HK1150728A1 - Quinolone analogs and methods related thereto - Google Patents

Quinolone analogs and methods related thereto

Info

Publication number
HK1150728A1
HK1150728A1 HK11104885.7A HK11104885A HK1150728A1 HK 1150728 A1 HK1150728 A1 HK 1150728A1 HK 11104885 A HK11104885 A HK 11104885A HK 1150728 A1 HK1150728 A1 HK 1150728A1
Authority
HK
Hong Kong
Prior art keywords
methods related
quinolone analogs
quinolone
analogs
methods
Prior art date
Application number
HK11104885.7A
Other languages
English (en)
Chinese (zh)
Inventor
‧納卡薩瓦
‧皮埃爾
‧哈達奇
‧施瓦貝比
‧達加尼亞
‧惠藤
Original Assignee
生華生物科技股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 生華生物科技股份有限公司 filed Critical 生華生物科技股份有限公司
Publication of HK1150728A1 publication Critical patent/HK1150728A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epidemiology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK11104885.7A 2007-10-05 2011-05-17 Quinolone analogs and methods related thereto HK1150728A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US97804207P 2007-10-05 2007-10-05
US3868108P 2008-03-21 2008-03-21
US4593308P 2008-04-17 2008-04-17
PCT/US2008/078859 WO2009046383A1 (en) 2007-10-05 2008-10-03 Quinolone analogs and methods related thereto

Publications (1)

Publication Number Publication Date
HK1150728A1 true HK1150728A1 (en) 2012-01-13

Family

ID=40523786

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11104885.7A HK1150728A1 (en) 2007-10-05 2011-05-17 Quinolone analogs and methods related thereto

Country Status (19)

Country Link
US (2) US7928100B2 (xx)
EP (2) EP3092901B1 (xx)
JP (2) JP5824213B2 (xx)
KR (2) KR101682867B1 (xx)
CN (1) CN101888780B (xx)
AU (1) AU2008308485B2 (xx)
BR (1) BRPI0817806A2 (xx)
CA (1) CA2701630C (xx)
DK (1) DK3092901T3 (xx)
ES (2) ES2582662T3 (xx)
HK (1) HK1150728A1 (xx)
IL (2) IL204844A (xx)
MX (1) MX2010003685A (xx)
NO (1) NO20100596L (xx)
NZ (1) NZ584892A (xx)
PL (2) PL2214491T3 (xx)
PT (2) PT2214491T (xx)
RU (1) RU2549895C2 (xx)
WO (1) WO2009046383A1 (xx)

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CN103533934B (zh) 2011-03-17 2016-03-30 特尔汗什莫尔医学基础设施研究和服务公司 用于治疗自身免疫性疾病的喹诺酮类似物
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CN104177379B (zh) * 2013-05-22 2016-12-28 中国科学院上海药物研究所 一种喹诺酮类化合物或其立体化学异构体、包含该化合物的药物组合物及其用途
WO2015079411A1 (en) * 2013-11-28 2015-06-04 Tel Hashomer Medical Research Infrastructure And Services Ltd. Rna polymerase i inhibitors and uses thereof
KR101890505B1 (ko) * 2014-05-09 2018-09-28 피메라, 아이엔씨. 신규한 조성물, 용도 및 이를 제조하기 위한 방법
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
CN108601789A (zh) 2015-11-20 2018-09-28 生华生物科技股份有限公司 用于治疗癌症的四环喹诺酮类似物组合疗法
EP3394070B1 (en) * 2015-12-14 2023-08-02 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
TWI765848B (zh) * 2015-12-14 2022-06-01 生華生物科技股份有限公司 喹諾酮類似物及其鹽的結晶形式
US9957282B2 (en) 2015-12-14 2018-05-01 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
JP2020512975A (ja) 2017-03-28 2020-04-30 ピメラ，インク． Ｐｏｌ１阻害剤の新規な結晶形態
US11071727B2 (en) 2018-01-26 2021-07-27 Northwestern University Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors
CA3088998A1 (en) * 2018-02-15 2019-09-06 Senhwa Biosciences, Inc. Quinolone analogs and their salts, compositions, and method for their use
WO2020051342A1 (en) * 2018-09-06 2020-03-12 Cornell University Methods for treating metastatic disease using ribosome biogenesis inhibitor cx 5461
KR20220130085A (ko) * 2019-08-14 2022-09-26 센화 바이오사이언시즈 인코포레이티드 테트라사이클릭 화합물 및 이의 염, 조성물, 및 이의 사용 방법
BR112022002772A2 (pt) * 2019-08-14 2022-08-09 Senhwa Biosciences Inc Formas cristalinas de análogos de quinolina e sais dos mesmos, composições e seus métodos para uso
JP2020189888A (ja) * 2020-08-28 2020-11-26 センワ バイオサイエンシズ インコーポレイテッド キノロン類似体及びその塩の結晶形
CN114573604B (zh) * 2020-12-01 2024-06-18 中国科学院上海药物研究所 一类基于喹诺酮的化合物、其制备方法、包含其的药物组合物及其用途
MX2023011004A (es) 2021-03-19 2024-01-08 Trained Therapeutix Discovery Inc Compuestos para regular la inmunidad entrenada y métodos para usarlos.
CN114409681A (zh) * 2022-03-18 2022-04-29 信义核新(北京)生物科技有限公司 用于治疗dna损伤修复缺陷肿瘤的喹诺酮类似物及其应用

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Also Published As

Publication number Publication date
JP2010540663A (ja) 2010-12-24
AU2008308485B2 (en) 2014-08-07
IL249906B (en) 2020-10-29
KR101601332B1 (ko) 2016-03-08
EP2214491A4 (en) 2010-11-10
IL204844A0 (en) 2010-11-30
JP5824213B2 (ja) 2015-11-25
ES2791305T3 (es) 2020-11-03
BRPI0817806A2 (pt) 2014-10-07
IL204844A (en) 2017-01-31
RU2549895C2 (ru) 2015-05-10
EP2214491A1 (en) 2010-08-11
JP2014159474A (ja) 2014-09-04
US7928100B2 (en) 2011-04-19
US8853234B2 (en) 2014-10-07
KR20100064392A (ko) 2010-06-14
CA2701630C (en) 2016-10-25
PT2214491T (pt) 2016-10-25
MX2010003685A (es) 2010-06-02
CN101888780B (zh) 2014-08-13
IL249906A0 (en) 2017-03-30
EP3092901A1 (en) 2016-11-16
PL2214491T3 (pl) 2016-11-30
CN101888780A (zh) 2010-11-17
US20110218184A1 (en) 2011-09-08
DK3092901T3 (da) 2020-05-18
KR101682867B1 (ko) 2016-12-05
RU2010117225A (ru) 2011-11-10
PT3092901T (pt) 2020-05-21
ES2582662T3 (es) 2016-09-14
NO20100596L (no) 2010-06-10
EP3092901B1 (en) 2020-04-29
US20090093455A1 (en) 2009-04-09
WO2009046383A1 (en) 2009-04-09
NZ584892A (en) 2012-06-29
EP2214491B1 (en) 2016-07-13
PL3092901T3 (pl) 2020-10-19
KR20160020578A (ko) 2016-02-23
AU2008308485A1 (en) 2009-04-09
CA2701630A1 (en) 2009-04-09

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