HK1162306A1 - Replication-defective flavivirus vaccines and vaccine vectors - Google Patents

Replication-defective flavivirus vaccines and vaccine vectors

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Publication number
HK1162306A1
HK1162306A1 HK12102646.0A HK12102646A HK1162306A1 HK 1162306 A1 HK1162306 A1 HK 1162306A1 HK 12102646 A HK12102646 A HK 12102646A HK 1162306 A1 HK1162306 A1 HK 1162306A1
Authority
HK
Hong Kong
Prior art keywords
replication
vaccine vectors
flavivirus vaccines
defective flavivirus
defective
Prior art date
Application number
HK12102646.0A
Other languages
English (en)
Chinese (zh)
Inventor
Konstantin V Pugachev
Alexander A Rumyantsev
Maryann Giel-Moloney
Harold Kleanthous
Original Assignee
Sanofi Pasteur Biologics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Biologics Llc filed Critical Sanofi Pasteur Biologics Llc
Publication of HK1162306A1 publication Critical patent/HK1162306A1/xx

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
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    • A61P31/12Antivirals
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    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
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    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
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    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24141Use of virus, viral particle or viral elements as a vector
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    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24161Methods of inactivation or attenuation
    • C12N2770/24162Methods of inactivation or attenuation by genetic engineering
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HK12102646.0A 2008-03-14 2012-03-15 Replication-defective flavivirus vaccines and vaccine vectors HK1162306A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6945108P 2008-03-14 2008-03-14
US9281408P 2008-08-29 2008-08-29
PCT/US2009/001666 WO2009114207A2 (en) 2008-03-14 2009-03-16 Replication-defective flavivirus vaccines and vaccine vectors

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HK1162306A1 true HK1162306A1 (en) 2012-08-31

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HK12102646.0A HK1162306A1 (en) 2008-03-14 2012-03-15 Replication-defective flavivirus vaccines and vaccine vectors

Country Status (16)

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US (2) US8815564B2 (es)
EP (1) EP2265284A4 (es)
JP (1) JP5779352B2 (es)
KR (1) KR101719316B1 (es)
CN (2) CN105039266A (es)
AU (1) AU2009223727B2 (es)
BR (1) BRPI0908936A2 (es)
CA (1) CA2717499A1 (es)
EA (2) EA201591888A1 (es)
HK (1) HK1162306A1 (es)
IL (1) IL208147A (es)
MX (1) MX2010010034A (es)
SG (1) SG188891A1 (es)
UA (1) UA103316C2 (es)
WO (1) WO2009114207A2 (es)
ZA (1) ZA201006437B (es)

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