HK1159686A1 - Hla-a1101-restricted wt1 peptide and pharmaceutical composition comprising same hla-a1101 wt1 - Google Patents

Hla-a1101-restricted wt1 peptide and pharmaceutical composition comprising same hla-a1101 wt1

Info

Publication number
HK1159686A1
HK1159686A1 HK12100169.1A HK12100169A HK1159686A1 HK 1159686 A1 HK1159686 A1 HK 1159686A1 HK 12100169 A HK12100169 A HK 12100169A HK 1159686 A1 HK1159686 A1 HK 1159686A1
Authority
HK
Hong Kong
Prior art keywords
hla
peptide
restricted
pharmaceutical composition
same
Prior art date
Application number
HK12100169.1A
Other languages
English (en)
Chinese (zh)
Inventor
Haruo Sugiyama
Original Assignee
Int Inst Cancer Immunology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Inst Cancer Immunology Inc filed Critical Int Inst Cancer Immunology Inc
Publication of HK1159686A1 publication Critical patent/HK1159686A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001152—Transcription factors, e.g. SOX or c-MYC
    • A61K39/001153—Wilms tumor 1 [WT1]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464452—Transcription factors, e.g. SOX or c-MYC
    • A61K39/464453—Wilms tumor 1 [WT1]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
HK12100169.1A 2006-12-28 2012-01-06 Hla-a1101-restricted wt1 peptide and pharmaceutical composition comprising same hla-a1101 wt1 HK1159686A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006355356 2006-12-28

Publications (1)

Publication Number Publication Date
HK1159686A1 true HK1159686A1 (en) 2012-08-03

Family

ID=39588385

Family Applications (3)

Application Number Title Priority Date Filing Date
HK12100169.1A HK1159686A1 (en) 2006-12-28 2012-01-06 Hla-a1101-restricted wt1 peptide and pharmaceutical composition comprising same hla-a1101 wt1
HK13100536.6A HK1173187A1 (zh) 2006-12-28 2012-01-06 -限制性 肽及含有其的藥物組合物
HK16109237.6A HK1221252A1 (zh) 2006-12-28 2016-08-03 限制的 肽及含有其的藥物組合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
HK13100536.6A HK1173187A1 (zh) 2006-12-28 2012-01-06 -限制性 肽及含有其的藥物組合物
HK16109237.6A HK1221252A1 (zh) 2006-12-28 2016-08-03 限制的 肽及含有其的藥物組合物

Country Status (28)

