HK1220258A1 - 光墊顯微鏡 - Google Patents
光墊顯微鏡Info
- Publication number
- HK1220258A1 HK1220258A1 HK16108281.3A HK16108281A HK1220258A1 HK 1220258 A1 HK1220258 A1 HK 1220258A1 HK 16108281 A HK16108281 A HK 16108281A HK 1220258 A1 HK1220258 A1 HK 1220258A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- light
- pad microscope
- microscope
- pad
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/06—Means for illuminating specimens
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/365—Control or image processing arrangements for digital or video microscopes
- G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
- Multimedia (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Microscoopes, Condenser (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161442616P | 2011-02-14 | 2011-02-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1220258A1 true HK1220258A1 (zh) | 2017-04-28 |
Family
ID=45768190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16108281.3A HK1220258A1 (zh) | 2011-02-14 | 2016-07-14 | 光墊顯微鏡 |
Country Status (6)
Country | Link |
---|---|
US (1) | US10908403B2 (zh) |
EP (2) | EP2985649A1 (zh) |
JP (4) | JP6174493B2 (zh) |
CN (3) | CN105116529B (zh) |
HK (1) | HK1220258A1 (zh) |
WO (1) | WO2012110488A2 (zh) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
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US20130182081A1 (en) * | 2012-01-12 | 2013-07-18 | Gary Greenberg | Real-Time Stereo 3D Digital/Video Imaging in a Light Microscope Using a Single Lens and a Single Camera |
JP6086366B2 (ja) * | 2013-04-05 | 2017-03-01 | 国立研究開発法人理化学研究所 | 顕微鏡、焦準器具、流体保持器具、及び光学ユニット |
EP2801855B1 (en) * | 2013-05-10 | 2019-07-17 | European Molecular Biology Laboratory | A microscope module for imaging a sample |
DE102013208872B4 (de) | 2013-05-14 | 2023-08-17 | Carl Zeiss Microscopy Gmbh | Verfahren zur Erzeugung eines Bildes einer Probe |
DE102013107297A1 (de) * | 2013-07-10 | 2015-01-15 | Carl Zeiss Microscopy Gmbh | Anordnung zur Lichtblattmikroskopie |
DE202013012338U1 (de) | 2013-07-10 | 2016-04-29 | Carl Zeiss Microscopy Gmbh | Anordnung zur Lichtblattmikroskopie |
DE102013227103B4 (de) * | 2013-09-03 | 2018-05-30 | Leica Microsystems Cms Gmbh | Mikroskop mit einer akustooptischen Vorrichtung |
DE102013110093B3 (de) * | 2013-09-13 | 2015-01-22 | Johann Wolfgang Goethe-Universität | Küvette für eine inverse Fluoreszenz-Untersuchung |
US10539772B2 (en) * | 2013-10-09 | 2020-01-21 | Howard Hughes Medical Institute | Multiview light-sheet microscopy |
DE102013112596B4 (de) | 2013-11-15 | 2023-12-28 | Carl Zeiss Microscopy Gmbh | Anordnung zur Lichtblattmikroskopie |
DE102013112595B4 (de) | 2013-11-15 | 2024-08-01 | Carl Zeiss Microscopy Gmbh | Anordnung zur Lichtblattmikroskopie |
DE102013112600A1 (de) | 2013-11-15 | 2015-05-21 | Carl Zeiss Microscopy Gmbh | Optisches Übertragungssystem und Mikroskop mit einem solchen Übertragungssystem |
GB2520541A (en) * | 2013-11-25 | 2015-05-27 | European Molecular Biology Lab Embl | Optical arrangement for imaging a sample |
DE102014204994A1 (de) * | 2014-03-18 | 2015-09-24 | Carl Zeiss Microscopy Gmbh | Verfahren zur Fluoreszenzmikroskopie einer Probe |
CN103885166A (zh) * | 2014-03-28 | 2014-06-25 | 天津大学 | 基于布拉格衍射晶体的超高分辨非线性激发荧光显微系统 |
EP2930549B1 (en) * | 2014-04-08 | 2023-05-03 | European Molecular Biology Laboratory | An optical arrangement and method for imaging a sample |
