HK1208454A1 - 治療細菌性疾病的嘧啶衍生物 - Google Patents

治療細菌性疾病的嘧啶衍生物

Info

Publication number
HK1208454A1
HK1208454A1 HK15109091.2A HK15109091A HK1208454A1 HK 1208454 A1 HK1208454 A1 HK 1208454A1 HK 15109091 A HK15109091 A HK 15109091A HK 1208454 A1 HK1208454 A1 HK 1208454A1
Authority
HK
Hong Kong
Prior art keywords
treatment
pyrimidine derivatives
bacterial diseases
bacterial
diseases
Prior art date
Application number
HK15109091.2A
Other languages
English (en)
Inventor
Jean-Franois Bonfanti
Philippe Muller
Frdric Marc Maurice Doublet
Jrme Michel Claude Fortin
Nacer Lounis
Original Assignee
Janssen Sciences Ireland Uc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Uc filed Critical Janssen Sciences Ireland Uc
Publication of HK1208454A1 publication Critical patent/HK1208454A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK15109091.2A 2012-04-30 2015-09-17 治療細菌性疾病的嘧啶衍生物 HK1208454A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12166140 2012-04-30
PCT/EP2013/058980 WO2013164337A1 (en) 2012-04-30 2013-04-30 New compounds and new use

Publications (1)

Publication Number Publication Date
HK1208454A1 true HK1208454A1 (zh) 2016-03-04

Family

ID=48430690

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109091.2A HK1208454A1 (zh) 2012-04-30 2015-09-17 治療細菌性疾病的嘧啶衍生物

Country Status (17)

Country Link
US (2) US9725432B2 (zh)
EP (1) EP2938599B1 (zh)
JP (2) JP6349303B2 (zh)
KR (1) KR102186851B1 (zh)
CN (1) CN104487425B (zh)
AR (1) AR090880A1 (zh)
AU (1) AU2013255843B2 (zh)
BR (1) BR112014026776B1 (zh)
CA (1) CA2868930C (zh)
EA (1) EA030899B1 (zh)
ES (1) ES2676189T3 (zh)
HK (1) HK1208454A1 (zh)
IN (1) IN2014MN02363A (zh)
MX (1) MX358189B (zh)
NZ (2) NZ724424A (zh)
TW (1) TWI598099B (zh)
WO (1) WO2013164337A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR090880A1 (es) * 2012-04-30 2014-12-10 Janssen R & D Ireland Derivados de pirimidina
WO2019121352A1 (en) * 2017-12-20 2019-06-27 Basf Se Herbicidal pyrimidine compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6887870B1 (en) * 1999-10-12 2005-05-03 Bristol-Myers Squibb Company Heterocyclic sodium/proton exchange inhibitors and method
ATE366045T1 (de) 2002-03-15 2007-07-15 Ciba Sc Holding Ag Verwendung von 4-aminopyrimidinen zur antimikrobiellen behandlung von oberflächen
DE102004003493A1 (de) 2004-01-23 2005-08-11 Bayer Cropscience Ag 5-Phenylpyrimidine
TW200716594A (en) 2005-04-18 2007-05-01 Neurogen Corp Substituted heteroaryl CB1 antagonists
BRPI0912029A2 (pt) * 2008-02-01 2020-06-30 Orchid Research Laboratories Limited novos heterociclos
ES2526567T3 (es) 2009-11-18 2015-01-13 Fab Pharma Sas Acrilamidas azaheterocíclicas y su uso como bactericidas
WO2011060976A1 (en) * 2009-11-20 2011-05-26 Universite De Liege Tryptamine-derived compounds as antibacterial agents
JP5697685B2 (ja) * 2009-12-18 2015-04-08 バジリア ファルマスーチカ アーゲーBasilea Pharmaceutica AG 三環式抗生物質
AR090880A1 (es) * 2012-04-30 2014-12-10 Janssen R & D Ireland Derivados de pirimidina

Also Published As

Publication number Publication date
EP2938599A1 (en) 2015-11-04
NZ724424A (en) 2018-02-23
EA201491992A1 (ru) 2015-02-27
AU2013255843A1 (en) 2014-10-23
ES2676189T3 (es) 2018-07-17
KR102186851B1 (ko) 2020-12-07
IN2014MN02363A (zh) 2015-08-14
MX358189B (es) 2018-08-07
WO2013164337A9 (en) 2014-09-18
CN104487425A (zh) 2015-04-01
CA2868930C (en) 2023-11-28
JP6349303B2 (ja) 2018-06-27
US20150087651A1 (en) 2015-03-26
EA030899B1 (ru) 2018-10-31
NZ700507A (en) 2016-09-30
WO2013164337A1 (en) 2013-11-07
JP2015515967A (ja) 2015-06-04
JP6622839B2 (ja) 2019-12-18
AU2013255843B2 (en) 2017-11-02
TWI598099B (zh) 2017-09-11
AR090880A1 (es) 2014-12-10
KR20150003749A (ko) 2015-01-09
BR112014026776A2 (pt) 2017-06-27
EP2938599B1 (en) 2018-04-11
US10221157B2 (en) 2019-03-05
BR112014026776B1 (pt) 2020-03-17
MX2014013165A (es) 2015-01-19
US9725432B2 (en) 2017-08-08
JP2018135338A (ja) 2018-08-30
CA2868930A1 (en) 2013-11-07
CN104487425B (zh) 2016-09-14
TW201350121A (zh) 2013-12-16
US20170334880A1 (en) 2017-11-23

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230427