HK1216708A1 - 用於鑒定生物組織的系統和方法 - Google Patents

用於鑒定生物組織的系統和方法

Info

Publication number
HK1216708A1
HK1216708A1 HK16104749.8A HK16104749A HK1216708A1 HK 1216708 A1 HK1216708 A1 HK 1216708A1 HK 16104749 A HK16104749 A HK 16104749A HK 1216708 A1 HK1216708 A1 HK 1216708A1
Authority
HK
Hong Kong
Prior art keywords
identification
biological tissues
tissues
biological
Prior art date
Application number
HK16104749.8A
Other languages
English (en)
Inventor
鄒坦．塔卡茨
Original Assignee
Micromass Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass Ltd filed Critical Micromass Ltd
Publication of HK1216708A1 publication Critical patent/HK1216708A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/623—Ion mobility spectrometry combined with mass spectrometry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165—Electrospray ionisation
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/168—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission field ionisation, e.g. corona discharge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B2010/0208—Biopsy devices with actuators, e.g. with triggered spring mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N2001/028—Sampling from a surface, swabbing, vaporising
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N2001/045—Laser ablation; Microwave vaporisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2873—Cutting or cleaving
    • G01N2001/2886—Laser cutting, e.g. tissue catapult
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
HK16104749.8A 2009-05-27 2016-04-26 用於鑒定生物組織的系統和方法 HK1216708A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18142109P 2009-05-27 2009-05-27

Publications (1)

Publication Number Publication Date
HK1216708A1 true HK1216708A1 (zh) 2016-12-02

Family

ID=42671622

Family Applications (2)

Application Number Title Priority Date Filing Date
HK16104749.8A HK1216708A1 (zh) 2009-05-27 2016-04-26 用於鑒定生物組織的系統和方法
HK16105178.5A HK1217228A1 (zh) 2009-05-27 2016-05-06 用於鑒定生物組織的系統和方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK16105178.5A HK1217228A1 (zh) 2009-05-27 2016-05-06 用於鑒定生物組織的系統和方法

Country Status (11)

