ES430431A1 - Direct compression tabletting composition and pharmaceutical tablets produced therefrom - Google Patents

Direct compression tabletting composition and pharmaceutical tablets produced therefrom

Info

Publication number
ES430431A1
ES430431A1 ES430431A ES430431A ES430431A1 ES 430431 A1 ES430431 A1 ES 430431A1 ES 430431 A ES430431 A ES 430431A ES 430431 A ES430431 A ES 430431A ES 430431 A1 ES430431 A1 ES 430431A1
Authority
ES
Spain
Prior art keywords
direct compression
produced therefrom
pharmaceutical tablets
tablets produced
vehicle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES430431A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Electric Co
Original Assignee
General Electric Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Electric Co filed Critical General Electric Co
Publication of ES430431A1 publication Critical patent/ES430431A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C13SUGAR INDUSTRY
    • C13BPRODUCTION OF SUCROSE; APPARATUS SPECIALLY ADAPTED THEREFOR
    • C13B50/00Sugar products, e.g. powdered, lump or liquid sugar; Working-up of sugar
    • C13B50/002Addition of chemicals or other foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • CCHEMISTRY; METALLURGY
    • C13SUGAR INDUSTRY
    • C13BPRODUCTION OF SUCROSE; APPARATUS SPECIALLY ADAPTED THEREFOR
    • C13B50/00Sugar products, e.g. powdered, lump or liquid sugar; Working-up of sugar
    • C13B50/02Sugar products, e.g. powdered, lump or liquid sugar; Working-up of sugar formed by moulding sugar

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Method for producing a direct compression vehicle for tabletting which involves admixing a crystalline sugar with a maltodextrin and spraying the admixture with an aqueous solution of a maltodextrin. The resulting vehicle may be combined with a pharmaceutically active ingredient wherein the pharmaceutically active ingredient may be present in an amount of up to 80% of the weight of the vehicle. The resulting pharmaceutical composition can be compressed into a tablet having a Strong Cobb Hardness Unit (S.C.H.U.) value of at least about 6.
ES430431A 1973-09-27 1974-09-26 Direct compression tabletting composition and pharmaceutical tablets produced therefrom Expired ES430431A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US401322A US3873694A (en) 1973-09-27 1973-09-27 Direct compression tabletting composition and pharmaceutical tablets produced therefrom

Publications (1)

Publication Number Publication Date
ES430431A1 true ES430431A1 (en) 1976-10-01

Family

ID=23587269

Family Applications (1)

Application Number Title Priority Date Filing Date
ES430431A Expired ES430431A1 (en) 1973-09-27 1974-09-26 Direct compression tabletting composition and pharmaceutical tablets produced therefrom

Country Status (5)

