HK25892A - Aromatic compounds - Google Patents

Aromatic compounds

Info

Publication number
HK25892A
HK25892A HK258/92A HK25892A HK25892A HK 25892 A HK25892 A HK 25892A HK 258/92 A HK258/92 A HK 258/92A HK 25892 A HK25892 A HK 25892A HK 25892 A HK25892 A HK 25892A
Authority
HK
Hong Kong
Prior art keywords
formula
compound
enyl
pyrrolidino
prop
Prior art date
Application number
HK258/92A
Other languages
German (de)
English (en)
French (fr)
Inventor
Geoffrey George Coker
John William Addison Findlay
Original Assignee
The Wellcome Foundation Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Wellcome Foundation Limited filed Critical The Wellcome Foundation Limited
Publication of HK25892A publication Critical patent/HK25892A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Polyesters Or Polycarbonates (AREA)
HK258/92A 1982-02-04 1992-04-09 Aromatic compounds HK25892A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8203261 1982-02-04
GB8229705 1982-10-18

Publications (1)

Publication Number Publication Date
HK25892A true HK25892A (en) 1992-04-16

Family

ID=26281898

Family Applications (1)

Application Number Title Priority Date Filing Date
HK258/92A HK25892A (en) 1982-02-04 1992-04-09 Aromatic compounds

Country Status (32)

Country Link
EP (2) EP0249950B1 (en:Method)
JP (2) JPS6479153A (en:Method)
KR (6) KR880001466B1 (en:Method)
AT (2) ATE42282T1 (en:Method)
AU (1) AU555083B2 (en:Method)
BG (6) BG42185A3 (en:Method)
CA (2) CA1249830A (en:Method)
CS (1) CS235306B2 (en:Method)
CY (1) CY1627A (en:Method)
DD (1) DD209446A5 (en:Method)
DE (2) DE3379654D1 (en:Method)
DK (1) DK164662C (en:Method)
ES (6) ES8403872A1 (en:Method)
FI (1) FI82450C (en:Method)
GB (1) GB2114565B (en:Method)
GR (1) GR77407B (en:Method)
HK (1) HK25892A (en:Method)
HU (1) HU189223B (en:Method)
IE (1) IE54600B1 (en:Method)
IL (3) IL67829A (en:Method)
MC (1) MC1498A1 (en:Method)
NL (1) NL930057I2 (en:Method)
NO (2) NO162556C (en:Method)
NZ (1) NZ203171A (en:Method)
PH (1) PH21348A (en:Method)
PL (6) PL140809B1 (en:Method)
PT (1) PT76192B (en:Method)
SG (1) SG106091G (en:Method)
SI (1) SI8310221A8 (en:Method)
SU (1) SU1301312A3 (en:Method)
UY (1) UY23404A1 (en:Method)
YU (1) YU44821B (en:Method)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562258A (en) * 1982-02-04 1985-12-31 Findlay John W A 6-[3-Amino-1-(4-tolyl)prop-1E-enyl]pyridine-2-carboxylic acid derivatives having antihistaminic activity
US4610995A (en) * 1984-07-27 1986-09-09 Coker Geoffrey G Certain 1,1-diaryl-propenyl-3-(1-pyrrolidino-2-carboxylic acids, derivatives thereof and their anti-histaminic properties
LU86387A1 (fr) * 1986-04-04 1987-12-07 Oreal Composes aromatiques,leur procede de preparation et leur utilisation en medicine humaine et veterinaire et en cosmetique
GB8707416D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
DE3711866A1 (de) * 1987-04-08 1988-10-27 Hoechst Ag Synthese von peptidamiden mittels festphasenmethode unter verwendung von saeurelabilen ankergruppen
GB8914040D0 (en) * 1989-06-19 1989-08-09 Wellcome Found Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
HUT59377A (en) * 1989-06-19 1992-05-28 Wellcome Found Process for producing drugs containing new aromatic rings
GB8914060D0 (en) * 1989-06-19 1989-08-09 Wellcome Found Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
FR2711651B1 (fr) * 1993-10-28 1995-12-22 Adir Nouveaux analogues cyclisés de métabolites d'acides gras, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
US5420866A (en) * 1994-03-29 1995-05-30 Scientific-Atlanta, Inc. Methods for providing conditional access information to decoders in a packet-based multiplexed communications system
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
AU698487B2 (en) * 1995-08-05 1998-10-29 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives
IT1277597B1 (it) 1995-09-15 1997-11-11 Smithkline Beecham Spa Derivati di diarilalchenilammina
JP2002212167A (ja) * 2001-01-22 2002-07-31 Nippon Nohyaku Co Ltd ジアセチルピリジン誘導体の製造方法
CN101838235B (zh) * 2009-06-12 2013-08-07 重庆华邦制药有限公司 3-苯基-3＇-吡啶基丙烯胺类化合物及其合成方法
WO2012038521A1 (en) * 2010-09-23 2012-03-29 Syngenta Participations Ag Novel microbiocides
CN104254589B (zh) 2012-04-23 2016-06-15 沙特基础工业公司 基于太阳能的连续方法和用于通过相应的烷烃脱氢生产烯烃的反应器系统

