HK1221251A1 - 鋅指核酸酶介導的同源重組 - Google Patents

鋅指核酸酶介導的同源重組 Download PDF

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Publication number
HK1221251A1
HK1221251A1 HK16109210.7A HK16109210A HK1221251A1 HK 1221251 A1 HK1221251 A1 HK 1221251A1 HK 16109210 A HK16109210 A HK 16109210A HK 1221251 A1 HK1221251 A1 HK 1221251A1
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Hong Kong
Prior art keywords
sequence
sequences
dna
cleavage
target
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HK16109210.7A
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English (en)
Chinese (zh)
Inventor
蔡其華
蔡其华
杰弗里‧米勒
威廉‧
威廉‧M‧安利
‧安利
罗比‧J‧加里森
羅比‧
约瑟夫‧F‧皮托利诺
‧加里森
贝丝‧C‧鲁宾-威尔逊
約瑟夫‧
莉萨‧L‧舒伦伯格
‧皮托利諾
安德鲁‧F‧沃登
貝絲‧
‧魯賓-威爾遜
莉薩‧
‧舒倫伯格
安德魯‧
‧沃登
Original Assignee
陶氏益农公司
桑格摩生物科学股份有限公司
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Application filed by 陶氏益农公司, 桑格摩生物科学股份有限公司 filed Critical 陶氏益农公司
Publication of HK1221251A1 publication Critical patent/HK1221251A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A01H1/06—Processes for producing mutations, e.g. treatment with chemicals or with radiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/14—Plant cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
HK16109210.7A 2006-08-11 2010-03-05 鋅指核酸酶介導的同源重組 HK1221251A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83714706P 2006-08-11 2006-08-11
US60/837,147 2006-08-11

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
HK10102344.7A Addition HK1134320B (en) 2006-08-11 2007-08-09 Zinc finger nuclease-mediated homologous recombination

Related Child Applications (1)

Application Number Title Priority Date Filing Date
HK10102344.7A Division HK1134320B (en) 2006-08-11 2007-08-09 Zinc finger nuclease-mediated homologous recombination

Publications (1)

Publication Number Publication Date
HK1221251A1 true HK1221251A1 (zh) 2017-05-26

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HK16109210.7A HK1221251A1 (zh) 2006-08-11 2010-03-05 鋅指核酸酶介導的同源重組

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US (2) US9428756B2 (enExample)
EP (2) EP2049663B1 (enExample)
JP (4) JP2010500029A (enExample)
KR (1) KR101439568B1 (enExample)
CN (2) CN101528924B (enExample)
AR (3) AR062336A1 (enExample)
AU (1) AU2007284748B2 (enExample)
BR (1) BRPI0716427A2 (enExample)
CA (1) CA2660485C (enExample)
DK (1) DK2049663T3 (enExample)
ES (1) ES2532002T3 (enExample)
HK (1) HK1221251A1 (enExample)
IL (1) IL196942A (enExample)
PL (1) PL2049663T3 (enExample)
SI (1) SI2049663T1 (enExample)
TW (1) TWI424061B (enExample)
UA (1) UA106193C2 (enExample)
WO (1) WO2008021207A2 (enExample)
ZA (1) ZA200900787B (enExample)

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