HK4588A - Anti-tumor quinazoline compounds - Google Patents

Anti-tumor quinazoline compounds

Info

Publication number
HK4588A
HK4588A HK45/88A HK4588A HK4588A HK 4588 A HK4588 A HK 4588A HK 45/88 A HK45/88 A HK 45/88A HK 4588 A HK4588 A HK 4588A HK 4588 A HK4588 A HK 4588A
Authority
HK
Hong Kong
Prior art keywords
tumor
quinazoline compounds
quinazoline
compounds
tumor quinazoline
Prior art date
Application number
HK45/88A
Other languages
English (en)
Inventor
William E Kreighbaum
William T Comer
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of HK4588A publication Critical patent/HK4588A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/74Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK45/88A 1981-03-06 1988-01-21 Anti-tumor quinazoline compounds HK4588A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/241,317 US4343940A (en) 1979-02-13 1981-03-06 Anti-tumor quinazoline compounds

Publications (1)

Publication Number Publication Date
HK4588A true HK4588A (en) 1988-01-29

Family

ID=22910195

Family Applications (1)

Application Number Title Priority Date Filing Date
HK45/88A HK4588A (en) 1981-03-06 1988-01-21 Anti-tumor quinazoline compounds

Country Status (31)

Country Link
US (1) US4343940A (ja)
JP (1) JPS57158780A (ja)
KR (1) KR880001852B1 (ja)
AR (1) AR231138A1 (ja)
AT (1) AT380476B (ja)
AU (1) AU556099B2 (ja)
BE (1) BE891936A (ja)
CA (1) CA1163995A (ja)
CH (1) CH647776A5 (ja)
CY (1) CY1371A (ja)
DE (1) DE3203770C2 (ja)
DK (1) DK159442C (ja)
ES (1) ES8304095A1 (ja)
FI (1) FI71559C (ja)
FR (1) FR2501207B1 (ja)
GB (1) GB2094295B (ja)
GR (1) GR75903B (ja)
HK (1) HK4588A (ja)
HU (1) HU189997B (ja)
IE (1) IE52385B1 (ja)
IL (1) IL64875A0 (ja)
IT (1) IT1154272B (ja)
KE (1) KE3715A (ja)
LU (1) LU83903A1 (ja)
NL (1) NL8200473A (ja)
NZ (1) NZ199576A (ja)
PH (1) PH18529A (ja)
PT (1) PT74394B (ja)
SE (1) SE461732B (ja)
SG (1) SG30787G (ja)
YU (1) YU42031B (ja)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3131365A1 (de) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
US4963554A (en) * 1990-02-14 1990-10-16 Ortho Pharmaceutical Corporation 6,7-dimethoxy-1,2-dihydro-2-arylquinazoline-3-oxides
US5030635A (en) * 1990-02-14 1991-07-09 Ortho Pharmaceutical Corporation 6-7-dimethoxy-1,2-dihydro-2-arylquinazoline-3-oxides
US6645969B1 (en) 1991-05-10 2003-11-11 Aventis Pharmaceuticals Inc. Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
US5480883A (en) * 1991-05-10 1996-01-02 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
US5714493A (en) * 1991-05-10 1998-02-03 Rhone-Poulenc Rorer Pharmaceuticals, Inc. Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
US5710158A (en) * 1991-05-10 1998-01-20 Rhone-Poulenc Rorer Pharmaceuticals Inc. Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
USRE37650E1 (en) 1991-05-10 2002-04-09 Aventis Pharmacetical Products, Inc. Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
PT100905A (pt) * 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
DE69422450T2 (de) * 1993-06-29 2000-06-08 Takeda Chemical Industries Ltd Chinoline oder Chinazolin-Derivate und deren Verwendung zur Herstellung eines Medikaments für die Behandlung von Osteoporose
US5804396A (en) * 1994-10-12 1998-09-08 Sugen, Inc. Assay for agents active in proliferative disorders
TW321649B (ja) * 1994-11-12 1997-12-01 Zeneca Ltd
GB9424233D0 (en) * 1994-11-30 1995-01-18 Zeneca Ltd Quinazoline derivatives
US5837815A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polypeptide products
US5837524A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polynucleotide products
GB9508537D0 (en) * 1995-04-27 1995-06-14 Zeneca Ltd Quinazoline derivatives
GB9508565D0 (en) * 1995-04-27 1995-06-14 Zeneca Ltd Quiazoline derivative
GB9508535D0 (en) * 1995-04-27 1995-06-14 Zeneca Ltd Quinazoline derivative
DE69613367T2 (de) * 1995-04-27 2002-04-18 Astrazeneca Ab Chinazolin derivate
GB9508538D0 (en) * 1995-04-27 1995-06-14 Zeneca Ltd Quinazoline derivatives
EP0832073B1 (en) * 1995-06-07 2002-01-16 Sugen, Inc. Quinazolines and pharmaceutical compositions
AU7340096A (en) * 1995-11-07 1997-05-29 Kirin Beer Kabushiki Kaisha Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same
US6716575B2 (en) 1995-12-18 2004-04-06 Sugen, Inc. Diagnosis and treatment of AUR1 and/or AUR2 related disorders
US7119174B2 (en) * 1995-12-18 2006-10-10 Sugen, Inc. Diagnosis and treatment of AUR1 and/or AUR2 related disorders
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
SK285141B6 (sk) 1996-02-13 2006-07-07 Astrazeneca Uk Limited Použitie chinazolínového derivátu, chinazolínový derivát, spôsob jeho prípravy a farmaceutická kompozícia, ktorá ho obsahuje