Country Link
US (3) US9046448B2 (zh)
EP (2) EP2435814B1 (zh)
JP (4) JP6035145B2 (zh)
KR (2) KR101787016B1 (zh)
CN (4) CN102483369B (zh)
AU (1) AU2010252652B2 (zh)
CA (1) CA2763145C (zh)
HK (2) HK1216708A1 (zh)
MX (1) MX2011012540A (zh)
RU (1) RU2558884C2 (zh)
WO (1) WO2010136887A1 (zh)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU226837B1 (hu) 2006-05-31 2009-12-28 Semmelweis Egyetem Folyadéksugárral mûködõ deszorpciós ionizációs eljárás és eszköz
CN102483369B (zh) 2009-05-27 2015-11-25 英国质谱有限公司 用于鉴定生物组织的系统和方法
DE102010015899B4 (de) * 2010-02-04 2022-07-28 Erbe Elektromedizin Gmbh Elektrochirurgische Anordnung und elektrochirurgisches Instrument
GB201109414D0 (en) 2011-06-03 2011-07-20 Micromass Ltd Diathermy -ionisation technique
CN104254772B (zh) 2011-12-28 2018-11-16 英国质谱有限公司 用于液相样品的快速蒸发电离的系统和方法
JP6320933B2 (ja) * 2011-12-28 2018-05-09 マイクロマス・ユーケー・リミテッド 衝突イオン発生器および分離器
WO2014142925A1 (en) * 2013-03-14 2014-09-18 Empire Technology Development Llc Identification of surgical smoke
US9255907B2 (en) 2013-03-14 2016-02-09 Empire Technology Development Llc Identification of surgical smoke
WO2014142927A1 (en) * 2013-03-14 2014-09-18 Empire Technology Development Llc Identification of surgical smoke
JP6061297B2 (ja) * 2013-05-23 2017-01-18 国立大学法人浜松医科大学 試料分析装置
CN104576287B (zh) * 2013-10-16 2017-05-03 北京理工大学 一种大气压接口的离子源系统以及质谱仪
US20160341712A1 (en) * 2013-10-23 2016-11-24 Brigham And Women's Hospital, Inc. System and method for analyzing tissue intra-operatively using mass spectrometry
US9960028B2 (en) * 2014-06-16 2018-05-01 Purdue Research Foundation Systems and methods for analyzing a sample from a surface
FR3026189B1 (fr) 2014-09-22 2019-11-08 Universite Des Sciences Et Technologies De Lille Dispositif d'analyse moleculaire in vivo en temps reel
US9326838B1 (en) * 2014-10-23 2016-05-03 The North Umpqua Foundation Fish DNA sampler
WO2016090471A1 (en) 2014-12-08 2016-06-16 University Health Network System and method for enhanced mass spectrometry imaging
DE102014226903A1 (de) * 2014-12-23 2016-06-23 Olympus Winter & Ibe Gmbh HF-Hilfsstoff, medizinisches System und Verfahren zum selektiven Behandeln von Krebsgewebe
WO2016109825A1 (en) * 2014-12-31 2016-07-07 Fluidigm Canada Inc. Structured biological samples for analysis by mass cytometry
US11037774B2 (en) 2015-03-06 2021-06-15 Micromass Uk Limited Physically guided rapid evaporative ionisation mass spectrometry (“REIMS”)
CN108700590B (zh) * 2015-03-06 2021-03-02 英国质谱公司 细胞群体分析
GB2553941B (en) 2015-03-06 2021-02-17 Micromass Ltd Chemically guided ambient ionisation mass spectrometry
US10026599B2 (en) 2015-03-06 2018-07-17 Micromass Uk Limited Rapid evaporative ionisation mass spectrometry (“REIMS”) and desorption electrospray ionisation mass spectrometry (“DESI-MS”) analysis of swabs and biopsy samples
US11289320B2 (en) 2015-03-06 2022-03-29 Micromass Uk Limited Tissue analysis by mass spectrometry or ion mobility spectrometry
JP6753862B2 (ja) * 2015-03-06 2020-09-09 マイクロマス ユーケー リミテッド 気体サンプルの改良されたイオン化
KR102092047B1 (ko) * 2015-03-06 2020-03-24 마이크로매스 유케이 리미티드 생체내 내시경 조직 식별 도구
EP3265820B1 (en) 2015-03-06 2023-12-13 Micromass UK Limited Spectrometric analysis of microbes
WO2016142690A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Inlet instrumentation for ion analyser coupled to rapid evaporative ionisation mass spectrometry ("reims") device
KR101956496B1 (ko) 2015-03-06 2019-03-08 마이크로매스 유케이 리미티드 전기수술 응용분야에 대한 액체 트랩 또는 세퍼레이터
CN107646089B (zh) * 2015-03-06 2020-12-08 英国质谱公司 光谱分析
WO2016142685A1 (en) * 2015-03-06 2016-09-15 Micromass Uk Limited Collision surface for improved ionisation
EP3726562B1 (en) * 2015-03-06 2023-12-20 Micromass UK Limited Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue
WO2016142675A1 (en) * 2015-03-06 2016-09-15 Micromass Uk Limited Imaging guided ambient ionisation mass spectrometry
GB2594421A (en) * 2015-03-06 2021-10-27 Micromass Ltd Inlet instrumentation for ion analyser coupled to rapid evaporative ionisation mass spectrometry ("REIMS") device
EP3075321A1 (en) 2015-04-03 2016-10-05 Ryan, Maximillian Frederick A system for generating data relating to a tissue core biopsy, and the use of the system to detect tissue abnormalities, in particular cancerous tissue, in a patient
WO2016168391A1 (en) 2015-04-14 2016-10-20 Waters Technologies Corporation Structural elucidation of isotopically labeled analytes