DE102014104977B4 (de) | 2014-04-08 | 2023-11-30 | Carl Zeiss Microscopy Gmbh | Anordnung zur Lichtblattmikroskopie sowie Mikroskopobjektiv für die Lichtblattmikroskopie |
EP3198326A4 (en) * | 2014-09-24 | 2018-05-23 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Resolution enhancement for light sheet microscopy systems and methods |
EP3213137A4 (en) * | 2014-10-29 | 2018-05-02 | Lumencor, Inc. | Integrated fluorescence scanning system |
JP6552043B2 (ja) * | 2014-11-04 | 2019-07-31 | オリンパス株式会社 | シート照明顕微鏡 |
US10007100B2 (en) * | 2014-11-04 | 2018-06-26 | Olympus Corporation | Light sheet illumination microscope and light sheet illumination method |
DE102014119255A1 (de) | 2014-12-19 | 2016-06-23 | Carl Zeiss Microscopy Gmbh | Verfahren zur lichtblattmikroskopischen Untersuchung einer Probe |
FR3031196B1 (fr) * | 2014-12-29 | 2017-01-13 | Karla Balaa | Dispositif pour realiser de la microscopie a feuille de lumiere |
DE102015103802A1 (de) | 2015-03-16 | 2016-09-22 | Carl Zeiss Microscopy Gmbh | Verfahren und Anordnung zur lichtblattmikroskopischen Untersuchung einer Probe |
JP6417262B2 (ja) * | 2015-04-15 | 2018-11-07 | オリンパス株式会社 | シート照明顕微鏡 |
DE102015209758A1 (de) | 2015-05-28 | 2016-12-01 | Carl Zeiss Microscopy Gmbh | Anordnung und Verfahren zur Strahlformung und zur Lichtblattmikroskopie |
DE102015209756A1 (de) | 2015-05-28 | 2016-12-01 | Carl Zeiss Microscopy Gmbh | Anordnung und Verfahren zur Lichtblattmikroskopie |
CN105138820B (zh) * | 2015-07-24 | 2019-01-15 | 天津大学 | 一种适用于多模光纤下的表面等离子共振信号共振波长的计算方法 |
KR101817122B1 (ko) * | 2015-12-14 | 2018-01-10 | 경희대학교 산학협력단 | 분자 통신 시스템, 분자 통신 방법, 분자 송신기 및 분자 수신기 |
DE102016204653B4 (de) * | 2016-03-21 | 2022-12-22 | Carl Zeiss Microscopy Gmbh | Die Erfindung betrifft ein Lichtblattmikroskop sowie ein Verfahren zum Betreiben eines Lichtblattmikroskops |
LU93022B1 (de) * | 2016-04-08 | 2017-11-08 | Leica Microsystems | Verfahren und Mikroskop zum Untersuchen einer Probe |
DE102016108384B3 (de) * | 2016-05-04 | 2017-11-09 | Leica Microsystems Cms Gmbh | Vorrichtung und Verfahren zur lichtblattartigen Beleuchtung einer Probe |
JP2017203822A (ja) * | 2016-05-09 | 2017-11-16 | オリンパス株式会社 | 照明設定方法、シート照明顕微鏡装置、及びプログラム |
AU2017281533B2 (en) | 2016-06-24 | 2019-06-27 | Howard Hughes Medical Institute | Automated adjustment of light sheet geometry in a microscope |
DE102016212019A1 (de) | 2016-07-01 | 2018-01-04 | Carl Zeiss Microscopy Gmbh | Neigungsmessung und -korrektur des Deckglases im Strahlengang eines Mikroskops |
DE102016119268B3 (de) * | 2016-10-10 | 2017-12-21 | Leica Microsystems Cms Gmbh | Schiefebenenmikroskop |
CN111142251B (zh) * | 2016-10-26 | 2022-03-25 | 合肥百会拓知科技有限公司 | 一种具有三维成像能力的显微镜和成像方法 |
DE102016120683A1 (de) * | 2016-10-28 | 2018-05-03 | Carl Zeiss Microscopy Gmbh | Lichtblattmikroskop |
EP3538941A4 (en) | 2016-11-10 | 2020-06-17 | The Trustees of Columbia University in the City of New York | METHODS FOR FAST IMAGING OF HIGH RESOLUTION LARGE SAMPLES |
WO2018125925A1 (en) * | 2016-12-27 | 2018-07-05 | The Regents Of The University Of Michigan | Laser emission based microscope |
JP2018169502A (ja) * | 2017-03-30 | 2018-11-01 | オリンパス株式会社 | 顕微鏡装置 |
CN110799878B (zh) * | 2017-06-23 | 2022-10-14 | 莱卡微系统Cms有限责任公司 | 具有光片显微的功能单元的显微系统 |
DE102017214189A1 (de) * | 2017-08-15 | 2019-02-21 | Carl Zeiss Microscopy Gmbh | Verfahren zum Betrieb einer Mikroskopieranordnung und Mikroskopieranordnung mit einem ersten Mikroskop und mindestens einem weiteren Mikroskop |
