GR77407B - - Google Patents

Info

Publication number
GR77407B
GR77407B GR70400A GR830170400A GR77407B GR 77407 B GR77407 B GR 77407B GR 70400 A GR70400 A GR 70400A GR 830170400 A GR830170400 A GR 830170400A GR 77407 B GR77407 B GR 77407B
Authority
GR
Greece
Prior art keywords
hydrogen
compounds
nitrogen
symptomatic treatment
allergic conditions
Prior art date
Application number
GR70400A
Other languages
English (en)
Inventor
G G Coker
J W Addison Findlay
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of GR77407B publication Critical patent/GR77407B/el

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
GR70400A 1982-02-04 1983-02-03 GR77407B (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8203261 1982-02-04
GB8229705 1982-10-18

Publications (1)

Publication Number Publication Date
GR77407B true GR77407B (el) 1984-09-13

Family

ID=26281898

Family Applications (1)

Application Number Title Priority Date Filing Date
GR70400A GR77407B (el) 1982-02-04 1983-02-03

Country Status (32)

Country Link
EP (2) EP0249950B1 (el)
JP (2) JPS6479153A (el)
KR (6) KR880001466B1 (el)
AT (2) ATE64596T1 (el)
AU (1) AU555083B2 (el)
BG (6) BG42005A3 (el)
CA (2) CA1249830A (el)
CS (1) CS235306B2 (el)
CY (1) CY1627A (el)
DD (1) DD209446A5 (el)
DE (2) DE3382321D1 (el)
DK (1) DK164662C (el)
ES (6) ES8403872A1 (el)
FI (1) FI82450C (el)
GB (1) GB2114565B (el)
GR (1) GR77407B (el)
HK (1) HK25892A (el)
HU (1) HU189223B (el)
IE (1) IE54600B1 (el)
IL (3) IL67829A (el)
MC (1) MC1498A1 (el)
NL (1) NL930057I2 (el)
NO (2) NO162556C (el)
NZ (1) NZ203171A (el)
PH (1) PH21348A (el)
PL (6) PL140708B1 (el)
PT (1) PT76192B (el)
SG (1) SG106091G (el)
SI (1) SI8310221A8 (el)
SU (1) SU1301312A3 (el)
UY (1) UY23404A1 (el)
YU (1) YU44821B (el)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501893A (en) * 1982-02-04 1985-02-26 Findlay John W A 3-{6-[3-Pyrrolidino-1-(4-tolyl)prop-1-enyl]-2-pyridyl}acrylic acid and pharmaceutically acceptable salts thereof
US4610995A (en) * 1984-07-27 1986-09-09 Coker Geoffrey G Certain 1,1-diaryl-propenyl-3-(1-pyrrolidino-2-carboxylic acids, derivatives thereof and their anti-histaminic properties
LU86387A1 (fr) * 1986-04-04 1987-12-07 Oreal Composes aromatiques,leur procede de preparation et leur utilisation en medicine humaine et veterinaire et en cosmetique
GB8707416D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
DE3711866A1 (de) * 1987-04-08 1988-10-27 Hoechst Ag Synthese von peptidamiden mittels festphasenmethode unter verwendung von saeurelabilen ankergruppen
GB8914040D0 (en) * 1989-06-19 1989-08-09 Wellcome Found Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
GB8914060D0 (en) * 1989-06-19 1989-08-09 Wellcome Found Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
AU650421B2 (en) * 1989-06-19 1994-06-23 Wellcome Foundation Limited, The Medicaments useful in cancer therapy and having antihistaminic properties
FR2711651B1 (fr) * 1993-10-28 1995-12-22 Adir Nouveaux analogues cyclisés de métabolites d'acides gras, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
US5420866A (en) * 1994-03-29 1995-05-30 Scientific-Atlanta, Inc. Methods for providing conditional access information to decoders in a packet-based multiplexed communications system
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
EP0842175A1 (en) * 1995-08-05 1998-05-20 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives
IT1277597B1 (it) * 1995-09-15 1997-11-11 Smithkline Beecham Spa Derivati di diarilalchenilammina
CN101838235B (zh) * 2009-06-12 2013-08-07 重庆华邦制药有限公司 3-苯基-3＇-吡啶基丙烯胺类化合物及其合成方法
WO2012038521A1 (en) * 2010-09-23 2012-03-29 Syngenta Participations Ag Novel microbiocides
CN104254589B (zh) 2012-04-23 2016-06-15 沙特基础工业公司 基于太阳能的连续方法和用于通过相应的烷烃脱氢生产烯烃的反应器系统

