PT2341142E - Péptido wt1 restringido a hla-a*1101 e composição farmacêutica compreendendo o mesmo - Google Patents

Péptido wt1 restringido a hla-a*1101 e composição farmacêutica compreendendo o mesmo Download PDF

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Publication number
PT2341142E
PT2341142E PT101912343T PT10191234T PT2341142E PT 2341142 E PT2341142 E PT 2341142E PT 101912343 T PT101912343 T PT 101912343T PT 10191234 T PT10191234 T PT 10191234T PT 2341142 E PT2341142 E PT 2341142E
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PT
Portugal
Prior art keywords
hla
peptide
restricted
same
pharmaceutical composition
Prior art date
Application number
PT101912343T
Other languages
English (en)
Original Assignee
Int Inst Cancer Immunology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Inst Cancer Immunology Inc filed Critical Int Inst Cancer Immunology Inc
Publication of PT2341142E publication Critical patent/PT2341142E/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001152Transcription factors, e.g. SOX or c-MYC
    • A61K39/001153Wilms tumor 1 [WT1]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643Vertebrate antigens
    • A61K39/4644Cancer antigens
    • A61K39/464452Transcription factors, e.g. SOX or c-MYC
    • A61K39/464453Wilms tumor 1 [WT1]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5158Antigen-pulsed cells, e.g. T-cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
PT101912343T 2006-12-28 2007-12-14 Péptido wt1 restringido a hla-a*1101 e composição farmacêutica compreendendo o mesmo PT2341142E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006355356 2006-12-28

Publications (1)

Publication Number Publication Date
PT2341142E true PT2341142E (pt) 2015-02-13

Family

ID=39588385

Family Applications (1)

Application Number Title Priority Date Filing Date
PT101912343T PT2341142E (pt) 2006-12-28 2007-12-14 Péptido wt1 restringido a hla-a*1101 e composição farmacêutica compreendendo o mesmo

Country Status (28)

Country Link
US (4) US8653038B2 (pt)
EP (6) EP2479275B1 (pt)
JP (1) JP5484734B2 (pt)
KR (1) KR101525261B1 (pt)
CN (5) CN102295682A (pt)
AR (1) AR064555A1 (pt)
AU (1) AU2007340679B2 (pt)
BR (1) BRPI0720988A2 (pt)
CA (5) CA2886622A1 (pt)
CY (1) CY1116011T1 (pt)
DK (3) DK2479276T3 (pt)
ES (4) ES2554775T3 (pt)
HK (3) HK1159686A1 (pt)
IL (4) IL199052A0 (pt)
MX (1) MX2009007008A (pt)
MY (1) MY161664A (pt)
NO (1) NO20092774L (pt)
NZ (4) NZ601175A (pt)
PH (1) PH12014500902A1 (pt)
PL (1) PL2341142T3 (pt)
PT (1) PT2341142E (pt)
RU (1) RU2481398C2 (pt)
SG (1) SG177222A1 (pt)
SI (1) SI2341142T1 (pt)
TW (3) TWI417103B (pt)
UA (1) UA103154C2 (pt)
WO (1) WO2008081701A1 (pt)
ZA (1) ZA200903633B (pt)

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EP3117836A1 (en) 2006-04-10 2017-01-18 Sloan Kettering Institute For Cancer Research Immunogenic wt-1 peptides and uses thereof
RU2680539C2 (ru) 2007-02-27 2019-02-22 Интернешнл Инститьют Оф Кэнсер Иммунолоджи, Инк. Способ активации хелперных т-клеток и композиция для применения в данном способе
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SG193956A1 (en) * 2011-04-01 2013-11-29 Sloan Kettering Inst Cancer T cell receptor-like antibodies specific for a wt1 peptide presented by hla-a2
EP2757373A4 (en) * 2011-09-14 2015-07-01 Int Inst Cancer Immunology Inc METHOD FOR MEASURING ANTI-WT1 ANTIBODIES
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KR102208505B1 (ko) 2012-12-11 2021-01-27 앨버트 아인슈타인 컬리지 오브 메디신 고처리량 수용체:리간드 확인을 위한 방법
TWI646970B (zh) * 2012-12-17 2019-01-11 大塚製藥股份有限公司 活化輔助t細胞的方法
PT2945647T (pt) 2013-01-15 2020-11-26 Memorial Sloan Kettering Cancer Center Péptidos imunogénicos wt-1 e métodos de uso dos mesmos
US10815273B2 (en) 2013-01-15 2020-10-27 Memorial Sloan Kettering Cancer Center Immunogenic WT-1 peptides and methods of use thereof
RU2014102939A (ru) 2013-02-05 2015-08-10 Нитто Денко Корпорейшн Вакцинная композиция для чрескожного введения
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KR20140099828A (ko) 2013-02-05 2014-08-13 닛토덴코 가부시키가이샤 점막 투여용 백신 조성물
JP6512567B2 (ja) 2013-02-05 2019-05-15 日東電工株式会社 経皮投与用wt1ペプチド癌ワクチン組成物
JP6671956B2 (ja) * 2013-03-29 2020-03-25 大日本住友製薬株式会社 Erap1によるトリミング機能をきっかけとしたコンジュゲートワクチン
RU2668560C2 (ru) * 2013-03-29 2018-10-02 Сумитомо Дайниппон Фарма Ко., Лтд. Конъюгированная вакцина на основе пептида антигена wt1
EP3231438B1 (en) 2014-12-11 2020-06-17 International Institute of Cancer Immunology, Inc. Wt1 immunotherapy for intraocular angiogenic disease
EP3458095A4 (en) 2016-05-18 2019-11-27 Albert Einstein College of Medicine PD-L1 POLYPEPTIDE VARIANTS, T-LYMPHOCYTE MODULATOR MULTIMERIC POLYPEPTIDES AND METHODS OF USING SAME
CN109475628A (zh) 2016-05-18 2019-03-15 库尔生物制药有限公司 T细胞调节性多聚体多肽及其使用方法
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Also Published As

