic application containing them
ZA823919B (en) Diazepin-10-ones,processes for their preparation,and pharmaceutical compositions thereof
IL56461A0 (en) 1-naphthyl-acetic acid derivatives, their preparation and pharmaceutical compositions containing them
MY8500403A (en) Ethsanolamine compounds, prolesses for their preparation, pharmaceutical preparations containing them and their medicinal use
IL57735A (en) 7beta-aminothiazolyl-acetamido-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
DE3267034D1 (en) Phospholipid derivatives, process for preparation thereof and pharmaceutical composition of the same
IL68520A (en) 5-oxo-2-pyrrolidinepropanoic acid and derivatives thereof,their preparation and pharmaceutical compositions containing them
ZA834917B (en) Phenylacetic acid derivatives,processes for their preparation,and pharmaceutical compositions thereof

Legal Events

Date Code Title Description
PE Patent expired