US9880147B2 (en) 2015-05-29 2018-01-30 Waters Technologies Corporation Free and total fatty acid determination using desorption ionization—mass spectrometry
WO2016196179A1 (en) 2015-05-29 2016-12-08 Waters Technologies Corporation Essential nutrient ratio determination
GB2544834A (en) 2015-06-09 2017-05-31 Waters Technologies Corp Profile diagnositcs in personalized dermatology, dermatopathology and cosmetics
GB2545521B (en) 2015-06-09 2018-11-07 Waters Technologies Corp Molecular diagnostics in personalized dermatology, dermatopathology and cosmetics
RU2598767C1 (ru) * 2015-09-08 2016-09-27 Федеральное государственное бюджетное учреждение "Приволжский федеральный медицинский исследовательский центр" Министерства здравоохранения Российской Федерации Способ интраоперационной навигации при внутримозговых новообразованиях
US11266383B2 (en) 2015-09-22 2022-03-08 University Health Network System and method for optimized mass spectrometry analysis
GB201517195D0 (en) 2015-09-29 2015-11-11 Micromass Ltd Capacitively coupled reims technique and optically transparent counter electrode
GB201521848D0 (en) * 2015-12-11 2016-01-27 Micromass Ltd Feedback apparatus
WO2017109563A1 (en) * 2015-12-21 2017-06-29 Basf Plant Science Company Gmbh Means and methods for determination of a metabolic state of a plant
TWI613442B (zh) 2016-02-23 2018-02-01 國立清華大學 組織辨識方法以及用於組織辨識的生物感測器
WO2017180939A1 (en) 2016-04-14 2017-10-19 Waters Technologies Corporation Rapid authentication using surface desorption ionization and mass spectrometry
US11454611B2 (en) 2016-04-14 2022-09-27 Micromass Uk Limited Spectrometric analysis of plants
TWI684006B (zh) * 2016-04-15 2020-02-01 國立中山大學 人體可代謝物質的檢測方法與檢測系統
WO2017182794A1 (en) * 2016-04-19 2017-10-26 Micromass Uk Limited Transfer tube calibration
GB201609952D0 (en) 2016-06-07 2016-07-20 Micromass Ltd Combined optical and mass spectral tissue ID probes
WO2017214718A2 (en) * 2016-06-10 2017-12-21 University Health Network Soft ionization system and method of use thereof
US9786477B1 (en) * 2016-06-30 2017-10-10 Smiths Detection Inc. Gas flow assisted ion transfer system with improved transfer efficiency
US10643832B2 (en) * 2016-09-02 2020-05-05 Board Of Regents, The University Of Texas System Collection probe and methods for the use thereof
EP3539271A1 (en) * 2016-11-10 2019-09-18 Telefonaktiebolaget LM Ericsson (PUBL) Resource segmentation to improve delivery performance
GB201702643D0 (en) * 2017-02-17 2017-04-05 Micromass Ltd Analysis of food samples
FI20175319A1 (en) * 2017-04-06 2018-10-07 Olfactomics Oy Method and equipment for the analysis of biological samples
JP7025621B2 (ja) * 2017-04-13 2022-02-25 国立大学法人山梨大学 質量分析装置及び質量分析方法、並びに解析装置及び解析方法
KR102086716B1 (ko) * 2017-07-10 2020-03-09 재단법인대구경북과학기술원 살아있는 생체 시료의 분석을 위한 고해상도 대기압 질량분석 이미징 시스템 및 이의 용도
JP7105049B2 (ja) * 2017-10-02 2022-07-22 日本電子株式会社 質量分析データ処理装置、及び質量分析データ処理方法
EP3717901A4 (en) * 2017-11-27 2021-08-25 Board Of Regents, The University Of Texas System MINIMUM INVASION COLLECTION PROBE AND PROCESS FOR USE
CN109841482B (zh) * 2017-11-27 2020-07-21 中国科学院大连化学物理研究所 一种液体样品中挥发性有机物的富集采样和电离装置
CN110085507B (zh) * 2018-01-26 2024-03-26 广州禾信仪器股份有限公司 敞开式离子源系统和质谱仪
WO2019209743A1 (en) * 2018-04-25 2019-10-31 The Regents Of The University Of California Histology-grade three-dimensional imaging of tissue using microscopy with ultraviolet surface excitation
US11219393B2 (en) 2018-07-12 2022-01-11 Trace Matters Scientific Llc Mass spectrometry system and method for analyzing biological samples
RU2702112C1 (ru) * 2019-02-14 2019-10-04 Федеральное государственное бюджетное учреждение "Институт теоретической и экспериментальной физики имени А.И. Алиханова Национального исследовательского центра "Курчатовский институт" Способ восстановления масс для атомно-зондового томографа с лазерным испарением
CN109916881B (zh) * 2019-03-07 2022-02-08 中国科学院上海硅酸盐研究所 激光剥蚀-大气压辉光放电原子发射光谱装置
US11540883B2 (en) * 2019-03-08 2023-01-03 Thomas Jefferson University Virtual reality training for medical events
EP3942291A4 (en) * 2019-03-21 2022-12-14 C2Sense, Inc. VOLATILE ION DETECTION SYSTEMS AND RELATED METHODS
CN111540665A (zh) * 2020-04-20 2020-08-14 清华大学深圳国际研究生院 一种离子化装置及其应用
IT202000013501A1 (it) 2020-06-08 2021-12-08 Univ Degli Studi Magna Graecia Di Catanzaro Dispositivo chirurgico ultra-mininvasivo
CN113984870B (zh) * 2021-12-24 2022-03-22 北京凯世通半导体有限公司 一种通过sims对超低温离子注入设备监测的方法