GB9603097D0 (en) * 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline compounds
GB9603095D0 (en) * 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline derivatives
EP0885198B1 (en) 1996-03-05 2001-12-19 AstraZeneca AB 4-anilinoquinazoline derivatives
GB9607729D0 (en) * 1996-04-13 1996-06-19 Zeneca Ltd Quinazoline derivatives
GB9718972D0 (en) * 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
ES2227729T3 (es) * 1996-12-11 2005-04-01 Sugen, Inc. Metodos de cribaje para compuestos unidos al polipeptido pyk2.
US6818440B2 (en) * 1997-04-28 2004-11-16 Sugen, Inc. Diagnosis and treatment of alk-7 related disorders
US6228641B1 (en) 1997-05-20 2001-05-08 Sugen, Inc. Diagnosis and treatment of PTP04 related disorders
US6342593B1 (en) 1997-06-11 2002-01-29 Sugen, Inc. Diagnosis and treatment of ALP related disorders
US7115710B2 (en) * 1997-06-11 2006-10-03 Sugen, Inc. Diagnosis and treatment of PTP related disorders
US6388063B1 (en) 1997-06-18 2002-05-14 Sugen, Inc. Diagnosis and treatment of SAD related disorders
AU2237899A (en) * 1998-01-21 1999-08-09 Sugen, Inc. Human orthologues of wart
EP1073723B1 (en) * 1998-04-14 2005-08-17 Sugen, Inc. Ste20-related protein kinases
WO1999061428A1 (en) 1998-05-28 1999-12-02 Parker Hughes Institute Quinazolines for treating brain tumor
US6800649B1 (en) 1998-06-30 2004-10-05 Parker Hughes Institute Method for inhibiting c-jun expression using JAK-3 inhibitors
AU5682799A (en) * 1998-08-21 2000-03-14 Parker Hughes Institute Quinazoline derivatives
US6861442B1 (en) 1998-12-30 2005-03-01 Sugen, Inc. PYK2 and inflammation
US6080747A (en) * 1999-03-05 2000-06-27 Hughes Institute JAK-3 inhibitors for treating allergic disorders
US6258820B1 (en) 1999-03-19 2001-07-10 Parker Hughes Institute Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines
US7364866B2 (en) * 1999-10-22 2008-04-29 Pharmacia & Upjohn Company Drosophila G protein coupled receptors, nucleic acids, and methods related to the same
US20030162223A1 (en) * 1999-10-22 2003-08-28 Lowery David E. Drosophila G protein coupled receptors, nucleic acids, and methods related to the same
WO2001031005A2 (en) * 1999-10-22 2001-05-03 Pharmacia & Upjohn Company Drosophila g protein coupled receptors, nucleic acids, and methods related to the same
ES2306306T3 (es) 1999-11-05 2008-11-01 Astrazeneca Ab Nuevos derivados de quinazolina.
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors
US20030082534A1 (en) * 1999-11-16 2003-05-01 Peter Lind Novel G protein-coupled receptors
EP1265925A2 (en) * 2000-02-23 2002-12-18 PHARMACIA & UPJOHN COMPANY G protein-coupled receptors
US7160889B2 (en) * 2000-04-07 2007-01-09 Astrazeneca Ab Quinazoline compounds
US20050069976A1 (en) * 2001-02-14 2005-03-31 Peter Lind Protein-coupled receptor
JP4726486B2 (ja) 2002-08-02 2011-07-20 アブ サイエンス 2−(3−アミノアリール)アミノ−4−アリール−チアゾールおよびそれらのc−kit阻害薬としての使用法
US8450302B2 (en) * 2002-08-02 2013-05-28 Ab Science 2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors
NZ546645A (en) * 2003-10-23 2010-02-26 Ab Science 2-Aminoaryloxazole compounds as tyrosine kinase inhibitors
UA95071C2 (ru) 2005-04-04 2011-07-11 Аб Сьянс Замещенные производные оксазола и их применение как ингибиторов тирозинкиназы
US8246966B2 (en) * 2006-08-07 2012-08-21 University Of Georgia Research Foundation, Inc. Trypanosome microsome system and uses thereof
AU2007303846B2 (en) 2006-10-04 2011-03-10 Pfizer Products Inc. Pyrido[4,3-d]pyrimidin-4(3H)-one derivatives as calcium receptor antagonists
CA2669531A1 (en) * 2006-11-22 2008-06-05 University Of Georgia Research Foundation, Inc. Tyrosine kinase inhibitors as anti-kinetolastid and anti-apicomplexan agents
WO2008066498A1 (en) * 2006-12-01 2008-06-05 Agency For Science, Technology And Research Cancer-related protein kinases
KR20220031732A (ko) 2011-03-04 2022-03-11 뉴젠 세러퓨틱스 인코포레이티드 알킨 치환된 퀴나졸린 화합물 및 그것의 사용 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3298291A (en) * 1965-12-28 1967-01-17 Jack D Layton Paver screed assembly
US3455920A (en) * 1967-01-13 1969-07-15 Squibb & Sons Inc 2,3-dihydro-5 and 6-substituted-2-phenyl-4(1h)-quinazolinones
US3637693A (en) * 1968-07-12 1972-01-25 Du Pont Hydroxyarylquinazolines and their use as uv-absorbers
DE2050092C3 (de) 1970-10-13 1980-04-24 Bayer Ag, 5090 Leverkusen Chinazolondiurethane, Verfahren zu ihrer Herstellung sowie Arzneimittel, die diese Verbindungen enthalten
DE2162327C3 (de) * 1970-12-23 1975-09-18 Sumitomo Chemical Co., Ltd., Osaka (Japan) Verfahren zur Herstellung von 3,4-Oihydro-2(1 H)-chinazolinonen
US4080455A (en) * 1975-12-16 1978-03-21 Taisho Pharmaceutical Company Limited 5-Fluoropyrimidin-4-one compositions
JPS6011032B2 (ja) 1975-12-16 1985-03-22 大鵬薬品工業株式会社 2―置換―5―フルオルピリミジン―4―オン誘導体の製造法