Country Link
US (4) US8653038B2 (de)
EP (6) EP2980219B1 (de)
JP (1) JP5484734B2 (de)
KR (1) KR101525261B1 (de)
CN (5) CN101573448B (de)
AR (1) AR064555A1 (de)
AU (1) AU2007340679B2 (de)
BR (1) BRPI0720988A2 (de)
CA (5) CA2886620A1 (de)
CY (1) CY1116011T1 (de)
DK (3) DK2479276T3 (de)
ES (4) ES2629578T3 (de)
HK (3) HK1159686A1 (de)
IL (4) IL199052A0 (de)
MX (1) MX2009007008A (de)
MY (1) MY161664A (de)
NO (1) NO20092774L (de)
NZ (4) NZ592509A (de)
PH (1) PH12014500902B1 (de)
PL (1) PL2341142T3 (de)
PT (1) PT2341142E (de)
RU (1) RU2481398C2 (de)
SG (1) SG177222A1 (de)
SI (1) SI2341142T1 (de)
TW (3) TWI599367B (de)
UA (1) UA103154C2 (de)
WO (1) WO2008081701A1 (de)
ZA (1) ZA200903633B (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100513563C (zh) 2003-11-05 2009-07-15 株式会社国际癌症免疫研究所 Wt1衍生的hla-dr-结合抗原肽
EP2565201B1 (de) 2005-10-17 2014-11-26 Sloan-Kettering Institute For Cancer Research WT1-HLA-Klasse II-bindende Peptide und Zusammensetzungen und Verfahren damit
EP3834836A1 (de) 2006-04-10 2021-06-16 Memorial Sloan Kettering Cancer Center Immunogene wt-1-peptide und verwendungen davon
DK2119778T3 (en) 2007-02-27 2016-01-25 Int Inst Cancer Immunology Inc A process for the activation of the helper T cell, and composition for use in this process
KR20140009168A (ko) * 2010-10-05 2014-01-22 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 헬퍼 ｔ 세포의 활성화 방법
US9074000B2 (en) * 2011-04-01 2015-07-07 Memorial Sloan Kettering Cancer Center T cell receptor-like antibodies specific for a WT1 peptide presented by HLA-A2
CA2846479A1 (en) 2011-09-14 2013-03-21 International Institute Of Cancer Immunology, Inc. Method for measuring anti-wt1 antibody
CA2861206C (en) 2012-01-13 2021-07-06 Richard J. O'reilly Immunogenic wt-1 peptides and methods of use thereof
EP2896693A4 (de) 2012-09-12 2016-10-12 Int Inst Cancer Immunology Inc Antigenspezifische helfer-t-zellen-rezeptorgene
WO2014093118A1 (en) 2012-12-11 2014-06-19 Albert Einstein College Of Medicine Of Yeshiva University Methods for high throughput receptor:ligand identification
MX2015007745A (es) * 2012-12-17 2015-12-15 Otsuka Pharma Co Ltd Metodo para activar la celula t auxiliar.
CN105377291B (zh) 2013-01-15 2019-04-02 纪念斯隆凯特林癌症中心 免疫原性wt-1肽和其使用方法
US10815273B2 (en) 2013-01-15 2020-10-27 Memorial Sloan Kettering Cancer Center Immunogenic WT-1 peptides and methods of use thereof
US10071051B2 (en) 2013-02-05 2018-09-11 Nitto Denko Corporation WT1 peptide cancer vaccine composition for transdermal administration
CN103961698A (zh) 2013-02-05 2014-08-06 日东电工株式会社 经皮或粘膜给予用疫苗组合物
CA2841014A1 (en) 2013-02-05 2014-08-05 Nitto Denko Corporation Tape preparation of wt1 peptide cancer vaccine for transdermal administration
KR20140100419A (ko) 2013-02-05 2014-08-14 닛토덴코 가부시키가이샤 경피 투여용 ｗｔ1 펩티드 암 백신 조성물
US20140220056A1 (en) 2013-02-05 2014-08-07 Nitto Denko Corporation Vaccine composition for transdermal administration
JP6473292B2 (ja) 2013-02-05 2019-02-20 日東電工株式会社 ワクチン組成物
CN103961702B (zh) 2013-02-05 2019-04-09 日东电工株式会社 粘膜给予用wt1肽癌症疫苗组合物
CA2840974A1 (en) 2013-02-05 2014-08-05 Nitto Denko Corporation Vaccine composition for mucosal administration
CN105308063B (zh) * 2013-03-29 2019-11-08 大日本住友制药株式会社 Wt1抗原肽缀合物疫苗
WO2014157704A1 (ja) * 2013-03-29 2014-10-02 大日本住友製薬株式会社 Ｅｒａｐ１によるトリミング機能をきっかけとしたコンジュゲートワクチン
CA2970236A1 (en) * 2014-12-11 2016-06-16 International Institute Of Cancer Immunology, Inc. Compositions comprising wt1 peptide for immunotherapy of angiogenic disease
BR112018073606A2 (pt) 2016-05-18 2019-02-26 Cue Biopharma, Inc. polipeptídeos multiméricos moduladores de células t e métodos de uso dos mesmos
JP2019522466A (ja) 2016-05-18 2019-08-15 アルバート アインシュタイン カレッジ オブ メディシン，インコーポレイティド 変異ｐｄ−ｌ１ポリペプチド、ｔ細胞調節多量体ポリペプチド、及びそれらの使用方法
CN116970061A (zh) 2016-12-22 2023-10-31 库尔生物制药有限公司 T细胞调节性多聚体多肽及其使用方法
WO2018129474A1 (en) 2017-01-09 2018-07-12 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
EP3596118A4 (de) 2017-03-15 2021-04-07 Cue Biopharma, Inc. Verfahren zur modulierung einer immunreaktion
CN111741972A (zh) * 2017-12-27 2020-10-02 大日本住友制药株式会社 Wt1衍生肽的缀合物和包含其的组合物
EP3737689A4 (de) 2018-01-09 2021-12-01 Cue Biopharma, Inc. Multimere t-zell-modulierende polypeptide und verfahren zur verwendung davon
EP4151227A1 (de) * 2020-05-12 2023-03-22 Sumitomo Pharma Co., Ltd. Pharmazeutische zusammensetzung zur behandlung von krebs
CA3169949A1 (en) 2020-05-12 2021-11-18 Cue Biopharma, Inc. Multimeric t-cell modulatory polypeptides and methods of use thereof