Family Cites Families (110)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3479545A (en) 1967-05-16 1969-11-18 Hughes Aircraft Co Surface ionization apparatus and electrode means for accelerating the ions in a curved path
JPS5988141A (ja) * 1982-11-12 1984-05-22 株式会社日立製作所 試料ガス採取測定装置
HU191642B (en) 1984-03-21 1987-03-30 Adam Kovacs Method and instrument for discriminating from one another and separating by way of operation organic tissues
JPS6145957A (ja) * 1984-08-10 1986-03-06 Hitachi Ltd 組織物抽出装置
US4935624A (en) * 1987-09-30 1990-06-19 Cornell Research Foundation, Inc. Thermal-assisted electrospray interface (TAESI) for LC/MS
US5779698A (en) * 1989-01-18 1998-07-14 Applied Medical Resources Corporation Angioplasty catheter system and method for making same
US5843019A (en) * 1992-01-07 1998-12-01 Arthrocare Corporation Shaped electrodes and methods for electrosurgical cutting and ablation
JP2785694B2 (ja) * 1994-08-10 1998-08-13 三菱マテリアル株式会社 蒸気圧の高い有機金属化学蒸着による銀薄膜形成用有機銀化合物
JP3415682B2 (ja) 1994-08-10 2003-06-09 株式会社日立製作所 キャピラリー電気泳動・質量分析計
US5559326A (en) 1995-07-28 1996-09-24 Hewlett-Packard Company Self generating ion device for mass spectrometry of liquids
EP0819937A3 (en) * 1996-07-19 2000-03-29 The University Of Nottingham Apparatus and methods for the analysis of trace constituents in gases
US5844149A (en) * 1996-09-19 1998-12-01 Nkk Corporation Method for analyzing solid specimen and apparatus therefor
JPH1151902A (ja) 1997-08-05 1999-02-26 Jeol Ltd Ｌｃ／ｍｓインターフェイス
US5920068A (en) 1998-03-05 1999-07-06 Micron Technology, Inc. Analysis of semiconductor surfaces by secondary ion mass spectrometry
US7329253B2 (en) * 2003-12-09 2008-02-12 Rubicor Medical, Inc. Suction sleeve and interventional devices having such a suction sleeve
EP1153282A2 (de) * 1998-12-14 2001-11-14 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Verfahren und vorrichtungen zur erfassung optischer eigenschaften, insbesondere von lumineszenz-reaktionen und brechungsverhalten, von auf einem träger direkt oder indirekt gebundenen molekülen
CZ20012007A3 (cs) * 1998-12-14 2002-03-13 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Způsoby a zařízení k nanáąení látek na nosič, obzvláątě monomerů, pro kombinatorní syntézu molekulárních knihoven
US7119342B2 (en) 1999-02-09 2006-10-10 Syagen Technology Interfaces for a photoionization mass spectrometer
US6135998A (en) * 1999-03-16 2000-10-24 Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for pulsed plasma-mediated electrosurgery in liquid media
US6280302B1 (en) 1999-03-24 2001-08-28 Flow International Corporation Method and apparatus for fluid jet formation
US6375635B1 (en) 1999-05-18 2002-04-23 Hydrocision, Inc. Fluid jet surgical instruments
AU7867600A (en) 1999-10-08 2001-04-23 General Hospital Corporation, The Methods and apparatus for cell analysis
US6777672B1 (en) 2000-02-18 2004-08-17 Bruker Daltonics, Inc. Method and apparatus for a multiple part capillary device for use in mass spectrometry
DE50110627D1 (de) 2000-06-20 2006-09-14 Medaxis Ag Einrichtung zur erzeugung eines flüssigkeitsstrahles für das entfernen insbesondere von biologischem gewebe
US6825045B2 (en) 2000-08-16 2004-11-30 Vanderbilt University System and method of infrared matrix-assisted laser desorption/ionization mass spectrometry in polyacrylamide gels
