TWI727917B - ＴＭＰＲＳＳ６ｉＲＮＡ 組成物及其使用方法 - Google Patents

ＴＭＰＲＳＳ６ｉＲＮＡ 組成物及其使用方法 Download PDF

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TWI727917B
TWI727917B TW103117873A TW103117873A TWI727917B TW I727917 B TWI727917 B TW I727917B TW 103117873 A TW103117873 A TW 103117873A TW 103117873 A TW103117873 A TW 103117873A TW I727917 B TWI727917 B TW I727917B
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nucleotides
rnai agent
double
strand
tmprss6
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TW103117873A
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Chinese (zh)
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TW201536916A (zh
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吉姆 巴特勒
布萊恩 貝當古
卡蘭多達堤爾Ｇ 拉杰夫
馬丁 梅爾
克勞斯 查里斯
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美商阿尼拉製藥公司
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    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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TW103117873A 2013-05-22 2014-05-22 ＴＭＰＲＳＳ６ｉＲＮＡ 組成物及其使用方法 TWI727917B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361826178P 2013-05-22 2013-05-22
US61/826,178 2013-05-22
US201361912988P 2013-12-06 2013-12-06
US61/912,988 2013-12-06

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TW201536916A TW201536916A (zh) 2015-10-01
TWI727917B true TWI727917B (zh) 2021-05-21

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Application Number Title Priority Date Filing Date
TW103117873A TWI727917B (zh) 2013-05-22 2014-05-22 ＴＭＰＲＳＳ６ｉＲＮＡ 組成物及其使用方法
TW110108158A TWI853153B (zh) 2013-05-22 2014-05-22 TMPRSS6 iRNA 組成物及其使用方法
TW112125688A TW202342750A (zh) 2013-05-22 2014-05-22 ＴＭＰＲＳＳ６ ｉＲＮＡ組成物及其使用方法

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TW110108158A TWI853153B (zh) 2013-05-22 2014-05-22 TMPRSS6 iRNA 組成物及其使用方法
TW112125688A TW202342750A (zh) 2013-05-22 2014-05-22 ＴＭＰＲＳＳ６ ｉＲＮＡ組成物及其使用方法

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US (6) US9783806B2 (enExample)
EP (3) EP3587578A1 (enExample)
JP (5) JP2016520593A (enExample)
KR (3) KR102234623B1 (enExample)
CN (2) CN110317810A (enExample)
AP (1) AP2015008862A0 (enExample)
AU (4) AU2014268529C1 (enExample)
BR (1) BR112015029276B1 (enExample)
CA (2) CA3178370A1 (enExample)
CL (2) CL2015003440A1 (enExample)
EA (1) EA201592225A1 (enExample)
HK (1) HK1221978A1 (enExample)
IL (6) IL313320B1 (enExample)
MY (1) MY181888A (enExample)
RU (1) RU2015154738A (enExample)
SG (2) SG10202103166XA (enExample)
TW (3) TWI727917B (enExample)
UY (1) UY35583A (enExample)
WO (1) WO2014190157A1 (enExample)
ZA (1) ZA202110854B (enExample)

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EP2691121A4 (en) 2011-03-29 2015-08-26 Alnylam Pharmaceuticals Inc COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TMPRSS6 GENE
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WO2014081980A2 (en) * 2012-11-21 2014-05-30 The Trustees Of Columbia University In The City Of New York Mutant ngal proteins and uses thereof
TWI727917B (zh) 2013-05-22 2021-05-21 美商阿尼拉製藥公司 ＴＭＰＲＳＳ６ｉＲＮＡ 組成物及其使用方法
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CN110799647A (zh) 2017-06-23 2020-02-14 马萨诸塞大学 双尾自递送sirna及相关的方法
AU2019239971B2 (en) 2018-03-21 2025-09-11 Regeneron Pharmaceuticals, Inc. 17beta-hydroxysteroid dehydrogenase type 13 (HSD17b13) iRNA compositions and methods of use thereof
KR102857148B1 (ko) * 2018-04-05 2025-09-11 사일런스 테라퓨틱스 게엠베하 안티센스 가닥의 5' 단부에 비닐포스포네이트를 갖는 siRNA
TWI851574B (zh) * 2018-05-14 2024-08-11 美商阿尼拉製藥公司 血管收縮素原（ＡＧＴ）ｉＲＮＡ組成物及其使用方法
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