HK1207645A1 - Substituted 3,4-dihydro-2h-pyrido[1,2-a]pyrazine-1,6-dione derivatives useful for the treatment of (inter alia) alzheimers disease () 34--2h-[12-a] -16- - Google Patents

Substituted 3,4-dihydro-2h-pyrido[1,2-a]pyrazine-1,6-dione derivatives useful for the treatment of (inter alia) alzheimers disease () 34--2h-[12-a] -16-

Info

Publication number
HK1207645A1
HK1207645A1 HK15108363.5A HK15108363A HK1207645A1 HK 1207645 A1 HK1207645 A1 HK 1207645A1 HK 15108363 A HK15108363 A HK 15108363A HK 1207645 A1 HK1207645 A1 HK 1207645A1
Authority
HK
Hong Kong
Prior art keywords
pyrido
pyrazine
dihydro
substituted
treatment
Prior art date
Application number
HK15108363.5A
Other languages
English (en)
Chinese (zh)
Inventor
Frederik Jan Rita Rombouts
Andrs Avelino Trabanco-Surez
Henricus Jacobus Maria Gijsen
Gregor James Macdonald
Franois Paul Bischoff
Diego Sergio-Alvar Alonso-De
Adriana Ingrid Velter
Yves Emiel Maria Van Roosbroeck
Original Assignee
Janssen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceuticals Inc filed Critical Janssen Pharmaceuticals Inc
Publication of HK1207645A1 publication Critical patent/HK1207645A1/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK15108363.5A 2012-05-16 2015-08-28 Substituted 3,4-dihydro-2h-pyrido[1,2-a]pyrazine-1,6-dione derivatives useful for the treatment of (inter alia) alzheimers disease () 34--2h-[12-a] -16- HK1207645A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP12168186 2012-05-16
EP12195875 2012-12-06
EP12197010 2012-12-13
EP13159178 2013-03-14
PCT/IB2013/054014 WO2013171712A1 (en) 2012-05-16 2013-05-16 Substituted 3, 4 - dihydro - 2h - pyrido [1, 2 -a] pyrazine - 1, 6 - dione derivatives useful for the treatment of (inter alia) alzheimer's disease

Publications (1)

Publication Number Publication Date
HK1207645A1 true HK1207645A1 (en) 2016-02-05

Family

ID=48670031

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15108363.5A HK1207645A1 (en) 2012-05-16 2015-08-28 Substituted 3,4-dihydro-2h-pyrido[1,2-a]pyrazine-1,6-dione derivatives useful for the treatment of (inter alia) alzheimers disease () 34--2h-[12-a] -16-

Country Status (16)

Country Link
US (1) US9181245B2 (ru)
EP (1) EP2850083B1 (ru)
JP (1) JP6106745B2 (ru)
KR (1) KR102096625B1 (ru)
CN (1) CN104583208B (ru)
AU (1) AU2013261023B2 (ru)
BR (1) BR112014028395B1 (ru)
CA (1) CA2870347C (ru)
EA (1) EA027242B1 (ru)
ES (1) ES2585009T3 (ru)
HK (1) HK1207645A1 (ru)
IL (1) IL235659A (ru)
MX (1) MX355164B (ru)
NZ (1) NZ702611A (ru)
SG (1) SG11201407051XA (ru)
WO (1) WO2013171712A1 (ru)

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Also Published As

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CA2870347A1 (en) 2013-11-21
IL235659A0 (en) 2015-02-01
JP2015517517A (ja) 2015-06-22
CA2870347C (en) 2020-08-04
MX355164B (es) 2018-04-06
CN104583208B (zh) 2016-09-28
EP2850083A1 (en) 2015-03-25
EA201492112A1 (ru) 2015-04-30
JP6106745B2 (ja) 2017-04-05
US20150141411A1 (en) 2015-05-21
EP2850083B1 (en) 2016-04-27
MX2014013957A (es) 2015-02-12
KR20150009548A (ko) 2015-01-26
BR112014028395B1 (pt) 2022-02-01
IL235659A (en) 2017-02-28
US9181245B2 (en) 2015-11-10
AU2013261023B2 (en) 2016-11-24
ES2585009T3 (es) 2016-10-03
KR102096625B1 (ko) 2020-04-03
CN104583208A (zh) 2015-04-29
EA027242B1 (ru) 2017-07-31
SG11201407051XA (en) 2014-11-27
BR112014028395A2 (pt) 2017-06-27
AU2013261023A1 (en) 2014-10-30
NZ702611A (en) 2016-10-28
WO2013171712A1 (en) 2013-11-21

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