CA2364676C (en) 2000-12-08 2010-07-27 Mds Inc., Doing Business As Mds Sciex Ion mobility spectrometer incorporating an ion guide in combination with an ms device
US20030119193A1 (en) 2001-04-25 2003-06-26 Robert Hess System and method for high throughput screening of droplets
JP3725803B2 (ja) 2001-06-15 2005-12-14 株式会社東芝 半導体ウエハの不純物の測定方法及び半導体ウエハの不純物の測定プログラム
EP1291659A3 (en) 2001-09-06 2008-05-21 Sysmex Corporation Automatic sample analyzer and its components
JP2003107054A (ja) 2001-10-01 2003-04-09 Shimadzu Corp 液体クロマトグラフ質量分析装置
US6956206B2 (en) * 2001-10-03 2005-10-18 Drexel University Negative ion atmospheric pressure ionization and selected ion mass spectrometry using a 63NI electron source
WO2003031931A2 (en) 2001-10-05 2003-04-17 Yale University Method and apparatus to produce ions and nanodrops from taylor cones of volatile liquids at reduced pressures
US6756586B2 (en) * 2001-10-15 2004-06-29 Vanderbilt University Methods and apparatus for analyzing biological samples by mass spectrometry
US6610986B2 (en) * 2001-10-31 2003-08-26 Ionfinity Llc Soft ionization device and applications thereof
US7005633B2 (en) 2002-02-08 2006-02-28 Ionalytics Corporation Method and apparatus for desolvating ions for introduction into a FAIMS analyzer region
JP2003247920A (ja) * 2002-02-26 2003-09-05 Tdk Corp 軽元素を含有する固体試料の組成比分析方法
ES2529033T3 (es) 2002-04-26 2015-02-16 Total Research & Technology Feluy Uso de polietileno para preparación de artículos rotomoldeados
AU2003295316A1 (en) * 2002-05-31 2004-04-19 University Of Florida Research Foundation, Inc. Methods and devices for laser desorption chemical ionization
CN2565023Y (zh) * 2002-06-20 2003-08-06 中国科学院广州地球化学研究所 大气细粒子连续液化采集传输装置
AU2003263537A1 (en) 2002-10-10 2004-05-04 Universita' Degli Studi Di Milano Ionization source for mass spectrometry analysis
WO2004034923A1 (de) 2002-10-17 2004-04-29 Braun Gmbh Munddusche und sprühdüse zur erzeugung eines flüssigkeitsstrahls sowie zahnreinigungssystem
JP2004212073A (ja) 2002-12-27 2004-07-29 Hitachi Ltd 危険物探知装置及び危険物探知方法
JP2004264043A (ja) * 2003-01-31 2004-09-24 National Institute Of Advanced Industrial & Technology イオン化装置および微小領域分析装置
KR100466866B1 (ko) 2003-04-24 2005-01-24 전명기 생체조직을 응고괴사시키는 고주파 전기수술기용 전극
US7684934B2 (en) * 2003-06-06 2010-03-23 The United States Of America As Represented By The Department Of Health And Human Services Pattern recognition of whole cell mass spectra
WO2004109254A2 (en) * 2003-06-06 2004-12-16 Ionwerks Fullerene-based maldi matrices for peptides and proteins
US7091477B2 (en) 2003-06-09 2006-08-15 Ionica Mass Spectrometry Group, Inc. Mass spectrometer interface
GB2405081B (en) 2003-07-21 2006-07-12 Fmc Technologies Apparatus and method for portioning using automatic workpiece conveyance speed control
US20050017091A1 (en) 2003-07-22 2005-01-27 Omax Corporation Abrasive water-jet cutting nozzle having a vented water-jet pathway
US20050077644A1 (en) 2003-08-14 2005-04-14 Bryan David E. High pressure liquid jet cutting system and method for forming polymer pellets
US20050112650A1 (en) * 2003-10-20 2005-05-26 Ciphergen Biosystems, Inc. Reactive polyurethane-based polymers
US7217919B2 (en) 2004-11-02 2007-05-15 Analytica Of Branford, Inc. Method and apparatus for multiplexing plural ion beams to a mass spectrometer