Also Published As

Publication number Publication date
JPS57158780A (en) 1982-09-30
NZ199576A (en) 1986-05-09
DK159442C (da) 1991-03-18
SE8200526L (sv) 1982-09-07
SG30787G (en) 1988-09-16
US4343940A (en) 1982-08-10
GB2094295A (en) 1982-09-15
PT74394A (en) 1982-03-01
IT8247713A0 (it) 1982-02-03
ATA39582A (de) 1985-10-15
DE3203770C2 (de) 1993-11-04
BE891936A (fr) 1982-07-28
DK159442B (da) 1990-10-15
ES509434A0 (es) 1983-02-16
IL64875A0 (en) 1982-03-31
KE3715A (en) 1987-04-16
GB2094295B (en) 1984-09-12
SE461732B (sv) 1990-03-19
CY1371A (en) 1987-08-07
PH18529A (en) 1985-08-02
HU189997B (en) 1986-08-28
FI71559B (fi) 1986-10-10
NL8200473A (nl) 1982-10-01
FR2501207B1 (fr) 1985-12-06
ES8304095A1 (es) 1983-02-16
FI71559C (fi) 1987-01-19
CH647776A5 (de) 1985-02-15
FR2501207A1 (fr) 1982-09-10
FI820399L (fi) 1982-09-07
AU556099B2 (en) 1986-10-23
IE52385B1 (en) 1987-10-14
LU83903A1 (fr) 1982-09-13
DK50482A (da) 1982-09-07
YU42031B (en) 1988-04-30
KR880001852B1 (ko) 1988-09-22
AU7998182A (en) 1982-09-09
DE3203770A1 (de) 1982-11-11
CA1163995A (en) 1984-03-20
JPH0337552B2 (ja) 1991-06-05
IT1154272B (it) 1987-01-21
AT380476B (de) 1986-05-26
PT74394B (en) 1984-10-22
AR231138A1 (es) 1984-09-28
GR75903B (ja) 1984-08-02
YU25682A (en) 1985-03-20
IE820163L (en) 1982-09-06
KR830009050A (ko) 1983-12-17

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