HK1224140A1 - 转录因子抑制剂及其用途 - Google Patents
转录因子抑制剂及其用途 Download PDFInfo
- Publication number
- HK1224140A1 HK1224140A1 HK16112643.8A HK16112643A HK1224140A1 HK 1224140 A1 HK1224140 A1 HK 1224140A1 HK 16112643 A HK16112643 A HK 16112643A HK 1224140 A1 HK1224140 A1 HK 1224140A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- substituted
- unsubstituted
- compound
- formula
- pharmaceutically acceptable
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361858521P | 2013-07-25 | 2013-07-25 | |
| US61/858,521 | 2013-07-25 | ||
| PCT/US2014/048230 WO2015013635A2 (en) | 2013-07-25 | 2014-07-25 | Inhibitors of transcription factors and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1224140A1 true HK1224140A1 (zh) | 2017-08-18 |
Family
ID=52393987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16112643.8A HK1224140A1 (zh) | 2013-07-25 | 2014-07-25 | 转录因子抑制剂及其用途 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9975896B2 (https=) |
| EP (1) | EP3024327B1 (https=) |
| JP (1) | JP2016531113A (https=) |
| KR (1) | KR20160034379A (https=) |
| CN (1) | CN105611835A (https=) |
| AU (1) | AU2014292888B2 (https=) |
| BR (1) | BR112016001457A2 (https=) |
| CA (1) | CA2918910A1 (https=) |
| HK (1) | HK1224140A1 (https=) |
| MX (1) | MX2016001037A (https=) |
| RU (1) | RU2016105108A (https=) |
| WO (1) | WO2015013635A2 (https=) |
Families Citing this family (91)
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- 2014-07-25 CA CA2918910A patent/CA2918910A1/en not_active Abandoned
- 2014-07-25 JP JP2016530079A patent/JP2016531113A/ja active Pending
- 2014-07-25 EP EP14828728.7A patent/EP3024327B1/en active Active
- 2014-07-25 CN CN201480052916.XA patent/CN105611835A/zh active Pending
- 2014-07-25 RU RU2016105108A patent/RU2016105108A/ru not_active Application Discontinuation
- 2014-07-25 WO PCT/US2014/048230 patent/WO2015013635A2/en not_active Ceased
- 2014-07-25 HK HK16112643.8A patent/HK1224140A1/zh unknown
- 2014-07-25 BR BR112016001457A patent/BR112016001457A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP3024327B1 (en) | 2019-09-04 |
| RU2016105108A (ru) | 2017-08-30 |
| CN105611835A (zh) | 2016-05-25 |
| MX2016001037A (es) | 2016-11-10 |
| WO2015013635A2 (en) | 2015-01-29 |
| CA2918910A1 (en) | 2015-01-29 |
| EP3024327A2 (en) | 2016-06-01 |
| RU2016105108A3 (https=) | 2018-05-25 |
| AU2014292888B2 (en) | 2018-03-22 |
| JP2016531113A (ja) | 2016-10-06 |
| WO2015013635A3 (en) | 2015-04-02 |
| AU2014292888A1 (en) | 2016-02-11 |
| BR112016001457A2 (pt) | 2017-08-29 |
| US20160168154A1 (en) | 2016-06-16 |
| US9975896B2 (en) | 2018-05-22 |
| EP3024327A4 (en) | 2017-03-01 |
| KR20160034379A (ko) | 2016-03-29 |
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