US7260914B2 (en) 2003-12-27 2007-08-28 Floral Transport Systems, Llc Method and apparatus for packaging horticultural products
AU2005200016B2 (en) 2004-01-09 2010-12-09 John Bean Technologies Corporation Method and system for portioning workpieces to user-scanned shape and other specifications
US7335897B2 (en) 2004-03-30 2008-02-26 Purdue Research Foundation Method and system for desorption electrospray ionization
US20070023631A1 (en) 2004-03-30 2007-02-01 Zoltan Takats Parallel sample handling for high-throughput mass spectrometric analysis
US7199364B2 (en) 2004-05-21 2007-04-03 Thermo Finnigan Llc Electrospray ion source apparatus
JP3808482B2 (ja) 2004-07-26 2006-08-09 株式会社日立製作所 イオン源、質量分析方法及び質量分析計
US20080262321A1 (en) 2004-08-06 2008-10-23 Ramot At Tel Aviv University Ltd. Early Detection of Harmful Agents: Method, System and Kit
US7094135B2 (en) 2004-08-10 2006-08-22 International Waterjet Parts, Inc. Abrasivejet cutting head with back-flow prevention valve
DE102004053064B4 (de) 2004-11-03 2007-11-08 Bruker Daltonik Gmbh Ionisierung durch Tröpfchenaufprall
US6998622B1 (en) 2004-11-17 2006-02-14 Agilent Technologies, Inc. On-axis electron impact ion source
IL166115A (en) 2005-01-03 2012-06-28 Dan Adam Depth measurement, the sound is based on sound for medical applications
US7735146B2 (en) * 2005-01-27 2010-06-08 The George Washington University Protein microscope
US20060255261A1 (en) * 2005-04-04 2006-11-16 Craig Whitehouse Atmospheric pressure ion source for mass spectrometry
US7138626B1 (en) * 2005-05-05 2006-11-21 Eai Corporation Method and device for non-contact sampling and detection
US7196525B2 (en) 2005-05-06 2007-03-27 Sparkman O David Sample imaging
US7351960B2 (en) 2005-05-16 2008-04-01 Thermo Finnigan Llc Enhanced ion desolvation for an ion mobility spectrometry device
US20070023677A1 (en) 2005-06-29 2007-02-01 Perkins Patrick D Multimode ionization source and method for screening molecules
US20090306341A1 (en) * 2005-07-29 2009-12-10 Joachim Emmert LC/MS Blends Containing Ionizing Additives
US20070046934A1 (en) * 2005-08-26 2007-03-01 New Wave Research, Inc. Multi-function laser induced breakdown spectroscopy and laser ablation material analysis system and method
WO2007041452A2 (en) 2005-09-30 2007-04-12 New York University Methods for preparation of live body tissue for examination
US7828948B1 (en) 2005-10-06 2010-11-09 Sandia Corporation Preconcentration and separation of analytes in microchannels
US20070094389A1 (en) 2005-10-23 2007-04-26 Bill Nussey Provision of rss feeds based on classification of content
US7459676B2 (en) * 2005-11-21 2008-12-02 Thermo Finnigan Llc MALDI/LDI source
JP2007170870A (ja) 2005-12-19 2007-07-05 Protosera Inc 質量分析を用いたｉｎｓｉｔｕ検出方法
RU2328213C2 (ru) * 2005-12-26 2008-07-10 Общество с ограниченной ответственностью "МедМассСпектр" Способ неинвазивного сбора и анализа транскутантного газа из живого организма в режиме реального времени
TWI271771B (en) 2006-01-27 2007-01-21 Univ Nat Sun Yat Sen Electrospray-assisted laser desorption ionization devices, mass spectrometers, and methods for mass spectrometry
US7687772B2 (en) 2006-01-27 2010-03-30 National Sun Yat-Sen University Mass spectrometric imaging method under ambient conditions using electrospray-assisted laser desorption ionization mass spectrometry
