HK1246232A1 - 用於治疗非酒精性脂肪肝病的acc抑制剂组合治疗 - Google Patents

用於治疗非酒精性脂肪肝病的acc抑制剂组合治疗 Download PDF

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Publication number
HK1246232A1
HK1246232A1 HK18105783.0A HK18105783A HK1246232A1 HK 1246232 A1 HK1246232 A1 HK 1246232A1 HK 18105783 A HK18105783 A HK 18105783A HK 1246232 A1 HK1246232 A1 HK 1246232A1
Authority
HK
Hong Kong
Prior art keywords
liver disease
fatty liver
alcoholic fatty
treatment
combination therapy
Prior art date
Application number
HK18105783.0A
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English (en)
Chinese (zh)
Inventor
Geraldine C. Harriman
Rosana Kapeller-Libermann
William F. Westlin
H. James Harwood
Original Assignee
Gilead Apollo, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Gilead Apollo, Llc filed Critical Gilead Apollo, Llc
Publication of HK1246232A1 publication Critical patent/HK1246232A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18105783.0A 2015-01-09 2016-01-08 用於治疗非酒精性脂肪肝病的acc抑制剂组合治疗 HK1246232A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562101726P 2015-01-09 2015-01-09
US62/101,726 2015-01-09
PCT/US2016/012673 WO2016112305A1 (en) 2015-01-09 2016-01-08 Acc inhibitor combination therapy for the treatment of non-alcoholic fatty liver disease

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
HK42020011371.0A Division HK40021469A (en) 2015-01-09 2018-05-04 Acc inhibitor combination therapy for the treatment of non-alcoholic fatty liver disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
HK42020011371.0A Addition HK40021469A (en) 2015-01-09 2018-05-04 Acc inhibitor combination therapy for the treatment of non-alcoholic fatty liver disease

Publications (1)

Publication Number Publication Date
HK1246232A1 true HK1246232A1 (zh) 2018-09-07

Family

ID=56356482

Family Applications (2)

Application Number Title Priority Date Filing Date
HK18105783.0A HK1246232A1 (zh) 2015-01-09 2016-01-08 用於治疗非酒精性脂肪肝病的acc抑制剂组合治疗
HK18102859.6A HK1243369A1 (zh) 2015-01-09 2016-01-08 用於治疗非酒精性脂肪肝病的acc抑制剂组合治疗

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK18102859.6A HK1243369A1 (zh) 2015-01-09 2016-01-08 用於治疗非酒精性脂肪肝病的acc抑制剂组合治疗

Country Status (13)

Country Link
US (2) US20180021341A1 (https=)
EP (2) EP3597271A1 (https=)
JP (2) JP2018501276A (https=)
KR (1) KR20170102299A (https=)
CN (1) CN107106873A (https=)
AU (1) AU2016205138A1 (https=)
BR (1) BR112017014341A2 (https=)
CA (1) CA2972919A1 (https=)
EA (2) EA201892625A1 (https=)
HK (2) HK1246232A1 (https=)
MX (1) MX2017008844A (https=)
SG (1) SG11201705361PA (https=)
WO (1) WO2016112305A1 (https=)

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Publication number Publication date
JP2018501276A (ja) 2018-01-18
JP2020109130A (ja) 2020-07-16
EA201892625A1 (ru) 2019-07-31
EP3242722A4 (en) 2018-07-11
MX2017008844A (es) 2018-03-14
AU2016205138A1 (en) 2017-07-13
US20180021341A1 (en) 2018-01-25
EP3242722A1 (en) 2017-11-15
WO2016112305A1 (en) 2016-07-14
EA201791258A1 (ru) 2017-12-29
US20190381045A1 (en) 2019-12-19
EP3597271A1 (en) 2020-01-22
HK1243369A1 (zh) 2018-07-13
KR20170102299A (ko) 2017-09-08
CA2972919A1 (en) 2016-07-14
BR112017014341A2 (pt) 2018-03-27
CN107106873A (zh) 2017-08-29
SG11201705361PA (en) 2017-08-30

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