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4575374A (en) * 1983-02-16 1986-03-11 Anis Aziz Y Flexible anterior chamber lens
US5763209A (en) 1988-09-26 1998-06-09 Arch Development Corporation Methods and materials relating to the functional domains of DNA binding proteins
US5584304A (en) * 1993-11-18 1996-12-17 Allergan, Inc. Method of inserting an IOL using a forceps inside a folding tube
US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
US5984962A (en) * 1996-01-22 1999-11-16 Quantum Vision, Inc. Adjustable intraocular lens
US6207375B1 (en) * 1996-12-11 2001-03-27 Mayo Foundation For Medical Educational & Research TGF-β inducible early factor-1 (TIEF-1) and a method to detect breast cancer
US7063854B1 (en) * 1998-09-30 2006-06-20 Corixa Corporation Composition and methods for WTI specific immunotherapy
US7115272B1 (en) 1998-09-30 2006-10-03 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7901693B2 (en) 1998-09-30 2011-03-08 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US20030039635A1 (en) 1998-09-30 2003-02-27 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7655249B2 (en) * 1998-09-30 2010-02-02 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
AU6407899A (en) * 1998-09-30 2000-04-17 Corixa Corporation Compositions and methods for wt1 specific immunotherapy
US7144581B2 (en) * 2000-10-09 2006-12-05 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US20030072767A1 (en) 1998-09-30 2003-04-17 Alexander Gaiger Compositions and methods for WT1 specific immunotherapy
US20030235557A1 (en) * 1998-09-30 2003-12-25 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
ES2308976T3 (es) * 1999-04-02 2008-12-16 Corixa Corporation Compuestos y metodos para la terapia y el diagnostico del cancer de pulmon.
AU7859900A (en) * 1999-10-04 2001-05-10 Corixa Corporation Compositions and methods for wt1 specific immunotherapy
US20030082194A1 (en) * 2000-02-22 2003-05-01 Alexander Gaiger Compositions and methods for diagnosis and therapy of malignant mesothelioma
NZ521430A (en) 2000-02-22 2004-04-30 Corixa Corp Compositions comprising 1-4 antigenic peptide fragments of the Wilms' tumour gene product for treatment or prevention of malignant mesothelioma
US20040097703A1 (en) * 2001-03-22 2004-05-20 Haruo Sugiyama Wt1 modified peptide
IL145015A0 (en) * 2001-08-21 2002-06-30 Nun Yehoshua Ben Accommodating lens
US7553494B2 (en) * 2001-08-24 2009-06-30 Corixa Corporation WT1 fusion proteins
JP4365784B2 (ja) 2002-06-12 2009-11-18 株式会社癌免疫研究所 Ｈｌａ−ａ２４拘束性癌抗原ペプチド
ATE446094T1 (de) * 2002-06-14 2009-11-15 Merck & Co Inc Mitotische kinesin-hemmer
SE0201863D0 (en) * 2002-06-18 2002-06-18 Cepep Ab Cell penetrating peptides
KR101399678B1 (ko) 2003-01-15 2014-05-27 추가이 세이야쿠 가부시키가이샤 이량체화 펩티드
US7976520B2 (en) * 2004-01-12 2011-07-12 Nulens Ltd. Eye wall anchored fixtures
US7622119B2 (en) 2004-03-31 2009-11-24 International Institute Of Cancer Immunology, Inc. Cancer antigen peptides derived from WT1
JP2006045287A (ja) 2004-08-02 2006-02-16 Inax Corp 弾性接着剤及びタイル張り壁面
JP4719876B2 (ja) * 2005-04-04 2011-07-06 国立大学法人愛媛大学 Ｈｌａクラスｉｉ拘束性ｗｔ１抗原ペプチド
WO2010037395A2 (en) * 2008-10-01 2010-04-08 Dako Denmark A/S Mhc multimers in cancer vaccines and immune monitoring