Country Link
US (1) US3873694A (en)
JP (1) JPS5058219A (en)
ES (1) ES430431A1 (en)
GB (1) GB1471564A (en)
MY (1) MY7800034A (en)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2822324C3 (en) * 1978-05-22 1981-02-26 Basf Ag, 6700 Ludwigshafen Manufacture of vitamin E dry powder
US4349542A (en) * 1979-06-08 1982-09-14 National Research Development Corporation Mixture containing active ingredient and dendritic crystalline sugar for tableting
SE7905972L (en) * 1979-07-09 1981-01-10 Haessle Ab PROCEDURE FOR THE PREPARATION OF Gastric Acid-Neutralizing Agents, Gastric Acid-Neutralizing Agents, AND METHOD OF TREATING HYPERACIDITY AND RELATED DISEASE CONDITIONS
AR226763A1 (en) * 1980-12-22 1982-08-13 Monsanto Co PREPARATION METHOD FOR AN ANALGESIC GRANULATION OF ACETAMINOPHEN
GR79340B (en) * 1982-07-06 1984-10-22 Sterwin Ag
US4495177A (en) * 1983-01-17 1985-01-22 Shaklee Corporation Gel tableting agent
US4643894A (en) * 1984-07-24 1987-02-17 Colorcon, Inc. Maltodextrin coating
US4639458A (en) * 1985-01-22 1987-01-27 Merck & Co., Inc. Tablet and formulation
US4684534A (en) * 1985-02-19 1987-08-04 Dynagram Corporation Of America Quick-liquifying, chewable tablet
US4711894A (en) * 1986-01-16 1987-12-08 Henkel Corporation Stabilized tocopherol in dry, particulate, free-flowing form
FR2613619B1 (en) * 1987-04-07 1993-10-15 Recherche Informatique Pharmacie DRUGS, DIETETIC PRODUCTS OR HYGIENE PRODUCTS IN THE FORM OF POWDER COMPOSITIONS OBTAINED BY ADSORPTION OF ACTIVE INGREDIENTS ON A FAST-DISSOLVING SUGAR
US4894236A (en) * 1988-01-12 1990-01-16 Choong-Gook Jang Direct compression tablet binders for acetaminophen
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
NZ232346A (en) * 1989-02-07 1992-03-26 Duphar Int Res Effervescent oral rehydration solution comprising saccharides, amino acids and bicarbonate salts
US5130140A (en) * 1989-09-14 1992-07-14 Hoeschst-Roussel Pharmaceuticals Inc. Method of making direct dry compressible acetaminophen composition
US5198228A (en) * 1989-09-14 1993-03-30 Hoechst-Roussel Pharmaceuticals Inc. Direct dry compressible acetaminophen tablet
US5037658A (en) * 1989-09-14 1991-08-06 Hoechst-Roussel Pharmaceuticals, Inc. Direct dry compressible acetaminophen composition
DE69121098T2 (en) * 1990-04-04 1997-01-23 Berwind Pharma Service AQUEOUS FILM-FORMING COATING COMPOSITIONS MALTODEXTRIN AND CELLULOSE DERIVATIVES
JP2542122B2 (en) * 1990-04-18 1996-10-09 旭化成工業株式会社 Spherical nucleus, spherical granule and method for producing the same
DE69111287T2 (en) * 1990-04-18 1995-12-21 Asahi Chemical Ind Spherical nuclei, spherical granules and processes for their production.
US5531983A (en) * 1990-10-08 1996-07-02 Purac Biochem B.V. Oral hygiene preparation
SE9301220D0 (en) * 1993-04-14 1993-04-14 Kabi Pharmacia Ab MANUFACTURING MATRICES
US5424289A (en) * 1993-07-30 1995-06-13 Alza Corporation Solid formulations of therapeutic proteins for gastrointestinal delivery
EP0745382B1 (en) * 1994-01-31 2003-11-12 Yamanouchi Pharmaceutical Co. Ltd. Intraorally soluble compressed molding and process for producing the same
US5798388A (en) * 1996-09-06 1998-08-25 Cellular Sciences, Inc. Method and composition for treating mammalian diseases caused by inflammatory response
US6080427A (en) * 1997-04-17 2000-06-27 Bristol-Myers Squibb Company Cefadroxil monohydrate tablet formulation
FR2769636B1 (en) * 1997-10-13 2000-01-28 Saint Louis Sucre Sa SACCHAROSE-BASED HYDROPHOBIC PRODUCT
US6348264B1 (en) 1998-04-27 2002-02-19 Roquette Freres Process for producing low de starch hydrolysates by nanofiltration fractionation, products obtained thereby, and use of such products
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6716453B1 (en) * 1999-05-20 2004-04-06 Verion, Inc. Method for increasing the active loading of compressible composition forms
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
AU2002225763A1 (en) 2000-11-28 2002-06-11 Fmc Corporation Edible pga(propylene glycol alginate) coating composition
US6932861B2 (en) 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
US20050143343A1 (en) * 2003-12-30 2005-06-30 Nerenberg Arnold P. Nutritional supplement for enhancing the production and effect of natural human growth hormone
US20080069936A1 (en) * 2006-09-18 2008-03-20 ISON Renny Cohesive non-free flowing sweeetener compositions containing a hygroscopic gluing agent and a desiccant
US20120034302A1 (en) * 2009-02-11 2012-02-09 Liangping Yu Particulate composition and the method of making the same
MX339772B (en) * 2010-08-13 2016-06-09 Rdm Empreendimentos E Participações S A * Method and composition for reducing the color of sugar.
EA201992382A3 (en) 2013-03-15 2020-05-31 Брейнтри Лабораторис, Инк. ORAL TABLET PHARMACEUTICAL COMPOSITION FOR DOUBLE USE ON THE BASIS OF SULPHATE SALTS AND METHODS OF ITS APPLICATION
DE202015004009U1 (en) 2015-06-09 2016-01-11 Hermes Arzneimittel Gmbh Fast disintegrating tablets without decay accelerator
DE202016005032U1 (en) 2016-08-19 2017-02-10 Hermes Arzneimittel Gmbh Fast disintegrating Ivy drinking tablets without decay accelerator
US10143656B1 (en) 2017-08-04 2018-12-04 Braintree Laboratories, Inc. Solid oral sulfate salt formulations for cleaning a colon and methods of using same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3140201A (en) * 1962-01-09 1964-07-07 American Sugar Dry pulverulent sugar products and process for producing same
US3169888A (en) * 1962-03-05 1965-02-16 American Sugar Pressed crystal sugar tablet and method of manufacturing same
US3305447A (en) * 1963-06-12 1967-02-21 American Sugar Tabletting sugar and method of preparing same
US3619292A (en) * 1968-07-15 1971-11-09 Penick & Ford Ltd Tablets and method of forming
US3589909A (en) * 1968-10-31 1971-06-29 Corn Products Co Gum confections containing dextrose and 5-15 d. e. starch hydrolysate
US3639168A (en) * 1969-04-29 1972-02-01 Sucrest Corp Direct compression vehicles
US3639169A (en) * 1969-04-29 1972-02-01 Sucrest Corp Direct compression vehicles and method therefor
US3627583A (en) * 1969-04-29 1971-12-14 Sucrest Corp Direct compression vehicles
US3642535A (en) * 1970-01-21 1972-02-15 American Sugar Tabletting sugar, method of preparing compositions containing same

Also Published As

Publication number Publication date
MY7800034A (en) 1978-12-31
GB1471564A (en) 1977-04-27
JPS5058219A (en) 1975-05-21
US3873694A (en) 1975-03-25

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