JP4818981B2 (ja) * 2006-04-28 2011-11-16 独立行政法人産業技術総合研究所 細胞の迅速識別方法及び識別装置
US7462824B2 (en) 2006-04-28 2008-12-09 Yang Wang Combined ambient desorption and ionization source for mass spectrometry
EP1855306B1 (en) 2006-05-11 2019-11-13 ISB - Ion Source & Biotechnologies S.R.L. Ionization source and method for mass spectrometry
JP2009539114A (ja) 2006-05-26 2009-11-12 イオンセンス インコーポレイテッド 表面イオン化技術で用いるための固体を保持する器具
HU226837B1 (hu) * 2006-05-31 2009-12-28 Semmelweis Egyetem Folyadéksugárral mûködõ deszorpciós ionizációs eljárás és eszköz
JP5142580B2 (ja) 2006-06-29 2013-02-13 キヤノン株式会社 表面解析方法および表面解析装置
US20100044560A1 (en) * 2006-07-06 2010-02-25 Franco Basile Method and Apparatus for Pyrolysis-Induced Cleavage in Peptides and Proteins
WO2008008826A2 (en) 2006-07-11 2008-01-17 Excellims Corporation Methods and apparatus for the ion mobility based separation and collection of molecules
CN101149326A (zh) * 2006-09-21 2008-03-26 中国科学院生态环境研究中心 真空紫外光电离气溶胶质谱仪
WO2008046111A2 (en) 2006-10-13 2008-04-17 Ionsense, Inc. A sampling system for containment and transfer of ions into a spectroscopy system
JP2008147165A (ja) * 2006-10-30 2008-06-26 National Sun Yat-Sen Univ レーザー脱離装置、マススペクトロメーター組立及び環境液体マススペクトロメトリー法
US7718958B2 (en) 2006-11-17 2010-05-18 National Sun Yat-Sen University Mass spectroscopic reaction-monitoring method
US20090065714A1 (en) 2006-11-30 2009-03-12 Keady John P Eletrofluid collisional accelerator and fusion reactor
US8193487B2 (en) 2007-03-16 2012-06-05 Inficon, Inc. Portable light emitting sampling probe
CN101290304A (zh) * 2007-04-17 2008-10-22 中国科学院生态环境研究中心 基质辅助激光解吸电离生物气溶胶质谱仪
US7564028B2 (en) 2007-05-01 2009-07-21 Virgin Instruments Corporation Vacuum housing system for MALDI-TOF mass spectrometry
US20080312651A1 (en) 2007-06-15 2008-12-18 Karl Pope Apparatus and methods for selective heating of tissue
US8901487B2 (en) 2007-07-20 2014-12-02 George Washington University Subcellular analysis by laser ablation electrospray ionization mass spectrometry
US20100186524A1 (en) 2008-02-05 2010-07-29 Enertechnix, Inc Aerosol Collection and Microdroplet Delivery for Analysis
US20100096546A1 (en) 2008-06-23 2010-04-22 Northrop Grumman Systems Corporation Solution Analysis Using Atmospheric Pressure Ionization Techniques
WO2009157312A1 (ja) 2008-06-27 2009-12-30 国立大学法人山梨大学 イオン化分析方法および装置
WO2010039675A1 (en) 2008-09-30 2010-04-08 Prosolia, Inc. Method and apparatus for embedded heater for desorption and ionization of analytes
US20100280409A1 (en) 2008-09-30 2010-11-04 Mark Joseph L Real-time pathology
US8410431B2 (en) 2008-10-13 2013-04-02 Purdue Research Foundation Systems and methods for transfer of ions for analysis
EP2415067B1 (en) * 2009-04-01 2017-12-20 Prosolia, Inc. Method and system for surface sampling
CN102483369B (zh) 2009-05-27 2015-11-25 英国质谱有限公司 用于鉴定生物组织的系统和方法
DE102009050040B4 (de) 2009-08-28 2014-10-30 Bruker Daltonik Gmbh Einlass von Ionen in Massenspektrometer durch Lavaldüsen
US8299444B2 (en) 2009-09-02 2012-10-30 Shimadzu Research Laboratory (Shanghai) Co. Ltd. Ion source
GB2466350B (en) 2009-11-30 2011-06-08 Microsaic Systems Ltd Mass spectrometer system
US8591459B2 (en) 2009-12-21 2013-11-26 Ethicon Endo-Surgery, Inc. Use of biomarkers and therapeutic agents with surgical devices
JP5521177B2 (ja) 2010-04-28 2014-06-11 株式会社島津製作所 質量分析装置