Also Published As

Publication number Publication date
PH12014500902A1 (en) 2016-01-11
IL199052A0 (en) 2010-03-28
US20180064795A1 (en) 2018-03-08
AU2007340679A1 (en) 2008-07-10
NO20092774L (no) 2009-07-27
CY1116011T1 (el) 2017-01-25
JPWO2008081701A1 (ja) 2010-04-30
SG177222A1 (en) 2012-01-30
PH12014500902B1 (en) 2016-01-11
WO2008081701A1 (ja) 2008-07-10
CA2886622A1 (en) 2008-07-10
ES2526425T3 (es) 2015-01-12
CN102302788B (zh) 2016-06-15
RU2481398C2 (ru) 2013-05-10
TWI599367B (zh) 2017-09-21
DK2479276T3 (en) 2015-12-21
CN102335439B (zh) 2015-04-22
MX2009007008A (es) 2009-07-10
IL215333A0 (en) 2011-11-30
HK1173187A1 (zh) 2013-05-10
EP2098595A4 (de) 2010-03-17
EP2980219B1 (de) 2018-11-14
CA2670658A1 (en) 2008-07-10
CA2886619A1 (en) 2008-07-10
DK2341142T3 (en) 2014-12-08
CN102659924B (zh) 2015-11-25
EP2479275A1 (de) 2012-07-25
EP2980219A1 (de) 2016-02-03
KR101525261B1 (ko) 2015-06-02
TW201345544A (zh) 2013-11-16
EP3026115A1 (de) 2016-06-01
ES2556831T3 (es) 2016-01-20
EP2341142B8 (de) 2015-01-14
EP2479276B1 (de) 2015-12-09
CN101573448A (zh) 2009-11-04
EP2098595A1 (de) 2009-09-09
TW201630620A (zh) 2016-09-01
IL215332A0 (en) 2011-11-30
EP2479276A1 (de) 2012-07-25
AU2007340679B2 (en) 2013-09-12
SI2341142T1 (sl) 2015-03-31
NZ601175A (en) 2012-12-21
US9272026B2 (en) 2016-03-01
US20140134200A1 (en) 2014-05-15
AR064555A1 (es) 2009-04-08
NZ577443A (en) 2011-12-22
DK2479275T3 (en) 2015-12-14
US20160199472A1 (en) 2016-07-14
NZ592509A (en) 2012-11-30
CN102302788A (zh) 2012-01-04
PT2341142E (pt) 2015-02-13
ES2554775T3 (es) 2015-12-23
TWI554280B (zh) 2016-10-21
CN102335439A (zh) 2012-02-01
CA2886621A1 (en) 2008-07-10
US20110098233A1 (en) 2011-04-28
CN102295682A (zh) 2011-12-28
KR20090102772A (ko) 2009-09-30
JP5484734B2 (ja) 2014-05-07
TWI417103B (zh) 2013-12-01
PL2341142T3 (pl) 2015-04-30
ZA200903633B (en) 2010-02-24
RU2009128979A (ru) 2011-02-10
CA2886620A1 (en) 2008-07-10
TW200835513A (en) 2008-09-01
BRPI0720988A2 (pt) 2014-03-18
MY161664A (en) 2017-04-28
CN102659924A (zh) 2012-09-12
EP2341142A3 (de) 2011-09-07
EP2341142B1 (de) 2014-11-26
ES2629578T3 (es) 2017-08-11
EP3026115B1 (de) 2017-05-17
EP2479275B1 (de) 2015-10-28
CN101573448B (zh) 2012-07-11
NZ592510A (en) 2012-11-30
HK1221252A1 (zh) 2017-05-26
IL215334A0 (en) 2011-11-30
US8653038B2 (en) 2014-02-18
EP2341142A2 (de) 2011-07-06
UA103154C2 (uk) 2013-09-25

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