DE102017122718A1 (de) | 2017-09-29 | 2019-04-04 | Carl Zeiss Microscopy Gmbh | Verfahren und Vorrichtung zur optischen Untersuchung einer Vielzahl mikroskopischer Proben |
JP7228917B2 (ja) * | 2018-01-02 | 2023-02-27 | キングス カレッジ ロンドン | 局在化顕微鏡法のための方法及びシステム |
IT201800003984A1 (it) * | 2018-03-27 | 2019-09-27 | Crestoptics S P A | Metodo di microscopia assistita da dispersione a super localizzazione e relativo apparato |
CN115078319A (zh) * | 2018-06-27 | 2022-09-20 | 因纽美瑞克斯公司 | 用于透明化液滴成像的光片荧光显微成像装置及检测方法 |
CN109143562B (zh) * | 2018-09-12 | 2020-12-15 | 苏州大学 | 一种基于变焦原理的可变光片照明系统 |
CN109357975B (zh) * | 2018-10-31 | 2021-05-18 | 福州大学 | 一种测量生物分子有效扩散系数的方法 |
DE102018222876A1 (de) * | 2018-12-21 | 2020-06-25 | Leica Microsystems Cms Gmbh | Mikroskop und Verfahren zur mikroskopischen Untersuchung großer Proben |
US11187659B2 (en) * | 2019-03-28 | 2021-11-30 | The Regents Of The University Of California | Systems for fluorescence light sheet microscopy of large samples in high refractive index solutions |
CN110609026B (zh) * | 2019-10-31 | 2020-11-03 | 福州大学 | 激光功率反馈控制的上转换荧光成像装置及其成像方法 |
CN112697759A (zh) * | 2020-12-10 | 2021-04-23 | 北京林业大学 | 荧光相关光谱(fcs)在植物细胞核中的应用方法 |
DE102021104871A1 (de) | 2021-03-01 | 2022-09-01 | Carl Zeiss Microscopy Gmbh | Verfahren und Vorrichtung zur lichtblattmikroskopischen Untersuchung einer Probe |
EP4301499A1 (en) | 2021-03-05 | 2024-01-10 | Enumerix, Inc. | Systems and methods for generating droplets and performing digital analyses |
CN113406046A (zh) * | 2021-05-17 | 2021-09-17 | 南方医科大学 | 一种近红外光片显微镜 |
CN117794646A (zh) | 2021-06-04 | 2024-03-29 | 伊努梅里斯公司 | 用于单细胞条形码化和测序的组合物、方法和系统 |
US11619586B2 (en) | 2021-07-08 | 2023-04-04 | X Development Llc | System for imaging and selective illumination of targets within a sample |
US11834714B2 (en) | 2021-12-20 | 2023-12-05 | Enumerix, Inc. | Detection and digital quantitation of multiple targets |
DE102022125117A1 (de) | 2022-09-29 | 2024-04-04 | Carl Zeiss Microscopy Gmbh | Lichtblattmikroskop |
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JPH09210909A (ja) | 1996-02-06 | 1997-08-15 | Mitsubishi Heavy Ind Ltd | レーザ光を用いた計測装置 |
US6833242B2 (en) | 1997-09-23 | 2004-12-21 | California Institute Of Technology | Methods for detecting and sorting polynucleotides based on size |
JPH11326616A (ja) | 1998-03-11 | 1999-11-26 | Nippon Steel Corp | ミラーおよびそれを用いた集光光学系 |
DE10235388A1 (de) * | 2002-08-02 | 2004-02-19 | Carl Zeiss Jena Gmbh | Optische Anordnung mit telezentrischem Strahlenbereich |
DE10257423A1 (de) | 2002-12-09 | 2004-06-24 | Europäisches Laboratorium für Molekularbiologie (EMBL) | Mikroskop |
JP4624695B2 (ja) | 2003-03-20 | 2011-02-02 | オリンパス株式会社 | システム顕微鏡 |
DE10319182B4 (de) * | 2003-04-29 | 2008-06-12 | Carl Zeiss Jena Gmbh | Verfahren und Anordnung zur Bestimmung der Fokusposition bei der Abbildung einer Probe |
JP4125648B2 (ja) | 2003-08-11 | 2008-07-30 | 大倉インダストリー株式会社 | ライン状光ビーム発生装置及びレーザ顕微鏡 |
DE102005000915A1 (de) * | 2005-01-06 | 2006-07-20 | Leica Microsystems Cms Gmbh | Vorrichtung zur multifokalen konfokalen mirkoskopischen Bestimmung der räumlichen Verteilung und zur multifokalen Fluktuationsanalyse von fluoreszenten Molekülen und Strukturen mit spektral flexibler Detektion |
CN1300563C (zh) | 2005-03-24 | 2007-02-14 | 华中科技大学 | 一种微型三维自扫描共焦显微镜 |