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2567245A (en) * 1948-05-10 1951-09-11 Schering Corp Aryl-(2-pyridyl)-amino alkanes and their production
DE1227464B (de) * 1951-09-10 1966-10-27 Wellcome Found Verfahren zur Herstellung der trans-Form des neuen 1-(4'-Methylphenyl)-1-(2''-pyridyl)-3-pyrrolidinopropens-(1)
FR1228802A (fr) * 1954-05-03 1960-09-02 Farbwerke Hoechst Ag Vomals Me Procédé de préparation de composés tertio-amino-cétoniques
FR2197583B1 (en:Method) * 1972-09-07 1975-10-17 Rhone Poulenc Ind

Also Published As

Publication number Publication date
PL140812B1 (en) 1987-05-30
PL140708B1 (en) 1987-05-30
JPH0251897B2 (en:Method) 1990-11-08
BG41821A3 (en) 1987-08-14
NZ203171A (en) 1986-12-05
AU1098283A (en) 1983-08-11
YU22183A (en) 1986-02-28
ES523415A0 (es) 1984-10-01
DE3379654D1 (en) 1989-05-24
EP0085959B1 (en) 1989-04-19
PL245845A1 (en) 1985-01-30
SI8310221A8 (en) 1995-10-31
KR840003628A (ko) 1984-09-15
IL67829A (en) 1988-06-30
NO162556C (no) 1990-01-17
IE54600B1 (en) 1989-12-06
HU189223B (en) 1986-06-30
NO874330D0 (no) 1987-10-16
ES8500235A1 (es) 1984-10-01
KR870001916B1 (ko) 1987-10-22
IL78419A0 (en) 1986-08-31
FI82450B (fi) 1990-11-30
KR870001915B1 (ko) 1987-10-22
ES8500234A1 (es) 1984-10-01
PL245843A1 (en) 1985-01-30
KR870001917B1 (ko) 1987-10-22
BG42185A3 (en) 1987-10-15
CA1249830A (en) 1989-02-07
CY1627A (en) 1992-07-10
DD209446A5 (de) 1984-05-09
PL140810B1 (en) 1987-05-30
JPH01301661A (ja) 1989-12-05
ES519491A0 (es) 1984-04-01
BG42005A3 (en) 1987-09-15
BG41822A3 (en) 1987-08-14
IE830213L (en) 1983-08-04
BG42004A3 (en) 1987-09-15
SU1301312A3 (ru) 1987-03-30
PL141639B1 (en) 1987-08-31
NO874330L (no) 1983-08-05
ES523417A0 (es) 1984-10-01
NL930057I1 (nl) 1993-09-01
NO172341C (no) 1993-07-07
ATE42282T1 (de) 1989-05-15
DK43683A (da) 1983-08-05
MC1498A1 (fr) 1983-11-17
NO830368L (no) 1983-08-05
PT76192A (en) 1983-03-01
BG42003A3 (en) 1987-09-15
CA1275102A (en) 1990-10-09
PL245842A1 (en) 1985-01-30
EP0249950B1 (en) 1991-06-19
JPH0468B2 (en:Method) 1992-01-06
ES523418A0 (es) 1984-10-01
PL245841A1 (en) 1985-01-30
FI82450C (fi) 1991-03-11
IL78419A (en) 1989-01-31
EP0249950A1 (en) 1987-12-23
FI830380L (fi) 1983-08-05
ES523414A0 (es) 1984-10-01
GB8302971D0 (en) 1983-03-09
CA1275102C (en:Method) 1990-10-09
ES8403872A1 (es) 1984-04-01
JPS6479153A (en) 1989-03-24
FI830380A0 (fi) 1983-02-03
GB2114565A (en) 1983-08-24
ES8500233A1 (es) 1984-10-01
PL240412A1 (en) 1985-01-30
PH21348A (en) 1987-10-13
IL67829A0 (en) 1983-06-15
NL930057I2 (nl) 1994-02-16
DE3382321D1 (de) 1991-07-25
PL140809B1 (en) 1987-05-30
GR77407B (en:Method) 1984-09-13
ES8500231A1 (es) 1984-10-01
KR870001927B1 (ko) 1987-10-22
DK164662C (da) 1992-12-14
UY23404A1 (es) 1992-10-19
AU555083B2 (en) 1986-09-11
YU44821B (en) 1991-02-28
CS235306B2 (en) 1985-05-15
PT76192B (en) 1986-01-24
PL245844A1 (en) 1985-01-30
EP0085959A2 (en) 1983-08-17
ES523416A0 (es) 1984-10-01
GB2114565B (en) 1985-06-26
DK164662B (da) 1992-07-27
NO172341B (no) 1993-03-29
EP0085959A3 (en) 1984-07-18
ES8500232A1 (es) 1984-10-01
DK43683D0 (da) 1983-02-03
PL140811B1 (en) 1987-05-30
ATE64596T1 (de) 1991-07-15
KR880001466B1 (ko) 1988-08-11
SG106091G (en) 1992-03-20
NO162556B (no) 1989-10-09
KR870001918B1 (ko) 1987-10-22

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Legal Events

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)