HK1221978A1 - Tmprss6 irna组合物及其使用方法 - Google Patents

Tmprss6 irna组合物及其使用方法 Download PDF

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Publication number
HK1221978A1
HK1221978A1 HK16110216.9A HK16110216A HK1221978A1 HK 1221978 A1 HK1221978 A1 HK 1221978A1 HK 16110216 A HK16110216 A HK 16110216A HK 1221978 A1 HK1221978 A1 HK 1221978A1
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Hong Kong
Prior art keywords
nucleotides
sense strand
antisense strand
methods
strand
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HK16110216.9A
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English (en)
Chinese (zh)
Inventor
James Butler
Brian Bettencourt
Kallanthottathil G. Rajeev
Martin Maier
Klaus CHARISSE
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Alnylam Pharmaceuticals, Inc.
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Application filed by Alnylam Pharmaceuticals, Inc. filed Critical Alnylam Pharmaceuticals, Inc.
Publication of HK1221978A1 publication Critical patent/HK1221978A1/zh

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
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HK16110216.9A 2013-05-22 2014-05-22 Tmprss6 irna组合物及其使用方法 HK1221978A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361826178P 2013-05-22 2013-05-22
US61/826,178 2013-05-22
US201361912988P 2013-12-06 2013-12-06
US61/912,988 2013-12-06
PCT/US2014/039149 WO2014190157A1 (en) 2013-05-22 2014-05-22 Tmprss6 compositions and methods of use thereof

Publications (1)

Publication Number Publication Date
HK1221978A1 true HK1221978A1 (zh) 2017-06-16

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Application Number Title Priority Date Filing Date
HK16110216.9A HK1221978A1 (zh) 2013-05-22 2014-05-22 Tmprss6 irna组合物及其使用方法

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Country Link
US (6) US9783806B2 (enExample)
EP (3) EP2999786A1 (enExample)
JP (5) JP2016520593A (enExample)
KR (3) KR102365809B1 (enExample)
CN (2) CN110317810A (enExample)
AP (1) AP2015008862A0 (enExample)
AU (4) AU2014268529C1 (enExample)
BR (1) BR112015029276B1 (enExample)
CA (3) CA3279634A1 (enExample)
CL (2) CL2015003440A1 (enExample)
EA (1) EA201592225A1 (enExample)
HK (1) HK1221978A1 (enExample)
IL (6) IL285780B (enExample)
MY (1) MY181888A (enExample)
RU (1) RU2015154738A (enExample)
SG (2) SG10202103166XA (enExample)
TW (3) TW202605150A (enExample)
UY (1) UY35583A (enExample)
WO (1) WO2014190157A1 (enExample)
ZA (1) ZA202110854B (enExample)

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KR102104401B1 (ko) 2011-03-29 2020-04-27 알닐람 파마슈티칼스 인코포레이티드 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법
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WO2015099122A1 (ja) 2013-12-26 2015-07-02 学校法人東京医科大学 遺伝子発現制御のための人工ミミックｍｉＲＮＡおよびその用途
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