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JP2007225874A (ja) | 2006-02-23 | 2007-09-06 | Olympus Corp | 生体観察方法および生体観察装置 |
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WO2007124437A2 (en) | 2006-04-20 | 2007-11-01 | Washington University In St. Louis | Objective-coupled selective plane illumination microscopy |
EP2057496B1 (en) | 2006-08-14 | 2012-10-24 | Westover Scientific, Inc. | Solid state fluorescence light assembly and microscope |
DE102007015063B4 (de) * | 2007-03-29 | 2019-10-17 | Carl Zeiss Microscopy Gmbh | Optische Anordnung zum Erzeugen eines Lichtblattes |
DE102007045897A1 (de) * | 2007-09-26 | 2009-04-09 | Carl Zeiss Microimaging Gmbh | Verfahren zur mikroskopischen dreidimensionalen Abbildung einer Probe |
DE102007063274B8 (de) * | 2007-12-20 | 2022-12-15 | Albert-Ludwigs-Universität Freiburg | Mikroskop |
JP2009156659A (ja) | 2007-12-26 | 2009-07-16 | Olympus Corp | 測定装置及び測定方法 |
DE102008009216A1 (de) | 2008-02-13 | 2009-08-20 | Carl Zeiss Microimaging Gmbh | Vorrichtung und Verfahren zum räumlich hochauflösenden Abbilden einer Struktur einer Probe |
JP2009276544A (ja) * | 2008-05-14 | 2009-11-26 | Olympus Corp | 顕微鏡照明装置 |
WO2010014244A2 (en) * | 2008-07-30 | 2010-02-04 | The Regents Of The University Of California, San Francisco | Multidirectional selective plane illumination microscopy |
JP5131552B2 (ja) | 2008-09-16 | 2013-01-30 | 横河電機株式会社 | 顕微鏡装置 |
JP5311196B2 (ja) * | 2008-09-16 | 2013-10-09 | 横河電機株式会社 | 顕微鏡装置 |
JP5311195B2 (ja) | 2008-09-16 | 2013-10-09 | 横河電機株式会社 | 顕微鏡装置 |
US8363317B2 (en) * | 2009-06-23 | 2013-01-29 | Raytheon Canada Limited | Method and apparatus for focusing a microscope |
CN101661000B (zh) | 2009-09-18 | 2012-07-04 | 中国科学院等离子体物理研究所 | 一种基于分光镜的应用于单离子微束装置的新型离子探测系统 |
US8711211B2 (en) * | 2010-06-14 | 2014-04-29 | Howard Hughes Medical Institute | Bessel beam plane illumination microscope |
-
2012
- 2012-02-13 US US13/371,991 patent/US10908403B2/en active Active
- 2012-02-14 EP EP15178313.1A patent/EP2985649A1/en active Pending
- 2012-02-14 WO PCT/EP2012/052472 patent/WO2012110488A2/en active Application Filing
- 2012-02-14 EP EP12706003.6A patent/EP2676163B1/en active Active
- 2012-02-14 CN CN201510526165.7A patent/CN105116529B/zh active Active
- 2012-02-14 CN CN201910917415.8A patent/CN110764242A/zh active Pending
- 2012-02-14 JP JP2013552984A patent/JP6174493B2/ja active Active
- 2012-02-14 CN CN201280008835.0A patent/CN103649813A/zh active Pending
-
2016
- 2016-07-14 HK HK16108281.3A patent/HK1220258A1/zh unknown
-
2017
- 2017-04-06 JP JP2017075754A patent/JP6535359B2/ja active Active
-
2019
- 2019-05-31 JP JP2019102947A patent/JP6912516B2/ja active Active
-
2021
- 2021-07-08 JP JP2021113642A patent/JP2021184094A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2012110488A2 (en) | 2012-08-23 |
EP2985649A1 (en) | 2016-02-17 |
JP2014507014A (ja) | 2014-03-20 |
CN110764242A (zh) | 2020-02-07 |
CN103649813A (zh) | 2014-03-19 |
US10908403B2 (en) | 2021-02-02 |
CN105116529A (zh) | 2015-12-02 |
JP2021184094A (ja) | 2021-12-02 |
US20120206798A1 (en) | 2012-08-16 |
JP2019174827A (ja) | 2019-10-10 |
EP2676163B1 (en) | 2020-11-18 |
WO2012110488A3 (en) | 2012-10-11 |
JP6174493B2 (ja) | 2017-08-02 |
CN105116529B (zh) | 2019-12-13 |
EP2676163A2 (en) | 2013-12-25 |
JP2017129880A (ja) | 2017-07-27 |
JP6912516B2 (ja) | 2021-08-04 |
JP6535359B2 (ja) | 2019-06-26 |
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