Also Published As

Publication number Publication date
KR101938742B1 (ko) 2019-01-15
JP2015083204A (ja) 2015-04-30
JP6435191B2 (ja) 2018-12-05
CN105342646A (zh) 2016-02-24
MX2011012540A (es) 2012-04-02
HK1217228A1 (zh) 2016-12-30
EP3285059A1 (en) 2018-02-21
AU2010252652B2 (en) 2015-05-07
EP2435814B1 (en) 2017-09-27
KR20170117238A (ko) 2017-10-20
WO2010136887A1 (en) 2010-12-02
AU2010252652A1 (en) 2011-12-15
CN110226948A (zh) 2019-09-13
RU2011151865A (ru) 2013-07-10
CA2763145A1 (en) 2010-12-02
JP2019162498A (ja) 2019-09-26
US20150201913A1 (en) 2015-07-23
JP2012528320A (ja) 2012-11-12
KR101787016B1 (ko) 2017-10-18
JP2017056231A (ja) 2017-03-23
US10959708B2 (en) 2021-03-30
RU2558884C2 (ru) 2015-08-10
CN102483369A (zh) 2012-05-30
US20190321010A1 (en) 2019-10-24
US9046448B2 (en) 2015-06-02
KR20120016150A (ko) 2012-02-22
CN105388205A (zh) 2016-03-09
US10335123B2 (en) 2019-07-02
CN102483369B (zh) 2015-11-25
US20120156712A1 (en) 2012-06-21
CA2763145C (en) 2021-05-25
EP2435814A1 (en) 2012-04-04
CN105342646B (zh) 2019-06-28
JP6594288B2 (ja) 2019-10-23
CN105388205B (zh) 2019-07-23
JP6035145B2 (ja) 2016-11-30
JP6949076B2 (ja) 2021-10-13

Similar Documents

Publication Publication Date Title
HK1217228A1 (zh) 用於鑒定生物組織的系統和方法
IL275599A (en) A system for managing the identification of bacteria in biological samples
IL220669A0 (en) Method and system for tissue recognition
HK1216040A1 (zh) 評估組織的系統和方法
GB2483811B (en) Method and system for integrated analysis
EP2507663A4 (en) SYSTEM AND METHOD FOR MICROSCOPE EXAMINATION OF TIME-BASED BIOLOGICAL SAMPLES
EP2488118A4 (en) System and method for securing tissue to bone
EP2510479A4 (en) SYSTEM AND METHOD FOR IDENTIFICATION OF LABELED ARTICLES
EP2513793A4 (en) Method and system of runtime analysis
IL208420A0 (en) Method and apparatus for cooling biological tissue
EP2334262A4 (en) SYSTEM AND METHOD FOR REALIZING VERTEBRAL SURGERY
IL217110A0 (en) K-wire and method for surgical procedures
GB201209825D0 (en) Surgical access system and related methods
EP2476095A4 (en) Method and system for image analysis of selected tissue structures
EP2496684A4 (en) PHOTOBIOREACTOR SYSTEM AND METHOD OF USE
IL250409B (en) A system and method for the microbilization of embroidery
PL2477551T3 (pl) Sposób pomiaru co najmniej jednej właściwości tkanki biologicznej
GB0806290D0 (en) System for and method of providing information
IL219676A0 (en) Intramedullary system and method
IL200916A0 (en) System and method of extracting plane features
EP2435935A4 (en) METHOD OF PROVIDING A POSTCARD PATENT CARD AND SYSTEM THEREOF
EP2440148A4 (en) LAMINOPLASTING SYSTEM AND METHOD OF APPLICATION THEREFOR
EP2508481A4 (en) DESALINATION SYSTEM AND DESALINATION PROCESS
EP2145952A4 (en) PROCESS FOR THE REMOVAL OF BIOLOGICAL TISSUE
HU0800430D0 (en) Apparatus and method for fixing of biological tissuesamples