GB1279214A - Long-acting oral carrier - Google Patents

Long-acting oral carrier

Info

Publication number
GB1279214A
GB1279214A GB174471A GB174471A GB1279214A GB 1279214 A GB1279214 A GB 1279214A GB 174471 A GB174471 A GB 174471A GB 174471 A GB174471 A GB 174471A GB 1279214 A GB1279214 A GB 1279214A
Authority
GB
United Kingdom
Prior art keywords
weight
carrier
jan
long
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB174471A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forest Laboratories LLC
Original Assignee
Forest Laboratories LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forest Laboratories LLC filed Critical Forest Laboratories LLC
Publication of GB1279214A publication Critical patent/GB1279214A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

1279214 Sustained release compositions FOREST LABORATORIES INC 13 Jan 1971 [22 Jan 1970] 1744/71 Addition to 1171691 Heading A5B A pharmaceutical form for sustained buccal or sublingual administration consists of a shaped compressed product comprising a carrier of 100% to 80% by weight hydroxypropylmethyl cellulose and 0% to 20% by weight ethyl cellulose together with a therapeutically active ingredient, compressed at a pressure of 5 to 8 lbs./sq. inch in the presence of sufficient moisture as to provide the carrier with 5% to 25% by weight of water as dispersed moisture. The rate and duration of release of the active agent, which is either locally absorbed or swallowed in the saliva, is controlled by the size and shape of the product, and by the relative proportions of the two cellulose derivatives.
GB174471A 1970-01-22 1971-01-13 Long-acting oral carrier Expired GB1279214A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US514070A 1970-01-22 1970-01-22

Publications (1)

Publication Number Publication Date
GB1279214A true GB1279214A (en) 1972-06-28

Family

ID=21714381

Family Applications (1)

Application Number Title Priority Date Filing Date
GB174471A Expired GB1279214A (en) 1970-01-22 1971-01-13 Long-acting oral carrier

Country Status (1)

Country Link
GB (1) GB1279214A (en)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2190409A1 (en) * 1972-06-26 1974-02-01 Lowey Hans
US4122157A (en) 1977-03-04 1978-10-24 Richardson-Merrell Inc. Nitrofurantoin sustained release tablet
FR2459049A1 (en) * 1979-06-14 1981-01-09 Forest Laboratories PROCESS FOR THE PRODUCTION OF SHAPE PIECES FROM POWDERS CONSISTING OF SPHEROIDAL METAL PARTICLES
EP0023359A2 (en) * 1979-07-31 1981-02-04 Teijin Limited Powdery pharmaceutical composition and powdery preparation for application to the nasal mucosa, and method for administration thereof
US4292300A (en) 1976-07-23 1981-09-29 Inveresk Research International Controlled release suppositories
US4357469A (en) 1979-06-14 1982-11-02 Forest Laboratories, Inc. Carrier base material for prolonged release therapeutic compositions
US4680323A (en) * 1983-12-01 1987-07-14 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration
US4775535A (en) * 1986-04-04 1988-10-04 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
FR2619717A1 (en) * 1987-09-02 1989-03-03 Medibrevex NEW GALENIC FORMS OF INSULIN FOR PER- AND SUBLINGUAL DELIVERY
US4855143A (en) * 1986-04-04 1989-08-08 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
GB2219206A (en) * 1988-02-03 1989-12-06 Ddsa Pharmaceuticals Ltd Sustained release medicinal formulations containing cellulose ethers
US5098691A (en) * 1991-05-06 1992-03-24 Colgate-Palmolive Company Composition for disclosing dental plaque
US5190743A (en) * 1991-05-06 1993-03-02 Colgate-Palmolive Company Composition for disclosing dental plaque
WO1999040898A2 (en) * 1998-02-12 1999-08-19 Centrapharm Inc. Sublingual drug formulations having combined rapid onset of action and long lasting therapeutic effect
WO2001045678A2 (en) * 1999-12-21 2001-06-28 Id Pharma Gmbh Medicament, a method for its production and the use thereof

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2190409A1 (en) * 1972-06-26 1974-02-01 Lowey Hans
US4292300A (en) 1976-07-23 1981-09-29 Inveresk Research International Controlled release suppositories
US4122157A (en) 1977-03-04 1978-10-24 Richardson-Merrell Inc. Nitrofurantoin sustained release tablet
FR2459049A1 (en) * 1979-06-14 1981-01-09 Forest Laboratories PROCESS FOR THE PRODUCTION OF SHAPE PIECES FROM POWDERS CONSISTING OF SPHEROIDAL METAL PARTICLES
US4357469A (en) 1979-06-14 1982-11-02 Forest Laboratories, Inc. Carrier base material for prolonged release therapeutic compositions
EP0023359A2 (en) * 1979-07-31 1981-02-04 Teijin Limited Powdery pharmaceutical composition and powdery preparation for application to the nasal mucosa, and method for administration thereof
EP0023359A3 (en) * 1979-07-31 1981-11-04 Teijin Limited Powdery pharmaceutical composition and powdery preparation for application to the nasal mucosa, and method for administration thereof
US4680323A (en) * 1983-12-01 1987-07-14 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration
US4775535A (en) * 1986-04-04 1988-10-04 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
US4855143A (en) * 1986-04-04 1989-08-08 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
FR2619717A1 (en) * 1987-09-02 1989-03-03 Medibrevex NEW GALENIC FORMS OF INSULIN FOR PER- AND SUBLINGUAL DELIVERY
EP0306421A1 (en) * 1987-09-02 1989-03-08 Medibrevex Sa Galenical insulin forms for per- and sublingual administration
GB2219206A (en) * 1988-02-03 1989-12-06 Ddsa Pharmaceuticals Ltd Sustained release medicinal formulations containing cellulose ethers
US5098691A (en) * 1991-05-06 1992-03-24 Colgate-Palmolive Company Composition for disclosing dental plaque
US5190743A (en) * 1991-05-06 1993-03-02 Colgate-Palmolive Company Composition for disclosing dental plaque
WO1999040898A2 (en) * 1998-02-12 1999-08-19 Centrapharm Inc. Sublingual drug formulations having combined rapid onset of action and long lasting therapeutic effect
WO1999040898A3 (en) * 1998-02-12 1999-11-04 Centrapharm Inc Sublingual drug formulations having combined rapid onset of action and long lasting therapeutic effect
WO2001045678A2 (en) * 1999-12-21 2001-06-28 Id Pharma Gmbh Medicament, a method for its production and the use thereof
WO2001045678A3 (en) * 1999-12-21 2002-04-11 Id Pharma Gmbh Medicament, a method for its production and the use thereof

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Legal Events

Date Code Title Description
PS Patent sealed
PE Patent expired