Publication number Publication date
JPWO2008081701A1 (ja) 2010-04-30
EP2980219A1 (en) 2016-02-03
NZ577443A (en) 2011-12-22
CN102335439A (zh) 2012-02-01
EP2341142B1 (en) 2014-11-26
TW201345544A (zh) 2013-11-16
NZ601175A (en) 2012-12-21
AU2007340679B2 (en) 2013-09-12
US20140134200A1 (en) 2014-05-15
CA2886620A1 (en) 2008-07-10
TW201630620A (zh) 2016-09-01
CN102302788A (zh) 2012-01-04
CN102335439B (zh) 2015-04-22
KR20090102772A (ko) 2009-09-30
IL215334A0 (en) 2011-11-30
IL215332A0 (en) 2011-11-30
TWI599367B (zh) 2017-09-21
US9272026B2 (en) 2016-03-01
US8653038B2 (en) 2014-02-18
CA2886621A1 (en) 2008-07-10
KR101525261B1 (ko) 2015-06-02
CN101573448B (zh) 2012-07-11
ES2554775T3 (es) 2015-12-23
DK2479275T3 (en) 2015-12-14
MX2009007008A (es) 2009-07-10
JP5484734B2 (ja) 2014-05-07
TW200835513A (en) 2008-09-01
CA2886619A1 (en) 2008-07-10
EP2980219B1 (en) 2018-11-14
UA103154C2 (uk) 2013-09-25
EP2479275A1 (en) 2012-07-25
HK1221252A1 (zh) 2017-05-26
EP3026115B1 (en) 2017-05-17
AR064555A1 (es) 2009-04-08
ZA200903633B (en) 2010-02-24
CN102302788B (zh) 2016-06-15
NZ592510A (en) 2012-11-30
RU2009128979A (ru) 2011-02-10
SG177222A1 (en) 2012-01-30
EP2479276A1 (en) 2012-07-25
CN102295682A (zh) 2011-12-28
EP2098595A4 (en) 2010-03-17
CY1116011T1 (el) 2017-01-25
TWI417103B (zh) 2013-12-01
WO2008081701A1 (ja) 2008-07-10
ES2556831T3 (es) 2016-01-20
IL215333A0 (en) 2011-11-30
EP2479275B1 (en) 2015-10-28
IL199052A0 (en) 2010-03-28
SI2341142T1 (sl) 2015-03-31
AU2007340679A1 (en) 2008-07-10
US20180064795A1 (en) 2018-03-08
PH12014500902B1 (en) 2016-01-11
CN102659924A (zh) 2012-09-12
BRPI0720988A2 (pt) 2014-03-18
EP2341142B8 (en) 2015-01-14
EP2479276B1 (en) 2015-12-09
CA2670658A1 (en) 2008-07-10
EP2341142A3 (en) 2011-09-07
HK1173187A1 (zh) 2013-05-10
DK2479276T3 (en) 2015-12-21
CA2886622A1 (en) 2008-07-10
ES2526425T3 (es) 2015-01-12
US20160199472A1 (en) 2016-07-14
CN101573448A (zh) 2009-11-04
DK2341142T3 (en) 2014-12-08
RU2481398C2 (ru) 2013-05-10
ES2629578T3 (es) 2017-08-11
HK1159686A1 (en) 2012-08-03
EP2341142A2 (en) 2011-07-06
PH12014500902A1 (en) 2016-01-11
MY161664A (en) 2017-04-28
PL2341142T3 (pl) 2015-04-30
EP2098595A1 (en) 2009-09-09
TWI554280B (zh) 2016-10-21
CN102659924B (zh) 2015-11-25
US20110098233A1 (en) 2011-04-28
NZ592509A (en) 2012-11-30
NO20092774L (no) 2009-07-27
EP3026115A1 (en) 2016-06-01

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