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2567245A (en) * 1948-05-10 1951-09-11 Schering Corp Aryl-(2-pyridyl)-amino alkanes and their production
DE1227464B (de) * 1951-09-10 1966-10-27 Wellcome Found Verfahren zur Herstellung der trans-Form des neuen 1-(4'-Methylphenyl)-1-(2''-pyridyl)-3-pyrrolidinopropens-(1)
FR1228801A (fr) * 1954-05-03 1960-09-02 Farbwerke Hoechst Ag Vomals Me Procédé de préparation de composés tertio-amino carboxyliques et des composés tertio-amino cétoniques correspondants
FR2197583B1 (el) * 1972-09-07 1975-10-17 Rhone Poulenc Ind

Also Published As

Publication number Publication date
ES519491A0 (es) 1984-04-01
SU1301312A3 (ru) 1987-03-30
PL140708B1 (en) 1987-05-30
JPH0468B2 (el) 1992-01-06
JPS6479153A (en) 1989-03-24
AU555083B2 (en) 1986-09-11
PL240412A1 (en) 1985-01-30
YU44821B (en) 1991-02-28
ES523416A0 (es) 1984-10-01
GB2114565B (en) 1985-06-26
EP0249950A1 (en) 1987-12-23
PH21348A (en) 1987-10-13
IL78419A0 (en) 1986-08-31
DK164662B (da) 1992-07-27
PL245842A1 (en) 1985-01-30
IL67829A0 (en) 1983-06-15
ATE42282T1 (de) 1989-05-15
ES523418A0 (es) 1984-10-01
DK43683D0 (da) 1983-02-03
YU22183A (en) 1986-02-28
ES8500231A1 (es) 1984-10-01
SG106091G (en) 1992-03-20
EP0085959A3 (en) 1984-07-18
SI8310221A8 (en) 1995-10-31
CS235306B2 (en) 1985-05-15
KR870001927B1 (ko) 1987-10-22
KR870001915B1 (ko) 1987-10-22
PL141639B1 (en) 1987-08-31
DD209446A5 (de) 1984-05-09
EP0249950B1 (en) 1991-06-19
ES8403872A1 (es) 1984-04-01
BG41822A3 (en) 1987-08-14
NO874330D0 (no) 1987-10-16
NO172341B (no) 1993-03-29
JPH01301661A (ja) 1989-12-05
ATE64596T1 (de) 1991-07-15
PL140809B1 (en) 1987-05-30
PL245843A1 (en) 1985-01-30
PL245845A1 (en) 1985-01-30
FI82450C (fi) 1991-03-11
UY23404A1 (es) 1992-10-19
NO874330L (no) 1983-08-05
NO172341C (no) 1993-07-07
NO830368L (no) 1983-08-05
KR870001916B1 (ko) 1987-10-22
HU189223B (en) 1986-06-30
DK164662C (da) 1992-12-14
ES8500233A1 (es) 1984-10-01
NZ203171A (en) 1986-12-05
PT76192A (en) 1983-03-01
ES8500234A1 (es) 1984-10-01
FI830380A0 (fi) 1983-02-03
BG41821A3 (en) 1987-08-14
IE830213L (en) 1983-08-04
MC1498A1 (fr) 1983-11-17
PL245844A1 (en) 1985-01-30
KR870001918B1 (ko) 1987-10-22
CA1275102A (en) 1990-10-09
HK25892A (en) 1992-04-16
PL140810B1 (en) 1987-05-30
NL930057I2 (nl) 1994-02-16
PL245841A1 (en) 1985-01-30
CY1627A (en) 1992-07-10
NL930057I1 (nl) 1993-09-01
EP0085959A2 (en) 1983-08-17
CA1275102C (el) 1990-10-09
BG42005A3 (en) 1987-09-15
KR880001466B1 (ko) 1988-08-11
JPH0251897B2 (el) 1990-11-08
FI830380L (fi) 1983-08-05
DK43683A (da) 1983-08-05
GB2114565A (en) 1983-08-24
CA1249830A (en) 1989-02-07
IE54600B1 (en) 1989-12-06
KR840003628A (ko) 1984-09-15
DE3382321D1 (de) 1991-07-25
BG42185A3 (en) 1987-10-15
GB8302971D0 (en) 1983-03-09
KR870001917B1 (ko) 1987-10-22
PL140812B1 (en) 1987-05-30
ES8500232A1 (es) 1984-10-01
EP0085959B1 (en) 1989-04-19
PT76192B (en) 1986-01-24
ES8500235A1 (es) 1984-10-01
IL67829A (en) 1988-06-30
FI82450B (fi) 1990-11-30
NO162556B (no) 1989-10-09
ES523414A0 (es) 1984-10-01
DE3379654D1 (en) 1989-05-24
ES523415A0 (es) 1984-10-01
IL78419A (en) 1989-01-31
NO162556C (no) 1990-01-17
PL140811B1 (en) 1987-05-30
BG42003A3 (en) 1987-09-15
ES523417A0 (es) 1984-10-01
AU1098283A (en) 1983-08-11
BG42004A3 (en) 1987-09-15

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